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Transport of aromatic amino acids l‐tryptophan, l‐tyrosine, and l‐phenylalanine by the organic anion transporting polypeptide (OATP) 3A1.
- Published in:
- FEBS Journal, 2024, v. 291, n. 21, p. 4732, doi. 10.1111/febs.17255
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- Article
Optimizing Medication Safety with Oral Antitumor Therapy: A Methodological Approach for the Real-World Implementation of the AMBORA Competence and Consultation Center.
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- Healthcare (2227-9032), 2023, v. 11, n. 11, p. 1640, doi. 10.3390/healthcare11111640
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- Article
Transcriptional Regulation of Liver-Type OATP1B3 (Lt-OATP1B3) and Cancer-Type OATP1B3 (Ct-OATP1B3) Studied in Hepatocyte-Derived and Colon Cancer-Derived Cell Lines.
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- Pharmaceutics, 2023, v. 15, n. 3, p. 738, doi. 10.3390/pharmaceutics15030738
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- Article
Interaction of Remdesivir with Clinically Relevant Hepatic Drug Uptake Transporters.
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- Pharmaceutics, 2021, v. 13, n. 3, p. 369, doi. 10.3390/pharmaceutics13030369
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- Article
Transporter-Mediated Drug-Drug Interactions with Oral Antidiabetic Drugs.
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- Pharmaceutics, 2011, v. 3, n. 4, p. 680, doi. 10.3390/pharmaceutics3040680
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- Article
Drugs linked to plasma homoarginine in chronic kidney disease patients—a cross-sectional analysis of the German Chronic Kidney Disease cohort.
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- Nephrology Dialysis Transplantation, 2020, v. 35, n. 7, p. 1187, doi. 10.1093/ndt/gfy342
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- Article
L-Arginine and Cardioactive Arginine Derivatives as Substrates and Inhibitors of Human and Mouse NaCT/Nact.
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- Metabolites (2218-1989), 2022, v. 12, n. 4, p. N.PAG, doi. 10.3390/metabo12040273
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- Article
Transport of Drugs and Endogenous Compounds Mediated by Human OCT1: Studies in Single- and Double-Transfected Cell Models.
- Published in:
- Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.662535
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- Article
Heteroaryl derivatives of suvorexant as OX1R selective PET ligand candidates: Cu-mediated <sup>18</sup>F-fluorination of boroxines, in vitro and initial in vivo evaluation.
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- EJNMMI Research, 2024, v. 14, n. 1, p. 1, doi. 10.1186/s13550-024-01141-2
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- Article
Inhibitory Effects of Green Tea and (–)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein.
- Published in:
- PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0139370
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- Article
Substrate-Dependent Inhibition of the Human Organic Cation Transporter OCT2: A Comparison of Metformin with Experimental Substrates.
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- PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0136451
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- Article
<i>Alanine-glyoxylate aminotransferase 2</i> (<i>AGXT2</i>) Polymorphisms Have Considerable Impact on Methylarginine and β-aminoisobutyrate Metabolism in Healthy Volunteers.
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- PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088544
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- Article
Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4–dependent pharmacokinetics in humans<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2006, v. 79, n. 5, p. 449, doi. 10.1016/j.clpt.2006.01.005
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- Article
Grapefruit juice ingestion significantly reduces talinolol bioavailability.
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- Clinical Pharmacology & Therapeutics, 2005, v. 77, n. 4, p. 291, doi. 10.1016/j.clpt.2004.11.111
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- Article
Impact of concentration and rate of intraluminal drug delivery on absorption and gut wall metabolism of verapamil in humans<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2004, v. 76, n. 3, p. 230, doi. 10.1016/j.clpt.2004.04.013
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- Article
Cytochrome P450 3A4 and P-glycoprotein Expression in Human Small Intestinal Enterocytes and Hepatocytes: A Comparative Analysis in Paired Tissue Specimens<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 3, p. 172, doi. 10.1016/j.clpt.2003.10.008
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- Article
Celecoxib inhibits metabolism of cytochrome P450 2D6 substrate metoprolol in humans<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2003, v. 74, n. 2, p. 130, doi. 10.1016/S0009-9236(03)00120-6
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- Article
P-glycoprotein-mediated intestinal and biliary digoxin transport in humans<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2003, v. 73, n. 3, p. 223, doi. 10.1067/mcp.2003.27
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- Article
Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2002, v. 72, n. 5, p. 584, doi. 10.1067/mcp.2002.129196
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- Article
Shed human enterocytes as a tool for the study of expression and function of intestinal drug-metabolizing enzymes and transporters<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2002, v. 71, n. 3, p. 131, doi. 10.1067/mcp.2002.121370
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- Article
Determination of in vivo absorption, metabolism, and transport of drugs by the human intestinal wall and liver with a novel perfusion technique<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2001, v. 70, n. 3, p. 217, doi. 10.1067/mcp.2001.117937
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- Article
Disposition and pharmacologic effects of R/S-verapamil in patients with chronic atrial fibrillation: An investigation comparing single and multiple dosing<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2001, v. 69, n. 5, p. 324, doi. 10.1067/mcp.2001.115125
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- Article
Dihydrocodeine: A new opioid substrate for the polymorphic CYP2D6 in humans<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 1995, v. 58, n. 4, p. 374, doi. 10.1016/0009-9236(95)90049-7
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- Article
Documentation of Drug-Related Problems with ICD-11: Application of the New WHO Code-Set to Clinical Routine Data.
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- Journal of Clinical Medicine, 2023, v. 12, n. 1, p. 315, doi. 10.3390/jcm12010315
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- Article
Characteristics and Cost of Unscheduled Hospitalizations in Patients Treated with New Oral Anticancer Drugs in Germany: Evidence from the Randomized AMBORA Trial.
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- Journal of Clinical Medicine, 2022, v. 11, n. 21, p. 6392, doi. 10.3390/jcm11216392
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- Article
New Oral Antitumor Drugs and Medication Safety in Uro-Oncology: Implications for Clinical Practice Based on a Subgroup Analysis of the AMBORA Trial.
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- Journal of Clinical Medicine, 2022, v. 11, n. 15, p. 4558, doi. 10.3390/jcm11154558
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- Article
Comprehensibility of Contraindications in German, UK and US Summaries of Product Characteristics/Prescribing Information—A Comparative Qualitative and Quantitative Analysis.
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- Journal of Clinical Medicine, 2022, v. 11, n. 14, p. 4167, doi. 10.3390/jcm11144167
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- Article
Inconsistencies and Ambiguities in Liver-Disease-Related Contraindications—A Systematic Analysis of SmPCs/PI of Major Drug Markets.
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- Journal of Clinical Medicine, 2022, v. 11, n. 7, p. 1933, doi. 10.3390/jcm11071933
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- Article
Sympathetic Activation Enhances QT Prolongation by Quinidine.
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- Journal of Cardiovascular Electrophysiology, 2001, v. 12, n. 1, p. 9, doi. 10.1046/j.1540-8167.2001.00009.x
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- Article
Inconsistencies of absolute drug–drug contraindication reports: Analysis of Summaries of Product Characteristics of commonly prescribed drugs.
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- British Journal of Clinical Pharmacology, 2023, v. 89, n. 8, p. 2552, doi. 10.1111/bcp.15730
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- Article
Use of medication data alone to identify diagnoses and related contraindications: Application of algorithms to close a common documentation gap.
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- British Journal of Clinical Pharmacology, 2022, v. 88, n. 12, p. 5399, doi. 10.1111/bcp.15469
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- Article
The CredibleMeds<sup>®</sup> list: Usage of QT interval prolonging drugs in Germany and discordances with prescribing information.
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- British Journal of Clinical Pharmacology, 2022, v. 88, n. 1, p. 226, doi. 10.1111/bcp.14951
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- Article
Effects of single green tea ingestion on pharmacokinetics of nadolol in healthy volunteers.
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- British Journal of Clinical Pharmacology, 2020, v. 86, n. 11, p. 2314, doi. 10.1111/bcp.14315
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- Article
Cold Atmospheric Plasma Triggers Apoptosis via the Unfolded Protein Response in Melanoma Cells.
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- Cancers, 2023, v. 15, n. 4, p. 1064, doi. 10.3390/cancers15041064
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- Article
An Easily Expandable Multi-Drug LC-MS Assay for the Simultaneous Quantification of 57 Oral Antitumor Drugs in Human Plasma.
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- Cancers, 2021, v. 13, n. 24, p. 6329, doi. 10.3390/cancers13246329
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- Article
Characterisation of (R/S)-propafenone and its metabolites as substrates and inhibitors of P-glycoprotein.
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- Naunyn-Schmiedeberg's Archives of Pharmacology, 2005, v. 371, n. 3, p. 195, doi. 10.1007/s00210-005-1025-y
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- Article
Characterisation of cerivastatin as a P-glycoprotein substrate: studies in P-glycoprotein-expressing cell monolayers and mdr1a/b knock-out mice.
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- Naunyn-Schmiedeberg's Archives of Pharmacology, 2004, v. 370, n. 2, p. 124
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- Article
Pharmacokinetics of intravenous etoposide in patients with breast cancer: influence of dose escalation and cyclophosphamide and doxorubicin coadministration.
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- Naunyn-Schmiedeberg's Archives of Pharmacology, 2002, v. 366, n. 3, p. 218, doi. 10.1007/s00210-002-0594-2
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- Article
Interaction of omeprazole, lansoprazole and pantoprazole with P-glycoprotein.
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- Naunyn-Schmiedeberg's Archives of Pharmacology, 2001, v. 364, n. 6, p. 551, doi. 10.1007/s00210-001-0489-7
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- Article
P-glycoprotein-mediated transport of digitoxin, α-methyldigoxin and β-acetyldigoxin.
- Published in:
- Naunyn-Schmiedeberg's Archives of Pharmacology, 2001, v. 363, n. 3, p. 337, doi. 10.1007/s002100000354
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- Publication type:
- Article
Vectorial transport of the arginine derivatives asymmetric dimethylarginine (ADMA) and l-homoarginine by OATP4C1 and P-glycoprotein studied in double-transfected MDCK cells.
- Published in:
- Amino Acids, 2020, v. 52, n. 6/7, p. 975, doi. 10.1007/s00726-020-02867-8
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- Article
Establishment of reference values for the lysine acetylation marker N<sup>ɛ</sup>-acetyllysine in small volume human plasma samples by a multi-target LC–MS/MS method.
- Published in:
- Amino Acids, 2019, v. 51, n. 9, p. 1259, doi. 10.1007/s00726-019-02765-8
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- Article
New Oral Anti-Cancer Drugs and Medication Safety.
- Published in:
- Deutsches Ärzteblatt International, 2019, v. 116, n. 46, p. 775, doi. 10.3238/arztebl.2019.0775
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- Article
Implementation of Warnings From Dear Doctor Letters (Rote-Hand-Briefe).
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- Deutsches Ärzteblatt International, 2014, v. 111, n. 15, p. 255, doi. 10.3238/arztebl.2014.0255
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- Article
Pseudo‐Worsening of Kidney Function Due to Inhibition of Renal Creatinine Secretion: Quality of Information Provided in Prescribing Information/SmPC.
- Published in:
- Clinical Pharmacology & Therapeutics, 2024, v. 116, n. 5, p. 1259, doi. 10.1002/cpt.3374
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- Article
From the Randomized AMBORA Trial to Clinical Practice: Comparison of Medication Errors in Oral Antitumor Therapy.
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- Clinical Pharmacology & Therapeutics, 2024, v. 116, n. 1, p. 194, doi. 10.1002/cpt.3266
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- Article
A Metabolomic Analysis of Sensitivity and Specificity of 23 Previously Proposed Biomarkers for Renal Transporter‐Mediated Drug‐Drug Interactions.
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- Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 5, p. 1058, doi. 10.1002/cpt.3017
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- Article
N<sup>1</sup>‐Methylnicotinamide as Biomarker for MATE‐Mediated Renal Drug–Drug Interactions: Impact of Cimetidine, Rifampin, Verapamil, and Probenecid.
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- Clinical Pharmacology & Therapeutics, 2023, v. 113, n. 5, p. 1070, doi. 10.1002/cpt.2849
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- Article
Development in Prescriptions of Contraindicated and Potentially Harmful QT Interval–Prolonging Drugs in a Large Geriatric Inpatient Cohort From 2011 to 2021.
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- Clinical Pharmacology & Therapeutics, 2023, v. 113, n. 2, p. 435, doi. 10.1002/cpt.2813
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- Article
Exposure of Fexofenadine, but Not Pseudoephedrine, Is Markedly Decreased by Green Tea Extract in Healthy Volunteers.
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- Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 3, p. 627, doi. 10.1002/cpt.2682
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- Article