Works matching AU Froguel P

Results: 100

Mapping NIDDM susceptibility loci in French families: studies with markers in the region of NIDDM1 on chromosome 2q.

Published in:

1997

By:

Hani EH;
Hager J;
Philippi A;
Demenais F;
Froguel P;
Vionnet N;
Hani, E H;
Hager, J;
Philippi, A;
Demenais, F;
Froguel, P;
Vionnet, N

Publication type:

journal article

Diagnostic heterogeneity of diabetes in lean young adults: classification based on immunological and genetic parameters.

Published in:

1997

By:

Dussoix P;
Vaxillaire M;
Iynedjian PB;
Tiercy J;
Ruiz J;
Spinas GA;
Berger W;
Zahnd G;
Froguel P;
Philippe J;
Dussoix, P;
Vaxillaire, M;
Iynedjian, P B;
Tiercy, J M;
Ruiz, J;
Spinas, G A;
Berger, W;
Zahnd, G;
Froguel, P;
Philippe, J

Publication type:

journal article

Missense mutations in the TGM2 gene encoding transglutaminase 2 are found in patients with early-onset type 2 diabetes.

Published in:

Human Mutation, 2007, v. 28, n. 11, p. 1150, doi. 10.1002/humu.9511

By:

Porzio, O.;
Massa, O.;
Cunsolo, V.;
Colombo, C.;
Malaponti, M.;
Bertuzzi, F.;
Hansen, T.;
Johansen, A.;
Pedersen, O.;
Meschi, F.;
Terrinoni, A.;
Melino, G.;
Federici, M.;
Decarlo, N.;
Menicagli, M.;
Campani, D.;
Marchetti, P.;
Ferdaoussi, M.;
Froguel, P.;
Federici, G.

Publication type:

Article

Transmission of Type 2 diabetes to sons and daughters: the D.E.S.I.R. cohort.

Published in:

Diabetic Medicine, 2017, v. 34, n. 11, p. 1615, doi. 10.1111/dme.13446

By:

Balkau, B.;
Roussel, R.;
Wagner, S.;
Tichet, J.;
Froguel, P.;
Fagherazzi, G.;
Bonnet, F.

Publication type:

Article

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase.

Published in:

Nature Medicine, 2002, v. 8, n. 11, p. 1288, doi. 10.1038/nm788

By:

Yamauchi, T.;
Kamon, J.;
Minokoshi, Y.;
Ito, Y.;
Waki, H.;
Uchida, S.;
Yamashita, S.;
Noda, M.;
Kita, S.;
Ueki, K.;
Eto, K.;
Akanuma, Y.;
Froguel, P.;
Foufelle, F.;
Ferre, P.;
Carling, D.;
Kimura, S.;
Nagai, R.;
Kahn, B.B.;
Kadowaki, T.

Publication type:

Article

Mutation screening of the urocortin gene: identification of new single nucleotide polymorphisms and association studies with obesity in French Caucasians.

Published in:

2002

By:

Delplanque, J;
Vasseur, F;
Durand, E;
Abderrahmani, A;
Dina, C;
Waeber, G;
Guy-Grand, B;
Clement, K;
Weill, J;
Boutin, P;
Froguel, P

Publication type:

journal article

Human genes involved in copy number variation: mechanisms of origin, functional effects and implications for disease.

Published in:

Cytogenetic & Genome Research, 2009, v. 123, n. 1-4, p. 17, doi. 10.1159/000184688

By:

de Smith, A. J.;
Walters, R. G.;
Froguel, P.;
Blakemore, A. I.

Publication type:

Article

Dissection of an inverted X(p21.3q27.1) chromosome associated with mental retardation.

Published in:

Cytogenetic & Genome Research, 2003, v. 101, n. 2, p. 124, doi. 10.1159/000074167

By:

Leprêtre, F.;
Delannoy, V.;
Froguel, P.;
Vasseur, F.;
Montepellier, C.

Publication type:

Article

Multiple functional polymorphisms in the G6PC2 gene contribute to the association with higher fasting plasma glucose levels.

Published in:

Diabetologia, 2013, v. 56, n. 6, p. 1306, doi. 10.1007/s00125-013-2875-3

By:

Baerenwald, D.;
Bonnefond, A.;
Bouatia-Naji, N.;
Flemming, B.;
Umunakwe, O.;
Oeser, J.;
Pound, L.;
Conley, N.;
Cauchi, S.;
Lobbens, S.;
Eury, E.;
Balkau, B.;
Lantieri, O.;
Dadi, P.;
Jacobson, D.;
Froguel, P.;
O'Brien, R.

Publication type:

Article

Reassessment of the putative role of BLK-p.A71T loss-of-function mutation in MODY and type 2 diabetes.

Published in:

Diabetologia, 2013, v. 56, n. 3, p. 492, doi. 10.1007/s00125-012-2794-8

By:

Bonnefond, A.;
Yengo, L.;
Philippe, J.;
Dechaume, A.;
Ezzidi, I.;
Vaillant, E.;
Gjesing, A.;
Andersson, E.;
Czernichow, S.;
Hercberg, S.;
Hadjadj, S.;
Charpentier, G.;
Lantieri, O.;
Balkau, B.;
Marre, M.;
Pedersen, O.;
Hansen, T.;
Froguel, P.;
Vaxillaire, M.

Publication type:

Article

GATA6 inactivating mutations are associated with heart defects and, inconsistently, with pancreatic agenesis and diabetes.

Published in:

2012

By:

Bonnefond, A.;
Sand, O.;
Guerin, B.;
Durand, E.;
Graeve, F.;
Huyvaert, M.;
Rachdi, L.;
Kerr-Conte, J.;
Pattou, F.;
Vaxillaire, M.;
Polak, M.;
Scharfmann, R.;
Czernichow, P.;
Froguel, P.

Publication type:

Letter

TCF7L2 rs7903146 impairs islet function and morphology in non-diabetic individuals.

Published in:

Diabetologia, 2012, v. 55, n. 10, p. 2677, doi. 10.1007/s00125-012-2660-8

By:

Bacquer, O.;
Kerr-Conte, J.;
Gargani, S.;
Delalleau, N.;
Huyvaert, M.;
Gmyr, V.;
Froguel, P.;
Neve, B.;
Pattou, F.

Publication type:

Article

Mutations in G6PC2 do not contribute to monogenic forms of early infancy diabetes and beta cell dysfunction.

Published in:

2009

By:

Bonnefond, A.;
Bouatia-Naji, N.;
Simon, A.;
Saint-Martin, C.;
Dechaume, A.;
Lonlay, P.;
Polak, M.;
Bellanné-Chantelot, C.;
Froguel, P.;
Vaxillaire, M.

Publication type:

Letter

Strong association of common variants in the CDKN2A/CDKN2B region with type 2 diabetes in French Europids.

Published in:

Diabetologia, 2008, v. 51, n. 5, p. 821, doi. 10.1007/s00125-008-0973-4

By:

Duesing, K.;
Fatemifar, G.;
Charpentier, G.;
Marre, M.;
Tichet, J.;
Hercberg, S.;
Balkau, B.;
Froguel, P.;
Gibson, F.

Publication type:

Article

Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations.

Published in:

2008

By:

Franks, P.;
Rolandsson, O.;
Debenham, S.;
Fawcett, K.;
Payne, F.;
Dina, C.;
Froguel, P.;
Mohlke, K.;
Willer, C.;
Olsson, T.;
Wareham, N.;
Hallmans, G.;
Barroso, I.;
Sandhu, M.

Publication type:

Correction Notice

Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations.

Published in:

Diabetologia, 2008, v. 51, n. 3, p. 458, doi. 10.1007/s00125-007-0887-6

By:

Franks, P.;
Rolandsson, O.;
Debenham, S.;
Fawcett, K.;
Payne, F.;
Dina, C.;
Froguel, P.;
Mohlke, K.;
Willer, C.;
Olsson, T.;
Wareham, N.;
Hallmans, G.;
Barroso, I.;
Sandhu, M.

Publication type:

Article

Evaluating the association of common LMNA variants with type 2 diabetes and quantitative metabolic phenotypes in French Europids.

Published in:

Diabetologia, 2008, v. 51, n. 1, p. 76, doi. 10.1007/s00125-007-0857-z

By:

Duesing, K.;
Charpentier, G.;
Marre, M.;
Tichet, J.;
Hercberg, S.;
Froguel, P.;
Gibson, F.

Publication type:

Article

Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population.

Published in:

Diabetologia, 2007, v. 50, n. 12, p. 2461, doi. 10.1007/s00125-007-0827-5

By:

Horikoshi, M.;
Hara, K.;
Ito, C.;
Shojima, N.;
Nagai, R.;
Ueki, K.;
Froguel, P.;
Kadowaki, T.

Publication type:

Article

ENPP1 K121Q polymorphism and obesity, hyperglycaemia and type 2 diabetes in the prospective DESIR Study.

Published in:

Diabetologia, 2007, v. 50, n. 10, p. 2090, doi. 10.1007/s00125-007-0787-9

By:

Meyre, D.;
Bouatia-Naji, N.;
Vatin, V.;
Veslot, J.;
Samson, C.;
Tichet, J.;
Marre, M.;
Balkau, B.;
Froguel, P.

Publication type:

Article

A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population.

Published in:

Diabetologia, 2007, v. 50, n. 4, p. 747, doi. 10.1007/s00125-006-0588-6

By:

Horikoshi, M.;
Hara, K.;
Ito, C.;
Nagai, R.;
Froguel, P.;
Kadowaki, T.

Publication type:

Article

Single nucleotide polymorphisms in the neuropeptide Y2 receptor ( NPY2R) gene and association with severe obesity in French white subjects.

Published in:

Diabetologia, 2007, v. 50, n. 3, p. 574, doi. 10.1007/s00125-006-0555-2

By:

Siddiq, A.;
Gueorguiev, M.;
Samson, C.;
Hercberg, S.;
Heude, B.;
Levy-Marchal, C.;
Jouret, B.;
Weill, J.;
Meyre, D.;
Walley, A.;
Froguel, P.

Publication type:

Article

No major contribution of TCF7L2 sequence variants to maturity onset of diabetes of the young (MODY) or neonatal diabetes mellitus in French white subjects.

Published in:

2007

By:

Cauchi, S.;
Vaxillaire, M.;
Choquet, H.;
Durand, E.;
Duval, A.;
Polak, M.;
Froguel, P.

Publication type:

Letter

Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes.

Published in:

Diabetologia, 2005, v. 48, n. 7, p. 1307, doi. 10.1007/s00125-005-1806-3

By:

Hara, K.;
Horikoshi, M.;
Kitazato, H.;
Yamauchi, T.;
Ito, C.;
Noda, M.;
Ohashi, J.;
Froguel, P.;
Tokunaga, K.;
Nagai, R.;
Kadowaki, T.

Publication type:

Article

Hypoadiponectinaemia and high risk of type 2 diabetes are associated with adiponectin-encoding ( ACDC) gene promoter variants in morbid obesity: evidence for a role of ACDC in diabesity.

Published in:

Diabetologia, 2005, v. 48, n. 5, p. 892, doi. 10.1007/s00125-005-1729-z

By:

Vasseur, F.;
Helbecque, N.;
Lobbens, S.;
Vasseur-Delannoy, V.;
Dina, C.;
Clément, K.;
Boutin, P.;
Kadowaki, T.;
Scherer, P.E.;
Froguel, P.

Publication type:

Article

Effect of common polymorphisms in theHNF4apromoter on susceptibility to type 2 diabetes in the French Caucasian population.

Published in:

Diabetologia, 2005, v. 48, n. 3, p. 440, doi. 10.1007/s00125-004-1665-3

By:

Vaxillaire, M.;
Dina, C.;
Lobbens, S.;
Dechaume, A.;
Vasseur-Delannoy, V.;
Helbecque, N.;
Charpentier, G.;
Froguel, P.

Publication type:

Article

Single nucleotide polymorphisms of protein tyrosine phosphatase 1B gene are associated with obesity in morbidly obese French subjects PTP 1B SNPs and obesity.

Published in:

Diabetologia, 2004, v. 47, n. 7, p. 1278, doi. 10.1007/s00125-004-1432-5

By:

Kipfer-Coudreau, S.;
Eberlé, D.;
Sahbatou, M.;
Bonhomme, A.;
Guy-Grand, B.;
Froguel, P.;
Galan, P.;
Basdevant, A.;
Clément, K.

Publication type:

Article

PAI-1 polymorphisms modulate phenotypes associated with the metabolic syndrome in obese and diabetic Caucasian population C. Lopes et al.: PAI-1 polymorphisms modulate metabolic syndrome.

Published in:

Diabetologia, 2003, v. 46, n. 9, p. 1284, doi. 10.1007/s00125-003-1170-0

By:

Lopes, C.;
Dina, C.;
Durand, E.;
Froguel, P.

Publication type:

Article

Mutations in the glucokinase regulatory protein gene in 2p23 in obese French caucasians M. Veiga-da-Cunha et al.: Mutation in glucokinase regulatory protein.

Published in:

Diabetologia, 2003, v. 46, n. 5, p. 704, doi. 10.1007/s00125-003-1083-y

By:

Veiga-da-Cunha, M.;
Delplanque, J.;
Gillain, A.;
Bonthron, D. T.;
Boutin, P.;
Van Schaftingen, E.;
Froguel, P.

Publication type:

Article

Does the -11377 promoter variant of APM1 gene contribute to the genetic risk for Type 2 diabetes mellitus in Japanese families?

Published in:

Diabetologia, 2003, v. 46, n. 3, p. 443, doi. 10.1007/s00125-003-1050-7

By:

Populaire, C.;
Mori, Y.;
Dina, C.;
Vasseur, F.;
Vaxillaire, M.;
Kadowaki, T.;
Froguel, P.

Publication type:

Article

Rare variants identified in the HNF-4α β-cell-specific promoter and alternative exon 1 lack biological significance in maturity onset diabetes of the young and young onset Type II diabetes S.M.S. Mitchell et al.: HNF-4α P2 variation and diabetes susceptibility

Published in:

Diabetologia, 2002, v. 45, n. 9, p. 1344, doi. 10.1007/s00125-002-0913-7

By:

Mitchell, S.;
Vaxillaire, M.;
Thomas, H.;
Parrizas, M.;
Benmezroua, Y.;
Costa, A.;
Hansen, T.;
Owen, K.;
Tuomi, T.;
Pirie, F.;
Ryffel, G.;
Ferrer, J.;
Froguel, P.;
Hattersley, A.;
Frayling, T.

Publication type:

Article

The genetic abnormality in the beta cell determines the response to an oral glucose load.

Published in:

Diabetologia, 2002, v. 45, n. 3, p. 427, doi. 10.1007/s00125-001-0770-9

By:

Stride, A.;
Vaxillaire, M.;
Tuomi, T.;
Barbetti, F.;
Njølstad, P. R.;
Hansen, T.;
Costa, A.;
Conget, I.;
Pedersen, O.;
Søvik, O.;
Lorini, R.;
Groop, L.;
Froguel, P.;
Hattersley, A. T.

Publication type:

Article

Glucokinase gene mutations are not a common cause of permanent neonatal diabetes in France.

Published in:

Diabetologia, 2002, v. 45, n. 3, p. 454, doi. 10.1007/s00125-001-0741-1

By:

Vaxillaire, M.;
Samson, C.;
Cave, H.;
Metz, C.;
Froguel, P.;
Polak, M.

Publication type:

Article

Routine mutation screening of HNF-1α and GCK genes in MODY diagnosis: How effective are the techniques of DHPLC and direct sequencing used in combination?

Published in:

Diabetologia, 2001, v. 44, n. 6, p. 775, doi. 10.1007/s001250051687

By:

Boutin, P.;
Vasseur, F.;
Samson, C.;
Wahl, C.;
Froguel, P.

Publication type:

Article

No evidence for diabetes-associated mutations of PEK/EIF2AK3 gene in French patients with early-onset Type II diabetes.

Published in:

Diabetologia, 2001, v. 44, n. 6, p. 786

By:

Vaxillaire, M.;
Benmezroua, Y.;
Durand, E.;
Vasseur, F.;
Froguel, P.

Publication type:

Article

The authors' reply:.

Published in:

Diabetologia, 2001, v. 44, n. 4, p. 517

By:

Velho, G.;
Hattersley, A. T.;
Froguel, P.

Publication type:

Article

Genetic and environmental nature of the insulin resistance syndrome in Indo-Mauritian subjects with premature coronary heart disease: contribution of β3-adrenoreceptor gene polymorphism and beta blockers on triglyceride and HDL concentrations.

Published in:

Diabetologia, 2001, v. 44, n. 1, p. 115, doi. 10.1007/s001250051588

By:

Manraj, M.;
Francke, S.;
Hébé, A.;
Ramjuttun, U. S.;
Froguel, P.

Publication type:

Article

Linkage and association studies between the proopiomelanocortin (POMC) gene and obesity in caucasian families.

Published in:

Diabetologia, 2000, v. 43, n. 12, p. 1554, doi. 10.1007/s001250051568

By:

Delplanque, J.;
Barat-Houari, M.;
Dina, C.;
Gallina, P.;
Clément, K.;
Guy-Grand, B.;
Vasseur, F.;
Boutin, P.;
Froguel, P.

Publication type:

Article

An uncoupling protein 3 gene polymorphism associated with a lower risk of developing Type II diabetes and with atherogenic lipid profile in a French cohort.

Published in:

Diabetologia, 2000, v. 43, n. 11, p. 1424, doi. 10.1007/s001250051549

By:

Meirhaeghe, A.;
Amouyel, P.;
Helbecque, N.;
Cottel, D.;
Otabe, S.;
Froguel, P.;
Vasseur, F.

Publication type:

Article

Maternal diabetes alters birth weight in glucokinase-deficient (MODY2) kindred but has no influence on adult weight, height, insulin secretion or insulin sensitivity.

Published in:

Diabetologia, 2000, v. 43, n. 8, p. 1060, doi. 10.1007/s001250051490

By:

Velho, G.;
Hattersley, A. T.;
Froguel, P.

Publication type:

Article

A genetic variation in the 5 ′ flanking region of the UCP3 gene is associated with body mass index in humans in interaction with physical activity.

Published in:

Diabetologia, 2000, v. 43, n. 2, p. 245, doi. 10.1007/s001250050037

By:

Otabe, S.;
Clement, K.;
Dina, C.;
Pelloux, V.;
Guy-Grand, B.;
Froguel, P.;
Vasseur, F.

Publication type:

Article

beta-cell genes and diabetes: quantitative and qualitative differences in the pathophysiology of hepatic nuclear factor-1alpha and glucokinase mutations.

Published in:

2001

By:

Pearson, Ewan R.;
Velho, Gilberto;
Clark, Penny;
Stride, Amanda;
Shepherd, Maggie;
Frayling, Timothy M.;
Bulman, Michael P.;
Ellard, Sian;
Froguel, Phillipe;
Hattersley, Andrew T.;
Pearson, E R;
Velho, G;
Clark, P;
Stride, A;
Shepherd, M;
Frayling, T M;
Bulman, M P;
Ellard, S;
Froguel, P;
Hattersley, A T

Publication type:

journal article

Promoter polymorphism T(-107)C of the paraoxonase PON1 gene is a risk factor for coronary heart disease in type 2 diabetic patients.

Published in:

2000

By:

James, Richard W.;
Leviev, Ilia;
Ruiz, Juan;
Passa, Philippe;
Froguel, Philippe;
Garin, Marie-Claude Blatter;
James, R W;
Leviev, I;
Ruiz, J;
Passa, P;
Froguel, P;
Garin, M C

Publication type:

journal article

Soluble leptin receptor in serum of subjects with complete resistance to leptin: relation to fat mass.

Published in:

2000

By:

Lahlou, Najiba;
Clement, Karine;
Carel, Jean-Claude;
Vaisse, Christian;
Lotton, Chantal;
Le Bihan, Yvette;
Basdevant, Arnaud;
Lebouc, Yves;
Froguel, Philippe;
Roger, Marc;
Guy-Grand, Bernard;
Lahlou, N;
Clement, K;
Carel, J C;
Vaisse, C;
Lotton, C;
Le Bihan, Y;
Basdevant, A;
Lebouc, Y;
Froguel, P

Publication type:

journal article

Genetic variation in the hepatocyte nuclear factor-3beta gene (HNF3B) does not contribute to maturity-onset diabetes of the young in French Caucasians.

Published in:

2000

By:

Abderrahmani, A;
Chèvre, J C;
Otabe, S;
Chikri, M;
Hani, E H;
Vaxillaire, M;
Hinokio, Y;
Horikawa, Y;
Bell, G I;
Froguel, P

Publication type:

journal article

A sib-pair analysis study of 15 candidate genes in French families with morbid obesity: indication for linkage with islet 1 locus on chromosome 5q.

Published in:

1999

By:

Clément, K;
Dina, C;
Basdevant, A;
Chastang, N;
Pelloux, V;
Lahlou, N;
Berlan, M;
Langin, D;
Guy-Grand, B;
Froguel, P

Publication type:

journal article

No association between the Friedreich's ataxia gene and NIDDM in the French population.

Published in:

1998

By:

Dupont, Sophie;
Dubois, Daniele;
Vionnet, Nathalie;
Boitard, Christian;
Caillat-Zucman, Sophie;
Timsit, Jose;
Froguel, Philippe;
Dupont, S;
Dubois, D;
Vionnet, N;
Boitard, C;
Caillat-Zucman, S;
Timsit, J;
Froguel, P

Publication type:

journal article

Glucose utilization and production in patients with maturity-onset diabetes of the young caused by a mutation of the hepatocyte nuclear factor-1alpha gene.

Published in:

1998

By:

Surmely, Jean-Francois;
Guenat, Eliane;
Philippe, Jacques;
Dussoix, Philippe;
Schneiter, Philippe;
Temler, Evelyne;
Vaxillaire, Martine;
Froguel, Philippe;
Jequier, Eric;
Tappy, Luc;
Surmely, J F;
Guenat, E;
Philippe, J;
Dussoix, P;
Schneiter, P;
Temler, E;
Vaxillaire, M;
Froguel, P;
Jéquier, E;
Tappy, L

Publication type:

journal article

Insulin promoter factor 1 gene is not a major cause of maturity-onset diabetes of the young in French Caucasians.

Published in:

1998

By:

Chèvre, J C;
Hani, E H;
Stoffers, D A;
Habener, J F;
Froguel, P

Publication type:

journal article

An automated fluorescent single-strand conformation polymorphism technique for screening mutations in the hepatocyte nuclear factor-1alpha gene (maturity-onset diabetes of the young).

Published in:

1997

By:

Boutin, Philippe;
Chèvre, Jean Claude;
Haiti, El Habib;
Gomis, Ramon;
Pardini, Victor C.;
Guillausseau, Pierre-Jean;
Vaxillaire, Martine;
Velho, Gilberto;
Froguel, Philippe;
Boutin, P;
Chèvre, J C;
Hani, E H;
Gomis, R;
Pardini, V C;
Guillausseau, P J;
Vaxillaire, M;
Velho, G;
Froguel, P

Publication type:

journal article

Genetics of NIDDM in France: studies with 19 candidate genes in affected sib pairs.

Published in:

1997

By:

Vionnet, N;
Hani, E H;
Lesage, S;
Philippi, A;
Hager, J;
Varret, M;
Stoffel, M;
Tanizawa, Y;
Chiu, K C;
Glaser, B;
Permutt, M A;
Passa, P;
Demenais, F;
Froguel, P

Publication type:

journal article