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Establishment of an a priori protocol for the implementation and interpretation of an in‐vitro testing battery for the assessment of developmental neurotoxicity.
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- EFSA Supporting Publications, 2020, v. 17, n. 10, p. 1, doi. 10.2903/sp.efsa.2020.EN-1938
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Cockayne Syndrome Patient iPSC-Derived Brain Organoids and Neurospheres Show Early Transcriptional Dysregulation of Biological Processes Associated with Brain Development and Metabolism.
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- Cells (2073-4409), 2024, v. 13, n. 7, p. 591, doi. 10.3390/cells13070591
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- Article
Molecular and Functional Characterization of Different BrainSphere Models for Use in Neurotoxicity Testing on Microelectrode Arrays.
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- Cells (2073-4409), 2023, v. 12, n. 9, p. 1270, doi. 10.3390/cells12091270
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Different Calculation Strategies Are Congruent in Determining Chemotherapy Resistance of Brain Tumors In Vitro.
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- Cells (2073-4409), 2020, v. 9, n. 12, p. 2689, doi. 10.3390/cells9122689
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Reliable identification and quantification of neural cells in microscopic images of neurospheres.
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- Cytometry. Part A, 2022, v. 101, n. 5, p. 411, doi. 10.1002/cyto.a.24514
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- Article
Nitric oxide stimulates human neural progenitor cell migration via cGMP-mediated signal transduction.
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- Cellular & Molecular Life Sciences, 2011, v. 68, n. 12, p. 2089, doi. 10.1007/s00018-010-0554-9
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- Article
Application of the adverse outcome pathway concept for investigating developmental neurotoxicity potential of Chinese herbal medicines by using human neural progenitor cells in vitro.
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- Cell Biology & Toxicology, 2023, v. 39, n. 1, p. 319, doi. 10.1007/s10565-022-09730-4
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- Article
Role of the aryl hydrocarbon receptor in tobacco smoke extract-induced matrix metalloproteinase-1 expression.
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- Experimental Dermatology, 2013, v. 22, n. 5, p. 349, doi. 10.1111/exd.12148
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- Article
Xenobiotic metabolism capacities of human skin in comparison with a 3D epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: activating enzymes (Phase I).
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- Experimental Dermatology, 2012, v. 21, n. 5, p. 358, doi. 10.1111/j.1600-0625.2012.01486.x
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- Article
Xenobiotic metabolism capacities of human skin in comparison with a 3D-epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: phase II enzymes.
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- Experimental Dermatology, 2012, v. 21, n. 5, p. 364, doi. 10.1111/j.1600-0625.2012.01478.x
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- Article
Fibroblast origin shapes tissue homeostasis, epidermal differentiation, and drug uptake.
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- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-39770-6
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- Article
The Human Induced Pluripotent Stem Cell Test as an Alternative Method for Embryotoxicity Testing.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 6, p. 3295, doi. 10.3390/ijms23063295
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- Article
The ENDpoiNTs Project: Novel Testing Strategies for Endocrine Disruptors Linked to Developmental Neurotoxicity.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 11, p. 3978, doi. 10.3390/ijms21113978
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- Article
New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project.
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- Frontiers in Toxicology, 2024, p. 01, doi. 10.3389/ftox.2024.1359507
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- Article
Comprehensive mapping of the AOP-Wiki database: identifying biological and disease gaps.
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- Frontiers in Toxicology, 2024, p. 1, doi. 10.3389/ftox.2024.1285768
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- Article
Building a developmental toxicity ontology.
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- Birth Defects Research, 2018, v. 110, n. 6, p. 502, doi. 10.1002/bdr2.1189
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- Article
Human Induced Pluripotent Stem Cell‐Derived Neural Progenitor Cells Produce Distinct Neural 3D In Vitro Models Depending on Alginate/Gellan Gum/Laminin Hydrogel Blend Properties.
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- Advanced Healthcare Materials, 2021, v. 10, n. 16, p. 1, doi. 10.1002/adhm.202100131
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- Article
Stem Cells for Next Level Toxicity Testing in the 21st Century.
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- Small, 2021, v. 17, n. 15, p. 1, doi. 10.1002/smll.202006252
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Allelic Variants of Drug Metabolizing Enzymes as Risk Factors in Psoriasis.
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- Journal of Investigative Dermatology, 2003, v. 120, n. 5, p. 765, doi. 10.1046/j.1523-1747.2003.12124.x
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- Article
The Probable Future of Toxicology -- Probabilistic Risk Assessment.
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- Altex, 2024, v. 41, n. 2, p. 273, doi. 10.14573/altex.2310301
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- Article
The Impact of Biostatistics on Hazard Characterization Using In Vitro Developmental Neurotoxicity Assays.
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- Altex, 2023, v. 40, n. 4, p. 619, doi. 10.14573/altex.2210171
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- Article
A Human iPSC-Based In Vitro Neural Network Formation Assay to Investigate Neurodevelopmental Toxicity of Pesticides.
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- Altex, 2023, v. 40, n. 3, p. 452, doi. 10.14573/altex.2206031
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Report of the 1<sup>st</sup> and 2<sup>nd</sup> Mystery of Reactive Oxygen Species Conferences.
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- Altex, 2022, v. 39, n. 2, p. 336, doi. 10.14573/altex.2203011
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- Article
Corrigendum to TBBPA Targets Converging Key Events of Human Oligodendrocyte Development Resulting in Two Novel AOPs.
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- Altex, 2022, v. 39, n. 2, p. 339, doi. 10.14573/altex.2203151
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- Article
Academic Application of Good Cell Culture Practice for Induced Pluripotent Stem Cells.
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- Altex, 2021, v. 38, n. 4, p. 595, doi. 10.14573/altex.2101221
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- Article
TBBPA Targets Converging Key Events of Human Oligodendrocyte Development Resulting in Two Novel AOPs.
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- Altex, 2021, v. 38, n. 2, p. 215, doi. 10.14573/altex.2007201
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- Article
Corrigendum to Recommendation on Test Readiness Criteria for New Approach Methods in Toxicology: Exemplified for Developmental Neurotoxicity.
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- Altex, 2019, v. 36, n. 3, p. 506, doi. 10.14573/altex.1904112
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Recommendation on Test Readiness Criteria for New Approach Methods in Toxicology: Exemplified for Developmental Neurotoxicity.
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- Altex, 2018, v. 35, n. 3, p. 306, doi. 10.14573/altex.1712081
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- Article
OECD/EFSA Workshop on Developmental Neurotoxicity (DNT): The Use of Non-Animal Test Methods for Regulatory Purposes.
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- Altex, 2017, v. 34, n. 2, p. 311, doi. 10.14573/altex.1701171
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- Article
Reference Compounds for Alternative Test Methods to Indicate Developmental Neurotoxicity (DNT) Potential of Chemicals: Example Lists and Criteria for their Selection and Use.
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- Altex, 2017, v. 34, n. 1, p. 49, doi. 10.14573/altex.1604201
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- Article
State-of-the-Art of 3D Cultures (Organs-on-a-Chip) in Safety Testing and Pathophysiology.
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- Altex, 2014, v. 31, n. 4, p. 441, doi. 10.14573/altex1406111
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- Article
State-of-the-Art of 3D Cultures (Organs-on-a-Chip) in Safety Testing and Pathophysiology.
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- Altex, 2014, p. 441, doi. 10.14573/altex1406111
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- Article
International STakeholder NETwork (ISTNET) for Creating a Developmental Neurotoxicity Testing (DNT) Roadmap for Regulatory Purposes.
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- Altex, 2014, p. 223, doi. 10.14573/altex.1402121
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- Article
Advancing the Science of Developmental Neurotoxicity (DNT): Testing for Better Safety Evaluation.
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- Altex, 2012, v. 29, n. 2, p. 202, doi. 10.14573/altex.2012.2.202
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- Article
A prevalent POLG CAG microsatellite length allele in humans and African great apes POLG MICROSATELLITE IN HUMANS AND APES.
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- Mammalian Genome, 2004, v. 15, n. 6, p. 492, doi. 10.1007/s00335-004-3049-x
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- Article
Elucidation of Xenobiotic Metabolism Pathways in Human Skin and Human Skin Models by Proteomic Profiling.
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- PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0041721
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- Article
Deficiency of the clock gene Bmal1 affects neural progenitor cell migration.
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- Brain Structure & Function, 2019, v. 224, n. 1, p. 373, doi. 10.1007/s00429-018-1775-1
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- Article
Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility.
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- Nature Genetics, 2001, v. 29, n. 3, p. 261, doi. 10.1038/ng759
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- Article
Omnisphero: a high-content image analysis (HCA) approach for phenotypic developmental neurotoxicity (DNT) screenings of organoid neurosphere cultures in vitro.
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- Archives of Toxicology, 2017, v. 91, n. 4, p. 2017, doi. 10.1007/s00204-016-1852-2
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- Article
Epigallocatechin gallate (EGCG) inhibits adhesion and migration of neural progenitor cells in vitro.
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- Archives of Toxicology, 2017, v. 91, n. 2, p. 827, doi. 10.1007/s00204-016-1709-8
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- Article
Comparative human and rat neurospheres reveal species differences in chemical effects on neurodevelopmental key events.
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- Archives of Toxicology, 2016, v. 90, n. 6, p. 1415, doi. 10.1007/s00204-015-1568-8
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- Article
Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4- d]pyrimidine (PP2).
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- Archives of Toxicology, 2015, v. 89, n. 8, p. 1329, doi. 10.1007/s00204-014-1321-8
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- Article
BDE-47 and 6-OH-BDE-47 modulate calcium homeostasis in primary fetal human neural progenitor cells via ryanodine receptor-independent mechanisms.
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- Archives of Toxicology, 2014, v. 88, n. 8, p. 1537, doi. 10.1007/s00204-014-1217-7
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- Article
Regulation of dioxin receptor function by different beta-carboline alkaloids.
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- Archives of Toxicology, 2010, v. 84, n. 8, p. 619, doi. 10.1007/s00204-010-0548-2
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- Article
Tissue distribution and function of the Aryl hydrocarbon receptor repressor (AhRR) in C57BL/6 and Aryl hydrocarbon receptor deficient mice.
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- Archives of Toxicology, 2006, v. 80, n. 4, p. 206, doi. 10.1007/s00204-005-0025-5
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- Article
BDE-99 impairs differentiation of human and mouse NPCs into the oligodendroglial lineage by species-specific modes of action.
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- Scientific Reports, 2017, p. 44861, doi. 10.1038/srep44861
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- Article
Progenitor cells derived from gene‐engineered human induced pluripotent stem cells as synthetic cancer cell alternatives for in vitro pharmacology.
- Published in:
- Biotechnology Journal, 2022, v. 17, n. 6, p. 1, doi. 10.1002/biot.202100693
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- Article
HiPSC-derived 3D neural models reveal neurodevelopmental pathomechanisms of the Cockayne Syndrome B.
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- Cellular & Molecular Life Sciences, 2024, v. 81, n. 1, p. 1, doi. 10.1007/s00018-024-05406-w
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- Article
Advancing human health risk assessment.
- Published in:
- EFSA Journal, 2019, v. 17, p. N.PAG, doi. 10.2903/j.efsa.2019.e170712
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- Article
Novel chemical hazard characterisation approaches.
- Published in:
- EFSA Journal, 2016, v. 14, p. n/a, doi. 10.2903/j.efsa.2016.s0506
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- Article