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Pharmacogenetic Testing or Therapeutic Drug Monitoring: A Quantitative Framework.
- Published in:
- Clinical Pharmacokinetics, 2024, v. 63, n. 6, p. 871, doi. 10.1007/s40262-024-01382-3
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- Publication type:
- Article
Quantitative modeling of tumor dynamics and development of drug resistance in non‐small cell lung cancer patients treated with erlotinib.
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- CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 4, p. 612, doi. 10.1002/psp4.13105
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- Publication type:
- Article
Model-Informed Precision Dosing to Reduce Vincristine-Induced Peripheral Neuropathy in Pediatric Patients: A Pharmacokinetic and Pharmacodynamic Modeling and Simulation Analysis.
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- Clinical Pharmacokinetics, 2024, v. 63, n. 2, p. 197, doi. 10.1007/s40262-023-01336-1
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- Article
Multistate modeling for survival analysis in critically ill patients treated with meropenem.
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- CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 2, p. 222, doi. 10.1002/psp4.13072
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- Publication type:
- Article
Synergy of polymyxin B and minocycline against KPC-3- and OXA-48-producing Klebsiella pneumoniae in dynamic time–kill experiments: agreement with in silico predictions.
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- Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 2, p. 391, doi. 10.1093/jac/dkad394
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- Publication type:
- Article
Model‐based assessment of neutrophil‐mediated phagocytosis and digestion of bacteria across in vitro and in vivo studies.
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- CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 12, p. 1972, doi. 10.1002/psp4.13046
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- Publication type:
- Article
A multistate modeling and simulation framework to learn dose–response of oncology drugs: Application to bintrafusp alfa in non‐small cell lung cancer.
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- CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 11, p. 1738, doi. 10.1002/psp4.12976
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- Publication type:
- Article
A model‐based approach leveraging in vitro data to support dose selection from the outset: A framework for bispecific antibodies in immuno‐oncology.
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- CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 11, p. 1804, doi. 10.1002/psp4.13065
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- Article
Assessment of ibrutinib scheduling on leukocyte, lymph node size and blood pressure dynamics in chronic lymphocytic leukemia through pharmacokinetic‐pharmacodynamic models.
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- CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 9, p. 1305, doi. 10.1002/psp4.13010
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- Publication type:
- Article
Correction: Preclinical In Vivo Data Integrated in a Modeling Network Informs a Refined Clinical Strategy for a CD3 T‑Cell Bispecific in Combination with Anti‑PD‑L1.
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- 2023
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- Publication type:
- Correction Notice
Multistate Pharmacometric Model to Define the Impact of Second‐Line Immunotherapies on the Survival Outcome of the IMpower131 Study.
- Published in:
- Clinical Pharmacology & Therapeutics, 2023, v. 113, n. 4, p. 851, doi. 10.1002/cpt.2838
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- Article
Rituximab pharmacokinetic and pharmacokinetic–pharmacodynamic evaluation based on a study in diffuse large B‐cell lymphoma: Influence of tumor size on pharmacokinetic and assessment of pharmacokinetic similarity.
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- CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 2, p. 154, doi. 10.1002/psp4.12885
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- Publication type:
- Article
Optimization of blood pressure measurement practices for pharmacodynamic analyses of tyrosine-kinase inhibitors.
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- CTS: Clinical & Translational Science, 2023, v. 16, n. 1, p. 73, doi. 10.1111/cts.13423
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- Article
Bayesian forecasting of tumor size metrics and overall survival.
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- CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 12, p. 1604, doi. 10.1002/psp4.12869
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- Publication type:
- Article
Continuous infusion of piperacillin‐tazobactam significantly improves target attainment in children with cancer and fever.
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- Cancer Reports, 2022, v. 5, n. 10, p. 1, doi. 10.1002/cnr2.1585
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- Article
Population pharmacokinetics of apramycin from first-in-human plasma and urine data to support prediction of efficacious dose.
- Published in:
- 2022
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- Publication type:
- journal article
Expert workshop summary: Advancing toward a standardized murine model to evaluate treatments for antimicrobial resistance lung infections.
- Published in:
- Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.988725
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- Article
Variability of murine bacterial pneumonia models used to evaluate antimicrobial agents.
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- Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.988728
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- Publication type:
- Article
Model-Informed Translation of In Vitro Effects of Short-, Prolonged- and Continuous-Infusion Meropenem against Pseudomonas aeruginosa to Clinical Settings.
- Published in:
- Antibiotics (2079-6382), 2022, v. 11, n. 8, p. N.PAG, doi. 10.3390/antibiotics11081036
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- Publication type:
- Article
Population Pharmacokinetics and Exposure‐Response Relationships of Astegolimab in Patients With Severe Asthma.
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- Journal of Clinical Pharmacology, 2022, v. 62, n. 7, p. 905, doi. 10.1002/jcph.2021
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- Publication type:
- Article
Population Pharmacokinetics of Flucloxacillin In Bone and Soft Tissue– Standard Dosing is Not Sufficient to Achieve Therapeutic Concentrations.
- Published in:
- Pharmaceutical Research, 2022, v. 39, n. 7, p. 1633, doi. 10.1007/s11095-022-03197-y
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- Publication type:
- Article
Large-scale WGS of carbapenem-resistant Acinetobacter baumannii isolates reveals patterns of dissemination of ST clades associated with antibiotic resistance.
- Published in:
- 2022
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- Publication type:
- journal article
Publisher Correction: Anti-cancer treatment schedule optimization based on tumor dynamics modelling incorporating evolving resistance.
- Published in:
- 2022
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- Publication type:
- Correction Notice
Anti-cancer treatment schedule optimization based on tumor dynamics modelling incorporating evolving resistance.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-08012-7
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- Publication type:
- Article
Tissue Type Differences in ABCB1 Expression and Paclitaxel Tissue Pharmacokinetics in Patients With Esophageal Cancer.
- Published in:
- Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.759146
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- Publication type:
- Article
Multistate model for pharmacometric analyses of overall survival in HER2‐negative breast cancer patients treated with docetaxel.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 10, p. 1255, doi. 10.1002/psp4.12693
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- Publication type:
- Article
Effect of Scalp Cooling on the Pharmacokinetics of Paclitaxel.
- Published in:
- Cancers, 2021, v. 13, n. 15, p. 3915, doi. 10.3390/cancers13153915
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- Article
CPT: Pharmacometrics & Systems Pharmacology – Inception, Maturation, and Future Vision.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 7, p. 649, doi. 10.1002/psp4.12680
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- Publication type:
- Article
Dr. Hartmut Derendorf, PhD, a world‐renowned expert in pharmacokinetics and pharmacometrics (1953–2020).
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 6, p. 527, doi. 10.1002/psp4.12609
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- Article
Tumor growth inhibition modeling of individual lesion dynamics and interorgan variability in HER2‐negative breast cancer patients treated with docetaxel.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 5, p. 511, doi. 10.1002/psp4.12629
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- Publication type:
- Article
Pivotal Role of Translation in Anti‐Infective Development.
- Published in:
- Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 856, doi. 10.1002/cpt.2182
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- Article
Model‐Informed Drug Development for Anti‐Infectives: State of the Art and Future.
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- Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 867, doi. 10.1002/cpt.2198
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- Article
From Therapeutic Drug Monitoring to Model‐Informed Precision Dosing for Antibiotics.
- Published in:
- Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 928, doi. 10.1002/cpt.2202
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- Publication type:
- Article
Model‐Informed Drug Development for Antimicrobials: Translational PK and PK/PD Modeling to Predict an Efficacious Human Dose for Apramycin.
- Published in:
- Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1063, doi. 10.1002/cpt.2104
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- Publication type:
- Article
Colistin Resistance Development Following Colistin-Meropenem Combination Therapy Versus Colistin Monotherapy in Patients With Infections Caused by Carbapenem-Resistant Organisms.
- Published in:
- Clinical Infectious Diseases, 2020, v. 71, n. 10, p. 2599, doi. 10.1093/cid/ciz1146
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- Article
Reply to Wilson et al.
- Published in:
- 2020
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- Publication type:
- Letter to the Editor
Model-Based Biomarker Selection for Dose Individualization of Tyrosine-Kinase Inhibitors.
- Published in:
- Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2020.00316
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- Publication type:
- Article
Tumor Time‐Course Predicts Overall Survival in Non‐Small Cell Lung Cancer Patients Treated with Atezolizumab: Dependency on Follow‐Up Time.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 2, p. 115, doi. 10.1002/psp4.12489
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- Article
Pharmacometrics and Systems Pharmacology 2030.
- Published in:
- Clinical Pharmacology & Therapeutics, 2020, v. 107, n. 1, p. 76, doi. 10.1002/cpt.1683
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- Publication type:
- Article
Erratum to: Population pharmacokinetics of piperacillin in febrile children receiving cancer chemotherapy: the impact of body weight and target on an optimal dosing regimen.
- Published in:
- 2020
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- Publication type:
- journal article
Population pharmacokinetics of piperacillin in febrile children receiving cancer chemotherapy: the impact of body weight and target on an optimal dosing regimen.
- Published in:
- 2019
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- Publication type:
- journal article
Treatment Outcomes of Colistin- and Carbapenem-resistant Acinetobacter baumannii Infections: An Exploratory Subgroup Analysis of a Randomized Clinical Trial.
- Published in:
- Clinical Infectious Diseases, 2019, v. 69, n. 5, p. 769, doi. 10.1093/cid/ciy988
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- Publication type:
- Article
Effects of cladribine tablets on heart rate, atrio‐ventricular conduction and cardiac repolarization in patients with relapsing multiple sclerosis.
- Published in:
- British Journal of Clinical Pharmacology, 2019, v. 85, n. 7, p. 1484, doi. 10.1111/bcp.13919
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- Publication type:
- Article
Piperacillin pharmacokinetics and target attainment in children with cancer and fever: Can we optimize our dosing strategy?
- Published in:
- 2019
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- Publication type:
- journal article
A non-linear mixed effect model for innate immune response: In vivo kinetics of endotoxin and its induction of the cytokines tumor necrosis factor alpha and interleukin-6.
- Published in:
- PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0211981
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- Publication type:
- Article
Association between Paclitaxel Clearance and Tumor Response in Patients with Esophageal Cancer.
- Published in:
- Cancers, 2019, v. 11, n. 2, p. 173, doi. 10.3390/cancers11020173
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- Publication type:
- Article
A PK/PD Analysis of Circulating Biomarkers and Their Relationship to Tumor Response in Atezolizumab‐Treated non‐small Cell Lung Cancer Patients.
- Published in:
- Clinical Pharmacology & Therapeutics, 2019, v. 105, n. 2, p. 486, doi. 10.1002/cpt.1198
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- Publication type:
- Article
A Whole‐Body Physiologically Based Pharmacokinetic Model for Colistin and Colistin Methanesulfonate in Rat.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2018, v. 123, n. 4, p. 407, doi. 10.1111/bcpt.13026
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- Publication type:
- Article
A Pharmacometric Analysis of Patient-Reported Outcomes in Breast Cancer Patients Through Item Response Theory.
- Published in:
- Pharmaceutical Research, 2018, v. 35, n. 6, p. 1, doi. 10.1007/s11095-018-2403-8
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- Publication type:
- Article
Correction to: Model-Based Adaptive Optimal Design (MBAOD) Improves Combination Dose Finding Designs: an Example in Oncology.
- Published in:
- AAPS Journal, 2018, v. 20, n. 3, p. 1, doi. 10.1208/s12248-018-0218-5
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- Publication type:
- Article