Works by Frecer, Vladimir

Results: 26

Virtually Designed Triclosan-Based Inhibitors of Enoyl-Acyl Carrier Protein Reductase of Mycobacterium tuberculosis and of Plasmodium falciparum.

Published in:

Molecular Informatics, 2015, v. 34, n. 5, p. 292, doi. 10.1002/minf.201400141

By:

Owono Owono, Luc C.;
Ntie‐Kang, Fidele;
Keita, Melalie;
Megnassan, Eugene;
Frecer, Vladimir;
Miertus, Stanislav

Publication type:

Article

Experimental validation of specificity of the squamous cell carcinoma antigen-immunoglobulin M (SCCA-IgM) assay in patients with cirrhosis.

Published in:

Clinical Chemistry & Laboratory Medicine, 2010, v. 48, n. 2, p. 217, doi. 10.1515/CCLM.2010.044

By:

Zuin, Jessica;
Veggiani, Gianluca;
Pengo, Paolo;
Gallotta, Andrea;
Biasiolo, Alessandra;
Tono, Natascia;
Gatta, Angelo;
Pontisso, Patrizia;
Toth, Radovan;
Cerin, Dean;
Frecer, Vladimir;
Meo, Sabrina;
Gion, Massimo;
Fassina, Giorgio;
Beneduce, Luca

Publication type:

Article

How accurate is the description of ligand–protein interactions by a hybrid QM/MM approach?

Published in:

Journal of Molecular Modeling, 2018, v. 24, n. 1, p. N.PAG, doi. 10.1007/s00894-017-3537-z

By:

Kollar, Jakub;
Frecer, Vladimir

Publication type:

Article

Virtual design of novel Plasmodium falciparum cysteine protease falcipain-2 hybrid lactone–chalcone and isatin–chalcone inhibitors probing the S2 active site pocket.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 547, doi. 10.1080/14756366.2018.1564288

By:

Allangba, Koffi N'Guessan Placide Gabin;
Keita, Mélalie;
Kre N'Guessan, Raymond;
Megnassan, Eugene;
Frecer, Vladimir;
Miertus, Stanislav

Publication type:

Article

Improved Inhibitors Targeting the Thymidylate Kinase of Multidrug-Resistant Mycobacterium tuberculosis with Favorable Pharmacokinetics.

Published in:

Life (2075-1729), 2025, v. 15, n. 2, p. 173, doi. 10.3390/life15020173

By:

Konate, Souleymane;
Allangba, Koffi N'Guessan Placide Gabin;
Fofana, Issouf;
N'Guessan, Raymond Kre;
Megnassan, Eugene;
Miertus, Stanislav;
Frecer, Vladimir

Publication type:

Article

Design of Thymidine Analogues Targeting Thymidilate Kinase of Mycobacterium tuberculosis.

Published in:

Tuberculosis Research & Treatment, 2013, p. 1, doi. 10.1155/2013/670836

By:

Owono, Luc Calvin Owono;
Keita, Melalie;
Megnassan, Eugene;
Frecer, Vladimir;
Miertus, Stanislav

Publication type:

Article

Structure-Based Design and Pharmacophore-Based Virtual Screening of Combinatorial Library of Triclosan Analogues Active against Enoyl-Acyl Carrier Protein Reductase of Plasmodium falciparum with Favourable ADME Profiles.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 8, p. 6916, doi. 10.3390/ijms24086916

By:

Bieri, Cecile;
Esmel, Akori;
Keita, Melalie;
Owono, Luc Calvin Owono;
Dali, Brice;
Megnassan, Eugene;
Miertus, Stanislav;
Frecer, Vladimir

Publication type:

Article

Structure-Based Design and in Silico Screening of Virtual Combinatorial Library of Benzamides Inhibiting 2-trans Enoyl-Acyl Carrier Protein Reductase of Mycobacterium tuberculosis with Favorable Predicted Pharmacokinetic Profiles.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 19, p. 4730, doi. 10.3390/ijms20194730

By:

Kouman, Koffi Charles;
Keita, Melalie;
Kre N'Guessan, Raymond;
Owono Owono, Luc Calvin;
Megnassan, Eugene;
Frecer, Vladimir;
Miertus, Stanislav

Publication type:

Article

Computer-Aided Design of Orally Bioavailable Pyrrolidine Carboxamide Inhibitors of Enoyl-Acyl Carrier Protein Reductase of Mycobacterium tuberculosis with Favorable Pharmacokinetic Profiles.

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 12, p. 29744, doi. 10.3390/ijms161226196

By:

Kouassi, Affiba Florance;
Kone, Mawa;
Keita, Melalie;
Esmel, Akori;
Megnassan, Eugene;
N'Guessan, Yao Thomas;
Frecer, Vladimir;
Miertus, Stanislav

Publication type:

Article

Computer-assisted combinatorial design of bicyclic thymidine analogs as inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.

Published in:

Journal of Computer-Aided Molecular Design, 2011, v. 25, n. 1, p. 31, doi. 10.1007/s10822-010-9399-4

By:

Frecer, Vladimir;
Seneci, Pierfausto;
Miertus, Stanislav

Publication type:

Article

Design, structure-based focusing and in silico screening of combinatorial library of peptidomimetic inhibitors of Dengue virus NS2B-NS3 protease.

Published in:

Journal of Computer-Aided Molecular Design, 2010, v. 24, n. 3, p. 195, doi. 10.1007/s10822-010-9326-8

By:

Frecer, Vladimir;
Miertus, Stanislav

Publication type:

Article

Epithelial cell adhesion on films mimicking surface of polymeric scaffolds of artificial urethra compared to molecular modeling of integrin binding.

Published in:

Journal of Bioactive & Compatible Polymers, 2019, v. 34, n. 3, p. 280, doi. 10.1177/0883911519843309

By:

Kollar, Jakub;
Morelli, Andrea;
Chiellini, Federica;
Miertus, Stanislav;
Bakos, Dusan;
Frecer, Vladimir

Publication type:

Article

Rational design of green fluorescent protein mutants as biosensor for bacterial endotoxin.

Published in:

Protein Engineering, 2002, v. 15, n. 6, p. 493, doi. 10.1093/protein/15.6.493

By:

Goh, Yan Y.;
Frecer, Vladimir;
Ho, Bow;
Ding, Jeak L.

Publication type:

Article

Conformational Analysis of Methyl Phenylcarbamate and its Methoxy Derivatives by MO Calculations.

Published in:

Archiv der Pharmazie, 1983, v. 316, n. 1, p. 9, doi. 10.1002/ardp.19833160105

By:

Remko, Milan;
Frecer, Vladimír;
Čižmárik, Jozef

Publication type:

Article

Ultraviolet A radiation potentiates the cytotoxic and genotoxic effects of 7 H-dibenzo[ c, g]carbazole and its methyl derivatives.

Published in:

Environmental & Molecular Mutagenesis, 2015, v. 56, n. 4, p. 388, doi. 10.1002/em.21927

By:

Sedlačková, Eva;
Bábelová, Andrea;
Kozics, Katarína;
Šelc, Michal;
Srančíková, Annamária;
Frecer, Vladimír;
Gábelová, Alena;
Menck, C.

Publication type:

Article

Development of a novel diagnostic algorithm to predict NASH in HCV-positive patients.

Published in:

International Journal of Biological Markers, 2018, v. 33, n. 2, p. 231, doi. 10.1177/1724600817753577

By:

Gallotta, Andrea;
Paneghetti, Laura;
Mrázová, Viera;
Bednárová, Adriana;
Kružlicová, Dáša;
Frecer, Vladimir;
Miertus, Stanislav;
Biasiolo, Alessandra;
Martini, Andrea;
Pontisso, Patrizia;
Fassina, Giorgio

Publication type:

Article

Utilizing N‐Hydroxylamine‐Based Active Esters for the Synthesis of Oseltamivir Amide Derivatives.

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 5, p. 1, doi. 10.1002/ejoc.202401139

By:

Zahradníková, Barbora;
Mravíková, Zuzana;
Némethová, Viktória;
Polnišerová, Petra;
Frecer, Vladimír;
Mečiarová, Mária;
Šebesta, Radovan

Publication type:

Article

Modeling the effect of 3 missense AGXT mutations on dimerization of the AGT enzyme in primary hyperoxaluria type 1.

Published in:

Journal of Nephrology (JNonline), 2010, v. 23, n. 6, p. 667

By:

Robbiano, Angela;
Frecer, Vladimir;
Miertus, Jan;
Zadro, Cristina;
Ulivi, Sheila;
Bevilacqua, Elena;
Mandrile, Giorgia;
De Marchi, Mario;
Miertus, Stanislav;
Amoroso, Antonio

Publication type:

Article

A SALL4 zinc finger missense mutation predicted to result in increased DNA binding affinity is associated with cranial midline defects and mild features of Okihiro syndrome.

Published in:

Human Genetics, 2006, v. 119, n. 1/2, p. 154, doi. 10.1007/s00439-005-0124-7

By:

Miertus, Jan;
Borozdin, Wiktor;
Frecer, Vladimir;
Tonini, Giorgio;
Bertok, Sara;
Amoroso, Antonio;
Miertus, Stanislav;
Kohlhase, Jürgen

Publication type:

Article

New potent N‐hydroxycinnamamide‐based histone deacetylase inhibitors suppress proliferation and trigger apoptosis in THP‐1 leukaemia cells.

Published in:

Archiv der Pharmazie, 2025, v. 358, n. 4, p. 1, doi. 10.1002/ardp.202400889

By:

Onuscakova, Magdalena;
Kauerova, Tereza;
Fialova, Eva;
Pizova, Hana;
Garaj, Vladimir;
Kemka, Miroslav;
Frecer, Vladimir;
Kollar, Peter;
Bobal, Pavel

Publication type:

Article

A Novel Human Tectonin Protein with Multivalent b- Propeller Folds Interacts with Ficolin and Binds Bacterial LPS.

Published in:

PLoS ONE, 2009, v. 4, n. 7, p. 1, doi. 10.1371/journal.pone.0006260

By:

Diana Hooi Ping Low;
Zhiwei Ang;
Quan Yuan;
Vladimir Frecer;
Bow Ho;
Jianzhu Chen;
Jeak Ling Ding

Publication type:

Article

Polarizable continuum model of solvation for biopolymers.

Published in:

International Journal of Quantum Chemistry, 1992, v. 42, n. 5, p. 1449, doi. 10.1002/qua.560420520

By:

Frecer, Vladimír;
Miertuš, Stanislav

Publication type:

Article

Pathogenicity of new BEST1 variants identified in Italian patients with best vitelliform macular dystrophy assessed by computational structural biology.

Published in:

2019

By:

Frecer, Vladimir;
Iarossi, Giancarlo;
Salvetti, Anna Paola;
Maltese, Paolo Enrico;
Delledonne, Giulia;
Oldani, Marta;
Staurenghi, Giovanni;
Falsini, Benedetto;
Minnella, Angelo Maria;
Ziccardi, Lucia;
Magli, Adriano;
Colombo, Leonardo;
D'Esposito, Fabiana;
Miertus, Jan;
Viola, Francesco;
Attanasio, Marcella;
Maggio, Emilia;
Bertelli, Matteo

Publication type:

journal article

Interactions of ligands with macromolecules: Rational design of specific inhibitors of aspartic protease of HIV-1.

Published in:

Macromolecular Chemistry & Physics, 2002, v. 203, n. 10-11, p. 1650, doi. 10.1002/1521-3935(200207)203:10/11<1650::AID-MACP1650>3.0.CO;2-E

By:

Frecer, Vladimir;
Miertus, Stanislav

Publication type:

Article

One step at a time.

Published in:

Virulence, 2010, v. 1, n. 1, p. 42, doi. 10.4161/viru.1.1.10229

By:

Leptihn, Sebastian;
Guo, Lin;
Frecer, Vladimir;
Ho, Bow;
Ding, Jeak Ling;
Wohland, Thorsten

Publication type:

Article

Insight into Selectivity of Peptidomimetic Inhibitors with Modified Statine Core for Plasmepsin II of Plasmodium falciparum over Human Cathepsin D.

Published in:

Chemical Biology & Drug Design, 2012, v. 79, n. 4, p. 411, doi. 10.1111/j.1747-0285.2011.01276.x

By:

Dali, Brice;
Keita, Melalie;
Megnassan, Eugene;
Frecer, Vladimir;
Miertus, Stanislav

Publication type:

Article