Works by Freccero, Mauro

Results: 32

Naphthalene diimide-naphthalimide dyads promote telomere damage by selectively targeting multimeric G-quadruplexes Open Access.

Published in:

Nucleic Acids Research, 2025, v. 53, n. 7, p. 1, doi. 10.1093/nar/gkaf301

By:

Pirota, Valentina;
Iachettini, Sara;
Platella, Chiara;
Zizza, Pasquale;
Fracchioni, Giorgia;
Di Vito, Serena;
Carachino, Alice;
Battistini, Federica;
Orozco, Modesto;
Freccero, Mauro;
Biroccio, Annamaria;
Montesarchio, Daniela;
Doria, Filippo

Publication type:

Article

Photoactivatable V‐Shaped Bifunctional Quinone Methide Precursors as a New Class of Selective G‐quadruplex Alkylating Agents.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 35, p. 1, doi. 10.1002/chem.202200734

By:

Lena, Alberto;
Benassi, Alessandra;
Stasi, Michele;
Saint‐Pierre, Christine;
Freccero, Mauro;
Gasparutto, Didier;
Bombard, Sophie;
Doria, Filippo;
Verga, Daniela

Publication type:

Article

Selective Binding and Redox-Activity on Parallel G-Quadruplexes by Pegylated Naphthalene Diimide-Copper Complexes.

Published in:

Molecules, 2021, v. 26, n. 16, p. 5025, doi. 10.3390/molecules26165025

By:

Pirota, Valentina;
Lunghi, Enrico;
Benassi, Alessandra;
Crespan, Emmanuele;
Freccero, Mauro;
Doria, Filippo

Publication type:

Article

Towards Building Blocks for Supramolecular Architectures Based on Azacryptates.

Published in:

Molecules, 2020, v. 25, n. 7, p. 1733, doi. 10.3390/molecules25071733

By:

Miljkovic, Ana;
La Cognata, Sonia;
Bergamaschi, Greta;
Freccero, Mauro;
Poggi, Antonio;
Amendola, Valeria

Publication type:

Article

Design of Disruptors of the Hsp90–Cdc37 Interface.

Published in:

Molecules, 2020, v. 25, n. 2, p. 360, doi. 10.3390/molecules25020360

By:

D'Annessa, Ilda;
Hurwitz, Naama;
Pirota, Valentina;
Beretta, Giovanni Luca;
Tinelli, Stella;
Woodford, Mark;
Freccero, Mauro;
Mollapour, Mehdi;
Zaffaroni, Nadia;
Wolfson, Haim;
Colombo, Giorgio

Publication type:

Article

Oxadiazole/Pyridine-Based Ligands: A Structural Tuning for Enhancing G-Quadruplex Binding.

Published in:

Molecules, 2018, v. 23, n. 9, p. 2162, doi. 10.3390/molecules23092162

By:

Doria, Filippo;
Pirota, Valentina;
Petenzi, Michele;
Teulade-Fichou, Marie-Paule;
Verga, Daniela;
Freccero, Mauro

Publication type:

Article

A Fragment-Based Approach for the Development of G-Quadruplex Ligands: Role of the Amidoxime Moiety.

Published in:

Molecules, 2018, v. 23, n. 8, p. 1874, doi. 10.3390/molecules23081874

By:

Eritja, Ramon;
Tassinari, Martina;
Butovskaya, Elena;
Nadai, Matteo;
Richter, Sara N.;
Lena, Alberto;
Pirota, Valentina;
Freccero, Mauro;
Doria, Filippo

Publication type:

Article

Cover Feature: The Quest for the Right Trade‐Off for an Efficient Photoclick Monitoring Reaction (ChemPhotoChem 3/2022).

Published in:

ChemPhotoChem, 2022, v. 6, n. 3, p. 1, doi. 10.1002/cptc.202200034

By:

Benassi, Alessandra;
Pirota, Valentina;
Doria, Filippo;
Freccero, Mauro

Publication type:

Article

The Quest for the Right Trade‐Off for an Efficient Photoclick Monitoring Reaction.

Published in:

ChemPhotoChem, 2022, v. 6, n. 3, p. 1, doi. 10.1002/cptc.202100204

By:

Benassi, Alessandra;
Pirota, Valentina;
Doria, Filippo;
Freccero, Mauro

Publication type:

Article

Extended Naphthalene Diimides with Donor/Acceptor Hydrogen-Bonding Properties Targeting G-Quadruplex Nucleic Acids.

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 28, p. 4824, doi. 10.1002/ejoc.201600757

By:

Doria, Filippo;
Nadai, Matteo;
Costa, Giosuè;
Sattin, Giovanna;
Gallati, Caroline;
Bergamaschi, Greta;
Moraca, Federica;
Alcaro, Stefano;
Freccero, Mauro;
Richter, Sara N.

Publication type:

Article

Naphthalene diimide‐derivatives G‐quadruplex ligands induce cell proliferation inhibition, mild telomeric dysfunction and cell cycle perturbation in U251MG glioma cells.

Published in:

FEBS Journal, 2018, v. 285, n. 20, p. 3769, doi. 10.1111/febs.14628

By:

Muoio, Daniela;
Berardinelli, Francesco;
Leone, Stefano;
Coluzzi, Elisa;
di Masi, Alessandra;
Doria, Filippo;
Freccero, Mauro;
Sgura, Antonella;
Folini, Marco;
Antoccia, Antonio

Publication type:

Article

Assessment of gene promoter G-quadruplex binding and modulation by a naphthalene diimide derivative in tumor cells.

Published in:

International Journal of Oncology, 2015, v. 46, n. 1, p. 369, doi. 10.3892/ijo.2014.2723

By:

MATTEO NADAI;
CIMINO-REALE, GRAZIELLA;
SATTIN, GIOVANNA;
DORIA, FILIPPO;
BUTOVSKAYA, ELENA;
ZAFFARONI, NADIA;
FRECCERO, MAURO;
PALUMBO, MANLIO;
RICHTER, SARA N.;
FOLINI, MARCO

Publication type:

Article

An Aggregating Amphiphilic Squaraine: A Light-up Probe That Discriminates Parallel G-Quadruplexes.

Published in:

Angewandte Chemie International Edition, 2017, v. 56, n. 26, p. 7520, doi. 10.1002/anie.201702096

By:

Grande, Vincenzo;
Doria, Filippo;
Freccero, Mauro;
Würthner, Frank

Publication type:

Article

Crystal structures of 2,4,9-trimethyl-(3ar,4c,9c,9ac)-3a,4,9,9a-tetrahydro-benzo[ƒ] isoindole-1,3-dione( endo), C15H17NO2 ( 1), and 2-methyl-(3ac,9ac)-3a,4,9,9a-tetrahydro-4r,9c-ethano-benzo[ƒ]isoindole-1, 3-dione( endo), C15H15NO2 ( 2)

Published in:

Journal of Chemical Crystallography, 2005, v. 35, n. 8, p. 641, doi. 10.1007/s10870-005-6162-0

By:

Bovio, Bruna;
Freccero, Mauro;
Sarzi-Amadè, Mirko

Publication type:

Article

An Aggregating Amphiphilic Squaraine: A Light-up Probe That Discriminates Parallel G-Quadruplexes.

Published in:

Angewandte Chemie, 2017, v. 129, n. 26, p. 7628, doi. 10.1002/ange.201702096

By:

Grande, Vincenzo;
Doria, Filippo;
Freccero, Mauro;
Würthner, Frank

Publication type:

Article

Trifunctionalized Naphthalene Diimides and Dimeric Analogues as G-Quadruplex-Targeting Anticancer Agents Selected by Affinity Chromatography.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 6, p. 1964, doi. 10.3390/ijms21061964

By:

Platella, Chiara;
Pirota, Valentina;
Musumeci, Domenica;
Rizzi, Federica;
Iachettini, Sara;
Zizza, Pasquale;
Biroccio, Annamaria;
Freccero, Mauro;
Montesarchio, Daniela;
Doria, Filippo

Publication type:

Article

Modeling the Photochemistry of the Reference Phototoxic Drug Lomefloxacin by Steady-State and Time-Resolved Experiments, and DFT and Post-HF Calculations.

Published in:

Chemistry - A European Journal, 2008, v. 14, n. 2, p. 653, doi. 10.1002/chem.200701099

By:

Freccero, Mauro;
Fasani, Elisa;
Mella, Mariella;
Manet, Ilse;
Monti, Sandra;
Albini, Angelo

Publication type:

Article

Photosensitized Oxidation of Sulfides: Discriminating between the Singlet-Oxygen Mechanism and Electron Transfer Involving Superoxide Anion or Molecular Oxygen.

Published in:

Chemistry - A European Journal, 2006, v. 12, n. 18, p. 4844, doi. 10.1002/chem.200501144

By:

Sergio M. Bonesi;
Ilse Manet;
Mauro Freccero;
Maurizio Fagnoni;
Angelo Albini

Publication type:

Article

On the interaction of an anticancer trisubstituted naphthalene diimide with G-quadruplexes of different topologies: a structural insight.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 21, p. 12380, doi. 10.1093/nar/gkaa1001

By:

Platella, Chiara;
Trajkovski, Marko;
Doria, Filippo;
Freccero, Mauro;
Plavec, Janez;
Montesarchio, Daniela

Publication type:

Article

Selective targeting of mutually exclusive DNA G-quadruplexes: HIV-1 LTR as paradigmatic model.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4627, doi. 10.1093/nar/gkaa186

By:

Tassinari, Martina;
Zuffo, Michela;
Nadai, Matteo;
Pirota, Valentina;
Sevilla Montalvo, Adriana Carolina;
Doria, Filippo;
Freccero, Mauro;
Richter, Sara N

Publication type:

Article

More is not always better: finding the right trade-off between affinity and selectivity of a G-quadruplex ligand.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 19, p. e115, doi. 10.1093/nar/gky607

By:

Zuffo, Michela;
Guédin, Aurore;
Leriche, Emma-Dune;
Doria, Filippo;
Pirota, Valentina;
Gabelica, Valérie;
Mergny, Jean-Louis;
Freccero, Mauro

Publication type:

Article

Synthesis, Binding Properties, and Differences in Cell Uptake of G-Quadruplex Ligands Based on Carbohydrate Naphthalene Diimide Conjugates.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 9, p. 2157, doi. 10.1002/chem.201604886

By:

Arévalo‐Ruiz, Matilde;
Doria, Filippo;
Belmonte‐Reche, Efres;
De Rache, Aurore;
Campos‐Salinas, Jenny;
Lucas, Ricardo;
Falomir, Eva;
Carda, Miguel;
Pérez‐Victoria, José María;
Mergny, Jean‐Louis;
Freccero, Mauro;
Morales, Juan Carlos

Publication type:

Article

Red/NIR G-Quadruplex Sensing, Harvesting Blue Light by a Coumarin-Naphthalene Diimide Dyad.

Published in:

Chemistry - A European Journal, 2015, v. 21, n. 49, p. 17596, doi. 10.1002/chem.201503020

By:

Zuffo, Michela;
Doria, Filippo;
Spalluto, Vincenzo;
Ladame, Sylvain;
Freccero, Mauro

Publication type:

Article

A Photoreactive G-Quadruplex Ligand Triggered by Green Light.

Published in:

Chemistry - A European Journal, 2015, v. 21, n. 6, p. 2330, doi. 10.1002/chem.201405215

By:

Nadai, Matteo;
Doria, Filippo;
Germani, Luca;
Richter, Sara N.;
Freccero, Mauro

Publication type:

Article

Targeting Loop Adenines in G-Quadruplex by a Selective Oxirane.

Published in:

Chemistry - A European Journal, 2013, v. 19, n. 1, p. 78, doi. 10.1002/chem.201203097

By:

Doria, Filippo;
Nadai, Matteo;
Folini, Marco;
Scalabrin, Matteo;
Germani, Luca;
Sattin, Giovanna;
Mella, Mariella;
Palumbo, Manlio;
Zaffaroni, Nadia;
Fabris, Daniele;
Freccero, Mauro;
Richter, Sara N.

Publication type:

Article

Cationic Pentaheteroaryls as Selective G-Quadruplex Ligands by Solvent-Free Microwave-Assisted Synthesis.

Published in:

Chemistry - A European Journal, 2012, v. 18, n. 45, p. 14487, doi. 10.1002/chem.201202097

By:

Petenzi, Michele;
Verga, Daniela;
Largy, Eric;
Hamon, Florian;
Doria, Filippo;
Teulade-Fichou, Marie-Paule;
Guédin, Aurore;
Mergny, Jean-Louis;
Mella, Mariella;
Freccero, Mauro

Publication type:

Article

A computational workflow for the design of irreversible inhibitors of protein kinases.

Published in:

Journal of Computer-Aided Molecular Design, 2010, v. 24, n. 3, p. 183, doi. 10.1007/s10822-010-9324-x

By:

Del Rio, Alberto;
Sgobba, Miriam;
Daniele Parenti, Marco;
Degliesposti, Gianluca;
Forestiero, Rosetta;
Percivalle, Claudia;
Conte, Pier Franco;
Freccero, Mauro;
Rastelli, Giulio

Publication type:

Article

The Binding Pocket at the Interface of Multimeric Telomere G‐quadruplexes: Myth or Reality?

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 45, p. 11707, doi. 10.1002/chem.202101486

By:

Manoli, Francesco;
Doria, Filippo;
Colombo, Giorgio;
Zambelli, Barbara;
Freccero, Mauro;
Manet, Ilse

Publication type:

Article

Dyads of G‐Quadruplex Ligands Triggering DNA Damage Response and Tumour Cell Growth Inhibition at Subnanomolar Concentration.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 47, p. 11085, doi. 10.1002/chem.201900766

By:

Doria, Filippo;
Salvati, Erica;
Pompili, Luca;
Pirota, Valentina;
D'Angelo, Carmen;
Manoli, Francesco;
Nadai, Matteo;
Richter, Sara N.;
Biroccio, Annamaria;
Manet, Ilse;
Freccero, Mauro

Publication type:

Article

The Oncogenic Signaling Pathways in BRAF-Mutant Melanoma Cells Are Modulated by Naphthalene Diimide-Like G-Quadruplex Ligands.

Published in:

Cells (2073-4409), 2019, v. 8, n. 10, p. 1274, doi. 10.3390/cells8101274

By:

Recagni, Marta;
Tassinari, Martina;
Doria, Filippo;
Cimino-Reale, Graziella;
Zaffaroni, Nadia;
Freccero, Mauro;
Folini, Marco;
Richter, Sara N.

Publication type:

Article

Core-Extended Naphthalene Diimide Dyads as Light-Up Probes with Targeted Cytotoxicity Toward Tumor Cells.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 311, doi. 10.3390/biom15020311

By:

Pirota, Valentina;
Salvati, Erica;
Risoldi, Carla;
Manoli, Francesco;
Rizzo, Angela;
Zizza, Pasquale;
Biroccio, Annamaria;
Freccero, Mauro;
Manet, Ilse;
Doria, Filippo

Publication type:

Article

Photosensitized oxygenation of some benzyl sulfides. The role of persulfoxide.

Published in:

Journal of Physical Organic Chemistry, 1999, v. 12, n. 9, p. 703, doi. 10.1002/(SICI)1099-1395(199909)12:9<703::AID-POC178>3.0.CO;2-L

By:

Bonesi, Sergio M.;
Freccero, Mauro;
Albini, Angelo

Publication type:

Article