Works by Freathy, Rachel M.

Results: 54

Challenges and solutions for diabetes early career researchers in the COVID-19 recovery: Perspectives of the Diabetes UK Innovators in Diabetes.
Published in:
Diabetic Medicine, 2022, v. 39, n. 3, p. 1, doi. 10.1111/dme.14698
By:
- Gage, Matthew C.;
- Harrington, Deirdre;
- Brierley, Gemma V.;
- Freathy, Rachel M.;
- Gabriel, Brendan M.;
- Gibson, Rachel;
- McNeilly, Alison D.;
- Meek, Claire L.;
- Roberts, Lee D.
Publication type:
Article
Association of maternal circulating 25(OH)D and calcium with birth weight: A mendelian randomisation analysis.
Published in:
2019
By:
- Thompson, William D.;
- Tyrrell, Jessica;
- Borges, Maria-Carolina;
- Beaumont, Robin N.;
- Knight, Bridget A.;
- Wood, Andrew R.;
- Ring, Susan M.;
- Hattersley, Andrew T.;
- Freathy, Rachel M.;
- Lawlor, Debbie A.
Publication type:
journal article
Intrauterine Growth and Offspring Neurodevelopmental Traits: A Mendelian Randomization Analysis of the Norwegian Mother, Father and Child Cohort Study (MoBa).
Published in:
JAMA Psychiatry, 2024, v. 81, n. 2, p. 144, doi. 10.1001/jamapsychiatry.2023.3872
By:
- D'Urso, Shannon;
- Moen, Gunn-Helen;
- Hwang, Liang-Dar;
- Hannigan, Laurie J.;
- Corfield, Elizabeth C.;
- Ask, Helga;
- Johannson, Stefan;
- Njølstad, Pål Rasmus;
- Beaumont, Robin N.;
- Freathy, Rachel M.;
- Evans, David M.;
- Havdahl, Alexandra
Publication type:
Article
The influence of transmitted and non-transmitted parental BMI-associated alleles on the risk of overweight in childhood.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-61719-3
By:
- Schnurr, Theresia M.;
- Morgen, Camilla S.;
- Borisevich, Dmitrii;
- Beaumont, Robin N.;
- Engelbrechtsen, Line;
- Ängquist, Lars;
- Have, Christian T.;
- Freathy, Rachel M.;
- Smith, George Davey;
- Nohr, Ellen A.;
- Hansen, Torben;
- Sørensen, Thorkild I. A.
Publication type:
Article
Phosphodiesterase 8B Gene Polymorphism Is Associated with Subclinical Hypothyroidism in Pregnancy.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2009, v. 94, n. 11, p. 4608, doi. 10.1210/jc.2009-1298
By:
- Shields, Beverley M.;
- Freathy, Rachel M.;
- Knight, Bridget A.;
- Hill, Anita;
- Weedon, Michael N.;
- Frayling, Timothy M.;
- Hattersley, Andrew T.;
- Vaidya, Bijay
Publication type:
Article
The Effect of Genetic Variation on the Placental Transcriptome in Humans.
Published in:
Frontiers in Genetics, 2019, p. N.PAG, doi. 10.3389/fgene.2019.00550
By:
- Kikas, Triin;
- Rull, Kristiina;
- Beaumont, Robin N.;
- Freathy, Rachel M.;
- Laan, Maris
Publication type:
Article
Adult height variants affect birth length and growth rate in children.
Published in:
Human Molecular Genetics, 2011, v. 20, n. 20, p. 4069, doi. 10.1093/hmg/ddr309
By:
- Paternoster, Lavinia;
- Howe, Laura D.;
- Tilling, Kate;
- Weedon, Michael N.;
- Freathy, Rachel M.;
- Frayling, Timothy M.;
- Kemp, John P.;
- Smith, George Davey;
- Timpson, Nicholas J.;
- Ring, Susan M.;
- Evans, David M.;
- Lawlor, Debbie A.
Publication type:
Article
A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5–CHRNA3–CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy.
Published in:
Human Molecular Genetics, 2009, v. 18, n. 15, p. 2922, doi. 10.1093/hmg/ddp216
By:
- Freathy, Rachel M.;
- Ring, Susan M.;
- Shields, Beverley;
- Galobardes, Bruna;
- Knight, Beatrice;
- Weedon, Michael N.;
- Smith, George Davey;
- Frayling, Timothy M.;
- Hattersley, Andrew T.
Publication type:
Article
Association of COMT Val(108/158)Met genotype and cigarette smoking in pregnant women.
Published in:
2011
By:
- Munafò MR;
- Freathy RM;
- Ring SM;
- St Pourcain B;
- Davey Smith G;
- Munafò, Marcus R;
- Freathy, Rachel M;
- Ring, Susan M;
- St Pourcain, Beate;
- Smith, George Davey
Publication type:
journal article
Association of COMT Val108/158Met Genotype and Cigarette Smoking in Pregnant Women.
Published in:
Nicotine & Tobacco Research, 2011, v. 13, n. 2, p. 55, doi. 10.1093/ntr/ntq209
By:
- Munafò, Marcus R.;
- Freathy, Rachel M.;
- Ring, Susan M.;
- St Pourcain, Beate;
- Davey Smith, George
Publication type:
Article
Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study: Common Genetic Variants in GCK and TCF7L2 Are Associated With Fasting and Postchallenge Glucose Levels in Pregnancy and With the New Consensus Definition of Gestational Diabetes Mellitus From the International Association of Diabetes and Pregnancy Study Groups
Published in:
Diabetes, 2010, v. 59, n. 10, p. 2682, doi. 10.2337/db10-0177
By:
- Freathy, Rachel M.;
- Hayes, M. Geoffrey;
- Urbanek, Margrit;
- Lowe, Lynn P.;
- Lee, Hoon;
- Ackerman, Christine;
- Frayling, Timothy M.;
- Cox, Nancy J.;
- Dunger, David B.;
- Dyer, Alan R.;
- Hattersley, Andrew T.;
- Metzger, Boyd E.;
- Lowe Jr., William L.
Publication type:
Article
Type 2 Diabetes Risk Alleles Are Associated With Reduced Size at Birth.
Published in:
Diabetes, 2009, v. 58, n. 6, p. 1428, doi. 10.2337/db08-1739
By:
- Freathy, Rachel M.;
- Bennett, Amanda J.;
- Ring, Susan M.;
- Shields, Beverley;
- Groves, Christopher J.;
- Timpson, Nicholas J.;
- Weedon, Michael N.;
- Zeggini, Eleftheria;
- Lindgren, Cecilia M.;
- Lango, Hana;
- Perry, John R. B.;
- Pouta, Anneli;
- Ruokonen, Aimo;
- Hyppönen, Elina;
- Power, Chris;
- Elliott, Paul;
- Strachan, David P.;
- Järvelin, Marjo-Riitta;
- Smith, George Davey;
- McCarthy, Mark I.
Publication type:
Article
Common Variation in the FTO Gene Alters Diabetes-Related Metabolic Traits to the Extent Expected Given Its Effect on BMI.
Published in:
Diabetes, 2008, v. 57, n. 5, p. 1419, doi. 10.2337/db07-1466
By:
- Freathy, Rachel M.;
- Timpson, Nicholas J.;
- Lawlor, Debbie A.;
- Pouta, Anneli;
- Ben-Shlomo, Yoav;
- Ruokonen, Aimo;
- Ebrahim, Shah;
- Shields, Beverley;
- Zeggini, Eleftheria;
- Weedon, Michael N.;
- Lindgren, Cecilia M.;
- Lango, Hana;
- Melzer, David;
- Ferrucci, Luigi;
- Paolisso, Giuseppe;
- Neville, Matthew J.;
- Karpe, Fredrik;
- Palmer, Colin N. A.;
- Morris, Andrew D.;
- Elliott, Paul
Publication type:
Article
Dissecting maternal and fetal genetic effects underlying the associations between maternal phenotypes, birth outcomes, and adult phenotypes: A mendelian-randomization and haplotype-based genetic score analysis in 10,734 mother-infant pairs.
Published in:
2020
By:
- Chen, Jing;
- Bacelis, Jonas;
- Sole-Navais, Pol;
- Srivastava, Amit;
- Juodakis, Julius;
- Rouse, Amy;
- Hallman, Mikko;
- Teramo, Kari;
- Melbye, Mads;
- Feenstra, Bjarke;
- Freathy, Rachel M.;
- Smith, George Davey;
- Lawlor, Deborah A.;
- Murray, Jeffrey C.;
- Williams, Scott M.;
- Jacobsson, Bo;
- Muglia, Louis J.;
- Zhang, Ge
Publication type:
journal article
Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease.
Published in:
PLoS Genetics, 2014, v. 10, n. 2, p. 1, doi. 10.1371/journal.pgen.1004123
By:
- Medici, Marco;
- Porcu, Eleonora;
- Pistis, Giorgio;
- Teumer, Alexander;
- Brown, Suzanne J.;
- Jensen, Richard A.;
- Rawal, Rajesh;
- Roef, Greet L.;
- Plantinga, Theo S.;
- Vermeulen, Sita H.;
- Lahti, Jari;
- Simmonds, Matthew J.;
- Husemoen, Lise Lotte N.;
- Freathy, Rachel M.;
- Shields, Beverley M.;
- Pietzner, Diana;
- Nagy, Rebecca;
- Broer, Linda;
- Chaker, Layal;
- Korevaar, Tim I. M.
Publication type:
Article
A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function.
Published in:
PLoS Genetics, 2013, v. 9, n. 2, p. 1, doi. 10.1371/journal.pgen.1003266
By:
- Porcu, Eleonora;
- Medici, Marco;
- Pistis, Giorgio;
- Volpato, Claudia B.;
- Wilson, Scott G.;
- Cappola, Anne R.;
- Bos, Steffan D.;
- Deelen, Joris;
- den Heijer, Martin;
- Freathy, Rachel M.;
- Lahti, Jari;
- Chunyu Liu;
- Lopez, Lorna M.;
- Nolte, Ilja M.;
- O'Connell, Jeffrey R.;
- Tanaka, Toshiko;
- Trompet, Stella;
- Arnold, Alice;
- Bandinelli, Stefania;
- Beekman, Marian
Publication type:
Article
Investigating a possible causal relationship between maternal serum urate concentrations and offspring birthweight: a Mendelian randomization study.
Published in:
International Journal of Epidemiology, 2023, v. 52, n. 1, p. 178, doi. 10.1093/ije/dyac186
By:
- Decina, Caitlin S;
- Hopkins, Rhian;
- Bowden, Jack;
- Shields, Beverly M;
- Lawlor, Deborah A;
- Warrington, Nicole M;
- Evans, David M;
- Freathy, Rachel M;
- Beaumont, Robin N
Publication type:
Article
Investigating the causal effect of maternal vitamin B12 and folate levels on offspring birthweight.
Published in:
2021
By:
- Moen, Gunn-Helen;
- Beaumont, Robin N;
- Grarup, Niels;
- Sommer, Christine;
- Shields, Beverley M;
- Lawlor, Deborah A;
- Freathy, Rachel M;
- Evans, David M;
- Warrington, Nicole M
Publication type:
journal article
Using a two-sample Mendelian randomization design to investigate a possible causal effect of maternal lipid concentrations on offspring birth weight.
Published in:
2019
By:
- Hwang, Liang-Dar;
- Lawlor, Deborah A;
- Freathy, Rachel M;
- Evans, David M;
- Warrington, Nicole M
Publication type:
journal article
Using genetics to understand the causal influence of higher BMI on depression.
Published in:
2019
By:
- Tyrrell, Jessica;
- Mulugeta, Anwar;
- Wood, Andrew R;
- Zhou, Ang;
- Beaumont, Robin N;
- Tuke, Marcus A;
- Jones, Samuel E;
- Ruth, Katherine S;
- Yaghootkar, Hanieh;
- Sharp, Seth;
- Thompson, William D;
- Ji, Yingjie;
- Harrison, Jamie;
- Freathy, Rachel M;
- Murray, Anna;
- Weedon, Michael N;
- Lewis, Cathryn;
- Frayling, Timothy M;
- Hyppönen, Elina
Publication type:
journal article
Using structural equation modelling to jointly estimate maternal and fetal effects on birthweight in the UK Biobank.
Published in:
2018
By:
- Warrington, Nicole M;
- Freathy, Rachel M;
- Neale, Michael C;
- Evans, David M
Publication type:
journal article
Gene-obesogenic environment interactions in the UK Biobank study.
Published in:
2017
By:
- Tyrrell, Jessica;
- Wood, Andrew R.;
- Ames, Ryan M.;
- Yaghootkar, Hanieh;
- Beaumont, Robin N.;
- Jones, Samuel E.;
- Tuke, Marcus A.;
- Ruth, Katherine S.;
- Freathy, Rachel M.;
- Smith, George Davey;
- Joost, Stéphane;
- Guessous, Idris;
- Murray, Anna;
- Strachan, David P.;
- Kutalik, Zolt_n;
- Weedon, Michael N.;
- Frayling, Timothy M.;
- Davey Smith, George;
- Kutalik, Zoltán
Publication type:
journal article
Parental diabetes and birthweight in 236 030 individuals in the UK Biobank Study.
Published in:
International Journal of Epidemiology, 2013, v. 42, n. 6, p. 1714, doi. 10.1093/ije/dyt220
By:
- Tyrrell, Jessica S;
- Yaghootkar, Hanieh;
- Freathy, Rachel M;
- Hattersley, Andrew T;
- Frayling, Timothy M
Publication type:
Article
Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index.
Published in:
2011
By:
- Freathy, Rachel M;
- Kazeem, Gbenga R;
- Morris, Richard W;
- Johnson, Paul C D;
- Paternoster, Lavinia;
- Ebrahim, Shah;
- Hattersley, Andrew T;
- Hill, Anita;
- Hingorani, Aroon D;
- Holst, Claus;
- Jefferis, Barbara J;
- Kring, Sofia I I;
- Mooser, Vincent;
- Padmanabhan, Sandosh;
- Preisig, Martin;
- Ring, Susan M;
- Sattar, Naveed;
- Upton, Mark N;
- Vollenweider, Peter;
- Waeber, Gerard
Publication type:
journal article
Common variants at 12q15 and 12q24 are associated with infant head circumference.
Published in:
Nature Genetics, 2013, v. 45, n. 6, p. 713, doi. 10.1038/ng0613-713a
By:
- Taal, H Rob;
- St Pourcain, Beate;
- Thiering, Elisabeth;
- Das, Shikta;
- Mook-Kanamori, Dennis O;
- Warrington, Nicole M;
- Kaakinen, Marika;
- Kreiner-Møller, Eskil;
- Bradfield, Jonathan P;
- Freathy, Rachel M;
- Geller, Frank;
- Guxens, Mònica;
- Cousminer, Diana L;
- Kerkhof, Marjan;
- Timpson, Nicholas J;
- Ikram, M Arfan;
- Beilin, Lawrence J;
- Bønnelykke, Klaus;
- Buxton, Jessica L;
- Charoen, Pimphen
Publication type:
Article
Common variants at 12q15 and 12q24 are associated with infant head circumference.
Published in:
Nature Genetics, 2012, v. 44, n. 5, p. 532, doi. 10.1038/ng.2238
By:
- Taal, H Rob;
- St Pourcain, Beate;
- Thiering, Elisabeth;
- Das, Shikta;
- Mook-Kanamori, Dennis O;
- Warrington, Nicole M;
- Kaakinen, Marika;
- Kreiner-Møller, Eskil;
- Bradfield, Jonathan P;
- Freathy, Rachel M;
- Geller, Frank;
- Guxens, Mònica;
- Cousminer, Diana L;
- Kerkhof, Marjan;
- Timpson, Nicholas J;
- Ikram, M Arfan;
- Beilin, Lawrence J;
- Bønnelykke, Klaus;
- Buxton, Jessica L;
- Charoen, Pimphen
Publication type:
Article
Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight.
Published in:
Nature Genetics, 2010, v. 42, n. 5, p. 430, doi. 10.1038/ng.567
By:
- Freathy, Rachel M.;
- Mook-Kanamori, Dennis O.;
- Sovio, Ulla;
- Prokopenko, Inga;
- Timpson, Nicholas J.;
- Berry, Diane J.;
- Warrington, Nicole M.;
- Widen, Elisabeth;
- Hottenga, Jouke Jan;
- Kaakinen, Marika;
- Lange, Leslie A.;
- Bradfield, Jonathan P.;
- Kerkhof, Marjan;
- Marsh, Julie A.;
- Mägi, Reedik;
- Chih-Mei Chen;
- Lyon, Helen N.;
- Kirin, Mirna;
- Adair, Linda S.;
- Aulchenko, Yurii S.
Publication type:
Article
Common variants near MC4R are associated with fat mass, weight and risk of obesity.
Published in:
Nature Genetics, 2008, v. 40, n. 6, p. 768, doi. 10.1038/ng.140
By:
- Loos, Ruth J. F.;
- Lindgren, Cecilia M.;
- Li, Shengxu;
- Wheeler, Eleanor;
- Zhao, Jing Hua;
- Prokopenko, Inga;
- Inouye, Michael;
- Freathy, Rachel M.;
- Attwood, Antony P.;
- Beckmann, Jacques S.;
- Berndt, Sonja I.;
- Jacobs, Kevin B.;
- Chanock, Stephen J.;
- Hayes, Richard B.;
- Bergmann, Sven;
- Bennett, Amanda J.;
- Bingham, Sheila A.;
- Bochud, Murielle;
- Brown, Morris;
- Cauchi, Stéphane
Publication type:
Article
Genome-wide association analysis identifies 20 loci that influence adult height.
Published in:
Nature Genetics, 2008, v. 40, n. 5, p. 575, doi. 10.1038/ng.121
By:
- Weedon, Michael N.;
- Lango, Hana;
- Lindgren, Cecilia M.;
- Wallace, Chris;
- Evans, David M.;
- Mangino, Massimo;
- Freathy, Rachel M.;
- Perry, John R. B.;
- Stevens, Suzanne;
- Hall, Alistair S.;
- Samani, Nilesh J.;
- Shields, Beverly;
- Prokopenko, Inga;
- Farrall, Martin;
- Dominiczak, Anna;
- Johnson, Toby;
- Bergmann, Sven;
- Beckmann, Jacques S.;
- Vollenweider, Peter;
- Waterworth, Dawn M.
Publication type:
Article
A common variant of HMGA2 is associated with adult and childhood height in the general population.
Published in:
Nature Genetics, 2007, v. 39, n. 10, p. 1245, doi. 10.1038/ng2121
By:
- Weedon, Michael N.;
- Lettre, Guillaume;
- Freathy, Rachel M.;
- Lindgren, Cecilia M.;
- Voight, Benjamin F.;
- Perry, John R. B.;
- Elliott, Katherine S.;
- Hackett, Rachel;
- Guiducci, Candace;
- Shields, Beverley;
- Zeggini, Eleftheria;
- Lango, Hana;
- Lyssenko, Valeriya;
- Timpson, Nicholas J.;
- Burtt, Noel P.;
- Rayner, Nigel W.;
- Saxena, Richa;
- Ardlie, Kristin;
- Tobias, Jonathan H.;
- Ness, Andrew R.
Publication type:
Article
Common maternal and fetal genetic variants show expected polygenic effects on risk of small- or large-for-gestational-age (SGA or LGA), except in the smallest 3% of babies.
Published in:
PLoS Genetics, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pgen.1009191
By:
- Beaumont, Robin N.;
- Kotecha, Sarah J.;
- Wood, Andrew R.;
- Knight, Bridget A.;
- Sebert, Sylvain;
- McCarthy, Mark I.;
- Hattersley, Andrew T.;
- Järvelin, Marjo-Riitta;
- Timpson, Nicholas J.;
- Freathy, Rachel M.;
- Kotecha, Sailesh
Publication type:
Article
Fetal alleles predisposing to metabolically favorable adiposity are associated with higher birth weight.
Published in:
Human Molecular Genetics, 2022, v. 31, n. 11, p. 1762, doi. 10.1093/hmg/ddab356
By:
- Thompson, William D;
- Beaumont, Robin N;
- Kuang, Alan;
- Warrington, Nicole M;
- Ji, Yingjie;
- Tyrrell, Jessica;
- Wood, Andrew R;
- Scholtens, Denise M;
- Knight, Bridget A;
- Evans, David M;
- Jr, William L Lowe;
- Santorelli, Gillian;
- Azad, Raq;
- Mason, Dan;
- Hattersley, Andrew T;
- Frayling, Timothy M;
- Yaghootkar, Hanieh;
- Borges, Maria Carolina;
- Lawlor, Deborah A;
- Freathy, Rachel M
Publication type:
Article
Higher adiposity and mental health: causal inference using Mendelian randomization.
Published in:
Human Molecular Genetics, 2021, v. 30, n. 24, p. 2371, doi. 10.1093/hmg/ddab204
By:
- Casanova, Francesco;
- O’Loughlin, Jessica;
- Martin, Susan;
- Beaumont, Robin N.;
- Wood, Andrew R.;
- Watkins, Edward R.;
- Freathy, Rachel M.;
- Hagenaars, Saskia P.;
- Frayling, Timothy M.;
- Yaghootkar, Hanieh;
- Tyrrell, Jess
Publication type:
Article
Common genetic variants with fetal effects on birth weight are enriched for proximity to genes implicated in rare developmental disorders.
Published in:
Human Molecular Genetics, 2021, v. 30, n. 11, p. 1057, doi. 10.1093/hmg/ddab060
By:
- Beaumont, Robin N;
- Mayne, Isabelle K;
- Freathy, Rachel M;
- Wright, Caroline F
Publication type:
Article
Genetics of early growth traits.
Published in:
Human Molecular Genetics, 2020, v. 29, n. R1, p. R66, doi. 10.1093/hmg/ddaa149
By:
- Cousminer, Diana L;
- Freathy, Rachel M
Publication type:
Article
Genetics of early growth traits.
Published in:
Human Molecular Genetics, 2020, v. 29, n. 16, p. R66, doi. 10.1093/hmg/ddaa149
By:
- Cousminer, Diana L;
- Freathy, Rachel M
Publication type:
Article
Quantifying the extent to which index event biases influence large genetic association studies.
Published in:
Human Molecular Genetics, 2017, v. 26, n. 5, p. 1018, doi. 10.1093/hmg/ddw433
By:
- Yaghootkar, Hanieh;
- Bancks, Michael P.;
- Jones, Sam E.;
- McDaid, Aaron;
- Beaumont, Robin;
- Donnelly, Louise;
- Wood, Andrew R.;
- Campbell, Archie;
- Tyrrell, Jessica;
- Hocking, Lynne J.;
- Tuke, Marcus A.;
- Ruth, Katherine S.;
- Pearson, Ewan R.;
- Murray, Anna;
- Freathy, Rachel M.;
- Munroe, Patricia B.;
- Hayward, Caroline;
- Palmer, Colin;
- Weedon, Michael N.;
- Pankow, James S.
Publication type:
Article
Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09576-1
By:
- Jones, Samuel E.;
- van Hees, Vincent T.;
- Mazzotti, Diego R.;
- Marques-Vidal, Pedro;
- Sabia, Séverine;
- van der Spek, Ashley;
- Dashti, Hassan S.;
- Engmann, Jorgen;
- Kocevska, Desana;
- Tyrrell, Jessica;
- Beaumont, Robin N.;
- Hillsdon, Melvyn;
- Ruth, Katherine S.;
- Tuke, Marcus A.;
- Yaghootkar, Hanieh;
- Sharp, Seth A.;
- Ji, Yingjie;
- Harrison, Jamie W.;
- Freathy, Rachel M.;
- Murray, Anna
Publication type:
Article
Smoking during pregnancy and its effect on placental weight: a Mendelian randomization study.
Published in:
BMC Pregnancy & Childbirth, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12884-024-06431-0
By:
- Jaitner, Annika;
- Vaudel, Marc;
- Tsaneva-Atanasova, Krasimira;
- Njølstad, Pål R.;
- Jacobsson, Bo;
- Bowden, Jack;
- Johansson, Stefan;
- Freathy, Rachel M.
Publication type:
Article
Assessing whether genetic scores explain extra variation in birthweight, when added to clinical and anthropometric measures.
Published in:
2022
By:
- Haulder, Maneka;
- Hughes, Alice E.;
- Beaumont, Robin N.;
- Knight, Bridget A.;
- Hattersley, Andrew T.;
- Shields, Beverley M.;
- Freathy, Rachel M.
Publication type:
journal article
Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile.
Published in:
Diabetologia, 2021, v. 64, n. 12, p. 2790, doi. 10.1007/s00125-021-05570-9
By:
- Thompson, William D.;
- Beaumont, Robin N.;
- Kuang, Alan;
- Warrington, Nicole M.;
- Ji, Yingjie;
- Tyrrell, Jessica;
- Wood, Andrew R.;
- Scholtens, Denise M.;
- Knight, Bridget A.;
- Evans, David M.;
- Lowe Jr, William L.;
- Santorelli, Gillian;
- Azad, Rafaq;
- Mason, Dan;
- Hattersley, Andrew T.;
- Frayling, Timothy M.;
- Yaghootkar, Hanieh;
- Borges, Maria Carolina;
- Lawlor, Deborah A.;
- Freathy, Rachel M.
Publication type:
Article
Two decades since the fetal insulin hypothesis: what have we learned from genetics?
Published in:
Diabetologia, 2021, v. 64, n. 4, p. 717, doi. 10.1007/s00125-021-05386-7
By:
- Hughes, Alice E.;
- Hattersley, Andrew T.;
- Flanagan, Sarah E.;
- Freathy, Rachel M.
Publication type:
Article
Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause and impact female reproductive health.
Published in:
2016
By:
- Ruth, KatherineS.;
- Beaumont, Robin N.;
- Tyrrell, Jessica;
- Jones, Samuel E.;
- Tuke, Marcus A.;
- Yaghootkar, Hanieh;
- Wood, Andrew R.;
- Freathy, Rachel M.;
- Weedon, Michael N.;
- Frayling, Timothy M.;
- Murray, Anna;
- Ruth, Katherine S
Publication type:
journal article
Understanding the Genetic Landscape of Gestational Diabetes: Insights into the Causes and Consequences of Elevated Glucose Levels in Pregnancy.
Published in:
Metabolites (2218-1989), 2024, v. 14, n. 9, p. 508, doi. 10.3390/metabo14090508
By:
- Brito Nunes, Caroline;
- Borges, Maria Carolina;
- Freathy, Rachel M.;
- Lawlor, Deborah A.;
- Qvigstad, Elisabeth;
- Evans, David M.;
- Moen, Gunn-Helen
Publication type:
Article
Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19257-z
By:
- Moen, Gunn-Helen;
- Brumpton, Ben;
- Willer, Cristen;
- Åsvold, Bjørn Olav;
- Birkeland, Kåre I.;
- Wang, Geng;
- Neale, Michael C.;
- Freathy, Rachel M.;
- Smith, George Davey;
- Lawlor, Deborah A.;
- Kirkpatrick, Robert M.;
- Warrington, Nicole M.;
- Evans, David M.
Publication type:
Article
The Role of Inflammatory Pathway Genetic Variation on Maternal Metabolic Phenotypes during Pregnancy.
Published in:
PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032958
By:
- Urbanek, Margrit;
- Geoffrey Hayes, M.;
- Lee, Hoon;
- Freathy, Rachel M.;
- Lowe, Lynn P.;
- Ackerman, Christine;
- Jafari, Nadereh;
- Dyer, Alan R.;
- Cox, Nancy J.;
- Dunger, David B.;
- Hattersley, Andrew T.;
- Metzger, Boyd E.;
- Lowe, William L.
Publication type:
Article
Genome-Wide and Abdominal MRI Data Provide Evidence That a Genetically Determined Favorable Adiposity Phenotype Is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease, and Hypertension.
Published in:
2019
By:
- Yingjie Ji;
- Yiorkas, Andrianos M.;
- Frau, Francesca;
- Mook-Kanamori, Dennis;
- Staiger, Harald;
- Thomas, E.Louise;
- Atabaki-Pasdar, Naeimeh;
- Campbell, Archie;
- Tyrrell, Jessica;
- Jones, Samuel E.;
- Beaumont, Robin N.;
- Wood, Andrew R.;
- Tuke, Marcus A.;
- Ruth, Katherine S.;
- Mahajan, Anubha;
- Murray, Anna;
- Freathy, Rachel M.;
- Weedon, Michael N.;
- Hattersley, Andrew T.;
- Hayward, Caroline
Publication type:
journal article
Fetal Genotype and Maternal Glucose Have Independent and Additive Effects on Birth Weight.
Published in:
2018
By:
- Hughes, Alice E.;
- Nodzenski, Michael;
- Beaumont, Robin N.;
- Talbot, Octavious;
- Shields, Beverley M.;
- Scholtens, Denise M.;
- Knight, Bridget A.;
- Lowe Jr., William L.;
- Hattersley, Andrew T.;
- Freathy, Rachel M.;
- Lowe, William L Jr
Publication type:
journal article
Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease.
Published in:
2016
By:
- Yaghootkar, Hanieh;
- Lotta, Luca A.;
- Tyrrell, Jessica;
- Smit, Roelof A. J.;
- Jones, Sam E.;
- Donnelly, Louise;
- Beaumont, Robin;
- Campbell, Archie;
- Tuke, Marcus A.;
- Hayward, Caroline;
- Ruth, Katherine S.;
- Padmanabhan, Sandosh;
- Wouter Jukema, J.;
- Palmer, Colin C.;
- Hattersley, Andrew;
- Freathy, Rachel M.;
- Langenberg, Claudia;
- Wareham, Nicholas J.;
- Wood, Andrew R.;
- Murray, Anna
Publication type:
journal article
Association Analysis of 29,956 Individuals Confirms That a Low-Frequency Variant at CCND2 Halves the Risk of Type 2 Diabetes by Enhancing Insulin Secretion.
Published in:
Diabetes, 2015, v. 64, n. 6, p. 2279, doi. 10.2337/db14-1456
By:
- Yaghootkar, Hanieh;
- Stancáková, Alena;
- Freathy, Rachel M.;
- Vangipurapu, Jagadish;
- Weedon, Michael N.;
- Weijia Xie;
- Wood, Andrew R.;
- Ferrannini, Ele;
- Mari, Andrea;
- Ring, Susan M.;
- Lawlor, Debbie A.;
- Smith, George Davey;
- Jørgensen, Torben;
- Hansen, Torben;
- Pedersen, Oluf;
- Steinthorsdottir, Valgerdur;
- Guðbjartsson, Daniel F.;
- Thorleifsson, Gudmar;
- Thorsteinsdottir, Unnur;
- Stefansson, Kari
Publication type:
Article