Works by Frayn, Keith

Results: 48

Adipose dipeptidyl peptidase-4 and obesity: correlation with insulin resistance and depot-specific release from adipose tissue in vivo and in vitro.
Published in:
2013
By:
- Sell, Henrike;
- Blüher, Matthias;
- Klöting, Nora;
- Schlich, Raphaela;
- Willems, Miriam;
- Ruppe, Florian;
- Knoefel, Wolfram Trudo;
- Dietrich, Arne;
- Fielding, Barbara A;
- Arner, Peter;
- Frayn, Keith N;
- Eckel, Jürgen
Publication type:
journal article
Adipose Dipeptidyl Peptidase-4 and Obesity.
Published in:
Diabetes Care, 2013, v. 36, n. 12, p. 4083, doi. 10.2337/dc13-0496
By:
- SELL, HENRIKE;
- BLUHER, MATTHIAS;
- KLÖTING, NORA;
- SCHLICH, RAPHAELA;
- WILLEMS, MIRIAM;
- RUPPE, FLORIAN;
- KNOEFEL, WOLFRAM TRUDO;
- DIETRICH, ARNE;
- FIELDING, BARBARA A.;
- ARNER, PETER;
- FRAYN, KEITH N.;
- ECKEL, JURGEN
Publication type:
Article
Mapping of the Fibroblast Growth Factors in Human White Adipose Tissue.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2010, v. 95, n. 5, p. 2451, doi. 10.1210/jc.2009-2049
By:
- Mejhert, Niklas;
- Galitzky, Jean;
- Pettersson, Amanda T.;
- Bambace, Clara;
- Blomqvist, Lennart;
- Bouloumié, Anne;
- Frayn, Keith N.;
- Dahlman, Ingrid;
- Arner, Peter;
- Rydén, Mikael
Publication type:
Article
Fasted to Fed Trafficking of Fatty Acids in Human Adipose Tissue Reveals a Novel Regulatory Step for Enhanced Fat Storage.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2009, v. 94, n. 5, p. 1781, doi. 10.1210/jc.2008-2090
By:
- Ruge, Toralph;
- Hodson, Leanne;
- Cheeseman, Jane;
- Dennis, A. Louise;
- Fielding, Barbara A.;
- Humphreys, Sandy M.;
- Frayn, Keith N.;
- Karpe, Fredrik
Publication type:
Article
Fatty acid metabolism in patients with PPARgamma mutations.
Published in:
2008
By:
- Tan, Garry D;
- Savage, David B;
- Fielding, Barbara A;
- Collins, Jenny;
- Hodson, Leanne;
- Humphreys, Sandy M;
- O'Rahilly, Stephen;
- Chatterjee, Krishna;
- Frayn, Keith N;
- Karpe, Fredrik
Publication type:
journal article
Effects of physiological hypercortisolemia on the regulation of lipolysis in subcutaneous adipose tissue.
Published in:
1998
By:
- SAMRA, JASWINDER S.;
- CLARK, MO L.;
- HUMPHREYS, SANDY M.;
- MACDONALD, IAN A.;
- BANNISTER, PETER A.;
- FRAYN, KEITH N.
Publication type:
journal article
Insulin Resistance, Impaired Postprandial Lipid Metabolism and Abdominal Obesity.
Published in:
Medical Principles & Practice, 2002, v. 11, p. 31, doi. 10.1159/000066414
By:
- Frayn, Keith N.
Publication type:
Article
Insulin resistance, impaired postprandial lipid metabolism and abdominal obesity. A deadly triad.
Published in:
2002
By:
- Frayn, Keith N
Publication type:
journal article
Dynamics of human adipose lipid turnover in health and metabolic disease.
Published in:
Nature, 2011, v. 478, n. 7367, p. 110, doi. 10.1038/nature10426
By:
- Arner, Peter;
- Bernard, Samuel;
- Salehpour, Mehran;
- Possnert, Göran;
- Liebl, Jakob;
- Steier, Peter;
- Buchholz, Bruce A.;
- Eriksson, Mats;
- Arner, Erik;
- Hauner, Hans;
- Skurk, Thomas;
- Rydén, Mikael;
- Frayn, Keith N.;
- Spalding, Kirsty L.
Publication type:
Article
Effects of ageing on the initial metabolic response to accidential injury.
Published in:
Age & Ageing, 1998, v. 27, n. 3, p. 321, doi. 10.1093/ageing/27.3.321
By:
- Barton, Roger N.;
- Frayn, Keith N.;
- Berrington Stoner, H.;
- Little, Roderick A.
Publication type:
Article
Downregulation of Adipose Tissue Fatty Acid Trafficking in Obesity.
Published in:
Diabetes, 2011, v. 60, n. 1, p. 47, doi. 10.2337/db10-0867
By:
- McQuaid, Siobhán E.;
- Hodson, Leanne;
- Neville, Matthew J.;
- Dennis, A. Louise;
- Cheeseman, Jane;
- Humphreys, Sandy M.;
- Ruge, Toralph;
- Gilbert, Marjorie;
- Fielding, Barbara A.;
- Frayn, Keith N.;
- Karpe, Fredrik
Publication type:
Article
Femoral Adipose Tissue May Accumulate the Fat That Has Been Recycled as VLDL and Nonesterified Fatty Acids.
Published in:
Diabetes, 2010, v. 59, n. 10, p. 2465, doi. 10.2337/db10-0678
By:
- McQuaid, Siobhán E.;
- Humphreys, Sandy M.;
- Hodson, Leanne;
- Fielding, Barbara A.;
- Karpe, Fredrik;
- Frayn, Keith N.
Publication type:
Article
Elevated Expression of Osteopontin May Be Related to Adipose Tissue Macrophage Accumulation and Liver Steatosis in Morbid Obesity.
Published in:
Diabetes, 2009, v. 58, n. 1, p. 125, doi. 10.2337/db08-0400
By:
- Bertola, Adeline;
- Deveaux, Vanessa;
- Bonnafous, Stéphanie;
- Rousseau, Déborah;
- Anty, Rodolphe;
- Wakkach, Abdelilah;
- Dahman, Moncef;
- Tordjman, Joan;
- Clément, Karine;
- McQuaid, Siobhán E.;
- Frayn, Keith N.;
- Huet, Pierre-Michel;
- Gugenheim, Jean;
- Lotersztajn, Sophie;
- Le Marchand-Brustel, Yannick;
- Tran, Albert;
- Gual, Philippe
Publication type:
Article
Vascular Peptide Endothelin-1 Links Fat Accumulation With Alterations of Visceral Adipocyte Lipolysis.
Published in:
Diabetes, 2008, v. 57, n. 2, p. 378, doi. 10.2337/db07-0893
By:
- van Harmelen, Vanessa;
- Eriksson, Anna;
- Åström, Gaby;
- Wåhlén, Kerstin;
- Näslund, Erik;
- Karpe, Fredrik;
- Frayn, Keith;
- Olsson, Tommy;
- Andersson, Jonas;
- Rydén, Mikel;
- Arner, Peter
Publication type:
Article
The Contribution of Splanchnic Fat to VLDL Triglyceride Is Greater in Insulin-Resistant Than Insulin-Sensitive Men and Women.
Published in:
Diabetes, 2007, v. 56, n. 10, p. 2433, doi. 10.2337/db07-0654
By:
- Hodson, Leanne;
- Bickerton, Alex S. T.;
- McQuaid, Siobhán E.;
- Roberts, Rachel;
- Karpe, Fredrik;
- Frayn, Keith N.;
- Fielding, Barbara A.
Publication type:
Article
Preferential Uptake of Dietary Fatty Acids in Adipose Tissue and Muscle in the Postprandial Period.
Published in:
Diabetes, 2007, v. 56, n. 1, p. 168, doi. 10.2337/db06-0822
By:
- Bickerton, Alex S. T.;
- Roberts, Rachel;
- Fielding, Barbara A.;
- Hodson, Leanne;
- Blaack, Ellen E.;
- Wagenmakers, Anton J. M.;
- Gilbert, Marjorie;
- Karpe, Fredrik;
- Frayn, Keith N.
Publication type:
Article
Rosiglitazone increases indexes of stearoyl-CoA desaturase activity in humans: link to insulin sensitization and the role of dominant-negative mutation in peroxisome proliferator-activated receptor-gamma.
Published in:
2005
By:
- Risérus, Ulf;
- Tan, Garry D.;
- Fielding, Barbara A.;
- Neville, Matt J.;
- Currie, Jenny;
- Savage, David B.;
- Chatterjee, V. Krishna;
- Frayn, Keith N.;
- O'Rahilly, Stephen;
- Karpe, Fredrik;
- Risérus, Ulf
Publication type:
journal article
Oscillations of fatty acid and glycerol release from human subcutaneous adipose tissue in vivo.
Published in:
2005
By:
- Karpe, Fredrik;
- Fielding, Barbara A.;
- Coppack, Simon W.;
- Lawrence, Victor J.;
- Macdonald, Ian A.;
- Frayn, Keith N.
Publication type:
journal article
Regulation of dietary fatty acid entrapment in subcutaneous adipose tissue and skeletal muscle.
Published in:
2002
By:
- Evans, Kevin;
- Burdge, Graham C.;
- Wootton, Stephen A.;
- Clark, Mo L.;
- Frayn, Keith N.
Publication type:
journal article
Impaired postprandial adipose tissue blood flow response is related to aspects of insulin sensitivity.
Published in:
2002
By:
- Karpe, Fredrik;
- Fielding, Barbara A.;
- Ilic, Vera;
- Macdonald, Ian A.;
- Summers, Lucinda K.M.;
- Frayn, Keith N.
Publication type:
journal article
Metabolic interaction of dietary sugars and plasma lipids with a focus on mechanisms and de novo lipogenesis.
Published in:
Proceedings of the Nutrition Society, 2007, v. 66, n. 1, p. 52, doi. 10.1017/S0029665107005290
By:
- Chong, Mary F. F.;
- Fielding, Barbara A.;
- Frayn, Keith N.
Publication type:
Article
Obesity and metabolic disease: is adipose tissue the culprit?
Published in:
2005
By:
- Frayn KN;
- Frayn, Keith N
Publication type:
journal article
Obesity and metabolic disease: is adipose tissue the culprit?
Published in:
Proceedings of the Nutrition Society, 2005, v. 64, n. 1, p. 7, doi. 10.1079/PNS2004403
By:
- Frayn, Keith N.
Publication type:
Article
Adipose tissue and the insulin resistance syndrome.
Published in:
Proceedings of the Nutrition Society, 2001, v. 60, n. 3, p. 375, doi. 10.1079/PNS200195
By:
- Frayn, Keith N.
Publication type:
Article
Macronutrient metabolism of adipose tissue at rest and during exercise: a methodological viewpoint.
Published in:
Proceedings of the Nutrition Society, 1999, v. 58, n. 4, p. 877, doi. 10.1017/S0029665199001184
By:
- Frayn, Keith N.
Publication type:
Article
Regulation of the plasma non-esterified fatty acid concentration in the postprandial state.
Published in:
Proceedings of the Nutrition Society, 1997, v. 56, n. 2, p. 713, doi. 10.1079/PNS19970071
By:
- Frayn, Keith N.;
- Summers, Lucinda K. M.;
- Fielding, Barbara A.
Publication type:
Article
The acylation-stimulating protein pathway and regulation of postprandial metabolism.
Published in:
Proceedings of the Nutrition Society, 1997, v. 56, n. 2, p. 703, doi. 10.1079/PNS19970070
By:
- Sniderman, Allan D.;
- Cianflone, Katherine;
- Summers, Lucinda;
- Fielding, Barbara;
- Frayn, Keith
Publication type:
Article
Fuel selection in white adipose tissue.
Published in:
Proceedings of the Nutrition Society, 1995, v. 54, n. 1, p. 177, doi. 10.1079/PNS19950047
By:
- Frayn, Keith N.;
- Humphreys, Sandy M.;
- Coppack, Simon W.
Publication type:
Article
Effect of diet on human adipose tissue metabolism.
Published in:
Proceedings of the Nutrition Society, 1992, v. 51, n. 3, p. 409, doi. 10.1079/PNS19920054
By:
- Frayn, Keith N.;
- Coppack, Simon W.;
- Potts, Jennifer L.
Publication type:
Article
Effects of insulin on adipose tissue blood flow in man.
Published in:
Journal of Physiology, 2002, v. 540, n. 3, p. 1087, doi. 10.1113/jphysiol.2001.013358
By:
- Karpe, Fredrik;
- Fielding, Barbara A.;
- Ardilouze, Jean-Luc;
- Ilic, Vera;
- Macdonald, Ian A.;
- Frayn, Keith N.
Publication type:
Article
PASSCLAIM<sup>1</sup>—Body weight regulation, insulin sensitivity and diabetes risk.
Published in:
European Journal of Nutrition, 2004, v. 43, p. ii7
By:
- Riccardi, Gabriele;
- Aggett, Peter;
- Brighenti, Furio;
- Delzenne, Nathalie;
- Frayn, Keith;
- Nieuwenhuizen, Arie;
- Pannemans, Daphne;
- Theis, Stephan;
- Tuijtelaars, Sandra;
- Vessby, Bengt
Publication type:
Article
Plasma non-esterified fatty acids: why are we not measuring them routinely?
Published in:
Annals of Clinical Biochemistry, 2005, v. 42, n. 6, p. 413, doi. 10.1258/000456305774538247
By:
- Frayn, Keith N
Publication type:
Article
Liver fat and lipid oxidation in humans.
Published in:
Liver International, 2009, v. 29, n. 9, p. 1439, doi. 10.1111/j.1478-3231.2009.02076.x
By:
- Kotronen, Anna;
- Seppälä-Lindroos, Anneli;
- Vehkavaara, Satu;
- Bergholm, Robert;
- Frayn, Keith N.;
- Fielding, Barbara A.;
- Yki-Järvinen, Hannele
Publication type:
Article
Development of an Arterio-venous Difference Method to Study the Metabolic Physiology of the Femoral Adipose Tissue Depot.
Published in:
Obesity (19307381), 2010, v. 18, n. 5, p. 1055, doi. 10.1038/oby.2009.486
By:
- McQuaid, Siobhán E.;
- Manolopoulos, Konstantinos N.;
- Dennis, A. Louise;
- Cheeseman, Jane;
- Karpe, Fredrik;
- Frayn, Keith N.
Publication type:
Article
Transcriptional Control of Human Adipose Tissue Blood Flow.
Published in:
Obesity (19307381), 2009, v. 17, n. 4, p. 681, doi. 10.1038/oby.2008.606
By:
- Perez-Matute, Patricia;
- Neville, Matthew J.;
- Tan, Garry D.;
- Frayn, Keith N.;
- Karpe, Fredrik
Publication type:
Article
A futile cycle" induced by thiazolidinediones in human adipose tissue?
Published in:
Nature Medicine, 2003, v. 9, n. 7, p. 811, doi. 10.1038/nm0703-811
By:
- Tan, Garry D;
- Debard, Cyrille;
- Tiraby, Claire;
- Humphreys, Sandy M;
- Frayn, Keith N;
- Langin, Dominique;
- Vidal, Hubert;
- Karpe, Fredrik
Publication type:
Article
Metabolism of individual fatty acids during infusion of a triacylglycerol emulsion.
Published in:
Lipids, 1999, v. 34, n. 6, p. 535, doi. 10.1007/s11745-999-0395-3
By:
- Fielding, Barbara;
- Samra, Jaswinder;
- Ravell, Cate;
- Frayn, Keith
Publication type:
Article
Fuel preferences in the septic patient: glucose or lipid?
Published in:
1988
By:
- Frayn, Keith N.;
- Frayn, K N
Publication type:
Letter
Hormonal and metabolic responses to glucose infusion in sepsis studied by the hyperglycemic glucose clamp technique.
Published in:
1987
By:
- White, Roger H.;
- Frayn, Keith N.;
- Little, Roderick A.;
- Threlfall, Cedric J.;
- Stoner, H.B.;
- Irving, Miles H.;
- White, R H;
- Frayn, K N;
- Little, R A;
- Threlfall, C J;
- Irving, M H
Publication type:
journal article
Turning over our fat stores: the key to metabolic health Blaxter Award Lecture 2018.
Published in:
2019
By:
- Frayn, Keith N.
Publication type:
journal article
Enhanced fatty acid uptake in visceral adipose tissue is not reversed by weight loss in obese individuals with the metabolic syndrome.
Published in:
Diabetologia, 2015, v. 58, n. 1, p. 158, doi. 10.1007/s00125-014-3402-x
By:
- Bucci, Marco;
- Karmi, Anna;
- Iozzo, Patricia;
- Fielding, Barbara;
- Viljanen, Antti;
- Badeau, Robert;
- Borra, Ronald;
- Saunavaara, Virva;
- Pham, Tam;
- Hannukainen, Jarna;
- Kalliokoski, Kari;
- Haaparanta-Solin, Merja;
- Viljanen, Tapio;
- Parkkola, Riitta;
- Frayn, Keith;
- Nuutila, Pirjo
Publication type:
Article
Suppression of the nocturnal rise in growth hormone reduces subsequent lipolysis in subcutaneous adipose tissue.
Published in:
European Journal of Clinical Investigation, 1999, v. 29, n. 12, p. 1045, doi. 10.1046/j.1365-2362.1999.00577.x
By:
- Samra;
- Clark;
- Humphreys;
- Macdonald;
- Bannister;
- Matthews;
- Frayn;
- Frayn, Keith N.
Publication type:
Article
Altered Desaturation and Elongation of Fatty Acids in Hormone-Sensitive Lipase Null Mice.
Published in:
PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0021603
By:
- Fernandez, Céline;
- Schuhmann, Kai;
- Herzog, Ronny;
- Fielding, Barbara;
- Frayn, Keith;
- Shevchenko, Andrej;
- James, Peter;
- Holm, Cecilia;
- Ström, Kristoffer
Publication type:
Article
Substrate Utilization by the Failing Human Heart by Direct Quantification Using Arterio-Venous Blood Sampling.
Published in:
PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007533
By:
- Funada, Junichi;
- Betts, Tim R.;
- Hodson, Leanne;
- Humphreys, Sandy M.;
- Timperley, Jon;
- Frayn, Keith N.;
- Karpe, Fredrik
Publication type:
Article
Distinct Developmental Profile of Lower-Body Adipose Tissue Defines Resistance Against Obesity-Associated Metabolic Complications.
Published in:
Diabetes, 2014, v. 63, n. 11, p. 3785, doi. 10.2337/db14-0385
By:
- Pinnick, Katherine E.;
- Nicholson, George;
- Manolopoulos, Konstantinos N.;
- McQuaid, Siobhán E.;
- Valet, Philippe;
- Frayn, Keith N.;
- Denton, Nathan;
- Min, Josine L.;
- Zondervan, Krina T.;
- Fleckner, Jan;
- McCarthy, Mark I.;
- Holmes, Chris C.;
- Karpe, Fredrik
Publication type:
Article
Metabolic Signatures of Human Adipose Tissue Hypoxia in Obesity.
Published in:
Diabetes, 2013, v. 62, n. 5, p. 1417, doi. 10.2337/db12-1032
By:
- Hodson, Leanne;
- Humphreys, Sandy M.;
- Karpe, Fredrik;
- Frayn, Keith N.
Publication type:
Article
Gluteofemoral Adipose Tissue Plays a Major Role in Production of the Lipokine Palmitoleate in Humans.
Published in:
Diabetes, 2012, v. 61, n. 6, p. 1399, doi. 10.2337/db11-1810
By:
- Pinnick, Katherine E.;
- Neville, Matt J.;
- Fielding, Barbara A.;
- Frayn, Keith N.;
- Karpe, Fredrik;
- Hodson, Leanne
Publication type:
Article
Fatty Acids, Obesity, and Insulin Resistance: Time for a Reevaluation.
Published in:
Diabetes, 2011, v. 60, n. 10, p. 2441, doi. 10.2337/db11-0425
By:
- Karpe, Fredrik;
- Dickmann, Julian R.;
- Frayn, Keith N.
Publication type:
Article