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Use of Copper and Insulin-Resistance to Accelerate Cognitive Deficits and Synaptic Protein Loss in a Rat Aβ-Infusion Alzheimer's Disease Model.
- Published in:
- Journal of Alzheimer's Disease, 2008, v. 15, n. 4, p. 625, doi. 10.3233/JAD-2008-15409
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- Publication type:
- Article
Editorial: Oxidative Stress in Myocardial and Neural Remodeling.
- Published in:
- 2021
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- Publication type:
- Editorial
The novel omega‐6 fatty acid docosapentaenoic acid positively modulates brain innate immune response for resolving neuroinflammation at early and late stages of humanized APOE‐based Alzheimer's disease models: Nonhuman/Target identification and validation studies: Inflammation and innate immunity
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044178
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- Publication type:
- Article
P4‐683: OMEGA‐6 FATTY ACIDS AS A NOVEL IMMUNOTHERAPEUTIC APPROACH FOR THE TREATMENT OF ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1593, doi. 10.1016/j.jalz.2019.09.048
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- Publication type:
- Article
P3‐147: APOLIPOPROTEIN E ISOTYPE AND EXERCISE INTERACT IN THE EPIGENETIC REGULATION OF MICRORNA‐146A.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P987, doi. 10.1016/j.jalz.2019.06.3175
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- Publication type:
- Article
P2‐211: PHARMACOGENOMIC IMPACT OF APOE4 ON TRANSCIPTIONAL REGULATION OF MICROGLIA IN AD MODEL MICE: IMPLICATIONS FOR PREVENTION AND TREATMENT.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P658, doi. 10.1016/j.jalz.2019.06.2618
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- Publication type:
- Article
O2‐04‐04: A NOVEL TRANSGENIC RAT MODEL FOR MIXED DEMENTIA.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P544, doi. 10.1016/j.jalz.2019.06.4472
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- Publication type:
- Article
Characterization of a Bioactive Peptide T14 in the Human and Rodent Substantia Nigra: Implications for Neurodegenerative Disease.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13119, doi. 10.3390/ijms232113119
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- Publication type:
- Article
Pituitary Portal Plasma Levels of Oxytocin during the Estrous Cycle, Lactation, and Hyperprolactinemia.
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- Annals of the New York Academy of Sciences, 1992, v. 652, n. 1, p. 397, doi. 10.1111/j.1749-6632.1992.tb34370.x
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- Publication type:
- Article
Dietary fatty acids and the aging brain.
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- Nutrition Reviews, 2010, v. 68, p. S102, doi. 10.1111/j.1753-4887.2010.00345.x
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- Publication type:
- Article
Editorial: Role of Inflammation in Neurodegenerative Diseases.
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- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.958487
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- Publication type:
- Article
DIETARY LINOLEIC ACID DIFFERENTIALLY INFLUENCES BRAIN FADS ACTIVITIES INCREASING AN N-6 METABOLITE THAT INHIBITS INFLAMMATION AND PROMOTES AMYLOID-β CLEARANCE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P982, doi. 10.1016/j.jalz.2017.06.1335
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- Publication type:
- Article
APOE4-DEPENDENT SYNAPTIC-DERIVED PLASMA BIOMARKERS IN ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P875, doi. 10.1016/j.jalz.2016.06.1807
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- Publication type:
- Article
Release of c-terminal truncated and intact tau from Alzheimer's disease cortical synapses.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P186, doi. 10.1016/j.jalz.2015.07.161
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- Publication type:
- Article
Lysine-specific molecular tweezers protect neurons against beta-amyloid-induced synaptotoxicity and lower beta-amyloid and p-tau load in a mouse model of Alzheimer's disease
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- 2012
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- Publication type:
- Abstract
Impact of diet and exercise on the development of tau pathology
- Published in:
- 2012
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- Publication type:
- Abstract
Curcumin modulation of molecular chaperones in amyloidogenic models of neurodegenerative diseases
- Published in:
- 2012
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- Publication type:
- Abstract
Late-stage intervention with curcumin reduces soluble tau oligomers and corrects cognitive and synaptic deficits
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- 2011
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- Publication type:
- Abstract
Early intervention with docosahexanoic Acid (DHA) protects APOE4 acceleration of cognitive decline and plasma biomarkers in APOE4/5xFAD mice
- Published in:
- 2011
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- Publication type:
- Abstract
Protection of excitatory synapses by DHA through preserving function of NMDA-Tiam1-PAK signal pathway in Alzheimer models
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- 2010
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- Publication type:
- Abstract
Novel, small molecule inhibitors of protein aggregation for treatment of amyloid-related diseases
- Published in:
- 2010
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- Publication type:
- Abstract
Increased expression of sodium-calcium exchanger 3 (NCX3) in amyloid-beta positive synaptosomes
- Published in:
- 2009
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- Publication type:
- Abstract
P4-344: Oral curcumin for the treatment of mild-to-moderate Alzheimer's disease: Tolerability and clinical and biomarker efficacy results of a placebo-controlled 24-week study
- Published in:
- 2008
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- Publication type:
- Abstract
P4-272: P21-activated kinase aberrant activation and translocation in Alzheimer's disease pathogenesis
- Published in:
- 2008
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- Publication type:
- Abstract
P3-064: Can SorLA/LR11, a sorting protein limiting Abeta production, serve as both therapeutic and diagnostic target in Alzheimer's disease?
- Published in:
- 2008
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- Publication type:
- Abstract
O1-02-08: DHA, amyloid, GSK3β, trophic signaling and AD prevention
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- 2007
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- Publication type:
- Abstract
Commentary on “Cytoskeletal modulators and pleiotropic strategies for Alzheimer drug discovery.” Pleiotropic approaches to Alzheimer’s and other diseases of aging
- Published in:
- 2006
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- Publication type:
- Editorial
O3-02-05: p21-activated kinase pathway defects and synaptic function in Alzheimer’s disease
- Published in:
- 2006
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- Publication type:
- Abstract
O3-02-05: p21-activated kinase pathway defects and synaptic function in Alzheimer’s disease
- Published in:
- 2006
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- Publication type:
- Abstract
What causes and how can we prevent cognitive deficits in Alzheimer’s (AD)?
- Published in:
- 2005
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- Publication type:
- Abstract
Antibodies against β‐amyloid reduce aβ oligomers, glycogen synthase kinase‐3β activation and τ phosphorylation in vivo and in vitro.
- Published in:
- Journal of Neuroscience Research, 2006, v. 83, n. 3, p. 374
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- Publication type:
- Article
Role of LRP in TGFβ2‐mediated neuronal uptake of Aβ and effects on memory.
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- Journal of Neuroscience Research, 2004, v. 77, n. 2, p. 217, doi. 10.1002/jnr.20149
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- Publication type:
- Article
Lipoprotein effects on aβ accumulation and degradation by microglia in vitro.
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- Journal of Neuroscience Research, 1999, v. 57, n. 4, p. 504, doi. 10.1002/(SICI)1097-4547(19990815)57:4<504::AID-JNR10>3.0.CO;2-H
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- Publication type:
- Article
NSAID and Antioxidant Prevention of Alzheimer's Disease: Lessons from In Vitro and Animal Models.
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- Annals of the New York Academy of Sciences, 2004, v. 1035, n. 1, p. 68, doi. 10.1196/annals.1332.005
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- Publication type:
- Article
β-Amyloid Oligomers Induce Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate via c-Jun N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and Curcumin.
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- Journal of Neuroscience, 2009, v. 29, n. 28, p. 9078, doi. 10.1523/JNEUROSCI.1071-09.2009
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- Publication type:
- Article
Omega-3 Fatty Acid Docosahexaenoic Acid Increases SorLA/LR11, a Sorting Protein with Reduced Expression in Sporadic Alzheimer's Disease (AD): Relevance to AD Prevention.
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- Journal of Neuroscience, 2007, v. 27, n. 52, p. 14299, doi. 10.1523/JNEUROSCI.3593-07.2007
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- Publication type:
- Article
A Diet Enriched with the Omega-3 Fatty Acid Docosahexaenoic Acid Reduces Amyloid Burden in an Aged Alzheimer Mouse Model.
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- Journal of Neuroscience, 2005, v. 25, n. 12, p. 3032, doi. 10.1523/JNEUROSCI.4225-04.2005
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- Publication type:
- Article
Insulin-Degrading Enzyme as a Downstream Target of Insulin Receptor Signaling Cascade: Implications for Alzheimer's Disease Intervention.
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- Journal of Neuroscience, 2004, v. 24, n. 49, p. 11120, doi. 10.1523/JNEUROSCI.2860-04.2004
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- Publication type:
- Article
Ibuprofen Suppresses lnterleukin-1β Induction of Pro-Amyloidogenic β<sub>1</sub>-Antichymotrypsin to Ameliorate β-Amyloid (Aβ) Pathology in Alzheimer's Models.
- Published in:
- Neuropsychopharmacology, 2005, v. 30, n. 6, p. 1111, doi. 10.1038/sj.npp.1300668
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- Article
Protection of primary neurons and mouse brain from Alzheimer’s pathology by molecular tweezers.
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- Brain: A Journal of Neurology, 2012, v. 135, n. 12, p. 3735, doi. 10.1093/brain/aws289
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- Publication type:
- Article
Cyclooxygenase-2 inhibition improves amyloid-{beta}-mediated suppression of memory and synaptic plasticity.
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- Brain: A Journal of Neurology, 2008, v. 131, n. 3, p. 651, doi. 10.1093/brain/awn008
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- Publication type:
- Article
Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study.
- Published in:
- Alzheimer's Research & Therapy, 2012, v. 4, n. 5, p. 43, doi. 10.1186/alzrt146
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- Publication type:
- Article
What was lost in translation in the DHA trial is whom you should intend to treat.
- Published in:
- Alzheimer's Research & Therapy, 2011, v. 3, n. 1, p. 1, doi. 10.1186/alzrt61
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- Publication type:
- Article
Effects of Transforming Growth Factor β<sub>1</sub>, on Scar Production in the Injured Central Nervous System of the Rat.
- Published in:
- European Journal of Neuroscience, 1994, v. 6, n. 3, p. 355, doi. 10.1111/j.1460-9568.1994.tb00278.x
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- Publication type:
- Article
A novel process driving Alzheimer's disease validated in a mousemodel: Therapeutic potential.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2022, v. 8, n. 1, p. 1, doi. 10.1002/trc2.12274
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- Publication type:
- Article
Retinal Venular Tortuosity Jointly with Retinal Amyloid Burden Correlates with Verbal Memory Loss: A Pilot Study.
- Published in:
- Cells (2073-4409), 2021, v. 10, n. 11, p. 2926, doi. 10.3390/cells10112926
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- Publication type:
- Article
Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease.
- Published in:
- Nature Neuroscience, 2006, v. 9, n. 2, p. 234, doi. 10.1038/nn1630
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- Publication type:
- Article
Expression of Basic Fibroblast Growth Factor and Its Receptor in the Rat Subfornical Organ.
- Published in:
- Neuroendocrinology, 1991, v. 54, n. 1, p. 62, doi. 10.1159/000125852
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- Publication type:
- Article
Facilitatory Role of Neuropeptide Y on the Onset of Puberty: Effect of Immunoneutralization of Neuropeptide Yon the Release of Luteinizing Hormone and Luteinizing-Hormone-Releasing Hormone.
- Published in:
- Neuroendocrinology, 1990, v. 52, n. 1, p. 112, doi. 10.1159/000125548
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- Publication type:
- Article
Chronic Inhibition of Hypothalamic-Pituitary-Ovarian Axis and Body Weight Gain by Brain-Directed Delivery of Estradiol-17β in Female Rats.
- Published in:
- Neuroendocrinology, 1989, v. 50, n. 2, p. 204, doi. 10.1159/000125223
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- Publication type:
- Article