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Priorities in Parkinson's disease research.
Published in:
2011
By:
- Meissner, Wassilios G.;
- Frasier, Mark;
- Gasser, Thomas;
- Goetz, Christopher G.;
- Lozano, Andres;
- Piccini, Paola;
- Obeso, José A.;
- Rascol, Olivier;
- Schapira, Anthony;
- Voon, Valerie;
- Weiner, David M.;
- Tison, François;
- Bezard, Erwan;
- Obeso, José A;
- Tison, François
Publication type:
journal article
Evaluation of the PREDIGT score's performance in identifying newly diagnosed Parkinson's patients without motor examination.
Published in:
NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00360-5
By:
- Li, Juan;
- Mestre, Tiago A.;
- Mollenhauer, Brit;
- Frasier, Mark;
- Tomlinson, Julianna J.;
- Trenkwalder, Claudia;
- Ramsay, Tim;
- Manuel, Douglas;
- Schlossmacher, Michael G.
Publication type:
Article
Diurnal and intersubject variability of cerebrospinal fluid biomarkers, Aβ-40/42, alpha-synuclein and DJ-1 in healthy volunteers
Published in:
2012
By:
- Ereshefsky, Larry;
- Frasier, Mark;
- Yen, Mark;
- Jhee, Stanford;
- Marek, Kenneth;
- Taylor, Peggy;
- Sherman, Molly;
- Caspell, Chelsea;
- Coffey, Chris;
- Schlossmacher, Michael;
- Sherer, Todd
Publication type:
Abstract
P3-444: Proteasomal inhibition increases alpha-synuclein levels in an amyloid-beta-dependent manner
Published in:
2006
By:
- Frasier, Mark;
- DeLong, Cynthia;
- Bales, Kelly;
- Merchant, Kalpana M.
Publication type:
Abstract
P3-231: Biochemical and histological studies of leucine rich repeat kinase 2 (LRRK2)
Published in:
2006
By:
- Merchant, Kalpana M.;
- Frasier, Mark;
- Tzaferis, John;
- Li, Linglin;
- Ryder, John;
- DeLong, Cynthia;
- Bales, Kelly;
- Kingston, Ann E.
Publication type:
Abstract
P3-444: Proteasomal inhibition increases alpha-synuclein levels in an amyloid-beta-dependent manner
Published in:
2006
By:
- Frasier, Mark;
- DeLong, Cynthia;
- Bales, Kelly;
- Merchant, Kalpana M.
Publication type:
Abstract
P3-231: Biochemical and histological studies of leucine rich repeat kinase 2 (LRRK2)
Published in:
2006
By:
- Merchant, Kalpana M.;
- Frasier, Mark;
- Tzaferis, John;
- Li, Linglin;
- Ryder, John;
- DeLong, Cynthia;
- Bales, Kelly;
- Kingston, Ann E.
Publication type:
Abstract
Loss of Leucine-Rich Repeat Kinase 2 (LRRK2) in Rats Leads to Progressive Abnormal Phenotypes in Peripheral Organs.
Published in:
PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0080705
By:
- Baptista, Marco A. S.;
- Dave, Kuldip D.;
- Frasier, Mark A.;
- Sherer, Todd B.;
- Greeley, Melanie;
- Beck, Melissa J.;
- Varsho, Julie S.;
- Parker, George A.;
- Moore, Cindy;
- Churchill, Madeline J.;
- Meshul, Charles K.;
- Fiske, Brian K.
Publication type:
Article
Precision medicine for Parkinson’s disease: The subtyping challenge.
Published in:
Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.1064057
By:
- Frasier, Mark;
- Fiske, Brian K.;
- Sherer, Todd B.
Publication type:
Article
Fluoxetine treatment of prepubescent rats produces a selective functional reduction in the 5-HT<sub>2A</sub> receptor-mediated stimulation of oxytocin.
Published in:
Synapse, 2005, v. 58, n. 2, p. 102, doi. 10.1002/syn.20187
By:
- Landry, Michelle;
- Frasier, Mark;
- Chen, Zhuo;
- Van De Kar, Louis D.;
- Zhang, Yahong;
- Garcia, Francisca;
- Battaglia, George
Publication type:
Article
Parkinson's Disease Biomarkers: Resources for Discovery and Validation.
Published in:
Neuropsychopharmacology, 2014, v. 39, n. 1, p. 241, doi. 10.1038/npp.2013.246
By:
- Frasier, Mark;
- Kang, Un Jung
Publication type:
Article
Association of Cerebrospinal Fluid β-Amyloid 1-42, T-tau, P-tau<sub>181</sub>, and α-Synuclein Levels With Clinical Features of Drug-Naive Patients With Early Parkinson Disease.
Published in:
JAMA Neurology, 2013, v. 70, n. 10, p. 1277, doi. 10.1001/jamaneurol.2013.3861
By:
- Ju-Hee Kang;
- Irwin, David J.;
- Chen-Plotkin, Alice S.;
- Siderowf, Andrew;
- Caspell, Chelsea;
- Coffey, Christopher S.;
- Waligórska, Teresa;
- Taylor, Peggy;
- Pan, Sarah;
- Frasier, Mark;
- Marek, Kenneth;
- Kieburtz, Karl;
- Jennings, Danna;
- Simuni, Tanya;
- Tanner, Caroline M.;
- Singleton, Andrew;
- Toga, Arthur W.;
- Chowdhury, Sohini;
- Mollenhauer, Brit;
- Trojanowski, John Q.
Publication type:
Article
Innovative Approaches for Slowing Disease Progression in Parkinson's Disease: Takeaways from the 14th Annual International Society for Central Nervous System Clinical Trials and Methodology Scientific Meeting.
Published in:
Innovations in Clinical Neuroscience, 2020, v. 17, n. 1/3, p. 14
By:
- JAVIDNIA, MONICA;
- FRASIER, MARK;
- SHOULSON, IRA;
- TURKOZ, IBRAHIM;
- BUDUR, KUMAR
Publication type:
Article
Deep Learning for Daily Monitoring of Parkinson's Disease Outside the Clinic Using Wearable Sensors.
Published in:
Sensors (14248220), 2022, v. 22, n. 18, p. 6831, doi. 10.3390/s22186831
By:
- Atri, Roozbeh;
- Urban, Kevin;
- Marebwa, Barbara;
- Simuni, Tanya;
- Tanner, Caroline;
- Siderowf, Andrew;
- Frasier, Mark;
- Haas, Magali;
- Lancashire, Lee
Publication type:
Article
Finding useful biomarkers for Parkinson's disease.
Published in:
Science Translational Medicine, 2018, v. 10, n. 454, p. 1, doi. 10.1126/scitranslmed.aam6003
By:
- Chen-Plotkin, Alice S.;
- Albin, Roger;
- Alcalay, Roy;
- Babcock, Debra;
- Bajaj, Vikram;
- Bowman, Dubois;
- Buko, Alex;
- Cedarbaum, Jesse;
- Chelsky, Daniel;
- Cookson, Mark R.;
- Dawson, Ted M.;
- Dewey, Richard;
- Foroud, Tatiana;
- Frasier, Mark;
- German, Dwight;
- Gwinn, Katrina;
- Huang, Xuemei;
- Kopil, Catherine;
- Kremer, Thomas;
- Lasch, Shirley
Publication type:
Article
Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson's disease.
Published in:
2017
By:
- Eidson, Lori;
- Kannarkat, George;
- Barnum, Christopher;
- Chang, Jianjun;
- Chung, Jaegwon;
- Caspell-Garcia, Chelsea;
- Taylor, Peggy;
- Mollenhauer, Brit;
- Schlossmacher, Michael;
- Ereshefsky, Larry;
- Yen, Mark;
- Kopil, Catherine;
- Frasier, Mark;
- Marek, Kenneth;
- Hertzberg, Vicki;
- Tansey, Malú;
- Eidson, Lori N;
- Kannarkat, George T;
- Barnum, Christopher J;
- Schlossmacher, Michael G
Publication type:
journal article
Differences in the Presentation and Progression of Parkinson's Disease by Sex.
Published in:
2021
By:
- Iwaki, Hirotaka;
- Blauwendraat, Cornelis;
- Leonard, Hampton L.;
- Makarious, Mary B.;
- Kim, Jonggeol J.;
- Liu, Ganqiang;
- Maple‐Grødem, Jodi;
- Corvol, Jean‐Christophe;
- Pihlstrøm, Lasse;
- Nimwegen, Marlies;
- Smolensky, Luba;
- Amondikar, Ninad;
- Hutten, Samantha J.;
- Frasier, Mark;
- Nguyen, Khanh‐Dung H.;
- Rick, Jacqueline;
- Eberly, Shirley;
- Faghri, Faraz;
- Auinger, Peggy;
- Scott, Kirsten M.
Publication type:
journal article
Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson's Disease Progression.
Published in:
Movement Disorders, 2020, v. 35, n. 11, p. 1999, doi. 10.1002/mds.28206
By:
- Mollenhauer, Brit;
- Dakna, Mohammed;
- Kruse, Niels;
- Galasko, Douglas;
- Foroud, Tatiana;
- Zetterberg, Henrik;
- Schade, Sebastian;
- Gera, Roland G.;
- Wang, Wenting;
- Gao, Feng;
- Frasier, Mark;
- Chahine, Lana M.;
- Coffey, Christopher S.;
- Singleton, Andrew B.;
- Simuni, Tanya;
- Weintraub, Daniel;
- Seibyl, John;
- Toga, Arthur W.;
- Tanner, Caroline M.;
- Kieburtz, Karl
Publication type:
Article
Longitudinal analyses of cerebrospinal fluid α-Synuclein in prodromal and early Parkinson's disease.
Published in:
2019
By:
- Mollenhauer, Brit;
- Caspell‐Garcia, Chelsea J.;
- Coffey, Christopher S.;
- Taylor, Peggy;
- Singleton, Andy;
- Shaw, Leslie M.;
- Trojanowski, John Q.;
- Frasier, Mark;
- Simuni, Tanya;
- Iranzo, Alex;
- Oertel, Wolfgang;
- Siderowf, Andrew;
- Weintraub, Daniel;
- Seibyl, John;
- Toga, Arthur W.;
- Tanner, Caroline M.;
- Kieburtz, Karl;
- Chahine, Lana M.;
- Marek, Kenneth;
- Galasko, Douglas
Publication type:
journal article
CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study.
Published in:
Acta Neuropathologica, 2016, v. 131, n. 6, p. 935, doi. 10.1007/s00401-016-1552-2
By:
- Kang, Ju-Hee;
- Mollenhauer, Brit;
- Coffey, Christopher;
- Toledo, Jon;
- Weintraub, Daniel;
- Galasko, Douglas;
- Irwin, David;
- Van Deerlin, Vivianna;
- Chen-Plotkin, Alice;
- Caspell-Garcia, Chelsea;
- Waligórska, Teresa;
- Taylor, Peggy;
- Shah, Nirali;
- Pan, Sarah;
- Zero, Pawel;
- Frasier, Mark;
- Marek, Kenneth;
- Kieburtz, Karl;
- Jennings, Danna;
- Tanner, Caroline
Publication type:
Article
Cerebrospinal fluid, plasma, and saliva in the BioFIND study: Relationships among biomarkers and Parkinson's disease Features.
Published in:
2018
By:
- Goldman, Jennifer G.;
- Andrews, Howard;
- Amara, Amy;
- Naito, Anna;
- Alcalay, Roy N.;
- Shaw, Leslie M.;
- Taylor, Peggy;
- Xie, Tao;
- Tuite, Paul;
- Henchcliffe, Claire;
- Hogarth, Penelope;
- Frank, Samuel;
- Saint‐Hilaire, Marie‐Helene;
- Frasier, Mark;
- Arnedo, Vanessa;
- Reimer, Alyssa N.;
- Sutherland, Margaret;
- Swanson‐Fischer, Christine;
- Gwinn, Katrina;
- The Fox Investigation of New Biomarker Discovery
Publication type:
journal article
A user's guide for α-synuclein biomarker studies in biological fluids: Perianalytical considerations.
Published in:
2017
By:
- Mollenhauer, Brit;
- Batrla, Richard;
- El‐Agnaf, Omar;
- Galasko, Douglas R.;
- Lashuel, Hilal A.;
- Merchant, Kalpana M.;
- Shaw, Lesley M.;
- Selkoe, Dennis J.;
- Umek, Robert;
- Vanderstichele, Hugo;
- Zetterberg, Henrik;
- Zhang, Jing;
- Caspell‐Garcia, Chelsea;
- Coffey, Chris;
- Hutten, Samantha J.;
- Frasier, Mark;
- Taylor, Peggy;
- El-Agnaf, Omar;
- Caspell-Garcia, Chelsea;
- Investigating Synuclein Consortium of the Michael J. Fox Foundation for Parkinson's Research
Publication type:
journal article
The BioFIND study: Characteristics of a clinically typical Parkinson's disease biomarker cohort.
Published in:
2016
By:
- Kang, Un Jung;
- Goldman, Jennifer G.;
- Alcalay, Roy N.;
- Xie, Tao;
- Tuite, Paul;
- Henchcliffe, Claire;
- Hogarth, Penelope;
- Amara, Amy W.;
- Frank, Samuel;
- Rudolph, Alice;
- Casaceli, Cynthia;
- Andrews, Howard;
- Gwinn, Katrina;
- Sutherland, Margaret;
- Kopil, Catherine;
- Vincent, Lona;
- Frasier, Mark
Publication type:
journal article
Funding of Parkinson research from industry and US federal and foundation sources.
Published in:
Movement Disorders, 2009, v. 24, n. 5, p. 731, doi. 10.1002/mds.22446
By:
- Dorsey, E. Ray;
- Thompson, Joel P.;
- Frasier, Mark;
- Sherer, Todd;
- Fiske, Brian;
- Nicholson, Sean;
- Johnston, S. Claiborne;
- Holloway, Robert G.;
- Moses, Hamilton
Publication type:
Article

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