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Antibacterial Aminoglycosides with a Modified Mode of Binding to the Ribosomal-RNA Decoding Site.
- Published in:
- Angewandte Chemie International Edition, 2007, v. 46, n. 17, p. 2971, doi. 10.1002/anie.200790074
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- Article
Antibacterial Aminoglycosides with a Modified Mode of Binding to the Ribosomal-RNA Decoding SiteWe thank the NSERC and the Institut Universitaire de France for financial assistance provided to S.H. and E.W., respectively. Thanks are due to Lisa M. Risen for transcription/translation and MIC assays, and Dr. Kristen A. Sannes-Lowery for the KD determinations. We acknowledge the European Synchrotron Radiation Facility for provision of synchrotron radiation facilities, and we thank Stéphanie Monaco and Joanne McCarthy for assistance with the use of beamlines ID14-2 and ID14-4.
- Published in:
- Angewandte Chemie, 2004, v. 116, n. 48, p. 6903
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- Article
Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site Complexed with ApramycinJ.K. is supported by the Japan Society for the Promotion of Science. We are grateful to Dr. B. Masquida, Dr. A. C. Vaiana, Dr. P. Auffinger, and Prof. P. S. Ho for helpful discussions and suggestions. We thank the European Synchrotron Radiation Facility for the use of their facilities and acknowledge the staff of beamline ID14-4.
- Published in:
- Angewandte Chemie, 2006, v. 118, n. 20, p. 3388, doi. 10.1002/ange.200600354
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- Article
Crystal Structure of the Bacterial Ribosomal Decoding Site Complexed with a Synthetic Doubly Functionalized Paromomycin Derivative: a New Specific Binding Mode to an A-Minor Motif Enhances in vitro Antibacterial Activity.
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- ChemMedChem, 2007, v. 2, n. 11, p. 1631, doi. 10.1002/cmdc.200700113
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- Article
Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding.
- Published in:
- Nucleic Acids Research, 2005, v. 33, n. 17, p. 5677, doi. 10.1093/nar/gki862
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- Publication type:
- Article
Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site Complexed with ApramycinJ.K. is supported by the Japan Society for the Promotion of Science. We are grateful to Dr. B. Masquida, Dr. A. C. Vaiana, Dr. P. Auffinger, and Prof. P. S. Ho for helpful discussions and suggestions. We thank the European Synchrotron Radiation Facility for the use of their facilities and acknowledge the staff of beamline ID14-4.
- Published in:
- Angewandte Chemie International Edition, 2006, v. 45, n. 20, p. 3310, doi. 10.1002/anie.200600354
- By:
- Publication type:
- Article
Antibacterial Aminoglycosides with a Modified Mode of Binding to the Ribosomal-RNA Decoding SiteWe thank the NSERC and the Institut Universitaire de France for financial assistance provided to S.H. and E.W., respectively. Thanks are due to Lisa M. Risen for transcription/translation and MIC assays, and Dr. Kristen A. Sannes-Lowery for the KD determinations. We acknowledge the European Synchrotron Radiation Facility for provision of synchrotron radiation facilities, and we thank Stéphanie Monaco and Joanne McCarthy for assistance with the use of beamlines ID14-2 and ID14-4.
- Published in:
- Angewandte Chemie International Edition, 2004, v. 43, n. 48, p. 6735
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- Publication type:
- Article