Works by Frahm, Nicole

Results: 47

Antibody and cellular responses to HIV vaccine regimens with DNA plasmid as compared with ALVAC priming: An analysis of two randomized controlled trials.

Published in:

PLoS Medicine, 2020, v. 17, n. 5, p. 1, doi. 10.1371/journal.pmed.1003117

By:

Moodie, Zoe;
Walsh, Stephen R.;
Laher, Fatima;
Maganga, Lucas;
Herce, Michael E.;
Naidoo, Sarita;
Hosseinipour, Mina C.;
Innes, Craig;
Bekker, Linda-Gail;
Grunenberg, Nicole;
Mann, Philipp;
Yu, Chenchen;
deCamp, Allan C.;
Miner, Maurine D.;
Yates, Nicole L.;
Heptinstall, Jack;
Mkhize, Nonhlanhla N.;
Dintwe, One;
Frahm, Nicole;
Cohen, Kristen W.

Publication type:

Article

Antibody and cellular responses to HIV vaccine regimens with DNA plasmid as compared with ALVAC priming: An analysis of two randomized controlled trials.

Published in:

2020

By:

Moodie, Zoe;
Walsh, Stephen R;
Laher, Fatima;
Maganga, Lucas;
Herce, Michael E;
Naidoo, Sarita;
Hosseinipour, Mina C;
Innes, Craig;
Bekker, Linda-Gail;
Grunenberg, Nicole;
Mann, Philipp;
Yu, Chenchen;
deCamp, Allan C;
Miner, Maurine D;
Yates, Nicole L;
Heptinstall, Jack;
Mkhize, Nonhlanhla N;
Dintwe, One;
Frahm, Nicole;
Cohen, Kristen W

Publication type:

journal article

Extensive HLA class I allele promiscuity among viral CTL epitopes.

Published in:

European Journal of Immunology, 2007, v. 37, n. 9, p. 2419, doi. 10.1002/eji.200737365

By:

Frahm, Nicole;
Yusim, Karina;
Suscovich, Todd J.;
Adams, Sharon;
Sidney, John;
Hraber, Peter;
Hewitt, Hannah S.;
Linde, Caitlyn H.;
Kavanagh, Daniel G.;
Woodberry, Tonia;
Henry, Leah M.;
Faircloth, Kellie;
Listgarten, Jennifer;
Kadie, Carl;
Jojic, Nebojsa;
Sango, Kaori;
Brown, Nancy V.;
Pae, Eunice;
Zaman, M. Tauheed;
Bihl, Florian

Publication type:

Article

The defined attenuated Listeria monocytogenes Δmpl2 mutant is an effective oral vaccine carrier to trigger a long-lasting immune response against a mouse fibrosarcoma.

Published in:

European Journal of Immunology, 1997, v. 27, n. 6, p. 1570, doi. 10.1002/eji.1830270637

By:

Paglia, Paola;
Arioli, Ivano;
Frahm, Nicole;
Chakraborty, Trinad;
Colombo, Mario P.;
Guzmàn, Carlos A.

Publication type:

Article

Higher T-Cell Responses Induced by DNA/rAd5 HIV-1 Preventive Vaccine Are Associated With Lower HIV-1 Infection Risk in an Efficacy Trial.

Published in:

2017

By:

Janes, Holly E.;
Cohen, Kristen W.;
Frahm, Nicole;
De Rosa, Stephen C.;
Sanchez, Brittany;
Hural, John;
Magaret, Craig A.;
Karuna, Shelly;
Bentley, Carter;
Gottardo, Raphael;
Finak, Greg;
Grove, Douglas;
Shen, Mingchao;
Graham, Barney S.;
Koup, Richard A.;
Mulligan, Mark J.;
Koblin, Beryl;
Buchbinder, Susan P.;
Keefer, Michael C.;
Adams, Elizabeth

Publication type:

journal article

Lower Viral Loads and Slower CD4+ T-Cell Count Decline in MRKAd5 HIV-1 Vaccinees Expressing Disease-Susceptible HLA-B*58:02.

Published in:

2016

By:

Leitman, Ellen M.;
Hurst, Jacob;
Masahiko Mori;
Kublin, James;
Thumbi Ndung'u;
Walker, Bruce D.;
Carlson, Jonathan;
Gray, Glenda E.;
Matthews, Philippa C.;
Frahm, Nicole;
Goulder, Philip J. R.;
Mori, Masahiko;
Ndung'u, Thumbi

Publication type:

journal article

Vaccination With Heterologous HIV-1 Envelope Sequences and Heterologous Adenovirus Vectors Increases T-Cell Responses to Conserved Regions: HVTN 083.

Published in:

2016

By:

Walsh, Stephen R.;
Moodie, Zoe;
Fiore-Gartland, Andrew J.;
Morgan, Cecilia;
Wilck, Marissa B.;
Hammer, Scott M.;
Buchbinder, Susan P.;
Kalams, Spyros A.;
Goepfert, Paul A.;
Mulligan, Mark J.;
Keefer, Michael C.;
Baden, Lindsey R.;
Swann, Edith M.;
Grant, Shannon;
Ahmed, Hasan;
Fusheng Li;
Hertz, Tomer;
Self, Steven G.;
Friedrich, David;
Frahm, Nicole

Publication type:

journal article

Vaccine-Induced Gag-Specific T Cells Are Associated With Reduced Viremia After HIV-1 Infection.

Published in:

Journal of Infectious Diseases, 2013, v. 208, n. 8, p. 1231, doi. 10.1093/infdis/jit322

By:

Janes, Holly;
Friedrich, David P.;
Krambrink, Amy;
Smith, Rebecca J.;
Kallas, Esper G.;
Horton, Helen;
Casimiro, Danilo R.;
Carrington, Mary;
Geraghty, Daniel E.;
Gilbert, Peter B.;
McElrath, M. Juliana;
Frahm, Nicole

Publication type:

Article

Characterization of Humoral and Cellular Immune Responses Elicited by a Recombinant Adenovirus Serotype 26 HIV-1 Env Vaccine in Healthy Adults (IPCAVD 001).

Published in:

Journal of Infectious Diseases, 2013, v. 207, n. 2, p. 248, doi. 10.1093/infdis/jis671

By:

Barouch, Dan H.;
Liu, Jinyan;
Peter, Lauren;
Abbink, Peter;
Iampietro, M. Justin;
Cheung, Ann;
Alter, Galit;
Chung, Amy;
Dugast, Anne-Sophie;
Frahm, Nicole;
McElrath, M. Juliana;
Wenschuh, Holger;
Reimer, Ulf;
Seaman, Michael S.;
Pau, Maria G.;
Weijtens, Mo;
Goudsmit, Jaap;
Walsh, Stephen R.;
Dolin, Raphael;
Baden, Lindsey R.

Publication type:

Article

Host Genetic Determinants of T Cell Responses to the MRKAd5 HIV-1 gag/pol/nef Vaccine in the Step Trial.

Published in:

Journal of Infectious Diseases, 2011, v. 203, n. 6, p. 773, doi. 10.1093/infdis/jiq125

By:

Fellay, Jacques;
Frahm, Nicole;
Shianna, Kevin V.;
Cirulli, Elizabeth T.;
Casimiro, Danilo R.;
Robertson, Michael N.;
Haynes, Barton F.;
Geraghty, Daniel E.;
McElrath, M. Juliana;
Goldstein, David B.

Publication type:

Article

Simultaneous assessment of cytotoxic T lymphocyte responses against multiple viral infections by combined usage of optimal epitope matrices, anti- CD3 mAb T-cell expansion and "RecycleSpot.".

Published in:

Journal of Translational Medicine, 2005, v. 3, p. 20, doi. 10.1186/1479-5876-3-20

By:

Bihl, Florian K.;
Loggi, Elisabetta;
Chisholm III, John V.;
Hewitt, Hannah S.;
Henry, Leah M.;
Linde, Caitlyn;
Suscovich, Todd J.;
Wong, Johnson T.;
Frahm, Nicole;
Andreone, Pietro;
Brander, Christian

Publication type:

Article

Sequence and vector shapes vaccine induced antibody effector functions in HIV vaccine trials.

Published in:

PLoS Pathogens, 2021, v. 17, n. 11, p. 1, doi. 10.1371/journal.ppat.1010016

By:

Fischinger, Stephanie;
Cizmeci, Deniz;
Deng, Davy;
Grant, Shannon P.;
Frahm, Nicole;
McElrath, Julie;
Fuchs, Jonathan;
Bart, Pierre-Alexandre;
Pantaleo, Giuseppe;
Keefer, Michael;
O. Hahn, William;
Rouphael, Nadine;
Churchyard, Gavin;
Moodie, Zoe;
Donastorg, Yeycy;
Streeck, Hendrik;
Alter, Galit

Publication type:

Article

HLA class I supertypes: a revised and updated classification.

Published in:

BMC Immunology, 2008, v. 9, p. 1, doi. 10.1186/1471-2172-9-1

By:

Sidney, John;
Peters, Bjoern;
Frahm, Nicole;
Brander, Christian;
Sette, Alessandro

Publication type:

Article

A Statistical Framework for Modeling HLA-Dependent T Cell Response Data.

Published in:

PLoS Computational Biology, 2007, v. 3, n. 10, p. e188, doi. 10.1371/journal.pcbi.0030188

By:

Listgarten, Jennifer;
Frahm, Nicole;
Kadie, Carl;
Brander, Christian;
Heckerman, David

Publication type:

Article

Listeriolysin O: cholesterol inhibits cytolysis but not binding to cellular membranes.

Published in:

Molecular Microbiology, 1998, v. 28, n. 6, p. 1081, doi. 10.1046/j.1365-2958.1998.00858.x

By:

Jacobs, Thomas;
Darji, Ayub;
Frahm, Nicole;
Rohde, Manfred;
Wehland, Jürgen;
Chakraborty, Trinad;
Weiss, Siegfried

Publication type:

Article

Comparative Immunogenicity of HIV-1 gp140 Vaccine Delivered by Parenteral, and Mucosal Routes in Female Volunteers; MUCOVAC2, A Randomized Two Centre Study.

Published in:

PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0152038

By:

Cosgrove, Catherine A.;
Lacey, Charles J.;
Cope, Alethea V.;
Bartolf, Angela;
Morris, Georgina;
Yan, Celine;
Baden, Susan;
Cole, Tom;
Carter, Darrick;
Brodnicki, Elizabeth;
Shen, Xiaoying;
Joseph, Sarah;
DeRosa, Stephen C.;
Peng, Lili;
Yu, Xuesong;
Ferrari, Guido;
Seaman, Mike;
Montefiori, David C.;
Frahm, Nicole;
Tomaras, Georgia D.

Publication type:

Article

Pooled-Peptide Epitope Mapping Strategies Are Efficient and Highly Sensitive: An Evaluation of Methods for Identifying Human T Cell Epitope Specificities in Large-Scale HIV Vaccine Efficacy Trials.

Published in:

PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0147812

By:

Fiore-Gartland, Andrew;
Manso, Bryce A.;
Friedrich, David P.;
Gabriel, Erin E.;
Finak, Greg;
Moodie, Zoe;
Hertz, Tomer;
De Rosa, Stephen C.;
Frahm, Nicole;
Gilbert, Peter B.;
McElrath, M. Juliana

Publication type:

Article

Impact of Select Immunologic and Virologic Biomarkers on CD4 Cell Count Decrease in Patients with Chronic HIV-1 Subtype C Infection: Results from Sinikithemba Cohort, Durban, South Africa.

Published in:

Clinical Infectious Diseases, 2009, v. 49, n. 6, p. 956, doi. 10.1086/605503

By:

Brumme, Zabrina;
Bingxia Wang;
Nair, Kriebashne;
Brumme, Chanson;
de Pierres, Chantal;
Reddy, Shabashini;
Julg, Boris;
Moodley, Eshia;
Thobakgale, Christina;
Zhigang Lu;
van der Stok, Mary;
Bishop, Karen;
Mncube, Zenele;
Chonco, Fundisiwe;
Yuki, Yuko;
Frahm, Nicole;
Brander, Christian;
Carrington, Mary;
Freedberg,, Kenneth;
Kiepiela, Photini

Publication type:

Article

CXCR3 enables recruitment and site-specific bystander activation of memory CD8<sup>+</sup> T cells.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-12980-2

By:

Maurice, Nicholas J.;
McElrath, M. Juliana;
Andersen-Nissen, Erica;
Frahm, Nicole;
Prlic, Martin

Publication type:

Article

Contribution of Immunological and Virological Factors to Extremely Severe Primary HIV Type 1 Infection.

Published in:

Clinical Infectious Diseases, 2009, v. 48, n. 2, p. 229, doi. 10.1086/595704

By:

Dalmau, Judith;
Puertas, Maria Carmen;
Azuara, Marta;
Mariño, Ana;
Frahm, Nicole;
Mothe, Beatriz;
Izquierdo-Useros, Nuria;
Buzón, Maria José;
Paredes, Roger;
Matas, Lourdes;
Allen, Todd M.;
Brander, Christian;
Rodrigo, Carlos;
Clotet, Bonaventura;
Martinez-Picado, Javier

Publication type:

Article

HIV-1 infections with multiple founders are associated with higher viral loads than infections with single founders.

Published in:

Nature Medicine, 2015, v. 21, n. 10, p. 1139, doi. 10.1038/nm.3932

By:

Janes, Holly;
Herbeck, Joshua T;
Tovanabutra, Sodsai;
Thomas, Rasmi;
Frahm, Nicole;
Duerr, Ann;
Hural, John;
Corey, Lawrence;
Self, Steve G;
Buchbinder, Susan P;
McElrath, M Juliana;
O'Connell, Robert J;
Paris, Robert M;
Rerks-Ngarm, Supachai;
Nitayaphan, Sorachai;
Pitisuttihum, Punnee;
Kaewkungwal, Jaranit;
Robb, Merlin L;
Michael, Nelson L;
Mullins, James I

Publication type:

Article

Genetic impact of vaccination on breakthrough HIV-1 sequences from the STEP trial.

Published in:

Nature Medicine, 2011, v. 17, n. 3, p. 366, doi. 10.1038/nm.2316

By:

Rolland, Morgane;
Tovanabutra, Sodsai;
deCamp, Allan C.;
Frahm, Nicole;
Gilbert, Peter B.;
Sanders-Buell, Eric;
Heath, Laura;
Magaret, Craig A.;
Bose, Meera;
Bradfield, Andrea;
O'Sullivan, Annemarie;
Crossler, Jacqueline;
Jones, Teresa;
Nau, Marty;
Kim Wong;
Hong Zhao;
Raugi, Dana N.;
Sorensen, Stephanie;
Stoddard, Julia N.;
Maust, Brandon S.

Publication type:

Article

Nonlinear Calibration Model Choice between the Four and Five-Parameter Logistic Models.

Published in:

Journal of Biopharmaceutical Statistics, 2015, v. 25, n. 5, p. 972, doi. 10.1080/10543406.2014.920345

By:

Cumberland, William N.;
Fong, Youyi;
Yu, Xuesong;
Defawe, Olivier;
Frahm, Nicole;
De Rosa, Stephen

Publication type:

Article

Immunogenicity of a novel Clade B HIV-1 vaccine combination: Results of phase 1 randomized placebo controlled trial of an HIV-1 GM-CSF-expressing DNA prime with a modified vaccinia Ankara vaccine boost in healthy HIV-1 uninfected adults.

Published in:

PLoS ONE, 2017, v. 12, n. 7, p. 1, doi. 10.1371/journal.pone.0179597

By:

Buchbinder, Susan P.;
Grunenberg, Nicole A.;
Sanchez, Brittany J.;
Seaton, Kelly E.;
Ferrari, Guido;
Moody, M. Anthony;
Frahm, Nicole;
Montefiori, David C.;
Hay, Christine M.;
Goepfert, Paul A.;
Baden, Lindsey R.;
Robinson, Harriet L.;
Yu, Xuesong;
Gilbert, Peter B.;
McElrath, M. Juliana;
Huang, Yunda;
Tomaras, Georgia D.;
null, null

Publication type:

Article

Current views on the potential for development of a HIV vaccine.

Published in:

Expert Opinion on Biological Therapy, 2017, v. 17, n. 3, p. 295, doi. 10.1080/14712598.2017.1282457

By:

Cohen, Kristen W.;
Frahm, Nicole

Publication type:

Article

COMPASS identifies T-cell subsets correlated with clinical outcomes.

Published in:

Nature Biotechnology, 2015, v. 33, n. 6, p. 610, doi. 10.1038/nbt.3187

By:

Lin, Lin;
Finak, Greg;
Ushey, Kevin;
Seshadri, Chetan;
Hawn, Thomas R;
Frahm, Nicole;
Scriba, Thomas J;
Mahomed, Hassan;
Hanekom, Willem;
Bart, Pierre-Alexandre;
Pantaleo, Giuseppe;
Tomaras, Georgia D;
Rerks-Ngarm, Supachai;
Kaewkungwal, Jaranit;
Nitayaphan, Sorachai;
Pitisuttithum, Punnee;
Michael, Nelson L;
Kim, Jerome H;
Robb, Merlin L;
O'Connell, Robert J

Publication type:

Article

First-in-Human Evaluation of the Safety and Immunogenicity of a Recombinant Vesicular Stomatitis Virus Human Immunodeficiency Virus-1 gag Vaccine (HVTN 090).

Published in:

Open Forum Infectious Diseases, 2015, v. 2, n. 3, p. 1, doi. 10.1093/ofid/ofv082

By:

Fuchs, Jonathan D.;
Frank, Ian;
Elizaga, Marnie L.;
Allen, Mary;
Frahm, Nicole;
Kochar, Nidhi;
Sue Li;
Edupuganti, Srilatha;
Kalams, Spyros A.;
Tomaras, Georgia D.;
Sheets, Rebecca;
Pensiero, Michael;
Tremblay, Marc A.;
Higgins, Terry J.;
Latham, Theresa;
Egan, Michael A.;
Clarke, David K.;
Eldridge, John H.

Publication type:

Article

T cell receptor cross-recognition of an HIV-1 CD8+ T cell epitope presented by closely related alleles from the HLA-A3 superfamily.

Published in:

International Immunology, 2006, v. 18, n. 7, p. 1179, doi. 10.1093/intimm/dxl052

By:

Mathias Lichterfeld;
Katie L. Williams;
Stanley K. Mui;
Shivani S. Shah;
Bianca R. Mothe;
Alessandro Sette;
Arthur Kim;
Mary N. Johnston;
Nicole Burgett;
Nicole Frahm;
Daniel Cohen;
Christian Brander;
Eric S. Rosenberg;
Bruce D. Walker;
Marcus Altfeld;
Xu G. Yu

Publication type:

Article

Identification of Effective Subdominant Anti-HIV-1 CD8+ T Cells Within Entire Post-infection and Post-vaccination Immune Responses.

Published in:

PLoS Pathogens, 2015, v. 11, n. 2, p. 1, doi. 10.1371/journal.ppat.1004658

By:

Hancock, Gemma;
Yang, Hongbing;
Yorke, Elisabeth;
Wainwright, Emma;
Bourne, Victoria;
Frisbee, Alyse;
Payne, Tamika L.;
Berrong, Mark;
Ferrari, Guido;
Chopera, Denis;
Hanke, Tomas;
Mothe, Beatriz;
Brander, Christian;
McElrath, M. Juliana;
McMichael, Andrew;
Goonetilleke, Nilu;
Tomaras, Georgia D.;
Frahm, Nicole;
Dorrell, Lucy

Publication type:

Article

HIV-1 Vaccine-Induced T-Cell Reponses Cluster in Epitope Hotspots that Differ from Those Induced in Natural Infection with HIV-1.

Published in:

PLoS Pathogens, 2013, v. 9, n. 6, p. 1, doi. 10.1371/journal.ppat.1003404

By:

Hertz, Tomer;
Ahmed, Hasan;
Friedrich, David P.;
Casimiro, Danilo R.;
Self, Steven G.;
Corey, Lawrence;
McElrath, M. Juliana;
Buchbinder, Susan;
Horton, Helen;
Frahm, Nicole;
Robertson, Michael N.;
Graham, Barney S.;
Gilbert, Peter

Publication type:

Article

Trivalent Adenovirus Type 5 HIV Recombinant Vaccine Primes for Modest Cytotoxic Capacity That Is Greatest in Humans with Protective HLA Class I Alleles.

Published in:

PLoS Pathogens, 2011, v. 7, n. 2, p. 1, doi. 10.1371/journal.ppat.1002002

By:

Migueles, Stephen A.;
Rood, Julia E.;
Berkley, Amy M.;
Guo, Tiffany;
Mendoza, Daniel;
Patamawenu, Andy;
Hallahan, Claire W.;
Cogliano, Nancy A.;
Frahm, Nicole;
Duerr, Ann;
McElrath, M. Juliana;
Connors, Mark

Publication type:

Article

Evidence of Differential HLA Class I-Mediated Viral Evolution in Functional and Accessory/Regulatory Genes of HIV-1.

Published in:

PLoS Pathogens, 2007, v. 3, n. 7, p. e94, doi. 10.1371/journal.ppat.0030094

By:

Brumme, Zabrina L.;
Brumme, Chanson J.;
Heckerman, David;
Korber, Bette T.;
Daniels, Marcus;
Carlson, Jonathan;
Kadie, Carl;
Bhattacharya, Tanmoy;
Chui, Celia;
Szinger, James;
Mo, Theresa;
Hogg, Robert S.;
Montaner, Julio S. G.;
Frahm, Nicole;
Brander, Christian;
Walker, Bruce D.;
Harrigan, P. Richard

Publication type:

Article

Safety and Immunogenicity of Novel Adenovirus Type 26- and Modified Vaccinia Ankara-Vectored Ebola Vaccines: A Randomized Clinical Trial.

Published in:

2016

By:

Milligan, Iain D.;
Gibani, Malick M.;
Sewell, Richard;
Clutterbuck, Elizabeth A.;
Campbell, Danielle;
Plested, Emma;
Nuthall, Elizabeth;
Voysey, Merryn;
Silva-Reyes, Laura;
Juliana McElrath, M.;
De Rosa, Stephen C.;
Frahm, Nicole;
Cohen, Kristen W.;
Shukarev, Georgi;
Orzabal, Nicola;
Duijnhoven, Wilbert van;
Truyers, Carla;
Bachmayer, Nora;
Splinter, Daniel;
Samy, Nathaly

Publication type:

journal article

Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial Reveals an Association of Nonspecific Interferon-γ Secretion with Increased HIV-1 Infection Risk: A Cohort-Based Modeling Study.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0108631

By:

Huang, Yunda;
Duerr, Ann;
Frahm, Nicole;
Zhang, Lily;
Moodie, Zoe;
De Rosa, Steve;
McElrath, M. Juliana;
Gilbert, Peter B.

Publication type:

Article

MRKAd5 HIV-1 Gag/Pol/Nef Vaccine-Induced T-Cell Responses Inadequately Predict Distance of Breakthrough HIV-1 Sequences to the Vaccine or Viral Load.

Published in:

PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043396

By:

Janes, Holly;
Frahm, Nicole;
DeCamp, Allan;
Rolland, Morgane;
Gabriel, Erin;
Wolfson, Julian;
Hertz, Tomer;
Kallas, Esper;
Goepfert, Paul;
Friedrich, David P.;
Corey, Lawrence;
Mullins, James I.;
McElrath, M. Juliana;
Gilbert, Peter;
Gray, Clive M.

Publication type:

Article

Increased Breadth and Depth of Cytotoxic T Lymphocytes Responses against HIV-1-B Nef by Inclusion of Epitope Variant Sequences.

Published in:

PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0017969

By:

Rolland, Morgane;
Frahm, Nicole;
Nickle, David C.;
Jojic, Nebojsa;
Wenjie Deng;
Allen, Todd M.;
Brander, Christian;
Heckerman, David E.;
Mullins, James I.

Publication type:

Article

HLA-Associated Immune Escape Pathways in HIV-1 Subtype B Gag, Pol and Nef Proteins.

Published in:

PLoS ONE, 2009, v. 4, n. 8, p. 1, doi. 10.1371/journal.pone.0006687

By:

Brumme, Zabrina L.;
John, Mina;
Carlson, Jonathan M.;
Brumme, Chanson J.;
Chan, Dennison;
Brockman, Mark A.;
Swenson, Luke C.;
Tao, Iris;
Szeto, Sharon;
Rosato, Pamela;
Sela, Jennifer;
Kadie, Carl M.;
Frahm, Nicole;
Brander, Christian;
Haas, David W.;
Riddler, Sharon A.;
Haubrich, Richard;
Walker, Bruce D.;
Harrigan, P. Richard;
David Heckerman

Publication type:

Article

Safety and immune responses after a 12-month booster in healthy HIV-uninfected adults in HVTN 100 in South Africa: A randomized double-blind placebo-controlled trial of ALVAC-HIV (vCP2438) and bivalent subtype C gp120/MF59 vaccines.

Published in:

2020

By:

Laher, Fatima;
Moodie, Zoe;
Cohen, Kristen W.;
Grunenberg, Nicole;
Bekker, Linda-Gail;
Allen, Mary;
Frahm, Nicole;
Yates, Nicole L.;
Morris, Lynn;
Malahleha, Mookho;
Mngadi, Kathryn;
Daniels, Brodie;
Innes, Craig;
Saunders, Kevin;
Grant, Shannon;
Yu, Chenchen;
Gilbert, Peter B.;
Phogat, Sanjay;
DiazGranados, Carlos A.;
Koutsoukos, Marguerite

Publication type:

journal article

Assessment of the Safety and Immunogenicity of 2 Novel Vaccine Platforms for HIV-1 Prevention: A Randomized Trial.

Published in:

2016

By:

Baden, Lindsey R.;
Karita, Etienne;
Mutua, Gaudensia;
Bekker, Linda-Gail;
Gray, Glenda;
Page-Shipp, Liesl;
Walsh, Stephen R.;
Nyombayire, Julien;
Anzala, Omu;
Roux, Surita;
Laher, Fatima;
Innes, Craig;
Seaman, Michael S.;
Cohen, Yehuda Z.;
Peter, Lauren;
Frahm, Nicole;
McElrath, M. Juliana;
Hayes, Peter;
Swann, Edith;
Grunenberg, Nicole

Publication type:

journal article

Distinct susceptibility of HIV vaccine vector-induced CD4 T cells to HIV infection.

Published in:

PLoS Pathogens, 2018, v. 14, n. 2, p. 1, doi. 10.1371/journal.ppat.1006888

By:

Auclair, Sarah;
Liu, Fengliang;
Niu, Qingli;
Hou, Wei;
Churchyard, Gavin;
Morgan, Cecilia;
Frahm, Nicole;
Nitayaphan, Sorachai;
Pitisuthithum, Punnee;
Rerks-Ngarm, Supachai;
Kimata, Jason T.;
Soong, Lynn;
Franchini, Genoveffa;
Robb, Merlin;
Kim, Jerome;
Michael, Nelson;
Hu, Haitao

Publication type:

Article

Gene signature discovery and systematic validation across diverse clinical cohorts for TB prognosis and response to treatment.

Published in:

PLoS Computational Biology, 2023, v. 19, n. 7, p. 1, doi. 10.1371/journal.pcbi.1010770

By:

Vargas, Roger;
Abbott, Liam;
Bower, Daniel;
Frahm, Nicole;
Shaffer, Mike;
Yu, Wen-Han

Publication type:

Article

Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes.

Published in:

Nature Immunology, 2006, v. 7, n. 2, p. 173, doi. 10.1038/ni1281

By:

Frahm, Nicole;
Kiepiela, Photini;
Adams, Sharon;
Linde, Caitlyn H;
Hewitt, Hannah S;
Sango, Kaori;
Feeney, Margaret E;
Addo, Marylyn M;
Lichterfeld, Mathias;
Lahaie, Matthew P;
Pae, Eunice;
Wurcel, Alysse G;
Roach, Timothy;
St John, M Anne;
Altfeld, Marcus;
Marincola, Francesco M;
Moore, Corey;
Mallal, Simon;
Carrington, Mary;
Heckerman, David

Publication type:

Article

Vaccine-elicited Human T Cells Recognizing Conserved Protein Regions Inhibit HIV-1.

Published in:

Molecular Therapy, 2014, v. 22, n. 2, p. 464, doi. 10.1038/mt.2013.248

By:

Borthwick, Nicola;
Ahmed, Tina;
Ondondo, Beatrice;
Hayes, Peter;
Rose, Annie;
Ebrahimsa, Umar;
Hayton, Emma-Jo;
Black, Antony;
Bridgeman, Anne;
Rosario, Maximillian;
Hill, Adrian VS;
Berrie, Eleanor;
Moyle, Sarah;
Frahm, Nicole;
Cox, Josephine;
Colloca, Stefano;
Nicosia, Alfredo;
Gilmour, Jill;
McMichael, Andrew J;
Dorrell, Lucy

Publication type:

Article

Achieving intracellular cytokine staining assay concordance on two continents to assess HIV vaccine‐induced T‐cell responses.

Published in:

Journal of Leukocyte Biology, 2022, v. 112, n. 5, p. 1167, doi. 10.1002/JLB.5MA0522-668R

By:

Dintwe, One B.;
De Rosa, Stephen C.;
Huang, Yunda;
Flach, Britta S.;
Manso, Bryce;
Carter, Don;
Omar, Faatima Laher;
Schwedhelm, Katharine V.;
Yu, Chenchen;
Lu, Huiyin;
Morris, Daryl;
Kee, Jia Jin;
Voillet, Valentin;
Stirewalt, Michael;
Hural, John;
Moodie, Zoe;
Frahm, Nicole;
Cohen, Kristen W.;
McElrath, M. Juliana;
Andersen‐Nissen, Erica

Publication type:

Article

Differential Targeting and Shifts in the Immunodominance of Epstein-Barr Virus--Specific CD8 and CD4 T Cell Responses during Acute and Persistent Infection.

Published in:

Journal of Infectious Diseases, 2005, v. 192, n. 9, p. 1513, doi. 10.1086/491741

By:

Woodberry, Tonia;
Suscovich, Todd J.;
Henry, Leah M.;
Davis, Jennifer K.;
Frahm, Nicole;
Walker, Bruce D.;
Scadden, David T.;
Wang, Frederick;
Brander, Christian

Publication type:

Article

HIV-specific humoral responses benefit from stronger prime in phase Ib clinical trial.

Published in:

2014

By:

Bart, Pierre-Alexandre;
Yunda Huang;
Karuna, Shelly T.;
Chappuis, Samuel;
Gaillard, Julien;
Kochar, Nidhi;
Xiaoying Shen;
Allen, Mary A.;
Song Ding;
Hural, John;
Hua-Xin Liao;
Haynes, Barton F.;
Graham, Barney S.;
Gilbert, Peter B.;
McElrath, M. Juliana;
Monteiori, David C.;
Tomaras, Georgia D.;
Pantaleo, Giuseppe;
Frahm, Nicole;
Huang, Yunda

Publication type:

journal article

Human adenovirus-specific T cells modulate HIV-specific T cell responses to an Ad5-vectored HIV-1 vaccine.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 1, p. 359, doi. 10.1172/JCI60202

By:

Frahm, Nicole;
DeCamp, Allan C.;
Friedrich, David P.;
Carter, Donald K.;
Defawe, Olivier D.;
Kublin, James G.;
Casimiro, Danilo R.;
Duerr, Ann;
Robertson, Michael N.;
Buchbinder, Susan P.;
Yunda Huang;
Spies, Gregory A.;
De Rosa, Stephen C.;
McElrath, M. Juliana

Publication type:

Article