Works by Fraenkel, Ernest


Results: 51
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    Core transcriptional regulatory circuitry in human hepatocytes.

    Published in:
    Molecular Systems Biology, 2006, v. 2, n. 1, p. E1, doi. 10.1038/msb4100059
    By:
    • Odom, Duncan T;
    • Dowell, Robin D;
    • Jacobsen, Elizabeth S;
    • Nekludova, Lena;
    • Rolfe, P Alexander;
    • Danford, Timothy W;
    • Gifford, David K;
    • Fraenkel, Ernest;
    • Bell, Graeme I;
    • Young, Richard A
    Publication type:
    Article
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    Immortalized striatal precursor neurons from Huntington’s disease patient-derived iPS cells as a platform for target identification and screening for experimental therapeutics.

    Published in:
    Human Molecular Genetics, 2021, v. 30, n. 24, p. 2469, doi. 10.1093/hmg/ddab200
    By:
    • Akimov, Sergey S.;
    • Mali Jiang;
    • Kedaigle, Amanda J.;
    • Arbez, Nicolas;
    • Marque, Leonard O.;
    • Eddings, Chelsy R.;
    • Ranum, Paul T.;
    • Whelan, Emma;
    • Tang, Anthony;
    • Wang, Ronald;
    • DeVine, Lauren R.;
    • Talbot Jr., Conover C.;
    • Cole, Robert N.;
    • Ratovitski, Tamara;
    • Davidson, Beverly L.;
    • Fraenkel, Ernest;
    • Ross, Christopher A.
    Publication type:
    Article
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    Intratumoral drug-releasing microdevices allow in situ high-throughput pharmaco phenotyping in patients with gliomas.

    Published in:
    Science Translational Medicine, 2023, v. 15, n. 712, p. 1, doi. 10.1126/scitranslmed.adi0069
    By:
    • Peruzzi, Pierpaolo;
    • Dominas, Christine;
    • Fell, Geoffrey;
    • Bernstock, Joshua D.;
    • Blitz, Sarah;
    • Mazzetti, Debora;
    • Zdioruk, Mykola;
    • Dawood, Hassan Y.;
    • Triggs, Daniel V.;
    • Ahn, Sebastian W.;
    • Bhagavatula, Sharath K.;
    • Davidson, Shawn M.;
    • Tatarova, Zuzana;
    • Pannell, Michael;
    • Truman, Kyla;
    • Ball, Anna;
    • Gold, Maxwell P.;
    • Pister, Veronika;
    • Fraenkel, Ernest;
    • Chiocca, E. Antonio
    Publication type:
    Article
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    High-resolution computational models of genome binding events.

    Published in:
    Nature Biotechnology, 2006, v. 24, n. 8, p. 963, doi. 10.1038/nbt1233
    By:
    • Yuan Qi;
    • Rolfe, Alex;
    • MacIsaac, Kenzie D.;
    • Gerber, Georg K.;
    • Pokholok, Dmitry;
    • Zeitlinger, Julia;
    • Danford, Timothy;
    • Dowell, Robin D.;
    • Fraenkel, Ernest;
    • Jaakkola, Tommi S.;
    • Young, Richard A.;
    • Gifford, David K.
    Publication type:
    Article
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    Computational discovery of gene modules and regulatory networks.

    Published in:
    Nature Biotechnology, 2003, v. 21, n. 11, p. 1337
    By:
    • Gerber, Georg K.;
    • Lee, Tong Ihn;
    • Rinaldi, Nicola J.;
    • Yoo, Jane Y.;
    • Robert, François;
    • Gordon, D. Benjamin;
    • Fraenkel, Ernest;
    • Jaakkola, Tommi S.;
    • Young, Richard A.;
    • Gifford, David K.
    Publication type:
    Article
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    Single cell metabolism: current and future trends.

    Published in:
    Metabolomics, 2022, v. 18, n. 10, p. 1, doi. 10.1007/s11306-022-01934-3
    By:
    • Ali, Ahmed;
    • Davidson, Shawn;
    • Fraenkel, Ernest;
    • Gilmore, Ian;
    • Hankemeier, Thomas;
    • Kirwan, Jennifer A.;
    • Lane, Andrew N.;
    • Lanekoff, Ingela;
    • Larion, Mioara;
    • McCall, Laura-Isobel;
    • Murphy, Michael;
    • Sweedler, Jonathan V.;
    • Zhu, Caigang
    Publication type:
    Article
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    An integrative systems-biology approach defines mechanisms of Alzheimer's disease neurodegeneration.

    Published in:
    Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59654-w
    By:
    • Leventhal, Matthew J.;
    • Zanella, Camila A.;
    • Kang, Byunguk;
    • Peng, Jiajie;
    • Gritsch, David;
    • Liao, Zhixiang;
    • Bukhari, Hassan;
    • Wang, Tao;
    • Pao, Ping-Chieh;
    • Danquah, Serwah;
    • Benetatos, Joseph;
    • Nehme, Ralda;
    • Farhi, Samouil;
    • Tsai, Li-Huei;
    • Dong, Xianjun;
    • Scherzer, Clemens R.;
    • Feany, Mel B.;
    • Fraenkel, Ernest
    Publication type:
    Article
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    Rare variant analyses validate known ALS genes in a multi-ethnic population and identifies ANTXR2 as a candidate in PLS.

    Published in:
    BMC Genomics, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12864-024-10538-1
    By:
    • Pottinger, Tess D.;
    • Motelow, Joshua E.;
    • Povysil, Gundula;
    • Moreno, Cristiane A. Martins;
    • Ren, Zhong;
    • Phatnani, Hemali;
    • Harms, Matthew B.;
    • Kwan, Justin;
    • Sareen, Dhruv;
    • Wang, Han-I.;
    • Broach, James R.;
    • Simmons, Zachary;
    • Arcila-Londono, Ximena;
    • Parrott, Steve;
    • Lee, Edward B.;
    • Deerlin, Vivianna M. Van;
    • Fraenkel, Ernest;
    • Ostrow, Lyle W.;
    • Baas, Frank;
    • Zaitlen, Noah
    Publication type:
    Article
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    Transcriptional regulatory code of a eukaryotic genome.

    Published in:
    Nature, 2004, v. 431, n. 7004, p. 99, doi. 10.1038/nature02800
    By:
    • Harbison, Christopher T.;
    • Gordon, D. Benjamin;
    • Lee, Tong Ihn;
    • Rinaldi, Nicola J.;
    • Macisaac, Kenzie D.;
    • Danford, Timothy W.;
    • Hannett, Nancy M.;
    • Tagne, Jean-Bosco;
    • Reynolds, David B.;
    • Yoo, Jane;
    • Jennings, Ezra G.;
    • Zeitlinger, Julia;
    • Pokholok, Dmirty K.;
    • Kellis, Manolis;
    • Rolfe, P. Alex;
    • Takusagawa, Ken T.;
    • Lander, Eric S.;
    • Gifford, David K.;
    • Fraenkel, Ernest;
    • Young, Richard A.
    Publication type:
    Article
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    The cycad genotoxin methylazoxymethanol, linked to Guam ALS/PDC, induces transcriptional mutagenesis.

    Published in:
    Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01725-y
    By:
    • Verheijen, Bert M.;
    • Chung, Claire;
    • Thompson, Ben;
    • Kim, Hyunjin;
    • Nakahara, Asa;
    • Anink, Jasper J.;
    • Mills, James D.;
    • NYGC ALS Consortium;
    • Phatnani, Hemali;
    • Kwan, Justin;
    • Sareen, Dhruv;
    • Broach, James R.;
    • Simmons, Zachary;
    • Arcila-Londono, Ximena;
    • Lee, Edward B.;
    • Van Deerlin, Vivianna M.;
    • Shneider, Neil A.;
    • Fraenkel, Ernest;
    • Ostrow, Lyle W.;
    • Baas, Frank
    Publication type:
    Article
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    Bmi1 Promotes Erythroid Development Through Regulating Ribosome Biogenesis.

    Published in:
    Stem Cells, 2015, v. 33, n. 3, p. 925, doi. 10.1002/stem.1896
    By:
    • Gao, Rui;
    • Kobayashi, Michihiro;
    • Yu, Hao;
    • Vemula, Sasidhar;
    • Yoder, Mervin C.;
    • Kapur, Reuben;
    • Liu, Yan;
    • Chen, Sisi;
    • Young, Sara K.;
    • Wek, Ronald C.;
    • Zhang, Yingchi;
    • Wan, Yang;
    • Zhu, Xiaofan;
    • Soltis, Anthony;
    • Fraenkel, Ernest;
    • Yu, Ming;
    • Cantor, Alan;
    • Antipin, Yevgeniy;
    • Xu, Yang;
    • Ellis, Steven R.
    Publication type:
    Article
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    Characteristics of myeloproliferative neoplasms in patients exposed to ionizing radiation following the Chernobyl nuclear accident.

    Published in:
    American Journal of Hematology, 2019, v. 94, n. 1, p. 62, doi. 10.1002/ajh.25307
    By:
    • Poluben, Larysa;
    • Puligandla, Maneka;
    • Neuberg, Donna;
    • Bryke, Christine R.;
    • Hsu, Yahsuan;
    • Shumeiko, Oleksandr;
    • Yuan, Xin;
    • Voznesensky, Olga;
    • Pihan, German;
    • Adam, Miriam;
    • Fraenkel, Ernest;
    • Rasnic, Roni;
    • Linial, Michal;
    • Klymenko, Sergiy;
    • Balk, Steven P.;
    • Fraenkel, Paula G.
    Publication type:
    Article
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    NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency.

    Published in:
    Scientific Data, 2023, v. 10, n. 1, p. 1, doi. 10.1038/s41597-022-01687-7
    By:
    • Matlock, Andrea D.;
    • Vaibhav, Vineet;
    • Holewinski, Ronald;
    • Venkatraman, Vidya;
    • Dardov, Victoria;
    • Manalo, Danica-Mae;
    • Shelley, Brandon;
    • Ornelas, Loren;
    • Banuelos, Maria;
    • Mandefro, Berhan;
    • Escalante-Chong, Renan;
    • Li, Jonathan;
    • Finkbeiner, Steve;
    • Fraenkel, Ernest;
    • Rothstein, Jeffrey;
    • Thompson, Leslie;
    • Sareen, Dhruv;
    • Svendsen, Clive N.;
    • NIH NeuroLINCS Consortium;
    • Van Eyk, Jennifer E.
    Publication type:
    Article
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