Works by Fraefel, Cornel

Results: 42

Cellular state landscape and herpes simplex virus type 1 infection progression are connected.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40148-6

By:

Pietilä, Maija K.;
Bachmann, Jana J.;
Ravantti, Janne;
Pelkmans, Lucas;
Fraefel, Cornel

Publication type:

Article

Inhibition of DNA Repair Mechanisms and Induction of Apoptosis in Triple Negative Breast Cancer Cells Expressing the Human Herpesvirus 6 U94.

Published in:

Cancers, 2019, v. 11, n. 7, p. 1006, doi. 10.3390/cancers11071006

By:

Caccuri, Francesca;
Sommariva, Michele;
Marsico, Stefania;
Giordano, Francesca;
Zani, Alberto;
Giacomini, Arianna;
Fraefel, Cornel;
Balsari, Andrea;
Caruso, Arnaldo

Publication type:

Article

Hazard potential of Swiss Ixodes ricinus ticks: Virome composition and presence of selected bacterial and protozoan pathogens.

Published in:

PLoS ONE, 2023, v. 18, n. 11, p. 1, doi. 10.1371/journal.pone.0290942

By:

Stegmüller, Stefanie;
Qi, Weihong;
Torgerson, Paul R.;
Fraefel, Cornel;
Kubacki, Jakub

Publication type:

Article

Adeno-associated virus type 2 (AAV2) uncoating is a stepwise process and is linked to structural reorganization of the nucleolus.

Published in:

PLoS Pathogens, 2022, v. 18, n. 7, p. 1, doi. 10.1371/journal.ppat.1010187

By:

Sutter, Sereina O.;
Lkharrazi, Anouk;
Schraner, Elisabeth M.;
Michaelsen, Kevin;
Meier, Anita Felicitas;
Marx, Jennifer;
Vogt, Bernd;
Büning, Hildegard;
Fraefel, Cornel

Publication type:

Article

HSV-1 infected cell proteins influence tetracycline-regulated transgene expression.

Published in:

Journal of Gene Medicine, 2000, v. 2, n. 5, p. 379, doi. 10.1002/1521-2254(200009/10)2:5<379::AID-JGM126>3.0.CO;2-G

By:

Herrlinger, Ulrich;
Pechan, Peter A.;
Jacobs, Andreas H.;
Woiciechowski, Christian;
Rainov, Nikolai G.;
Fraefel, Cornel;
Paulus, Werner;
Reeves, Steven A.

Publication type:

Article

MxB is an interferon-induced restriction factor of human herpesviruses.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04379-2

By:

Crameri, Michel;
Bauer, Michael;
Caduff, Nicole;
Walker, Raphael;
Steiner, Fiona;
Franzoso, Francesca D.;
Gujer, Cornelia;
Boucke, Karin;
Kucera, Talissa;
Zbinden, Andrea;
Münz, Christian;
Fraefel, Cornel;
Greber, Urs F.;
Pavlovic, Jovan

Publication type:

Article

Multitracer Positron Emission Tomographic Imaging of Exogenous Gene Expression Mediated by a Universal Herpes Simplex Virus 1 Amplicon Vector.

Published in:

Molecular Imaging, 2007, v. 6, n. 3, p. 181, doi. 10.2310/7290.2007.00015

By:

Kummer, Christiane;
Winkeler, Alexandra;
Dittmar, Claus;
Bauer, Bernd;
Rueger, Maria Adele;
Rueckriem, Benedikt;
Heneka, Michael T.;
Vollmar, Stefan;
Wienhard, Klaus;
Fraefel, Cornel;
Heiss, Wolf-Dieter;
Jacobs, Andreas H.

Publication type:

Article

Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus Replication.

Published in:

PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170908

By:

Seyffert, Michael;
Glauser, Daniel L.;
Schraner, Elisabeth M.;
de Oliveira, Anna-Paula;
Mansilla-Soto, Jorge;
Vogt, Bernd;
Büning, Hildegard;
Linden, R. Michael;
Ackermann, Mathias;
Fraefel, Cornel

Publication type:

Article

Herpes simplex virus co-infection facilitates rolling circle replication of the adeno-associated virus genome.

Published in:

PLoS Pathogens, 2021, v. 17, n. 6, p. 1, doi. 10.1371/journal.ppat.1009638

By:

Meier, Anita Felicitas;
Tobler, Kurt;
Leisi, Remo;
Lkharrazi, Anouk;
Ros, Carlos;
Fraefel, Cornel

Publication type:

Article

[18F]FLT PET for non-invasive monitoring of early response to gene therapy in experimental gliomas.

Published in:

2011

By:

Rueger, Maria A.;
Ameli, Mitra;
Hongfeng Li;
Winkeler, Alexandra;
Rueckriem, Benedikt;
Vollmar, Stefan;
Galldiks, Norbert;
Hesselmann, Volker;
Fraefel, Cornel;
Wienhard, Klaus;
Heiss, Wolf-Dieter;
Jacobs, Andreas H.;
Li, Hongfeng

Publication type:

journal article

Genetic Diversity of Hepatitis E Virus Type 3 in Switzerland—From Stable to Table.

Published in:

Animals (2076-2615), 2021, v. 11, n. 11, p. 3177, doi. 10.3390/ani11113177

By:

Vonlanthen-Specker, Isabelle;
Stephan, Roger;
Sidler, Xaver;
Moor, Dominik;
Fraefel, Cornel;
Bachofen, Claudia

Publication type:

Article

Paving the way for more precise diagnosis of EcPV2-associated equine penile lesions.

Published in:

BMC Veterinary Research, 2019, v. 15, n. 1, p. N.PAG, doi. 10.1186/s12917-019-2097-0

By:

Ramsauer, Anna Sophie;
Wachoski-Dark, Garrett Louis;
Fraefel, Cornel;
Tobler, Kurt;
Brandt, Sabine;
Knight, Cameron Greig;
Favrot, Claude;
Grest, Paula

Publication type:

Article

Recombinant Bovine Herpesvirus-1 (BHV-1) Lacking Transactivator Protein BICPO Entails Lack of Glycoprotein C and Severely Reduced Infectivity.

Published in:

Biological Chemistry, 1996, v. 377, n. 12, p. 787

By:

Köppel, Rene;
Fraefel, Cornel;
Vogt, Bernd;
Bello, Leonard J.;
Lawrence, William C.;
Schwyzer, Martin

Publication type:

Article

Porcine teschovirus, sapelovirus, and enterovirus in Swiss pigs: multiplex RT-PCR investigation of viral frequencies and disease association.

Published in:

Journal of Veterinary Diagnostic Investigation, 2021, v. 33, n. 5, p. 864, doi. 10.1177/10406387211025827

By:

Stäubli, Tamara;
Rickli, Charlotte I.;
Torgerson, Paul R.;
Fraefel, Cornel;
Lechmann, Julia

Publication type:

Article

Implementation of next-generation sequencing for virus identification in veterinary diagnostic laboratories.

Published in:

Journal of Veterinary Diagnostic Investigation, 2021, v. 33, n. 2, p. 235, doi. 10.1177/1040638720982630

By:

Kubacki, Jakub;
Fraefel, Cornel;
Bachofen, Claudia

Publication type:

Article

A novel PCR protocol for detection and differentiation of neuropathogenic and non-neuropathogenic equid alphaherpesvirus 1.

Published in:

Journal of Veterinary Diagnostic Investigation, 2019, v. 31, n. 5, p. 696, doi. 10.1177/1040638719871975

By:

Lechmann, Julia;
Schoster, Angelika;
Ernstberger, Martina;
Fouché, Nathalie;
Fraefel, Cornel;
Bachofen, Claudia

Publication type:

Article

The HSV-1 Transcription Factor ICP4 Confers Liquid-Like Properties to Viral Replication Compartments.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4447, doi. 10.3390/ijms22094447

By:

Seyffert, Michael;
Georgi, Fanny;
Tobler, Kurt;
Bourqui, Laurent;
Anfossi, Michela;
Michaelsen, Kevin;
Vogt, Bernd;
Greber, Urs F.;
Fraefel, Cornel;
Diefenbach, Russell J.

Publication type:

Article

The Cyclin-Dependent Kinase 5 Inhibitor Peptide Inhibits Herpes Simplex Virus Type 1 Replication.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-37989-3

By:

Man, Adrian;
Slevin, Mark;
Petcu, Eugen;
Fraefel, Cornel

Publication type:

Article

Metagenomic analysis of fecal and tissue samples from 18 endemic bat species in Switzerland revealed a diverse virus composition including potentially zoonotic viruses.

Published in:

PLoS ONE, 2021, v. 16, n. 6, p. 1, doi. 10.1371/journal.pone.0252534

By:

Hardmeier, Isabelle;
Aeberhard, Nadja;
Qi, Weihong;
Schoenbaechler, Katja;
Kraettli, Hubert;
Hatt, Jean-Michel;
Fraefel, Cornel;
Kubacki, Jakub

Publication type:

Article

Definition of Herpes Simplex Virus Type 1 Helper Activities for Adeno-Associated Virus Early Replication Events.

Published in:

PLoS Pathogens, 2009, v. 5, n. 3, p. 1, doi. 10.1371/journal.ppat.1000340

By:

Alazard-Dany1,2,3,4,, Nathalie;
Nicolas, Armel;
Ploquin, Aurélie;
Strasser, Regina;
Greco, Anna;
Epstein, Alberto L.;
Fraefel, Cornel;
Salvetti, Anna

Publication type:

Article

Differential Viral Genome Diversity of Healthy and RSS-Affected Broiler Flocks.

Published in:

Microorganisms, 2022, v. 10, n. 6, p. 1092, doi. 10.3390/microorganisms10061092

By:

Kubacki, Jakub;
Qi, Weihong;
Fraefel, Cornel

Publication type:

Article

Virus Diversity, Abundance, and Evolution in Three Different Bat Colonies in Switzerland.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 9, p. 1911, doi. 10.3390/v14091911

By:

Wiederkehr, Myriam Anja;
Qi, Weihong;
Schoenbaechler, Katja;
Fraefel, Cornel;
Kubacki, Jakub

Publication type:

Article

Establishment of a Three-Dimensional In Vitro Model of Equine Papillomavirus Type 2 Infection.

Published in:

Viruses (1999-4915), 2021, v. 13, n. 7, p. 1404, doi. 10.3390/v13071404

By:

Ramsauer, Anna Sophie;
Wachoski-Dark, Garrett Louis;
Fraefel, Cornel;
Ackermann, Mathias;
Brandt, Sabine;
Grest, Paula;
Knight, Cameron Greig;
Favrot, Claude;
Tobler, Kurt

Publication type:

Article

Viral Metagenomic Analysis of Aedes albopictus Mosquitos from Southern Switzerland.

Published in:

Viruses (1999-4915), 2020, v. 12, n. 9, p. 929, doi. 10.3390/v12090929

By:

Kubacki, Jakub;
Flacio, Eleonora;
Qi, Weihong;
Guidi, Valeria;
Tonolla, Mauro;
Fraefel, Cornel

Publication type:

Article

The Interplay between Adeno-Associated Virus and Its Helper Viruses.

Published in:

Viruses (1999-4915), 2020, v. 12, n. 6, p. 662, doi. 10.3390/v12060662

By:

Meier, Anita F.;
Fraefel, Cornel;
Seyffert, Michael

Publication type:

Article

Adenovirus Specific Pre-Immunity Induced by Natural Route of Infection Does Not Impair Transduction by Adenoviral Vaccine Vectors in Mice.

Published in:

PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0145260

By:

de Andrade Pereira, Bruna;
E. Maduro Bouillet, Leoneide;
Dorigo, Natalia A.;
Fraefel, Cornel;
Bruna-Romero, Oscar

Publication type:

Article

Rotavirus Viroplasm Fusion and Perinuclear Localization Are Dynamic Processes Requiring Stabilized Microtubules.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0047947

By:

Eichwald, Catherine;
Arnoldi, Francesca;
Laimbacher, Andrea S.;
Schraner, Elisabeth M.;
Fraefel, Cornel;
Wild, Peter;
Burrone, Oscar R.;
Ackermann, Mathias

Publication type:

Article

Assessment of a cellular vaccination approach consisting of crawling dendritic cells (CDCs) transduced with HSV-1-†pac vectors.

Published in:

Immunologic Research, 2004, v. 30, n. 1, p. 105, doi. 10.1385/IR:30:1:105

By:

Nuñez, Rafael;
Fraefel, Cornel;
Suter, Mark;
Nuñez-Liman, Anne;
Liou, Hisou-Chi;
Ackerman, Mathias

Publication type:

Article

Imaging Herpes Simplex Virus Type 1 Amplicon Vector--Mediated Gene Expression in Human Glioma Spheroids.

Published in:

Molecular Imaging, 2011, v. 10, n. 3, p. 197, doi. 10.2310/7290.2010.00036

By:

Kaestle, Christine;
Winkeler, Alexandra;
Richter, Raphaela;
Sauer, Heinrich;
Hescheler, Jürgen;
Fraefel, Cornel;
Wartenberg, Maria;
Jacobs, Andreas H.

Publication type:

Article

Integration of active human β-galactosidase gene (100 kb) into genome using HSV/AAV amplicon vector.

Published in:

Gene Therapy, 2007, v. 14, n. 14, p. 1078, doi. 10.1038/sj.gt.3302960

By:

Oehmig, A.;
Cortés, M. L.;
Perry, K. F.;
Sena-Esteves, M.;
Fraefel, Cornel;
Breakefield, X. O.

Publication type:

Article

In Vitro Comparison of the Internal Ribosomal Entry Site Activity from Rodent Hepacivirus and Pegivirus and Construction of Pseudoparticles.

Published in:

Advances in Virology, 2021, p. 1, doi. 10.1155/2021/5569844

By:

Sims, Stuart;
Michaelsen, Kevin;
Burkhard, Sara;
Fraefel, Cornel

Publication type:

Article

In Vitro Comparison of the Internal Ribosomal Entry Site Activity from Rodent Hepacivirus and Pegivirus and Construction of Pseudoparticles.

Published in:

Advances in Virology, 2021, p. 1, doi. 10.1155/2021/5569844

By:

Sims, Stuart;
Michaelsen, Kevin;
Burkhard, Sara;
Fraefel, Cornel

Publication type:

Article

Downregulated MicroRNA-200a in Meningiomas Promotes Tumor Growth by Reducing E-Cadherin and Activating the Wnt/β-Catenin Signaling Pathway.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 21, p. 5923, doi. 10.1128/MCB.00332-09

By:

Saydam, Okay;
Yiping Shen;
Würdinger, Thomas;
Senol, Ozlem;
Boke, Elvan;
James, Marianne F.;
Tannous, Bakhos A.;
Stemmer-Rachamimov, Anat O.;
Ming Yi;
Stephens, Robert M.;
Fraefel, Cornel;
Gusella, James F.;
Krichevsky, Anna M.;
Breakefield, Xandra O.

Publication type:

Article

Optimizing Glioblastoma Temozolomide Chemotherapy Employing Lentiviral-based Anti-MGMT shRNA Technology.

Published in:

Molecular Therapy, 2013, v. 21, n. 3, p. 570, doi. 10.1038/mt.2012.278

By:

Viel, Thomas;
Monfared, Parisa;
Schelhaas, Sonja;
Fricke, Inga B;
Kuhlmann, Michael T;
Fraefel, Cornel;
Jacobs, Andreas H

Publication type:

Article

HSV-1 Amplicon Vectors Launch the Production of Heterologous Rotavirus-like Particles and Induce Rotavirus-specific Immune Responses in Mice.

Published in:

Molecular Therapy, 2012, v. 20, n. 9, p. 1810, doi. 10.1038/mt.2012.108

By:

Laimbacher, Andrea S;
Esteban, Laura E;
Castello, Alejandro A;
Abdusetir Cerfoglio, Juan C;
Argüelles, Marcelo H;
Glikmann, Graciela;
D'Antuono, Alejandra;
Mattion, Nora;
Berois, Mabel;
Arbiza, Juan;
Hilbe, Monika;
Schraner, Elisabeth M;
Seyffert, Michael;
Dresch, Christiane;
Epstein, Alberto L;
Ackermann, Mathias;
Fraefel, Cornel

Publication type:

Article

Targeted Integration of Functional Human ATM cDNA Into Genome Mediated by HSV/AAV Hybrid Amplicon Vector.

Published in:

Molecular Therapy, 2008, v. 16, n. 1, p. 81, doi. 10.1038/sj.mt.6300338

By:

Cortés, Maria L.;
Oehmig, Angelika;
Saydam, Okay;
Sanford, Jocelyn D.;
Perry, Katherine F.;
Fraefel, Cornel;
Breakefield, Xandra O.

Publication type:

Article

Herpes Simplex Virus 1 Amplicon Vector-Mediated siRNA Targeting Epidermal Growth Factor Receptor Inhibits Growth of Human Glioma Cells in Vivo

Published in:

Molecular Therapy, 2005, v. 12, n. 5, p. 803, doi. 10.1016/j.ymthe.2005.07.534

By:

Saydam, Okay;
Glauser, Daniel L.;
Heid, Irma;
Turkeri, Gulen;
Hilbe, Monika;
Jacobs, Andreas H.;
Ackermann, Mathias;
Fraefel, Cornel

Publication type:

Article

724. Herpes Simplex Virus 1 Amplicon Vector-Mediated siRNA Targeting Epidermal Growth Factor Receptor Inhibits Growth of Human Glioma Cells in Culture and In Vivo

Published in:

2005

By:

Saydam, Okay;
Glauser, Daniel;
Heid, Irma;
Turkeri, Gulen;
Jacobs, Andreas;
Ackermann, Mathias;
Fraefel, Cornel

Publication type:

Abstract

Update on herpesvirus amplicon vectors

Published in:

Molecular Therapy, 2004, v. 10, n. 4, p. 630, doi. 10.1016/j.ymthe.2004.06.641

By:

Oehmig, Angelika;
Fraefel, Cornel;
Breakefield, Xandra O.

Publication type:

Article

One giant genomic leap for gene transfer technology

Published in:

Molecular Therapy, 2003, v. 7, n. 5, p. 571, doi. 10.1016/S1525-0016(03)00108-4

By:

Ackermann, Mathias;
Fraefel, Cornel

Publication type:

Article

Thymic but not splenic CD8<sup>+</sup> DCs can efficiently cross-prime T cells in the absence of licensing factors.

Published in:

European Journal of Immunology, 2011, v. 41, n. 9, p. 2544, doi. 10.1002/eji.201041374

By:

Dresch, Christiane;
Ackermann, Mathias;
Vogt, Bernd;
de Andrade Pereira, Bruna;
Shortman, Ken;
Fraefel, Cornel

Publication type:

Article

Antibody reactions of horses against various domains of the EHV-1 receptor-binding protein gD1.

Published in:

PLoS ONE, 2024, v. 19, n. 7, p. 1, doi. 10.1371/journal.pone.0301987

By:

Schramm, Andreina;
Ackermann, Mathias;
Eichwald, Catherine;
Aguilar, Claudio;
Fraefel, Cornel;
Lechmann, Julia

Publication type:

Article