Works by Fox, Todd E.

Results: 22

Altered Sphingolipid Metabolism in Patients with Metastatic Pancreatic Cancer.
Published in:
Biomolecules (2218-273X), 2013, v. 3, n. 3, p. 435, doi. 10.3390/biom3030435
By:
- Yixing Jiang;
- DiVittore, Nicole A.;
- Megan M. Young;
- Zhiliang Jia;
- Keping Xie;
- Ritty, Timothy M.;
- Kester, Mark;
- Fox, Todd E.
Publication type:
Article
Targeting sphingosine kinase-1 to inhibit melanoma.
Published in:
Pigment Cell & Melanoma Research, 2012, v. 25, n. 2, p. 259, doi. 10.1111/j.1755-148X.2012.00970.x
By:
- Madhunapantula, SubbaRao V.;
- Hengst, Jeremy;
- Gowda, Raghavendra;
- Fox, Todd E.;
- Yun, Jong K.;
- Robertson, Gavin P.
Publication type:
Article
Glucosylceramide synthase maintains influenza virus entry and infection.
Published in:
PLoS ONE, 2020, v. 15, n. 2, p. 1, doi. 10.1371/journal.pone.0228735
By:
- Drews, Kelly;
- Calgi, Michael P.;
- Harrison, William Casey;
- Drews, Camille M.;
- Costa-Pinheiro, Pedro;
- Shaw, Jeremy Joseph Porter;
- Jobe, Kendra A.;
- Han, John D.;
- Fox, Todd E.;
- White, Judith M.;
- Kester, Mark
Publication type:
Article
Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer.
Published in:
Cancer Biology & Therapy, 2011, v. 12, n. 7, p. 574, doi. 10.4161/cbt.12.7.15971
By:
- Yixing Jiang;
- Divittore, Nicole A.;
- Kaiser, James M.;
- Shanmugavelandy, Sriram S.;
- Fritz, Jennifer L.;
- Heakal, Yasser;
- Tagaram, Hephzibah Rani S.;
- Hua Cheng;
- Cabot, Myles C.;
- Staveley-O'Carroll, Kevin F.;
- Tran, Melissa A.;
- Fox, Todd E.;
- Barth, Brian M.;
- Kester, Mark
Publication type:
Article
Dysregulation of sphingolipid metabolism in cancer.
Published in:
Cancer Biology & Therapy, 2011, v. 11, n. 2, p. 138, doi. 10.4161/cbt.11.2.14624
By:
- Ryland, Lindsay K.;
- Fox, Todd E.;
- Liu, Xin;
- Loughran, Thomas P.;
- Kester, Mark
Publication type:
Article
Inhibition of NADPH oxidase by glucosylceramide confers chemoresistance.
Published in:
Cancer Biology & Therapy, 2010, v. 10, n. 11, p. 1126, doi. 10.4161/cbt.10.11.13438
By:
- Barth, Brian M.;
- Gustafson, Sally J.;
- Young, Megan M.;
- Fox, Todd E.;
- Shanmugavelandy, Sriram S.;
- Kaiser, James M.;
- Cabot, Myles C.;
- Kester, Mark;
- Kuhn, Thomas B.
Publication type:
Article
Large granular lymphocyte leukemia serum and corresponding hematological parameters reveal unique cytokine and sphingolipid biomarkers and associations with STAT3 mutations.
Published in:
Cancer Medicine, 2020, v. 9, n. 18, p. 6533, doi. 10.1002/cam4.3246
By:
- Olson, Kristine C.;
- Moosic, Katharine B.;
- Jones, Marieke K.;
- Larkin, Paige M. K.;
- Olson, Thomas L.;
- Toro, Mariella F.;
- Fox, Todd E.;
- Feith, David J.;
- Loughran, Thomas P.
Publication type:
Article
Pronecroptotic Therapy Using Ceramide Nanoliposomes Is Effective for Triple-Negative Breast Cancer Cells.
Published in:
Cells (2073-4409), 2024, v. 13, n. 5, p. 405, doi. 10.3390/cells13050405
By:
- Ohya, Yuki;
- Ogiso, Yuri;
- Matsuda, Masaya;
- Sakae, Harumi;
- Nishida, Kentaro;
- Miki, Yasuhiro;
- Fox, Todd E.;
- Kester, Mark;
- Sakamoto, Wataru;
- Nabe, Takeshi;
- Kitatani, Kazuyuki
Publication type:
Article
Ceramide Nanoliposomes as Potential Therapeutic Reagents for Asthma.
Published in:
Cells (2073-4409), 2023, v. 12, n. 4, p. 591, doi. 10.3390/cells12040591
By:
- Sakae, Harumi;
- Ogiso, Yuri;
- Matsuda, Masaya;
- Shimora, Hayato;
- Deering, Tye;
- Fox, Todd E.;
- Kester, Mark;
- Nabe, Takeshi;
- Kitatani, Kazuyuki
Publication type:
Article
Diabetes alters sphingolipid metabolism in the retina: a potential mechanism of cell death in diabetic retinopathy.
Published in:
2006
By:
- Fox TE;
- Han X;
- Kelly S;
- Merrill AH Jr.;
- Martin RE;
- Anderson RE;
- Gardner TW;
- Kester M;
- Fox, Todd E;
- Han, Xianlin;
- Kelly, Samuel;
- Merrill, Alfred H 2nd;
- Martin, Rex E;
- Anderson, Robert E;
- Gardner, Thomas W;
- Kester, Mark
Publication type:
journal article
Diabetes Alters Sphingolipid Metabolism in the Retina.
Published in:
Diabetes, 2006, v. 55, n. 12, p. 3573, doi. 10.2337/db06-0539
By:
- Fox, Todd E.;
- Xianlin Han;
- Kelly, Samuel;
- Merrill Jr., Alfred H.;
- Martin, Rex E.;
- Anderson, Robert E.;
- Gardner, Thomas W.;
- Kester, Mark
Publication type:
Article
Preclinical development of a C6-ceramide NanoLiposome, a novel sphingolipid therapeutic.
Published in:
Biological Chemistry, 2015, v. 396, n. 6/7, p. 737, doi. 10.1515/hsz-2015-0129
By:
- Kester, Mark;
- Bassler, Jocelyn;
- Fox, Todd E.;
- Carter, Carly J.;
- Davidson, Jeff A.;
- Parette, Mylisa R.
Publication type:
Article
A phase I study of the ceramide nanoliposome in patients with advanced solid tumors.
Published in:
Cancer Chemotherapy & Pharmacology, 2024, v. 93, n. 1, p. 23, doi. 10.1007/s00280-023-04588-7
By:
- Ciner, Aaron;
- Gourdin, Theodore;
- Davidson, Jeff;
- Parette, Mylisa;
- Walker, Susan J.;
- Fox, Todd E.;
- Jiang, Yixing
Publication type:
Article
Ceramide nanoliposomes augment the efficacy of venetoclax and cytarabine in models of acute myeloid leukemia.
Published in:
FASEB Journal, 2022, v. 36, n. 10, p. 1, doi. 10.1096/fj.202200765R
By:
- Khokhlatchev, Andrei V.;
- Sharma, Arati;
- Deering, Tye G.;
- Shaw, Jeremy J. P.;
- Costa‐Pinheiro, Pedro;
- Golla, Upendarrao;
- Annageldiyev, Charyguly;
- Cabot, Myles C.;
- Conaway, Mark R.;
- Tan, Su‐Fern;
- Ung, Johnson;
- Feith, David J.;
- Loughran, Thomas P.;
- Claxton, David F.;
- Fox, Todd E.;
- Kester, Mark
Publication type:
Article
Alterations in sphingolipid composition and mitochondrial bioenergetics represent synergistic therapeutic vulnerabilities linked to multidrug resistance in leukemia.
Published in:
FASEB Journal, 2022, v. 36, n. 1, p. 1, doi. 10.1096/fj.202101194RRR
By:
- Fisher-Wellman, Kelsey H.;
- Hagen, James T.;
- Kassai, Miki;
- Li-Pin Kao;
- Nelson, Margaret A. M.;
- McLaughlin, Kelsey L.;
- Coalson, Hannah S.;
- Fox, Todd E.;
- Su-Fern Tan;
- Feith, David J.;
- Kester, Mark;
- Loughran Jr, Thomas P.;
- Claxton, David F.;
- Cabot, Myles C.
Publication type:
Article
Glucosylceramide production maintains colon integrity in response to Bacteroides fragilis toxin‐induced colon epithelial cell signaling.
Published in:
FASEB Journal, 2020, v. 34, n. 12, p. 15922, doi. 10.1096/fj.202001669R
By:
- Patterson, Logan;
- Allen, Jawara;
- Posey, Isabella;
- Shaw, Jeremy Joseph Porter;
- Costa‐Pinheiro, Pedro;
- Walker, Susan J.;
- Gademsey, Alexis;
- Wu, Xinqun;
- Wu, Shaoguang;
- Zachos, Nicholas C.;
- Fox, Todd E.;
- Sears, Cynthia L.;
- Kester, Mark
Publication type:
Article
Nervonic acid limits weight gain in a mouse model of diet‐induced obesity.
Published in:
FASEB Journal, 2020, v. 34, n. 11, p. 15314, doi. 10.1096/fj.202000525R
By:
- Keppley, Laura J. W.;
- Walker, Susan J.;
- Gademsey, Alexis N.;
- Smith, Jason P.;
- Keller, Susanna R.;
- Kester, Mark;
- Fox, Todd E.
Publication type:
Article
Targeting glucosylceramide synthase synergizes with C<sub>6</sub>-ceramide nanoliposomes to induce apoptosis in natural killer cell leukemia.
Published in:
Leukemia & Lymphoma, 2013, v. 54, n. 6, p. 1288, doi. 10.3109/10428194.2012.752485
By:
- Watters, Rebecca J.;
- Fox, Todd E.;
- Tan, Su-Fern;
- Shanmugavelandy, Sriram;
- Choby, Jacob E.;
- Broeg, Kathleen;
- Liao, Jason;
- Kester, Mark;
- Cabot, Myles C.;
- Loughran, Thomas P.;
- Liu, Xin
Publication type:
Article
Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia.
Published in:
Cancers, 2023, v. 15, n. 24, p. 5866, doi. 10.3390/cancers15245866
By:
- Ung, Johnson;
- Tan, Su-Fern;
- Fox, Todd E.;
- Shaw, Jeremy J. P.;
- Taori, Maansi;
- Horton, Bethany J.;
- Golla, Upendarrao;
- Sharma, Arati;
- Szulc, Zdzislaw M.;
- Wang, Hong-Gang;
- Chalfant, Charles E.;
- Cabot, Myles C.;
- Claxton, David F.;
- Loughran Jr., Thomas P.;
- Feith, David J.
Publication type:
Article
Simultaneous Inhibition of Ceramide Hydrolysis and Glycosylation Synergizes to Corrupt Mitochondrial Respiration and Signal Caspase Driven Cell Death in Drug-Resistant Acute Myeloid Leukemia.
Published in:
Cancers, 2023, v. 15, n. 6, p. 1883, doi. 10.3390/cancers15061883
By:
- Fisher-Wellman, Kelsey H.;
- Kassai, Miki;
- Hagen, James T.;
- Neufer, P. Darrell;
- Kester, Mark;
- Loughran Jr., Thomas P.;
- Chalfant, Charles E.;
- Feith, David J.;
- Tan, Su-Fern;
- Fox, Todd E.;
- Ung, Johnson;
- Fabrias, Gemma;
- Abad, Jose' Luis;
- Sharma, Arati;
- Golla, Upendarrao;
- Claxton, David F.;
- Shaw, Jeremy J. P.;
- Bhowmick, Debajit;
- Cabot, Myles C.
Publication type:
Article
C6-Ceramide Nanoliposomes Target the Warburg Effect in Chronic Lymphocytic Leukemia.
Published in:
PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0084648
By:
- Ryland, Lindsay K.;
- Doshi, Ushma A.;
- Shanmugavelandy, Sriram S.;
- Fox, Todd E.;
- Aliaga, Cesar;
- Broeg, Kathleen;
- Baab, Kendall Thomas;
- Young, Megan;
- Khan, Osman;
- Haakenson, Jeremy K.;
- Jarbadan, Nancy Ruth;
- Liao, Jason;
- Wang, Hong-Gang;
- Feith, David J.;
- Loughran Jr, Thomas P.;
- Liu, Xin;
- Kester, Mark
Publication type:
Article
Bif-1 regulates Atg9 trafficking by mediating the fission of Golgi membranes during autophagy.
Published in:
Autophagy, 2011, v. 7, n. 1, p. 61, doi. 10.4161/auto.7.1.14015
By:
- Takahashi, Yoshinori;
- Meyerkord, Cheryl L.;
- Hori, Tsukasa;
- Runkle, Kristin;
- Fox, Todd E.;
- Kester, Mark;
- Loughran, Thomas P.;
- Hong-Gang Wang
Publication type:
Article