Works matching AU Fox, Todd E.

Results: 22

Targeting sphingosine kinase-1 to inhibit melanoma.

Published in:

Pigment Cell & Melanoma Research, 2012, v. 25, n. 2, p. 259, doi. 10.1111/j.1755-148X.2012.00970.x

By:

Madhunapantula, SubbaRao V.;
Hengst, Jeremy;
Gowda, Raghavendra;
Fox, Todd E.;
Yun, Jong K.;
Robertson, Gavin P.

Publication type:

Article

Ceramide nanoliposomes augment the efficacy of venetoclax and cytarabine in models of acute myeloid leukemia.

Published in:

FASEB Journal, 2022, v. 36, n. 10, p. 1, doi. 10.1096/fj.202200765R

By:

Khokhlatchev, Andrei V.;
Sharma, Arati;
Deering, Tye G.;
Shaw, Jeremy J. P.;
Costa‐Pinheiro, Pedro;
Golla, Upendarrao;
Annageldiyev, Charyguly;
Cabot, Myles C.;
Conaway, Mark R.;
Tan, Su‐Fern;
Ung, Johnson;
Feith, David J.;
Loughran, Thomas P.;
Claxton, David F.;
Fox, Todd E.;
Kester, Mark

Publication type:

Article

Alterations in sphingolipid composition and mitochondrial bioenergetics represent synergistic therapeutic vulnerabilities linked to multidrug resistance in leukemia.

Published in:

FASEB Journal, 2022, v. 36, n. 1, p. 1, doi. 10.1096/fj.202101194RRR

By:

Fisher-Wellman, Kelsey H.;
Hagen, James T.;
Kassai, Miki;
Li-Pin Kao;
Nelson, Margaret A. M.;
McLaughlin, Kelsey L.;
Coalson, Hannah S.;
Fox, Todd E.;
Su-Fern Tan;
Feith, David J.;
Kester, Mark;
Loughran Jr, Thomas P.;
Claxton, David F.;
Cabot, Myles C.

Publication type:

Article

Glucosylceramide production maintains colon integrity in response to Bacteroides fragilis toxin‐induced colon epithelial cell signaling.

Published in:

FASEB Journal, 2020, v. 34, n. 12, p. 15922, doi. 10.1096/fj.202001669R

By:

Patterson, Logan;
Allen, Jawara;
Posey, Isabella;
Shaw, Jeremy Joseph Porter;
Costa‐Pinheiro, Pedro;
Walker, Susan J.;
Gademsey, Alexis;
Wu, Xinqun;
Wu, Shaoguang;
Zachos, Nicholas C.;
Fox, Todd E.;
Sears, Cynthia L.;
Kester, Mark

Publication type:

Article

Nervonic acid limits weight gain in a mouse model of diet‐induced obesity.

Published in:

FASEB Journal, 2020, v. 34, n. 11, p. 15314, doi. 10.1096/fj.202000525R

By:

Keppley, Laura J. W.;
Walker, Susan J.;
Gademsey, Alexis N.;
Smith, Jason P.;
Keller, Susanna R.;
Kester, Mark;
Fox, Todd E.

Publication type:

Article

A phase I study of the ceramide nanoliposome in patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2024, v. 93, n. 1, p. 23, doi. 10.1007/s00280-023-04588-7

By:

Ciner, Aaron;
Gourdin, Theodore;
Davidson, Jeff;
Parette, Mylisa;
Walker, Susan J.;
Fox, Todd E.;
Jiang, Yixing

Publication type:

Article

Large granular lymphocyte leukemia serum and corresponding hematological parameters reveal unique cytokine and sphingolipid biomarkers and associations with STAT3 mutations.

Published in:

Cancer Medicine, 2020, v. 9, n. 18, p. 6533, doi. 10.1002/cam4.3246

By:

Olson, Kristine C.;
Moosic, Katharine B.;
Jones, Marieke K.;
Larkin, Paige M. K.;
Olson, Thomas L.;
Toro, Mariella F.;
Fox, Todd E.;
Feith, David J.;
Loughran, Thomas P.

Publication type:

Article

Pronecroptotic Therapy Using Ceramide Nanoliposomes Is Effective for Triple-Negative Breast Cancer Cells.

Published in:

Cells (2073-4409), 2024, v. 13, n. 5, p. 405, doi. 10.3390/cells13050405

By:

Ohya, Yuki;
Ogiso, Yuri;
Matsuda, Masaya;
Sakae, Harumi;
Nishida, Kentaro;
Miki, Yasuhiro;
Fox, Todd E.;
Kester, Mark;
Sakamoto, Wataru;
Nabe, Takeshi;
Kitatani, Kazuyuki

Publication type:

Article

Ceramide Nanoliposomes as Potential Therapeutic Reagents for Asthma.

Published in:

Cells (2073-4409), 2023, v. 12, n. 4, p. 591, doi. 10.3390/cells12040591

By:

Sakae, Harumi;
Ogiso, Yuri;
Matsuda, Masaya;
Shimora, Hayato;
Deering, Tye;
Fox, Todd E.;
Kester, Mark;
Nabe, Takeshi;
Kitatani, Kazuyuki

Publication type:

Article

Glucosylceramide synthase maintains influenza virus entry and infection.

Published in:

PLoS ONE, 2020, v. 15, n. 2, p. 1, doi. 10.1371/journal.pone.0228735

By:

Drews, Kelly;
Calgi, Michael P.;
Harrison, William Casey;
Drews, Camille M.;
Costa-Pinheiro, Pedro;
Shaw, Jeremy Joseph Porter;
Jobe, Kendra A.;
Han, John D.;
Fox, Todd E.;
White, Judith M.;
Kester, Mark

Publication type:

Article

Preclinical development of a C6-ceramide NanoLiposome, a novel sphingolipid therapeutic.

Published in:

Biological Chemistry, 2015, v. 396, n. 6/7, p. 737, doi. 10.1515/hsz-2015-0129

By:

Kester, Mark;
Bassler, Jocelyn;
Fox, Todd E.;
Carter, Carly J.;
Davidson, Jeff A.;
Parette, Mylisa R.

Publication type:

Article

Targeting glucosylceramide synthase synergizes with C<sub>6</sub>-ceramide nanoliposomes to induce apoptosis in natural killer cell leukemia.

Published in:

Leukemia & Lymphoma, 2013, v. 54, n. 6, p. 1288, doi. 10.3109/10428194.2012.752485

By:

Watters, Rebecca J.;
Fox, Todd E.;
Tan, Su-Fern;
Shanmugavelandy, Sriram;
Choby, Jacob E.;
Broeg, Kathleen;
Liao, Jason;
Kester, Mark;
Cabot, Myles C.;
Loughran, Thomas P.;
Liu, Xin

Publication type:

Article

Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer.

Published in:

Cancer Biology & Therapy, 2011, v. 12, n. 7, p. 574, doi. 10.4161/cbt.12.7.15971

By:

Yixing Jiang;
Divittore, Nicole A.;
Kaiser, James M.;
Shanmugavelandy, Sriram S.;
Fritz, Jennifer L.;
Heakal, Yasser;
Tagaram, Hephzibah Rani S.;
Hua Cheng;
Cabot, Myles C.;
Staveley-O'Carroll, Kevin F.;
Tran, Melissa A.;
Fox, Todd E.;
Barth, Brian M.;
Kester, Mark

Publication type:

Article

Dysregulation of sphingolipid metabolism in cancer.

Published in:

Cancer Biology & Therapy, 2011, v. 11, n. 2, p. 138, doi. 10.4161/cbt.11.2.14624

By:

Ryland, Lindsay K.;
Fox, Todd E.;
Liu, Xin;
Loughran, Thomas P.;
Kester, Mark

Publication type:

Article

Inhibition of NADPH oxidase by glucosylceramide confers chemoresistance.

Published in:

Cancer Biology & Therapy, 2010, v. 10, n. 11, p. 1126, doi. 10.4161/cbt.10.11.13438

By:

Barth, Brian M.;
Gustafson, Sally J.;
Young, Megan M.;
Fox, Todd E.;
Shanmugavelandy, Sriram S.;
Kaiser, James M.;
Cabot, Myles C.;
Kester, Mark;
Kuhn, Thomas B.

Publication type:

Article

Altered Sphingolipid Metabolism in Patients with Metastatic Pancreatic Cancer.

Published in:

Biomolecules (2218-273X), 2013, v. 3, n. 3, p. 435, doi. 10.3390/biom3030435

By:

Yixing Jiang;
DiVittore, Nicole A.;
Megan M. Young;
Zhiliang Jia;
Keping Xie;
Ritty, Timothy M.;
Kester, Mark;
Fox, Todd E.

Publication type:

Article

Bif-1 regulates Atg9 trafficking by mediating the fission of Golgi membranes during autophagy.

Published in:

Autophagy, 2011, v. 7, n. 1, p. 61, doi. 10.4161/auto.7.1.14015

By:

Takahashi, Yoshinori;
Meyerkord, Cheryl L.;
Hori, Tsukasa;
Runkle, Kristin;
Fox, Todd E.;
Kester, Mark;
Loughran, Thomas P.;
Hong-Gang Wang

Publication type:

Article

Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia.

Published in:

Cancers, 2023, v. 15, n. 24, p. 5866, doi. 10.3390/cancers15245866

By:

Ung, Johnson;
Tan, Su-Fern;
Fox, Todd E.;
Shaw, Jeremy J. P.;
Taori, Maansi;
Horton, Bethany J.;
Golla, Upendarrao;
Sharma, Arati;
Szulc, Zdzislaw M.;
Wang, Hong-Gang;
Chalfant, Charles E.;
Cabot, Myles C.;
Claxton, David F.;
Loughran Jr., Thomas P.;
Feith, David J.

Publication type:

Article

Simultaneous Inhibition of Ceramide Hydrolysis and Glycosylation Synergizes to Corrupt Mitochondrial Respiration and Signal Caspase Driven Cell Death in Drug-Resistant Acute Myeloid Leukemia.

Published in:

Cancers, 2023, v. 15, n. 6, p. 1883, doi. 10.3390/cancers15061883

By:

Fisher-Wellman, Kelsey H.;
Kassai, Miki;
Hagen, James T.;
Neufer, P. Darrell;
Kester, Mark;
Loughran Jr., Thomas P.;
Chalfant, Charles E.;
Feith, David J.;
Tan, Su-Fern;
Fox, Todd E.;
Ung, Johnson;
Fabrias, Gemma;
Abad, Jose' Luis;
Sharma, Arati;
Golla, Upendarrao;
Claxton, David F.;
Shaw, Jeremy J. P.;
Bhowmick, Debajit;
Cabot, Myles C.

Publication type:

Article

Diabetes alters sphingolipid metabolism in the retina: a potential mechanism of cell death in diabetic retinopathy.

Published in:

2006

By:

Fox TE;
Han X;
Kelly S;
Merrill AH Jr.;
Martin RE;
Anderson RE;
Gardner TW;
Kester M;
Fox, Todd E;
Han, Xianlin;
Kelly, Samuel;
Merrill, Alfred H 2nd;
Martin, Rex E;
Anderson, Robert E;
Gardner, Thomas W;
Kester, Mark

Publication type:

journal article

Diabetes Alters Sphingolipid Metabolism in the Retina.

Published in:

Diabetes, 2006, v. 55, n. 12, p. 3573, doi. 10.2337/db06-0539

By:

Fox, Todd E.;
Xianlin Han;
Kelly, Samuel;
Merrill Jr., Alfred H.;
Martin, Rex E.;
Anderson, Robert E.;
Gardner, Thomas W.;
Kester, Mark

Publication type:

Article

C6-Ceramide Nanoliposomes Target the Warburg Effect in Chronic Lymphocytic Leukemia.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0084648

By:

Ryland, Lindsay K.;
Doshi, Ushma A.;
Shanmugavelandy, Sriram S.;
Fox, Todd E.;
Aliaga, Cesar;
Broeg, Kathleen;
Baab, Kendall Thomas;
Young, Megan;
Khan, Osman;
Haakenson, Jeremy K.;
Jarbadan, Nancy Ruth;
Liao, Jason;
Wang, Hong-Gang;
Feith, David J.;
Loughran Jr, Thomas P.;
Liu, Xin;
Kester, Mark

Publication type:

Article