Works by Forst, Thomas

Results: 70

Novel pharmacotherapies for weight loss: Understanding the role of incretins to enable weight loss and improved health outcomes.

Published in:

Diabetes, Obesity & Metabolism, 2025, v. 27, p. 48, doi. 10.1111/dom.16247

By:

Forst, Thomas;
De Block, Christophe;
Del Prato, Stefano;
Frias, Juan;
Lautenbach, Anne;
Ludvik, Bernhard;
Marinez, Marina;
Mathieu, Chantal;
Müller, Timo D.;
Schnell, Oliver

Publication type:

Article

A randomized phase I study of BI 1820237, a novel neuropeptide Y receptor type 2 agonist, alone or in combination with low‐dose liraglutide in otherwise healthy men with overweight or obesity.

Published in:

Diabetes, Obesity & Metabolism, 2025, v. 27, n. 1, p. 71, doi. 10.1111/dom.15984

By:

Beetz, Nadine;
Kalsch, Brigitte;
Forst, Thomas;
Schmid, Bernhard;
Schultz, Armin;
Hennige, Anita M.

Publication type:

Article

The role of incretin receptor agonists in the treatment of obesity.

Published in:

Diabetes, Obesity & Metabolism, 2024, v. 26, n. 10, p. 4178, doi. 10.1111/dom.15796

By:

Forst, Thomas;
De Block, Christophe;
Del Prato, Stefano;
Armani, Sara;
Frias, Juan;
Lautenbach, Anne;
Ludvik, Bernhard;
Marinez, Marina;
Mathieu, Chantal;
Müller, Timo D.;
Schnell, Oliver

Publication type:

Article

Effects on α- and β-cell function of sequentially adding empagliflozin and linagliptin to therapy in people with type 2 diabetes previously receiving metformin: An exploratory mechanistic study.

Published in:

Diabetes, Obesity & Metabolism, 2017, v. 19, n. 4, p. 489, doi. 10.1111/dom.12838

By:

Forst, Thomas;
Falk, Alexander;
Andersen, Grit;
Fischer, Annelie;
Weber, Matthias M.;
Voswinkel, Stephan;
Heise, Tim;
Kapitza, Christoph;
Plum‐Mörschel, Leona

Publication type:

Article

Euglycaemic glucose clamp: what it can and cannot do, and how to do it.

Published in:

Diabetes, Obesity & Metabolism, 2016, v. 18, n. 10, p. 962, doi. 10.1111/dom.12703

By:

Heise, Tim;
Zijlstra, Eric;
Nosek, Leszek;
Heckermann, Sascha;
Plum‐Mörschel, Leona;
Forst, Thomas

Publication type:

Article

Influence of Glucose Control and Improvement of Insulin Resistance on Microvascular Blood Flow and Endothelial Function in Patients with Diabetes Mellitus Type 2.

Published in:

Microcirculation, 2005, v. 12, n. 7, p. 543, doi. 10.1080/10739680500253402

By:

Forst, Thomas;
Lübben, Georg;
Hohberg, Clothilde;
Kann, Peter;
Sachara, Christian;
Gottschall, Volker;
Friedrich, Christiane;
Roýkopf, Reiner;
Pfützner, Andreas

Publication type:

Article

Report from the CVOT Summit 2021: new cardiovascular, renal, and glycemic outcomes.

Published in:

Cardiovascular Diabetology, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12933-022-01481-0

By:

Schnell, Oliver;
Battelino, Tadej;
Bergenstal, Richard;
Blüher, Matthias;
Böhm, Michael;
Brosius, Frank;
Carr, Richard D.;
Ceriello, Antonio;
Forst, Thomas;
Giorgino, Francesco;
Guerci, Bruno;
Heerspink, Hiddo J. L.;
Itzhak, Baruch;
Ji, Linong;
Kosiborod, Mikhail;
Lalić, Nebojša;
Lehrke, Michael;
Marx, Nikolaus;
Nauck, Michael;
Rodbard, Helena W.

Publication type:

Article

Report from the CVOT Summit 2020: new cardiovascular and renal outcomes.

Published in:

2021

By:

Schnell, Oliver;
Cos, Xavier;
Cosentino, Francesco;
Forst, Thomas;
Giorgino, Francesco;
Heersprink, Hiddo J. L.;
Kosiborod, Mikhail;
Wanner, Christoph;
Standl, Eberhard

Publication type:

Editorial

Report from the CVOT Summit 2020: new cardiovascular and renal outcomes.

Published in:

2021

By:

Schnell, Oliver;
Cos, Xavier;
Cosentino, Francesco;
Forst, Thomas;
Giorgino, Francesco;
Heersprink, Hiddo J. L.;
Kosiborod, Mikhail;
Wanner, Christoph;
Standl, Eberhard

Publication type:

Editorial

Report from the CVOT Summit 2020: new cardiovascular and renal outcomes.

Published in:

2021

By:

Schnell, Oliver;
Cos, Xavier;
Cosentino, Francesco;
Forst, Thomas;
Giorgino, Francesco;
Heersprink, Hiddo J. L.;
Kosiborod, Mikhail;
Wanner, Christoph;
Standl, Eberhard

Publication type:

Editorial

Problems with the determination of nitrotyrosine in human plasma are not solved in a satisfactory way and conclusions from clinical trials need to be carefully revised.

Published in:

Clinical Chemistry & Laboratory Medicine, 2010, v. 48, n. 1, p. 145, doi. 10.1515/CCLM.2010.025

By:

Pfützner, Andreas;
Safinowski, Michael;
Forst, Thomas

Publication type:

Article

Determination of nitrotyrosine concentrations in plasma samples of diabetes mellitus patients by four different immunoassays leads to contradictive results and disqualifies the majority of the tests.

Published in:

Clinical Chemistry & Laboratory Medicine, 2009, v. 47, n. 4, p. 483, doi. 10.1515/CCLM.2009.095

By:

Safinowski, Michael;
Wilhelm, Birgit;
Reimer, Tanja;
Weise, Alexander;
Thomé, Nicole;
Hänel, Heike;
Forst, Thomas;
Pfützner, Andreas

Publication type:

Article

Association of high-sensitive C-reactive protein with advanced stage β-cell dysfunction and insulin resistance in patients with type 2 diabetes mellitus.

Published in:

Clinical Chemistry & Laboratory Medicine, 2006, v. 44, n. 5, p. 556, doi. 10.1515/CCLM.2006.108

By:

Pfützner, Andreas;
Standl, Eberhard;
Strotmann, Hermann-Josef;
Schulze, Jan;
Hohberg, Cloth;
Lübben, Georg;
Pahler, Sabine;
Schöndorf, Thomas;
Forst, Thomas

Publication type:

Article

Clinical and Laboratory Evaluation of Specific Chemiluminescence Assays for Intact and Total Proinsulin.

Published in:

Clinical Chemistry & Laboratory Medicine, 2003, v. 41, n. 9, p. 1234

By:

Pfutzner, Andreas;
Kunt, Thomas;
Langenfeld, Matthias;
Lobig, Mirjam;
Knesovic, Maja;
Forst, Thomas

Publication type:

Article

Cardiovascular Benefits of GLP-1-Based Therapies in Patients with Diabetes Mellitus Type 2: Effects on Endothelial and Vascular Dysfunction beyond Glycemic Control.

Published in:

Experimental Diabetes Research, 2012, p. 1, doi. 10.1155/2012/635472

By:

Forst, Thomas;
Weber, Matthias M.;
Pfützner, Andreas

Publication type:

Article

C-Peptide and Its C-Terminal Fragments Improve Erythrocyte Deformability in Type 1 Diabetes Patients.

Published in:

Experimental Diabetes Research, 2009, p. 1, doi. 10.1155/2008/730594

By:

Hach, Thomas;
Forst, Thomas;
Kunt, Thomas;
Ekberg, Karin;
Pfützner, Andreas;
Wahren, John

Publication type:

Article

New Tricks by an Old Dog.

Published in:

Experimental Diabetes Research, 2009, p. 1, doi. 10.1155/2008/384219

By:

Forst, Thomas;
Wahren, John

Publication type:

Article

C-Peptide and Its C-Terminal Fragments Improve Erythrocyte Deformability in Type 1 Diabetes Patients.

Published in:

Experimental Diabetes Research, 2008, p. 1, doi. 10.1155/2008/730594

By:

Hach, Thomas;
Forst, Thomas;
Kunt, Thomas;
Ekberg, Karin;
Pfützner, Andreas;
Wahren, John

Publication type:

Article

Accuracy and Longevity of an Implantable Continuous Glucose Sensor in the PRECISE Study: A 180-Day, Prospective, Multicenter, Pivotal Trial.

Published in:

2017

By:

Kropff, Jort;
Choudhary, Pratik;
Neupane, Sankalpa;
Barnard, Katharine;
Bain, Steve C.;
Kapitza, Christoph;
Forst, Thomas;
Link, Manuela;
Dehennis, Andrew;
DeVries, J. Hans

Publication type:

journal article

Contrasting Effects of Lixisenatide and Liraglutide on Postprandial Glycemic Control, Gastric Emptying, and Safety Parameters in Patients With Type 2 Diabetes on Optimized Insulin Glargine With or Without Metformin: A Randomized, Open-Label Trial.

Published in:

Diabetes Care, 2015, v. 38, n. 7, p. 1263, doi. 10.2337/dc14-1984

By:

Meier, Juris J.;
Rosenstock, Julio;
Hincelin-Méry, Agnès;
Roy-Duval, Christine;
Delfolie, Astrid;
Coester, Hans-Veit;
Menge, Bjoern A.;
Forst, Thomas;
Kapitza, Christoph

Publication type:

Article

Rosiglitazone and glimeperide: review of clinical results supporting a fixed dose combination.

Published in:

2007

By:

Pfützner, Andreas;
Wilhelm, Birgit;
Forst, Thomas

Publication type:

journal article

Lixisenatide as add-on to insulin glargine for the treatment of type 2 diabetes mellitus.

Published in:

Expert Opinion on Pharmacotherapy, 2016, v. 17, n. 12, p. 1703, doi. 10.1080/14656566.2016.1206079

By:

Forst, Thomas

Publication type:

Article

Pharmacological profile, efficacy and safety of in type 2 diabetes mellitus.

Published in:

Expert Opinion on Pharmacotherapy, 2013, v. 14, n. 16, p. 2281, doi. 10.1517/14656566.2013.838559

By:

Forst, Thomas;
Pfützner, Andreas

Publication type:

Article

Downregulation of the Proinflammatory State of Circulating of Mononuclear Cells by Short-Term Treatment with Pioglitazone in Patients with Type 2 Diabetes Mellitus and Coronary Artery Disease.

Published in:

PPAR Research, 2011, p. 1, doi. 10.1155/2011/647017

By:

Pfützner, Andreas;
Weise, Alexander;
Pfützner-Riehn, Elisabeth;
Lübben, Georg;
Morcos, Michael;
Karagiannis, Efstrathios;
Weber, Matthias;
Forst, Thomas

Publication type:

Article

Adding once-daily lixisenatide for type 2 diabetes inadequately controlled with newly initiated and continuously titrated basal insulin glargine: a 24-week, randomized, placebo-controlled study (GetGoal-Duo 1).

Published in:

2013

By:

Riddle, Matthew C;
Forst, Thomas;
Aronson, Ronnie;
Sauque-Reyna, Leobardo;
Souhami, Elisabeth;
Silvestre, Louise;
Ping, Lin;
Rosenstock, Julio

Publication type:

journal article

Adding Once-Daily Lixisenatide for Type 2 Diabetes Inadequately Controlled With Newly Initiated and Continuously Titrated Basal Insulin Glargine.

Published in:

Diabetes Care, 2013, v. 36, n. 9, p. 2497, doi. 10.2337/dc12-2462

By:

RIDDLE, MATTHEW C.;
FORST, THOMAS;
ARONSON, RONNIE;
SAUQUE-REYNA, LEOBARDO;
SOUHAMI, ELISABETH;
SILVESTRE, LOUISE;
LIN PING;
ROSENSTOCK, JULIO

Publication type:

Article

Postprandial Vascular Effects of VIAject Compared With Insulin Lispro and Regular Human Insulin in Patients With Type 2 Diabetes.

Published in:

Diabetes Care, 2010, v. 33, n. 1, p. 116, doi. 10.2337/dc09-0411

By:

Forst, Thomas;
PfÜtzner, Andreas;
Flacke, Frank;
Krasner, Alan;
Hohberg, Cloth;
Tarakci, Eda;
Pichotta, Philip;
Forst, Senait;
Steiner, Solomon

Publication type:

Article

Effect of Insulin Glulisine on Microvascular Blood Flow and Endothelial Function in the Postprandial State.

Published in:

Diabetes Care, 2008, v. 31, n. 5, p. 1021, doi. 10.2337/dc07-2185

By:

Hohberg, Clothilde;
Forst, Thomas;
Larbig, Martin;
Safinowski, Michael;
Diessel, Stefan;
Hehenwarter, Silvia;
Weber, Matthias M.;
Schöndorf, Thomas;
Pfützner, Andreas

Publication type:

Article

Development and Validation of a New Measure to Evaluate Psychological Resistance to Insulin Treatment.

Published in:

Diabetes Care, 2007, v. 30, n. 9, p. 2199, doi. 10.2337/dc06-2042

By:

Petrak, Frank;
Stridde, Elmar;
Leverkus, Friedhelm;
Crispin, Alexander A.;
Forst, Thomas;
Pfützner, Andreas

Publication type:

Article

Fasting intact proinsulin is a highly specific predictor of insulin resistance in type 2 diabetes.

Published in:

2004

By:

Pfützner, Andreas;
Kunt, Thomas;
Hohberg, Cloth;
Mondok, Agnes;
Pahler, Sabine;
Konrad, Thomas;
Lübben, Georg;
Forst, Thomas;
Pfützner, Andreas;
Lübben, Georg

Publication type:

journal article

Effect of C-peptide on glucose metabolism in patients with type 1 diabetes.

Published in:

2002

By:

Forst, Thomas;
Pfuetzner, Andreas;
Pohlmann, Thomas;
Lobig, Mirjam;
Rave, Klaus;
Buchholz, Ronald;
Heinemann, Lutz;
Löbig, Mirjam

Publication type:

clinical trial

Response to Jungheim and Koschinsky.

Published in:

2002

By:

PFÜTZNER, ANDREAS;
FORST, THOMAS;
JUNGHEIM, KARSTEN;
KOSCHINSKY, THEODOR;
Pfützner, Andreas

Publication type:

commentary

CVOT summit report 2024: new cardiovascular, kidney, and metabolic outcomes.

Published in:

Cardiovascular Diabetology, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12933-025-02700-0

By:

Schnell, Oliver;
Almandoz, Jaime;
Anderson, Lisa;
Barnard-Kelly, Katharine;
Battelino, Tadej;
Blüher, Matthias;
Busetto, Luca;
Catrinou, Doina;
Ceriello, Antonio;
Cos, Xavier;
Danne, Thomas;
Dayan, Colin M.;
Del Prato, Stefano;
Fernández-Fernández, Beatriz;
Fioretto, Paola;
Forst, Thomas;
Gavin, James R.;
Giorgino, Francesco;
Groop, Per-Henrik;
Harsch, Igor A.

Publication type:

Article

New strategies to improve clinical outcomes for diabetic kidney disease.

Published in:

2022

By:

Forst, Thomas;
Mathieu, Chantal;
Giorgino, Francesco;
Wheeler, David C.;
Papanas, Nikolaos;
Schmieder, Roland E.;
Halabi, Atef;
Schnell, Oliver;
Streckbein, Marina;
Tuttle, Katherine R.

Publication type:

journal article

Effect of changes in metabolic enzymes and transporters on drug metabolism in the context of liver disease: Impact on pharmacokinetics and drug–drug interactions.

Published in:

British Journal of Clinical Pharmacology, 2024, v. 90, n. 4, p. 942, doi. 10.1111/bcp.15990

By:

Armani, Sara;
Geier, Andreas;
Forst, Thomas;
Merle, Uta;
Alpers, David H.;
Lunnon, Martin W.

Publication type:

Article

Anti-diabetic treatment regulates pro-fibrotic TGF-ß serum levels in type 2 diabetics.

Published in:

Diabetology & Metabolic Syndrome, 2013, v. 5, n. 1, p. 1, doi. 10.1186/1758-5996-5-48

By:

Pscherer, Stefan;
Freude, Thomas;
Forst, Thomas;
Nussler, Andreas K.;
Braun, Karl F.;
Ehnert, Sabrina

Publication type:

Article

Association of sulphonylurea treatment with all-cause and cardiovascular mortality: A systematic review and meta-analysis of observational studies.

Published in:

Diabetes & Vascular Disease Research, 2013, v. 10, n. 4, p. 302, doi. 10.1177/1479164112465442

By:

Forst, Thomas;
Hanefeld, Markolf;
Jacob, Stephan;
Moeser, Guido;
Schwenk, Gero;
Pfützner, Andreas;
Haupt, Axel

Publication type:

Article

Increased prevalence of cardiovascular disease and risk biomarkers in patients with unknown type 2 diabetes visiting cardiology specialists: results from the DIASPORA study.

Published in:

Diabetes & Vascular Disease Research, 2010, v. 7, n. 2, p. 145, doi. 10.1177/1479164109358241

By:

Schöndorf, Thomas;
Lübben, Georg;
Karagiannis, Efstrathios;
Erdmann, Erland;
Forst, Thomas;
Pfützner, Andreas

Publication type:

Article

Investigation of the vascular and pleiotropic effects of atorvastatin and pioglitazone in a population at high cardiovascular risk.

Published in:

Diabetes & Vascular Disease Research, 2008, v. 5, n. 4, p. 298, doi. 10.3132/dvdr.2008.043

By:

Forst, Thomas;
Wilhelm, Birgit;
Pfützner, Andreas;
Fuchs, Winfried;
Lehmann, Ute;
Schaper, Frank;
Weber, Matthias;
Müller, Jürgen;
Konrad, Thomas;
Hanefeld, Markolf

Publication type:

Article

Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNA) in insulinomas: Indications and clinical relevance in a single investigator cohort of 47 patients.

Published in:

Endocrine (1355008X), 2017, v. 56, n. 1, p. 158, doi. 10.1007/s12020-016-1179-z

By:

Kann, Peter;
Moll, Roland;
Bartsch, Detlef;
Pfützner, Andreas;
Forst, Thomas;
Tamagno, Gianluca;
Goebel, Joachim;
Fourkiotis, Verena;
Bergmann, Simona;
Collienne, Maike

Publication type:

Article

A practical approach to the clinical challenges in initiation of basal insulin therapy in people with type 2 diabetes.

Published in:

Diabetes/Metabolism Research & Reviews, 2021, v. 37, n. 6, p. 1, doi. 10.1002/dmrr.3418

By:

Forst, Thomas;
Choudhary, Pratik;
Schneider, Doron;
Linetzky, Bruno;
Pozzilli, Paolo

Publication type:

Article

Resolution of adiponectin oligomers in human plasma using free flow electrophoresis.

Published in:

Archives of Physiology & Biochemistry, 2009, v. 115, n. 5, p. 267, doi. 10.3109/13813450903307814

By:

Foucher, Aude L.;
Hartmann, Kristina;
Hauptmann, Monika;
Wildgruber, Robert;
Safinowski, Michael;
Forst, Thomas;
Pfützner, Andreas;
Gelfand, Craig A.;
Nissum, Mikkel

Publication type:

Article

Development and Validation of a High-Throughput Screening Method for Two Polymorphisms in the Serotonin Transporter Gene.

Published in:

Molecular Diagnosis & Therapy, 2009, v. 13, n. 1, p. 25, doi. 10.1007/BF03256312

By:

Eidens, Moritz;
Weise, Alexander;
Prause, Stefan;
Dahmen, Norbert;
Wunsch, Annette;
Weber, Mathias Max;
Forst, Thomas;
Pfützner, Andreas

Publication type:

Article

Pioglitazone: an antidiabetic drug with cardiovascular therapeutic effects.

Published in:

Expert Review of Cardiovascular Therapy, 2006, v. 4, n. 4, p. 445, doi. 10.1586/14779072.4.4.445

By:

Pfützner, Andreas;
Schneider, Christian A.;
Forst, Thomas

Publication type:

Article

CVOT Summit Report 2023: new cardiovascular, kidney, and metabolic outcomes.

Published in:

Cardiovascular Diabetology, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12933-024-02180-8

By:

Schnell, Oliver;
Barnard-Kelly, Katharine;
Battelino, Tadej;
Ceriello, Antonio;
Larsson, Helena Elding;
Fernández-Fernández, Beatriz;
Forst, Thomas;
Frias, Juan-Pablo;
Gavin III, James R.;
Giorgino, Francesco;
Groop, Per-Henrik;
Heerspink, Hiddo J. L.;
Herzig, Stephan;
Hummel, Michael;
Huntley, George;
Ibrahim, Mahmoud;
Itzhak, Baruch;
Jacob, Stephan;
Ji, Linong;
Kosiborod, Mikhail

Publication type:

Article

CVOT Summit 2022 Report: new cardiovascular, kidney, and glycemic outcomes.

Published in:

Cardiovascular Diabetology, 2023, v. 22, n. 1, p. 1, doi. 10.1186/s12933-023-01788-6

By:

Schnell, Oliver;
Battelino, Tadej;
Bergenstal, Richard;
Birkenfeld, Andreas L.;
Ceriello, Antonio;
Cheng, Alice;
Davies, Melanie;
Edelman, Steve;
Forst, Thomas;
Giorgino, Francesco;
Green, Jennifer;
Groop, Per-Henrik;
Hadjadj, Samy;
J.L.Heerspink, Hiddo;
Hompesch, Marcus;
Izthak, Baruch;
Ji, Linong;
Kanumilli, Naresh;
Mankovsky, Boris;
Mathieu, Chantal

Publication type:

Article

Vildagliptin versus insulin in patients with type 2 diabetes mellitus inadequately controlled with sulfonylurea: results from a randomized, 24 week study.

Published in:

Current Medical Research & Opinion, 2015, v. 31, n. 6, p. 1079, doi. 10.1185/03007995.2015.1039936

By:

Forst, Thomas;
Koch, Cornelia;
Dworak, Markus

Publication type:

Article

Differentiation of Adipocyte-Derived Adult Mesenchymal Stem Cells into Insulin Expressing Cells In Vitro.

Published in:

Diabetes, 2007, v. 56, p. A683

By:

Pfützner, Andreas;
Rutkowski, Andrej;
Tappe, Mareike;
Roitzheim, Barbara;
Pansky, Andreas;
Forst, Thomas;
Tobiasch, Edda

Publication type:

Article

Short Term Treatment with Pioglitazone Improves Adiponectin and Intact Proinsulin Levels in Type 2 Diabetic Patients with Coronary Heart Disease.

Published in:

Diabetes, 2007, v. 56, p. A669

By:

Hohberg, Cloth;
Forst, Thomas;
Lübben, Georg;
Karagiannis, Efstrathios;
Schöndorf, Thomas;
Pfützner, Andreas

Publication type:

Article

IRIS V-Study: Pioglitazone Reduces High-Sensitivity CRP Values in Patients with Type 2 Diabetes Under Daily Routine Conditions.

Published in:

Diabetes, 2007, v. 56, p. A586

By:

Pfützner, Andreas;
Schöndorf, Thomas;
Lübben, Georg;
Flannery, Manja;
Grabellus, Martin;
Roth, Werner;
Forst, Thomas;
Karagiannis, Efstrathios

Publication type:

Article