Works matching AU Fokin, Valery V.

Results: 47

Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging.

Published in:

Archives of Toxicology, 2025, v. 99, n. 5, p. 2107, doi. 10.1007/s00204-025-03985-6

By:

Čadež, Tena;
Maček Hrvat, Nikolina;
Šinko, Goran;
Kalisiak, Jarosław;
Radić, Zoran;
Fokin, Valery V.;
Sharpless, Karl Barry;
Taylor, Palmer;
Kovarik, Zrinka

Publication type:

Article

Copper(I)-Catalyzed Cycloaddition of Bismuth(III) Acetylides with Organic Azides: Synthesis of Stable Triazole Anion Equivalents.

Published in:

Angewandte Chemie, 2013, v. 125, n. 49, p. 13275, doi. 10.1002/ange.201306192

By:

Worrell, Brady T.;
Ellery, Shelby P.;
Fokin, Valery V.

Publication type:

Article

Sulfonyl-1,2,3-Triazoles: Convenient Synthones for Heterocyclic Compounds.

Published in:

Angewandte Chemie, 2013, v. 125, n. 5, p. 1547, doi. 10.1002/ange.201206388

By:

Zibinsky, Mikhail;
Fokin, Valery V.

Publication type:

Article

Ring Expansion and Rearrangements of Rhodium(II) Azavinyl Carbenes.

Published in:

Angewandte Chemie, 2012, v. 124, n. 52, p. 13231, doi. 10.1002/ange.201207820

By:

Selander, Nicklas;
Worrell, Brady T.;
Fokin, Valery V.

Publication type:

Article

Halogen Exchange (Halex) Reaction of 5-Iodo-1,2,3-triazoles: Synthesis and Applications of 5-Fluorotriazoles.

Published in:

Angewandte Chemie, 2012, v. 124, n. 47, p. 11961, doi. 10.1002/ange.201204979

By:

Worrell, Brady T.;
Hein, Jason E.;
Fokin, Valery V.

Publication type:

Article

Click and Pick: Identification of Sialoside Analogues for Siglec-Based Cell Targeting.

Published in:

Angewandte Chemie, 2012, v. 124, n. 44, p. 11176, doi. 10.1002/ange.201205831

By:

Rillahan, Cory D.;
Schwartz, Erik;
McBride, Ryan;
Fokin, Valery V.;
Paulson, James C.

Publication type:

Article

Practical Synthesis of Amides from In Situ Generated Copper(I) Acetylides and Sulfonyl AzidesWe thank the National Institutes of Health, the National Institute of General Medical Sciences (GM28384), the Skaggs Institute for Chemical Biology, and Pfizer, Inc. for financial support. We also thank Prof. K. B. Sharpless, Prof. M. G. Finn, and Dr. M. Whiting for valuable advice and stimulating discussions.

Published in:

Angewandte Chemie, 2006, v. 118, n. 19, p. 3226, doi. 10.1002/ange.200503805

By:

Michael P. Cassidy;
Jessica Raushel;
Valery V. Fokin

Publication type:

Article

Copper-Catalyzed Reaction Cascade: Direct Conversion of Alkynes into N-Sulfonylazetidin-2-iminesWe thank the National Institutes of Health, the National Institute of General Medical Sciences (GM28384), the Skaggs Institute for Chemical Biology, and Pfizer, Inc. for financial support. We also thank Prof. K. B. Sharpless for valuable advice and stimulating discussions.

Published in:

Angewandte Chemie, 2006, v. 118, n. 19, p. 3229, doi. 10.1002/ange.200503936

By:

Matthew Whiting;
Valery V. Fokin

Publication type:

Article

Inhibitors of HIV-1 Protease by Using In Situ Click ChemistryWe thank the National Institute of General Medical Sciences, the National Institutes of Health (GM048870), the Skaggs Institute for Chemical Biology, and the W. M. Keck Foundation (K.B.S.) for financial support.

Published in:

Angewandte Chemie, 2006, v. 118, n. 9, p. 1463, doi. 10.1002/ange.200502161

By:

Matthew Whiting;
John Muldoon;
Ying-Chuan Lin;
Steven M. Silverman;
William Lindstrom;
Arthur J. Olson;
Hartmuth C. Kolb;
M. G. Finn;
K. Barry Sharpless;
John H. Elder;
Valery V. Fokin

Publication type:

Article

Titelbild: “On Water”: Unique Reactivity of Organic Compounds in Aqueous Suspension (Angew. Chem. 21/2005).

Published in:

Angewandte Chemie, 2005, v. 117, n. 21, p. 3219, doi. 10.1002/ange.200590069

By:

Sridhar Narayan;
John Muldoon;
M. G. Finn;
Valery V. Fokin;
Hartmuth C. Kolb;
K. Barry Sharpless

Publication type:

Article

“On Water”: Unique Reactivity of Organic Compounds in Aqueous SuspensionWe thank Dr. Vladislav Litosh for carrying out preliminary work. Support from the National Institutes of Health, National Institute of General Medical Sciences (GM 28384), the National Science Foundation (CHE9985553), the Skaggs Institute for Chemical Biology, and the W. M. Keck Foundation is gratefully acknowledged. S.N. thanks the Skaggs Institute for a postdoctoral fellowship. We also thank Dr. Suresh Suri, Edwards Air Force Base, California, for a generous gift of quadricyclane. We urge our fellow chemists to float their problematic reactions on water and to send observations of success or failure to us at onwater@scripps.edu for public dissemination with attribution.

Published in:

Angewandte Chemie, 2005, v. 117, n. 21, p. 3339, doi. 10.1002/ange.200462883

By:

Sridhar Narayan;
John Muldoon;
M. G. Finn;
Valery V. Fokin;
Hartmuth C. Kolb;
K. Barry Sharpless

Publication type:

Article

Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis.

Published in:

PLoS Neglected Tropical Diseases, 2020, v. 14, n. 4, p. 1, doi. 10.1371/journal.pntd.0008224

By:

Lauwaet, Tineke;
Miyamoto, Yukiko;
Ihara, Sozaburo;
Le, Christine;
Kalisiak, Jarosław;
Korthals, Keith;
Ghassemian, Majid;
Smith, Diane K.;
Sharpless, K. Barry;
Fokin, Valery V.;
Eckmann, Lars

Publication type:

Article

Mechanism of the Ligand-Free CuI-Catalyzed Azide–Alkyne Cycloaddition ReactionWe thank the Skaggs Institute for Chemical Biology for support of this work.

Published in:

Angewandte Chemie, 2005, v. 117, n. 15, p. 2250, doi. 10.1002/ange.200461496

By:

Valentin O. Rodionov;
Valery V. Fokin;
M. G. Finn

Publication type:

Article

Efficiency and Fidelity in a Click-Chemistry Route to Triazole Dendrimers by the Copper(I)-Catalyzed Ligation of Azides and AlkynesWe thank the National Institute of General Medical Sciences, the National Institutes of Health (GM 28284), the National Science Foundation (CHE-9985553), the W. M. Keck Foundation, the Skaggs Institute for Chemical Biology, the MRSEC Program of the National Science Foundation (award no. DMR-0213618 for the Center for Polymeric Interfaces and Macromolecular Assemblies), the NIRT Program of the National Science Foundation (grant no. 0210247), IBM Corporation, DOE-BES, and NSF International/DAAD for financial support. We are also grateful to Prof. M. G. Finn for helpful discussions.

Published in:

Angewandte Chemie, 2004, v. 116, n. 30, p. 4018, doi. 10.1002/ange.200454078

By:

Peng Wu;
Alina K. Feldman;
Anne K. Nugent;
Craig J. Hawker;
Arnulf Scheel;
Brigitte Voit;
Jeffrey Pyun;
Jean M. J. Fréchet;
K. Barry Sharpless;
Valery V. Fokin

Publication type:

Article

Titelbild: Efficiency and Fidelity in a Click-Chemistry Route to Triazole Dendrimers by the Copper(I)-Catalyzed Ligation of Azides and Alkynes (Angew. Chem. 30/2004).

Published in:

Angewandte Chemie, 2004, v. 116, n. 30, p. 3951, doi. 10.1002/ange.200490100

By:

Peng Wu;
Alina K. Feldman;
Anne K. Nugent;
Craig J. Hawker;
Arnulf Scheel;
Brigitte Voit;
Jeffrey Pyun;
Jean M. J. Fréchet;
K. Barry Sharpless;
Valery V. Fokin

Publication type:

Article

From BACE1 Inhibitor to Multifunctionality of Tryptoline and Tryptamine Triazole Derivatives for Alzheimer's Disease.

Published in:

Molecules, 2012, v. 17, n. 7, p. 8312, doi. 10.3390/molecules17078312

By:

Jiaranaikulwanitch, Jutamas;
Govitrapong, Piyarat;
Fokin, Valery V.;
Vajragupta, Opa

Publication type:

Article

Synthesis of Indole-Derived Allocolchicine Congeners through Pd-Catalyzed Intramolecular C-H Arylation Reaction.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 29, p. 6481, doi. 10.1002/ejoc.201402850

By:

Sitnikov, Nikolay S.;
Kokisheva, Antonina S.;
Fukin, Georgy K.;
Neudörfl, Jörg‐Martin;
Sutorius, Hannah;
Prokop, Aram;
Fokin, Valery V.;
Schmalz, Hans‐Günther;
Fedorov, Alexey Yu.

Publication type:

Article

Rapid Diversity-Oriented Synthesis in Microtiter Plates for In Situ Screening of HIV Protease Inhibitors.

Published in:

ChemBioChem, 2003, v. 4, n. 11, p. 1246, doi. 10.1002/cbic.200300724

By:

Ashraf Brik;
John Muldoon;
Ying-Chuan Lin;
John H. Elder;
David S. Goodsell;
Arthur J. Olson;
Valery V. Fokin;
K. Bary Sharpless;
Chi-Huey Wong

Publication type:

Article

SuFEx-Based Synthesis of Polysulfates.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 36, p. 9466, doi. 10.1002/anie.201403758

By:

Dong, Jiajia;
Sharpless, K. Barry;
Kwisnek, Luke;
Oakdale, James S.;
Fokin, Valery V.

Publication type:

Article

Catalytic Asymmetric Transannulation of N H-1,2,3-Triazoles with Olefins.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 13, p. 3452, doi. 10.1002/anie.201306706

By:

Kwok, Sen Wai;
Zhang, Li;
Grimster, Neil P.;
Fokin, Valery V.

Publication type:

Article

Copper(I)-Catalyzed Cycloaddition of Bismuth(III) Acetylides with Organic Azides: Synthesis of Stable Triazole Anion Equivalents.

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 49, p. 13037, doi. 10.1002/anie.201306192

By:

Worrell, Brady T.;
Ellery, Shelby P.;
Fokin, Valery V.

Publication type:

Article

SuFEx-Based Synthesis of Polysulfates.

Published in:

Angewandte Chemie, 2014, v. 126, n. 36, p. 9620, doi. 10.1002/ange.201403758

By:

Dong, Jiajia;
Sharpless, K. Barry;
Kwisnek, Luke;
Oakdale, James S.;
Fokin, Valery V.

Publication type:

Article

Catalytic Asymmetric Transannulation of N H-1,2,3-Triazoles with Olefins.

Published in:

Angewandte Chemie, 2014, v. 126, n. 13, p. 3520, doi. 10.1002/ange.201306706

By:

Kwok, SEN Wai;
Zhang, Li;
Grimster, Neil P.;
Fokin, Valery V.

Publication type:

Article

Sulfonyl-1,2,3-Triazoles: Convenient Synthones for Heterocyclic Compounds.

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 5, p. 1507, doi. 10.1002/anie.201206388

By:

Zibinsky, Mikhail;
Fokin, Valery V.

Publication type:

Article

Ring Expansion and Rearrangements of Rhodium(II) Azavinyl Carbenes.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 52, p. 13054, doi. 10.1002/anie.201207820

By:

Selander, Nicklas;
Worrell, Brady T.;
Fokin, Valery V.

Publication type:

Article

Halogen Exchange (Halex) Reaction of 5-Iodo-1,2,3-triazoles: Synthesis and Applications of 5-Fluorotriazoles.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 47, p. 11791, doi. 10.1002/anie.201204979

By:

Worrell, Brady T.;
Hein, Jason E.;
Fokin, Valery V.

Publication type:

Article

Click and Pick: Identification of Sialoside Analogues for Siglec-Based Cell Targeting.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 44, p. 11014, doi. 10.1002/anie.201205831

By:

Rillahan, Cory D.;
Schwartz, Erik;
McBride, Ryan;
Fokin, Valery V.;
Paulson, James C.

Publication type:

Article

Copper(I)-Catalyzed Cycloaddition of Organic Azides and 1-Iodoalkynes.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 43, p. 8018, doi. 10.1002/anie.200903558

By:

Hein, Jason E.;
Tripp, Jonathan C.;
Krasnova, Larissa B.;
Sharpless, K. Barry;
Fokin, Valery V.

Publication type:

Article

Iterative In Situ Click Chemistry Creates Antibody-like Protein-Capture Agents.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 27, p. 4944, doi. 10.1002/anie.200900488

By:

Agnew, Heather D.;
Rohde, Rosemary D.;
Millward, Steven W.;
Nag, Arundhati;
Yeo, Woon-Seok;
Hein, Jason E.;
Pitram, Suresh M.;
Tariq, Abdul Ahad;
Burns, Vanessa M.;
Krom, Russell J.;
Fokin, Valery V.;
Sharpless, K. Barry;
Heath, James R.

Publication type:

Article

Ruthenium-Catalyzed Cycloaddition of Nitrile Oxides and Alkynes: Practical Synthesis of Isoxazoles.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 43, p. 8285, doi. 10.1002/anie.200801920

By:

Grecian, Scott;
Fokin, Valery V.

Publication type:

Article

Ruthenium-Catalyzed Cycloadditions of 1-Haloalkynes with Nitrile Oxides and Organic Azides: Synthesis of 4-Haloisoxazoles and 5-Halotriazoles.

Published in:

Chemistry - A European Journal, 2014, v. 20, n. 35, p. 11101, doi. 10.1002/chem.201402559

By:

Oakdale, James S.;
Sit, Rakesh K.;
Fokin, Valery V.

Publication type:

Article

Copper-Catalyzed Synthesis of N-Sulfonyl-1,2,3-triazoles: Controlling Selectivity.

Published in:

Angewandte Chemie International Edition, 2007, v. 46, n. 10, p. 1730, doi. 10.1002/anie.200604241

By:

Yoo, Eun Jeong;
Ahlquist, Mårten;
Kim, Seok Hwan;
Bae, Imhyuck;
Fokin, Valery V.;
Sharpless, K. Barry;
Chang, Sukbok

Publication type:

Article

Copper-Catalyzed Reaction Cascade: Direct Conversion of Alkynes into N-Sulfonylazetidin-2-iminesWe thank the National Institutes of Health, the National Institute of General Medical Sciences (GM28384), the Skaggs Institute for Chemical Biology, and Pfizer, Inc. for financial support. We also thank Prof. K. B. Sharpless for valuable advice and stimulating discussions.

Published in:

Angewandte Chemie International Edition, 2006, v. 45, n. 19, p. 3157, doi. 10.1002/anie.200503936

By:

Matthew Whiting;
Valery V. Fokin

Publication type:

Article

Practical Synthesis of Amides from In Situ Generated Copper(I) Acetylides and Sulfonyl AzidesWe thank the National Institutes of Health, the National Institute of General Medical Sciences (GM28384), the Skaggs Institute for Chemical Biology, and Pfizer, Inc. for financial support. We also thank Prof. K. B. Sharpless, Prof. M. G. Finn, and Dr. M. Whiting for valuable advice and stimulating discussions.

Published in:

Angewandte Chemie International Edition, 2006, v. 45, n. 19, p. 3154, doi. 10.1002/anie.200503805

By:

Michael P. Cassidy;
Jessica Raushel;
Valery V. Fokin

Publication type:

Article

Inhibitors of HIV-1 Protease by Using In Situ Click ChemistryWe thank the National Institute of General Medical Sciences, the National Institutes of Health (GM048870), the Skaggs Institute for Chemical Biology, and the W. M. Keck Foundation (K.B.S.) for financial support.

Published in:

Angewandte Chemie International Edition, 2006, v. 45, n. 9, p. 1435, doi. 10.1002/anie.200502161

By:

Matthew Whiting;
John Muldoon;
Ying-Chuan Lin;
Steven M. Silverman;
William Lindstrom;
Arthur J. Olson;
Hartmuth C. Kolb;
M. G. Finn;
K. Barry Sharpless;
John H. Elder;
Valery V. Fokin

Publication type:

Article

Cover Picture: “On Water”: Unique Reactivity of Organic Compounds in Aqueous Suspension (Angew. Chem. Int. Ed. 21/2005).

Published in:

Angewandte Chemie International Edition, 2005, v. 44, n. 21, p. 3157, doi. 10.1002/anie.200590069

By:

Sridhar Narayan;
John Muldoon;
M. G. Finn;
Valery V. Fokin;
Hartmuth C. Kolb;
K. Barry Sharpless

Publication type:

Article

“On Water”: Unique Reactivity of Organic Compounds in Aqueous SuspensionWe thank Dr. Vladislav Litosh for carrying out preliminary work. Support from the National Institutes of Health, National Institute of General Medical Sciences (GM 28384), the National Science Foundation (CHE9985553), the Skaggs Institute for Chemical Biology, and the W. M. Keck Foundation is gratefully acknowledged. S.N. thanks the Skaggs Institute for a postdoctoral fellowship. We also thank Dr. Suresh Suri, Edwards Air Force Base, California, for a generous gift of quadricyclane. We urge our fellow chemists to float their problematic reactions on water and to send observations of success or failure to us at onwater@scripps.edu for public dissemination with attribution.

Published in:

Angewandte Chemie International Edition, 2005, v. 44, n. 21, p. 3275, doi. 10.1002/anie.200462883

By:

Sridhar Narayan;
John Muldoon;
M. G. Finn;
Valery V. Fokin;
Hartmuth C. Kolb;
K. Barry Sharpless

Publication type:

Article

Mechanism of the Ligand-Free CuI-Catalyzed AzideAlkyne Cycloaddition ReactionWe thank the Skaggs Institute for Chemical Biology for support of this work.

Published in:

Angewandte Chemie International Edition, 2005, v. 44, n. 15, p. 2210, doi. 10.1002/anie.200461496

By:

Valentin O. Rodionov;
Valery V. Fokin;
M. G. Finn

Publication type:

Article

Efficiency and Fidelity in a Click-Chemistry Route to Triazole Dendrimers by the Copper(I)-Catalyzed Ligation of Azides and AlkynesWe thank the National Institute of General Medical Sciences, the National Institutes of Health (GM 28284), the National Science Foundation (CHE-9985553), the W. M. Keck Foundation, the Skaggs Institute for Chemical Biology, the MRSEC Program of the National Science Foundation (award no. DMR-0213618 for the Center for Polymeric Interfaces and Macromolecular Assemblies), the NIRT Program of the National Science Foundation (grant no. 0210247), IBM Corporation, DOE-BES, and NSF International/DAAD for financial support. We are also grateful to Prof. M. G. Finn for helpful discussions.

Published in:

Angewandte Chemie International Edition, 2004, v. 43, n. 30, p. 3928, doi. 10.1002/anie.200454078

By:

Peng Wu;
Alina K. Feldman;
Anne K. Nugent;
Craig J. Hawker;
Arnulf Scheel;
Brigitte Voit;
Jeffrey Pyun;
Jean M. J. Fréchet;
K. Barry Sharpless;
Valery V. Fokin

Publication type:

Article

Cover Picture: Efficiency and Fidelity in a Click-Chemistry Route to Triazole Dendrimers by the Copper(I)-Catalyzed Ligation of Azides and Alkynes (Angew. Chem. Int. Ed. 30/2004).

Published in:

Angewandte Chemie International Edition, 2004, v. 43, n. 30, p. 3863, doi. 10.1002/anie.200490100

By:

Peng Wu;
Alina K. Feldman;
Anne K. Nugent;
Craig J. Hawker;
Arnulf Scheel;
Brigitte Voit;
Jeffrey Pyun;
Jean M. J. Fréchet;
K. Barry Sharpless;
Valery V. Fokin

Publication type:

Article

A Stepwise Huisgen Cycloaddition Process: Copper( I)-Catalyzed Regioselective 'Ligation' of Azides and Terminal Alkynes.

Published in:

Angewandte Chemie International Edition, 2002, v. 41, n. 14, p. 2596, doi. 10.1002/1521-3773(20020715)41:14<2596::AID-ANIE2596>3.0.CO;2-4

By:

Rostovtsev, Vsevolod V.;
Green, Luke G.;
Fokin, Valery V.;
Sharpless, K. Barry

Publication type:

Article

A New Approach to Osmium-Catalyzed Asymmetric Dihydroxylation and Aminohydroxylation of Olefins.

Published in:

Angewandte Chemie International Edition, 2002, v. 41, n. 3, p. 472, doi. 10.1002/1521-3773(20020201)41:3<472::AID-ANIE472>3.0.CO;2-7

By:

Andersson, Malin A.;
Epple, Robert;
Fokin, Valery V.;
Sharpless, K. Barry

Publication type:

Article

A Practical and Highly Efficient Aminohydroxylation of Unsaturated Carboxylic Acids.

Published in:

Angewandte Chemie International Edition, 2001, v. 40, n. 18, p. 3455, doi. 10.1002/1521-3773(20010917)40:18<3455::AID-ANIE3455>3.0.CO;2-I

By:

Fokin, Valery V.;
Sharpless, K. Barry

Publication type:

Article

Sulfuryl Fluoride Mediated Synthesis of Amides and Amidines from Ketoximes via Beckmann Rearrangement.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 46, p. 10402, doi. 10.1002/chem.201905358

By:

Gurjar, Jitendra;
Fokin, Valery V.

Publication type:

Article

Reversal of Tabun Toxicity Enabled by a Triazole‐Annulated Oxime Library—Reactivators of Acetylcholinesterase.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 16, p. 4100, doi. 10.1002/chem.201805051

By:

Kovarik, Zrinka;
Kalisiak, Jarosław;
Hrvat, Nikolina Maček;
Katalinić, Maja;
Zorbaz, Tamara;
Žunec, Suzana;
Green, Carol;
Radić, Zoran;
Fokin, Valery V.;
Sharpless, K. Barry;
Taylor, Palmer

Publication type:

Article

Sulfuryl Fluoride Mediated Conversion of Aldehydes to Nitriles.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 8, p. 1906, doi. 10.1002/chem.201805175

By:

Gurjar, Jitendra;
Bater, Jorick;
Fokin, Valery V.

Publication type:

Article

Osmium-Catalyzed Dihydroxylation of Olefins in Acidic Media: Old Process, New Tricks.

Published in:

Advanced Synthesis & Catalysis, 2002, v. 344, n. 3/4, p. 421, doi. 10.1002/1615-4169(200206)344:3/4<421::AID-ADSC421>3.0.CO;2-F

By:

Dupau, Philippe;
Epple, Robert;
Thomas, Allen A.;
Fokin, Valery V.;
Sharpless, K. Barry

Publication type:

Article