Works by Fok, Kin Lam

Results: 29

CFTR mediates bicarbonate-dependent activation of miR-125b in preimplantation embryo development.

Published in:

Cell Research, 2012, v. 22, n. 10, p. 1453, doi. 10.1038/cr.2012.88

By:

Lu, Yong Chao;
Chen, Hui;
Fok, Kin Lam;
Tsang, Lai Ling;
Yu, Mei Kuen;
Zhang, Xiao Hu;
Chen, Jing;
Jiang, Xiaohua;
Chung, Yiu Wa;
Ma, Alvin Chun Hang;
Leung, Anskar Yu Hung;
Huang, He Feng;
Chan, Hsiao Chang

Publication type:

Article

STK31 Maintains the Undifferentiated State of Colon Cancer Cells.

Published in:

Carcinogenesis, 2012, v. 33, n. 11, p. 2044, doi. 10.1093/carcin/bgs246

By:

Fok, Kin Lam;
Chung, Chin Man;
Yi, Shao Qiong;
Jiang, Xiaohua;
Sun, Xiao;
Chen, Hao;
Chen, Yang Chao;
Kung, Hsiang-Fu;
Tao, Qian;
Diao, Ruiying;
Chan, Henry;
Zhang, Xiao Hu;
Chung, Yiu Wa;
Cai, Zhiming;
Chang Chan, Hsiao

Publication type:

Article

A suppressor of multiple extracellular matrix-degrading proteases and cancer metastasis.

Published in:

Journal of Cellular & Molecular Medicine, 2009, v. 13, n. 9b, p. 4034, doi. 10.1111/j.1582-4934.2008.00576.x

By:

Lan lan Yin;
Chin Man Chung;
Jie Chen;
Kin Lam Fok;
Chuen Pei Ng;
Rui Rui Jia;
Xuan Ren;
Jiannong Zhou;
Tong Zhang;
Xiao Hang Zhao;
Min Lin;
Hu Zhu;
Xiao Hu Zhang;
Lai Ling Tsang;
Ye Bi;
Zuomin Zhou;
Fugen Mo;
Nathalie Wong;
Yiu Wa Chung;
Jiahao Sha

Publication type:

Article

Lymphocyte CFTR promotes epithelial bicarbonate secretion for bacterial killing.

Published in:

Journal of Cellular Physiology, 2012, v. 227, n. 12, p. 3887, doi. 10.1002/jcp.24101

By:

Tang, Xiao Xiao;
Fok, Kin Lam;
Chen, Hao;
Chan, Kay Sheung;
Tsang, Lai Ling;
Rowlands, Dewi Kenneth;
Zhang, Xiao Hu;
Da Dong, Jian;
Ruan, Ye Chun;
Jiang, Xiaohua;
Yu, Sidney Siu Bun;
Chung, Yiu Wa;
Chan, Hsiao Chang

Publication type:

Article

Spatio-temporal landscape of mouse epididymal cells and specific mitochondria-rich segments defined by large-scale single-cell RNA-seq.

Published in:

Cell Discovery, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41421-021-00260-7

By:

Shi, Jianwu;
Fok, Kin Lam;
Dai, Pengyuan;
Qiao, Feng;
Zhang, Mengya;
Liu, Huage;
Sang, Mengmeng;
Ye, Mei;
Liu, Yang;
Zhou, Yiwen;
Wang, Chengniu;
Sun, Fei;
Xie, Gangcai;
Chen, Hao

Publication type:

Article

CSE1L/CAS regulates cell proliferation through CDK signalling in mouse spermatogenesis.

Published in:

Cell Proliferation, 2022, v. 55, n. 11, p. 1, doi. 10.1111/cpr.13334

By:

Shi, Jianwu;
Qiao, Feng;
Ye, Mei;
Jiang, Ting;
Liu, Jianni;
Zhang, Mengya;
Xie, Gangcai;
Fok, Kin Lam;
Li, Xiaofeng;
Chen, Hao

Publication type:

Article

Interfering with CSE1L/CAS inhibits tumour growth via C3 in triple‐negative breast cancer.

Published in:

Cell Proliferation, 2022, v. 55, n. 5, p. 1, doi. 10.1111/cpr.13226

By:

Ye, Mei;
Chen, Yufei;
Liu, Jianni;
Tian, Jiawei;
Wang, Xunda;
Fok, Kin Lam;
Shi, Jianwu;
Chen, Hao

Publication type:

Article

The repertoire of testicular extracellular vesicle cargoes and their involvement in inter-compartmental communication associated with spermatogenesis.

Published in:

BMC Biology, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12915-022-01268-5

By:

Choy, Kathleen Hoi Kei;
Chan, Sze Yan;
Lam, William;
Jin, Jing;
Zheng, Tingting;
Law, Tin Yu Samuel;
Yu, Sidney Siubun;
Wang, Weiping;
Li, Linxian;
Xie, Gangcai;
Yim, Howard Chi Ho;
Chen, Hao;
Fok, Ellis Kin Lam

Publication type:

Article

CFTR is required for cellular entry and internalization of Chlamydia trachomatis.

Published in:

Cell Biology International, 2010, v. 34, n. 6, p. 593, doi. 10.1042/CBI20090227

By:

Ajonuma, Chukwuemeka Louis;
Fok, Lam Kin;
Ho, Sze Lok;
Chan, Sheung Kay Paul;
Chow, Pak H.;
Tsang, Ling Lai;
Wong, Yan Hau Connie;
Chen, Jie;
Li, Shen;
Rowlands, Kenneth Dewi;
Chung, Wa Yiu;
Chan, Chang Hsiao

Publication type:

Article

Involvement of cystic fibrosis transmembrane conductance regulator in infection-induced edema

Published in:

Cell Biology International, 2008, v. 32, n. 7, p. 801, doi. 10.1016/j.cellbi.2008.03.010

By:

Ajonuma, Louis Chukwuemeka;
He, Qiong;
Sheung Chan, Paul Kay;
Yu Ng, Ernest Hung;
Fok, Kin Lam;
Yan Wong, Connie Hau;
Tsang, Lai Ling;
Ho, Lok Sze;
Lau, Miu Ching;
Huang, Hong Yi;
Yang, Dong Zi;
Rowlands, Dewi Kenneth;
Tang, Xiao Xiao;
Zhang, Xiao Hu;
Chung, Yiu Wa;
Chan, Hsiao Chang

Publication type:

Article

Herbal extract ECBRC-AG and its active intgredient reduces HPA axis funtion by inhibiting PVN neurons activity through T-type calcium channels

Published in:

2008

By:

Zhang, Xiao Hu;
Rowlands, Dewi Kenneth;
Ma, Ze Gang;
Gou, Yu Lin;
Tsang, Lai Ling;
Wong, Hau Yan;
Fok, Kin Lam;
Chung, Yiu Wa;
Mu, Li;
Chan, Hsiao Chang

Publication type:

Abstract

The functional role of CFTR in spermatogenesis

Published in:

2008

By:

Xu, Wen Ming;
Chen, Wen Yin;
Dong, Hong Shan;
Fok, Kin Lam;
Zhou, Chen Xi;
Zhu, Hu;
Yan Wong, Connie Hau;
Chan, Hsiao Chang

Publication type:

Abstract

Differentiation of adult rat bone marrow stem cells into epithelial progenitor cells in culture

Published in:

Cell Biology International, 2006, v. 30, n. 10, p. 823, doi. 10.1016/j.cellbi.2006.06.004

By:

Shu, Chang;
Li, Ting Yu;
Tsang, Lai Ling;
Fok, Kin Lam;
Lo, Pui Shan;
Zhu, Jin Xia;
Ho, Lo Sze;
Chung, Yiu Wa;
Chan, Hsiao Chang

Publication type:

Article

Activation of the epithelial Na+ channel triggers prostaglandin E2 release and production required for embryo implantation.

Published in:

Nature Medicine, 2012, v. 18, n. 7, p. 1112, doi. 10.1038/nm.2771

By:

Ruan, Ye Chun;
Guo, Jing Hui;
Liu, Xinmei;
Zhang, Runju;
Tsang, Lai Ling;
Dong, Jian Da;
Chen, Hui;
Yu, Mei Kuen;
Jiang, Xiaohua;
Zhang, Xiao Hu;
Fok, Kin Lam;
Chung, Yiu Wa;
Huang, Hefeng;
Zhou, Wen Liang;
Chan, Hsiao Chang

Publication type:

Article

Involvement of cystic fibrosis transmembrane conductance regulator (CFTR) in the pathogenesis of hydrosalpinx induced by Chlamydia trachomatis infection.

Published in:

Journal of Obstetrics & Gynaecology Research, 2008, v. 34, n. 6, p. 923, doi. 10.1111/j.1447-0756.2008.00826.x

By:

Ajonuma, Louis Chukwuemeka;
Chan, Paul Kay Sheung;
Ng, Ernest Hung Yu;
Kin Lam Fok;
Wong, Connie Hau Yan;
Lai Ling Tsang;
Xiao Xiao Tang;
Lok Sze Ho;
Miu Ching Lau;
Chin Man Chung;
Qiong He;
Hong Yi Huang;
Dong Zi Yang;
Rowlands, Dewi Kenneth;
Yiu Wa Chung;
Hsiao Chang Chan

Publication type:

Article

Deficient human β-defensin 1 underlies male infertility associated with poor sperm motility and genital tract infection.

Published in:

Science Translational Medicine, 2014, v. 6, n. 249, p. 1, doi. 10.1126/scitranslmed.3009071

By:

Ruiying Diao;
Kin Lam Fok;
Hao Chen;
Mei Kuen Yu;
Yonggang Duan;
Chin Man Chung;
Zhao Li;
Hanwei Wu;
Zesong Li;
Hu Zhang;
Ziliang Ji;
Wanhua Zhen;
Chi Fai Ng;
Yaoting Gui;
Zhiming Cai;
Hsiao Chang Chan

Publication type:

Article

The Sperm Small RNA Transcriptome: Implications beyond Reproductive Disorder.

Published in:

2022

By:

Chan, Sze Yan;
Wan, Crystal Wing Tung;
Law, Tin Yu Samuel;
Chan, David Yiu Leung;
Fok, Ellis Kin Lam

Publication type:

Literature Review

Glucose-induced electrical activities and insulin secretion in pancreatic islet β-cells are modulated by CFTR.

Published in:

Nature Communications, 2014, v. 5, n. 7, p. 4420, doi. 10.1038/ncomms5420

By:

Guo, Jing Hui;
Chen, Hui;
Ruan, Ye Chun;
Zhang, Xue Lian;
Zhang, Xiao Hu;
Fok, Kin Lam;
Tsang, Lai Ling;
Yu, Mei Kuen;
Huang, Wen Qing;
Sun, Xiao;
Chung, Yiu Wa;
Jiang, Xiaohua;
Sohma, Yoshiro;
Chan, Hsiao Chang

Publication type:

Article

Defb19 regulates the migration of germ cell and is involved in male fertility.

Published in:

Cell & Bioscience, 2022, v. 12, n. 1, p. 1, doi. 10.1186/s13578-022-00924-1

By:

Jin, Jing;
Li, Xiaofeng;
Ye, Mei;
Qiao, Feng;
Chen, Hao;
Fok, Kin Lam

Publication type:

Article

Progenitor Cells Derived from Drain Waste Product of Open-Heart Surgery in Children.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 10, p. 1028, doi. 10.3390/jcm8071028

By:

Wong, Tak-Wah;
Kan, Chung-Dann;
Chiu, Wen-Tai;
Fok, Kin Lam;
Ruan, Ye Chun;
Jiang, Xiaohua;
Chen, Junjiang;
Kao, Chiu-Ching;
Chen, I-Yu;
Lin, Hui-Chun;
Chou, Chia-Hsuan;
Lin, Chou-Wen;
Yu, Chun-Keung;
Tsao, Stephanie;
Lee, Yi-Ping;
Chan, Hsiao Chang;
Wang, Jieh-Neng

Publication type:

Article

Progenitor Cells Derived from Drain Waste Product of Open-Heart Surgery in Children.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 7, p. 1028, doi. 10.3390/jcm8071028

By:

Wong, Tak-Wah;
Kan, Chung-Dann;
Chiu, Wen-Tai;
Fok, Kin Lam;
Ruan, Ye Chun;
Jiang, Xiaohua;
Chen, Junjiang;
Kao, Chiu-Ching;
Chen, I-Yu;
Lin, Hui-Chun;
Chou, Chia-Hsuan;
Lin, Chou-Wen;
Yu, Chun-Keung;
Tsao, Stephanie;
Lee, Yi-Ping;
Chan, Hsiao Chang;
Wang, Jieh-Neng

Publication type:

Article

Involvement of Cl−/HCO3− exchanger SLC26A3 and SLC26A6 in preimplantation embryo cleavage.

Published in:

Scientific Reports, 2016, p. 28402, doi. 10.1038/srep28402

By:

Lu, Yong Chao;
Yang, Jing;
Fok, Kin Lam;
Ye, Ying Hui;
Jin, Liang;
Chen, Zheng Yun;
Zhang, Xin Mei;
Huang, He Feng;
Chan, Hsiao Chang

Publication type:

Article

Defective CFTR-Dependent CREB Activation Results in Impaired Spermatogenesis and Azoospermia.

Published in:

PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0019120

By:

Wen Ming Xu;
Jing Chen;
Hui Chen;
Rui Ying Diao;
Kin Lam Fok;
Jian Da Dong;
Ting Ting Sun;
Wen Ying Chen;
Mei Kuen Yu;
Xiao Hu Zhang;
Lai Ling Tsang;
Ann Lau;
Qi Xian Shi;
Qing Hua hi;
Ping Bo Huang;
Hsiao Chang Chan

Publication type:

Article

Cryptorchidism-induced CFTR down-regulation results in disruption of testicular tight junctions through up-regulation of NF-κB/COX-2/PGE2.

Published in:

Human Reproduction, 2012, v. 27, n. 9, p. 2585, doi. 10.1093/humrep/des254

By:

Chen, Jing;
Fok, Kin Lam;
Chen, Hui;
Zhang, Xiao Hu;
Xu, Wen Ming;
Chan, Hsiao Chang

Publication type:

Article

CD147 regulates apoptosis in mouse spermatocytes but not spermatogonia.

Published in:

Human Reproduction, 2012, v. 27, n. 6, p. 1568, doi. 10.1093/humrep/des050

By:

Chen, Hao;
Fok, Kin Lam;
Jiang, Xiaohua;
Jiang, Jianli;
Chen, Zhinan;
Gui, Yaoting;
Chan, Hsiao Chang;
Cai, Zhiming

Publication type:

Article

The N501Y Mutation of SARS-CoV-2 Spike Protein Impairs Spindle Assembly in Mouse Oocytes.

Published in:

Reproductive Sciences, 2022, v. 29, n. 10, p. 2842, doi. 10.1007/s43032-021-00809-7

By:

Liu, Huage;
Shi, Jianwu;
Fok, Kin Lam;
Chen, Hao

Publication type:

Article

Dedifferentiation-Reprogrammed Mesenchymal Stem Cells with Improved Therapeutic Potential.

Published in:

Stem Cells, 2011, v. 29, n. 12, p. 2077, doi. 10.1002/stem.764

By:

Liu, Yang;
Jiang, Xiaohua;
Zhang, Xiaohu;
Chen, Rui;
Sun, Tingting;
Fok, Kin Lam;
Dong, Jianda;
Tsang, Lai Ling;
Yi, Shaoqiong;
Ruan, Yechun;
Guo, Jinghui;
Yu, Mei Kuen;
Tian, Yuemin;
Chung, Yiu Wa;
Yang, Mo;
Xu, Wenming;
Chung, Chin Man;
Li, Tingyu;
Chan, Hsiao Chang

Publication type:

Article

CD147 is required for matrix metalloproteinases-2 production and germ cell migration during spermatogenesis.

Published in:

Molecular Human Reproduction, 2011, v. 17, n. 7, p. 405, doi. 10.1093/molehr/gar013

By:

Chen, Hao;
Fok, Kin Lam;
Yu, Sidney;
Jiang, Jianli;
Chen, Zhinan;
Gui, Yaoting;
Cai, Zhiming;
Chan, Hsiao Chang

Publication type:

Article

Epigenetic regulation of CFTR during cancer development and implications in cancer treatment (1048.9).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.1048.9

By:

Huang, Wenqing;
Fok, Kin Lam;
Jiang, Xiao Hua;
Chan, Hsiao Chang

Publication type:

Article

Works by Fok, Kin Lam

CFTR mediates bicarbonate-dependent activation of miR-125b in preimplantation embryo development.

STK31 Maintains the Undifferentiated State of Colon Cancer Cells.

A suppressor of multiple extracellular matrix-degrading proteases and cancer metastasis.

Lymphocyte CFTR promotes epithelial bicarbonate secretion for bacterial killing.

Spatio-temporal landscape of mouse epididymal cells and specific mitochondria-rich segments defined by large-scale single-cell RNA-seq.

CSE1L/CAS regulates cell proliferation through CDK signalling in mouse spermatogenesis.

Interfering with CSE1L/CAS inhibits tumour growth via C3 in triple‐negative breast cancer.

The repertoire of testicular extracellular vesicle cargoes and their involvement in inter-compartmental communication associated with spermatogenesis.

CFTR is required for cellular entry and internalization of Chlamydia trachomatis.

Involvement of cystic fibrosis transmembrane conductance regulator in infection-induced edema

Herbal extract ECBRC-AG and its active intgredient reduces HPA axis funtion by inhibiting PVN neurons activity through T-type calcium channels

The functional role of CFTR in spermatogenesis

Differentiation of adult rat bone marrow stem cells into epithelial progenitor cells in culture

Activation of the epithelial Na<sup>+</sup> channel triggers prostaglandin E<sub>2</sub> release and production required for embryo implantation.

Involvement of cystic fibrosis transmembrane conductance regulator (CFTR) in the pathogenesis of hydrosalpinx induced by Chlamydia trachomatis infection.

Deficient human β-defensin 1 underlies male infertility associated with poor sperm motility and genital tract infection.

The Sperm Small RNA Transcriptome: Implications beyond Reproductive Disorder.

Glucose-induced electrical activities and insulin secretion in pancreatic islet β-cells are modulated by CFTR.

Defb19 regulates the migration of germ cell and is involved in male fertility.

Progenitor Cells Derived from Drain Waste Product of Open-Heart Surgery in Children.

Progenitor Cells Derived from Drain Waste Product of Open-Heart Surgery in Children.

Involvement of Cl<sup>−</sup>/HCO<sub>3</sub><sup>−</sup> exchanger SLC26A3 and SLC26A6 in preimplantation embryo cleavage.

Defective CFTR-Dependent CREB Activation Results in Impaired Spermatogenesis and Azoospermia.

Cryptorchidism-induced CFTR down-regulation results in disruption of testicular tight junctions through up-regulation of NF-κB/COX-2/PGE2.

CD147 regulates apoptosis in mouse spermatocytes but not spermatogonia.

The N501Y Mutation of SARS-CoV-2 Spike Protein Impairs Spindle Assembly in Mouse Oocytes.

Dedifferentiation-Reprogrammed Mesenchymal Stem Cells with Improved Therapeutic Potential.

CD147 is required for matrix metalloproteinases-2 production and germ cell migration during spermatogenesis.

Epigenetic regulation of CFTR during cancer development and implications in cancer treatment (1048.9).