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Chronic spindle assembly checkpoint activation causes myelosuppression and gastrointestinal atrophy.
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- EMBO Reports, 2024, v. 25, n. 6, p. 2743, doi. 10.1038/s44319-024-00160-3
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- Article
MDM2 amplification in rod-shaped chromosomes provides clues to early stages of circularized gene amplification in liposarcoma.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06307-1
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- Article
Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition.
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- EMBO Journal, 2024, v. 43, n. 5, p. 666, doi. 10.1038/s44318-024-00031-6
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- Article
Disruption of the TP53 locus in osteosarcoma leads to TP53 promoter gene fusions and restoration of parts of the TP53 signalling pathway.
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- Journal of Pathology, 2024, v. 262, n. 2, p. 147, doi. 10.1002/path.6219
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- Article
IFNγ protects motor neurons from oxidative stress via enhanced global protein synthesis in FUS‐associated amyotrophic lateral sclerosis.
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- Brain Pathology, 2024, v. 34, n. 1, p. 1, doi. 10.1111/bpa.13206
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- Article
Chromosomal Instability-Driven Cancer Progression: Interplay with the Tumour Microenvironment and Therapeutic Strategies.
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- Cells (2073-4409), 2023, v. 12, n. 23, p. 2712, doi. 10.3390/cells12232712
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- Article
Neurodegeneration-associated protein VAPB regulates proliferation in medulloblastoma.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-45319-5
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- Article
Chromosomal instability and inflammation: a catch-22 for cancer cells.
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- Chromosome Research, 2023, v. 31, n. 3, p. 1, doi. 10.1007/s10577-023-09730-y
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- Article
Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain.
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- Life Science Alliance, 2023, v. 6, n. 7, p. 1, doi. 10.26508/lsa.202201730
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- Article
Targeted assembly of ectopic kinetochores to induce chromosome‐specific segmental aneuploidies.
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- EMBO Journal, 2023, v. 42, n. 10, p. 1, doi. 10.15252/embj.2022111587
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- Article
A kinesin‐based approach for inducing chromosome‐specific mis‐segregation in human cells.
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- EMBO Journal, 2023, v. 42, n. 10, p. 1, doi. 10.15252/embj.2022111559
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- Article
Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37356-5
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- Article
Short-term molecular consequences of chromosome mis-segregation for genome stability.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37095-7
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- Article
Replication stress generates distinctive landscapes of DNA copy number alterations and chromosome scale losses.
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- Genome Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s13059-022-02781-0
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- Article
Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 17, p. 9852, doi. 10.3390/ijms23179852
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- Article
The impact of monosomies, trisomies and segmental aneuploidies on chromosomal stability.
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- PLoS ONE, 2022, v. 17, n. 7, p. 1, doi. 10.1371/journal.pone.0268579
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- Article
Rapid and efficient generation of antigen‐specific isogenic T cells from cryopreserved blood samples.
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- Immunology & Cell Biology, 2022, v. 100, n. 4, p. 285, doi. 10.1111/imcb.12538
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- Article
A synthetic lethal screen identifies HDAC4 as a potential target in MELK overexpressing cancers.
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- G3: Genes | Genomes | Genetics, 2021, v. 11, n. 12, p. 1, doi. 10.1093/g3journal/jkab335
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- Article
Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2021, v. 40, n. 1, p. 1, doi. 10.1186/s13046-021-02124-0
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- Article
Understanding How Genetic Mutations Collaborate with Genomic Instability in Cancer.
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- Cells (2073-4409), 2021, v. 10, n. 2, p. 342, doi. 10.3390/cells10020342
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- Article
Acute systemic loss of Mad2 leads to intestinal atrophy in adult mice.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80169-5
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- Article
Centrosome defects cause microcephaly by activating the 53BP1‐USP28‐TP53 mitotic surveillance pathway.
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- EMBO Journal, 2021, v. 40, n. 1, p. 1, doi. 10.15252/embj.2020106118
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- Article
PIDDosome‐induced p53‐dependent ploidy restriction facilitates hepatocarcinogenesis.
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- EMBO Reports, 2020, v. 21, n. 12, p. 1, doi. 10.15252/embr.202050893
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- Article
BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome.
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- 2020
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- Publication type:
- journal article
Loss of NF2 defines a genetic subgroup of non‐FOS‐rearranged osteoblastoma.
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- Journal of Pathology: Clinical Research, 2020, v. 6, n. 4, p. 231, doi. 10.1002/cjp2.172
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- Article
A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity.
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- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-14551-2
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- Article
BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome.
- Published in:
- 2020
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- Publication type:
- journal article
BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome.
- Published in:
- Journal of Clinical Investigation, 2020, v. 130, n. 1, p. 171, doi. 10.1172/JCI126863
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- Article
Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition‐mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2‐deficient cancer cells.
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- Molecular Oncology, 2019, v. 13, n. 11, p. 2422, doi. 10.1002/1878-0261.12573
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- Article
The cGAS Paradox: Contrasting Roles for cGAS-STING Pathway in Chromosomal Instability.
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- Cells (2073-4409), 2019, v. 8, n. 10, p. 1228, doi. 10.3390/cells8101228
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- Article
FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05258-6
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- Article
RNAi screening of subtracted transcriptomes reveals tumor suppression by taurine-activated GABA<sub>A</sub> receptors involved in volume regulation.
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- PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0196979
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- Article
CIN and Aneuploidy: Different Concepts, Different Consequences.
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- BioEssays, 2018, v. 40, n. 1, p. n/a, doi. 10.1002/bies.201700147
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- Article
Revisiting the chromosome separation checkpoint (retrospective on DOI 10.1002/bies.201400140).
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- BioEssays, 2017, v. 39, n. 7, p. n/a, doi. 10.1002/bies.201700084
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- Article
Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells.
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- Nature Communications, 2017, v. 8, n. 7, p. 15981, doi. 10.1038/ncomms15981
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- Article
Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma.
- Published in:
- eLife, 2017, p. 1, doi. 10.7554/eLife.20873
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- Article
Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies.
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- Genome Biology, 2016, v. 17, p. 1, doi. 10.1186/s13059-016-0971-7
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- Article
Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons.
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- Genome Biology, 2016, v. 17, p. 1, doi. 10.1186/s13059-016-0976-2
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- Article
How to count chromosomes in a cell: An overview of current and novel technologies.
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- BioEssays, 2015, v. 37, n. 5, p. 570, doi. 10.1002/bies.201400218
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- Article
Better check late than never: The chromosome segregation checkpoint.
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- BioEssays, 2015, v. 37, n. 3, p. 235, doi. 10.1002/bies.201400212
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- Article