Works by Florio, Tullio
Results: 112
ERK1/2 and p38 MAP kinases control prion protein fragment 90-231-induced astrocyte proliferation and microglia activation.
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- Glia, 2007, v. 55, n. 14, p. 1469, doi. 10.1002/glia.20559
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- Article
Cultured astrocyte proliferation induced by extracellular guanosine involves endogenous adenosine and is raised by the co-presence of microglia.
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- Glia, 2000, v. 29, n. 3, p. 202, doi. 10.1002/(SICI)1098-1136(20000201)29:3<202::AID-GLIA2>3.0.CO;2-C
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- Article
Repurposed Biguanide Drugs in Glioblastoma Exert Antiproliferative Effects via the Inhibition of Intracellular Chloride Channel 1 Activity.
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- Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00135
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- Article
Proteasome inhibitors in medullary thyroid carcinoma: time to restart with clinical trials?
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- Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1145926
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- Article
Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death.
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- Cell Death & Disease, 2018, v. 9, n. 2, p. 1, doi. 10.1038/s41419-017-0252-8
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- Article
Emerging Targets in Pituitary Adenomas: Role of the CXCL12/CXCR4-R7 System.
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- International Journal of Endocrinology, 2014, p. 1, doi. 10.1155/2014/753524
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- Article
Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors.
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- Frontiers in Cellular Neuroscience, 2017, p. 1, doi. 10.3389/fncel.2017.00312
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- Article
Inhibition of the Autophagy Pathway Synergistically Potentiates the Cytotoxic Activity of Givinostat (ITF2357) on Human Glioblastoma Cancer Stem Cells.
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- Frontiers in Molecular Neuroscience, 2016, v. 9, p. 1, doi. 10.3389/fnmol.2016.00107
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- Article
The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma.
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- Cell Cycle, 2015, v. 14, n. 21, p. 3418, doi. 10.1080/15384101.2015.1090063
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- Article
Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures.
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- Cell Cycle, 2013, v. 12, n. 3, p. 491, doi. 10.4161/cc.23372
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- Article
Metformin selectively affects human glioblastoma tumor-initiating cell viability.
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- Cell Cycle, 2013, v. 12, n. 1, p. 145, doi. 10.4161/cc.23050
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- Article
An Alu-like RNA promotes cell differentiation and reduces malignancy of human neuroblastoma cells.
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- FASEB Journal, 2010, v. 24, n. 10, p. 4033, doi. 10.1096/fj.10-157032
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- Article
Contribution of two conserved glycine residues to fibrillogenesis of the 106–126 prion protein fragment. Evidence that a soluble variant of the 106–126 peptide is neurotoxic.
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- Journal of Neurochemistry, 2003, v. 85, n. 1, p. 62, doi. 10.1046/j.1471-4159.2003.01664.x
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- Article
Glial and Neuronal Cells Express Functional Chemokine Receptor CXCR4 and Its Natural Ligand Stromal Cell-Derived Factor 1.
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- Journal of Neurochemistry, 1999, v. 73, n. 6, p. 2348, doi. 10.1046/j.1471-4159.1999.0732348.x
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- Article
β25-35 Alters Calcium Homeostasis and Induces Neurotoxicity in Cerebellar Granule Cells.
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- Journal of Neurochemistry, 1996, v. 66, n. 5, p. 1995, doi. 10.1046/j.1471-4159.1996.66051995.x
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- Article
Modulation by GTP of Basal and Agonist-Stimulated Striatal Adenylate Cyclase Activity Following Chronic Blockade of D<sub>1</sub> and D<sub>2</sub> Dopamine Receptors: Involvement of G Proteins in the Development of Receptor Supersensitivity.
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- Journal of Neurochemistry, 1992, v. 59, n. 5, p. 1667, doi. 10.1111/j.1471-4159.1992.tb10997.x
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- Article
In vivo and in vitro response to octreotide LAR in a TSH-secreting adenoma: characterization of somatostatin receptor expression and role of subtype 5.
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- Pituitary, 2011, v. 14, n. 2, p. 141, doi. 10.1007/s11102-010-0271-2
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- Article
Immune Checkpoint Blockade in Lung Carcinoids with Aggressive Behaviour: One More Arrow in Our Quiver?
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- Journal of Clinical Medicine, 2022, v. 11, n. 4, p. N.PAG, doi. 10.3390/jcm11041019
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- Article
Emerging Therapies in Pheochromocytoma and Paraganglioma: Immune Checkpoint Inhibitors in the Starting Blocks.
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- Journal of Clinical Medicine, 2021, v. 10, n. 1, p. 88, doi. 10.3390/jcm10010088
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- Article
MCM2 and Carbonic Anhydrase 9 Are Novel Potential Targets for Neuroblastoma Pharmacological Treatment.
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- Biomedicines, 2020, v. 8, n. 11, p. 471, doi. 10.3390/biomedicines8110471
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- Article
The rat tyrosine phosphatase?increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue.
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- Oncogene, 2005, v. 24, n. 19, p. 3187, doi. 10.1038/sj.onc.1208510
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- Article
CXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment.
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- Frontiers in Cellular Neuroscience, 2014, v. 8, p. 1, doi. 10.3389/fncel.2014.00144
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- Article
Protective Effects of Some Creatine Derivatives in Brain Tissue Anoxia.
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- Neurochemical Research, 2008, v. 33, n. 5, p. 765, doi. 10.1007/s11064-007-9492-9
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- Article
Interleukin-1 Modulation of Anterior Pituitary Function.
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- Annals of the New York Academy of Sciences, 1990, v. 594, n. 1, p. 489, doi. 10.1111/j.1749-6632.1990.tb40537.x
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- Article
Adiponectin as Novel Regulator of Cell Proliferation in Human Glioblastoma.
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- Journal of Cellular Physiology, 2014, v. 229, n. 10, p. 1444, doi. 10.1002/jcp.24582
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- Article
Different Molecular Mechanisms Mediate Direct or Glia-Dependent Prion Protein Fragment 90-231 Neurotoxic Effects in Cerebellar Granule Neurons.
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- Neurotoxicity Research, 2017, v. 32, n. 3, p. 381, doi. 10.1007/s12640-017-9749-2
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- Article
Excitotoxicity Through NMDA Receptors Mediates Cerebellar Granule Neuron Apoptosis Induced by Prion Protein 90-231 Fragment.
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- Neurotoxicity Research, 2013, v. 23, n. 4, p. 301, doi. 10.1007/s12640-012-9340-9
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- Article
Efficacy of Novel Acridine Derivatives in the Inhibition of hPrP90-231 Prion Protein Fragment Toxicity.
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- Neurotoxicity Research, 2011, v. 19, n. 4, p. 556, doi. 10.1007/s12640-010-9189-8
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- Article
Dual Modulation of ERK1/2 and p38 MAP Kinase Activities Induced by Minocycline Reverses the Neurotoxic Effects of the Prion Protein Fragment 90–231.
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- Neurotoxicity Research, 2009, v. 15, n. 2, p. 138, doi. 10.1007/s12640-009-9015-3
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- Article
Dual Modulation of ERK1/2 and p38 MAP Kinase Activities Induced by Minocycline Reverses the Neurotoxic Effects of the Prion Protein Fragment 90-231.
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- Neurotoxicity Research, 2009, v. 15, n. 1, p. 1
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- Article
Boron Vehiculating Nanosystems for Neutron Capture Therapy in Cancer Treatment.
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- Cells (2073-4409), 2022, v. 11, n. 24, p. 4029, doi. 10.3390/cells11244029
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Exosomes and Extracellular Vesicles as Emerging Theranostic Platforms in Cancer Research.
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- Cells (2073-4409), 2020, v. 9, n. 12, p. 2569, doi. 10.3390/cells9122569
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- Article
Emerging Role of Cellular Prion Protein in the Maintenance and Expansion of Glioma Stem Cells †.
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- Cells (2073-4409), 2019, v. 8, n. 11, p. 1458, doi. 10.3390/cells8111458
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- Article
Extracellular Vesicles Loaded miRNAs as Potential Modulators Shared Between Glioblastoma, and Parkinson's and Alzheimer's Diseases.
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- Frontiers in Cellular Neuroscience, 2020, v. 14, p. N.PAG, doi. 10.3389/fncel.2020.590034
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P.24: Addressing thermal and mechanical stability of human prion protein with single molecule and ensemble measurements.
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- Prion, 2014, v. 8, p. 35
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- Article
Modulating voltage-gated sodium channels to enhance differentiation and sensitize glioblastoma cells to chemotherapy.
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- Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-024-01819-z
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- Article
The expression of pro-prion, a transmembrane isoform of the prion protein, leads to the constitutive activation of the canonical Wnt/β-catenin pathway to sustain the stem-like phenotype of human glioblastoma cells.
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- Cancer Cell International, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12935-024-03581-1
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The Impact of Experimental Conditions on Cell Mechanics as Measured with Nanoindentation.
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- Nanomaterials (2079-4991), 2023, v. 13, n. 7, p. 1190, doi. 10.3390/nano13071190
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Cellular Mechanosensitivity: Validation of an Adaptable 3D-Printed Device for Microindentation.
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- Nanomaterials (2079-4991), 2022, v. 12, n. 15, p. 2691, doi. 10.3390/nano12152691
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- Article
Ruta graveolens L. Induces Death of Glioblastoma Cells and Neural Progenitors, but Not of Neurons, via ERK 1/2 and AKT Activation.
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- PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0118864
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P4-151: The intracellular accumulation of the recombinant PRP90-231 fragment is responsible for its cytotoxicity in vitro
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- 2006
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- Abstract
P1-422: FRET analysis of amyloid precursor protein, presenilin 1 and Grb2 interactions
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- 2006
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- Abstract
P1-420: Tyrosine 682 on amyloid precursor protein influences ERK1/2 signaling
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- 2006
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- Abstract
P4-151: The intracellular accumulation of the recombinant PRP90-231 fragment is responsible for its cytotoxicity in vitro
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- 2006
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- Abstract
P1-422: FRET analysis of amyloid precursor protein, presenilin 1 and Grb2 interactions
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- 2006
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- Abstract
P1-420: Tyrosine 682 on amyloid precursor protein influences ERK1/2 signaling
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- 2006
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- Abstract
Tryptophan hydroxylase 2 ( TPH2) in a neuronal cell line: modulation by cell differentiation and NRSF/rest activity.
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- Journal of Neurochemistry, 2012, v. 123, n. 6, p. 963, doi. 10.1111/jnc.12004
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Intracellular accumulation of a mild-denatured monomer of the human PrP fragment 90–231, as possible mechanism of its neurotoxic effects.
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- Journal of Neurochemistry, 2007, v. 103, n. 6, p. 2597, doi. 10.1111/j.1471-4159.2007.04965.x
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Different structural stability and toxicity of PrP<sup>ARR</sup> and PrP<sup>ARQ</sup> sheep prion protein variants.
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- Journal of Neurochemistry, 2007, v. 103, n. 6, p. 2291, doi. 10.1111/j.1471-4159.2007.04934.x
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In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors.
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- BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1235-8
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- Article