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MUC1 cell surface mucin is a critical element of the mucosal barrier to infection.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 8, p. 2313, doi. 10.1172/JCI26705
By:
- McAuley, Julie L.;
- Linden, Sara K.;
- Chin Wen Png;
- King, Rebecca M.;
- Pennington, Helen L.;
- Gendler, Sandra J.;
- Florin, Timothy H.;
- Hill, Geoff R.;
- Korolik, Victoria;
- McGuckin, Michael A.
Publication type:
Article
HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants.
Published in:
Nature Genetics, 2014, v. 46, n. 10, p. 1131, doi. 10.1038/ng.3093
By:
- Heap, Graham A;
- Bampton, Peter;
- Bell, Sally;
- Cole, Andy;
- Connor, Susan J;
- Creed, Tom;
- Cummings, Fraser R;
- D'Amato, Mauro;
- Fedorak, Richard N;
- Florin, Timothy H;
- Gaya, Daniel R;
- Weedon, Michael N;
- Greig, Emma;
- Halfvarson, Jonas;
- Hart, Alisa;
- Irving, Peter M;
- Jones, Gareth;
- Lees, Charlie;
- Satsangi, Jack;
- Karban, Amir
Publication type:
Article
High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22.
Published in:
Scientific Reports, 2016, p. 28990, doi. 10.1038/srep28990
By:
- Gulhane, Max;
- Murray, Lydia;
- Lourie, Rohan;
- Tong, Hui;
- Sheng, Yong H.;
- Wang, Ran;
- Kang, Alicia;
- Schreiber, Veronika;
- Wong, Kuan Yau;
- Magor, Graham;
- Denman, Stuart;
- Begun, Jakob;
- Florin, Timothy H.;
- Perkins, Andrew;
- Cuív, Páraic Ó.;
- McGuckin, Michael A.;
- Hasnain, Sumaira Z.
Publication type:
Article
Mucin Dynamics in Intestinal Bacterial Infection.
Published in:
PLoS ONE, 2008, v. 3, n. 12, p. 1, doi. 10.1371/journal.pone.0003952
By:
- Lindén, Sara K.;
- Florin, Timothy H. J.;
- McGuckin, Michael A.
Publication type:
Article
Gut inflammation and adaptive immunity amplify acetaminophen toxicity in bowel and liver.
Published in:
Journal of Gastroenterology & Hepatology, 2023, v. 38, n. 4, p. 609, doi. 10.1111/jgh.16102
By:
- Alabbas, Saleh Y;
- Giri, Rabina;
- Oancea, Iulia;
- Davies, Julie;
- Schreibner, Veronika;
- Florin, Timothy H;
- Begun, Jakob
Publication type:
Article
Oral bismuth for chronic intractable diarrheal conditions?
Published in:
Clinical & Experimental Gastroenterology, 2013, v. 6, p. 19, doi. 10.2147/CEG.S41743
By:
- Thazhath, Sony S.;
- Haque, Mazhar;
- Florin, Timothy H.
Publication type:
Article
Anti-tumour necrosis factor-alpha treatment for perianal Crohn's disease in Australia.
Published in:
2010
By:
- Burger DC;
- Lawrance IC;
- Bampton PA;
- Prosser R;
- Croft A;
- Gilshenan K;
- Radford-Smith GL;
- Florin TH;
- Burger, Daniel C;
- Lawrance, Ian C;
- Bampton, Peter A;
- Prosser, Ruth;
- Croft, Anthony;
- Gilshenan, Kristen;
- Radford-Smith, Graham L;
- Florin, Timothy H
Publication type:
journal article
Anti-tumour necrosis factor-α treatment for perianal Crohn's disease in Australia.
Published in:
Medical Journal of Australia, 2010, v. 192, n. 7, p. 375, doi. 10.5694/j.1326-5377.2010.tb03557.x
By:
- Burger, Daniel C.;
- Lawrance, Ian C.;
- Bampton, Peter A.;
- Prosser, Ruth;
- Croft, Anthony;
- Gilshenan, Kristen;
- Radford-Smith, Graham L.;
- Florin, Timothy H.
Publication type:
Article
Hepatosplenic T-cell lymphoma following infliximab therapy for Crohn's disease.
Published in:
2009
By:
- Burger, Daniel C.;
- Florin, Timothy H. J.
Publication type:
Letter
Tumour necrosis factor inhibitors.
Published in:
2005
By:
- Nash, Peter T;
- Florin, Timothy H J
Publication type:
journal article
Lessons from early large-scale adoption of celecoxib and rofecoxib by Australian general practitioners.
Published in:
2004
By:
- Florin, Timothy H J
Publication type:
commentary
MUC1 Limits Helicobacter pylori Infection both by Steric Hindrance and by Acting as a Releasable Decoy.
Published in:
PLoS Pathogens, 2009, v. 5, n. 10, p. 1, doi. 10.1371/journal.ppat.1000617
By:
- Lindén, Sara K.;
- Sheng, Yong H.;
- Every, Alison L.;
- Miles, Kim M.;
- Skoog, Emma C.;
- Florin, Timothy H. J.;
- Sutton, Philip;
- McGuckin, Michael A.
Publication type:
Article
Listeria monocytogenes internalins bind to the human intestinal mucin MUC2.
Published in:
Archives of Microbiology, 2008, v. 190, n. 1, p. 101, doi. 10.1007/s00203-008-0358-6
By:
- Lindén, Sara K.;
- Bierne, Hélène;
- Sabet, Christophe;
- Chin Wen Png;
- Florin, Timothy H.;
- McGuckin, Michael A.;
- Cossart, Pascale
Publication type:
Article
Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease.
Published in:
JAMA: Journal of the American Medical Association, 2019, v. 321, n. 8, p. 773, doi. 10.1001/jama.2019.0709
By:
- Walker, Gareth J.;
- Harrison, James W.;
- Heap, Graham A.;
- Voskuil, Michiel D.;
- Andersen, Vibeke;
- Anderson, Carl A.;
- Ananthakrishnan, Ashwin N.;
- Barrett, Jeffrey C.;
- Beaugerie, Laurent;
- Bewshea, Claire M.;
- Cole, Andy T.;
- Cummings, Fraser R.;
- Daly, Mark J.;
- Ellul, Pierre;
- Fedorak, Richard N.;
- Festen, Eleonora A. M.;
- Florin, Timothy H.;
- Gaya, Daniel R.;
- Halfvarson, Jonas;
- Hart, Ailsa L.
Publication type:
Article
Mucin dynamics and enteric pathogens.
Published in:
Nature Reviews Microbiology, 2011, v. 9, n. 4, p. 265, doi. 10.1038/nrmicro2538
By:
- McGuckin, Michael A.;
- Lindén, Sara K.;
- Sutton, Philip;
- Florin, Timothy H.
Publication type:
Article
Therapeutic Drug Monitoring for IBD Children on Thioguanine.
Published in:
2023
By:
- Florin, Timothy H.;
- Duley, John A.
Publication type:
Letter
A possible role for bile acid in the control of methanogenesis and the accumulation of hydrogen gas in the human colon.
Published in:
Journal of Gastroenterology & Hepatology, 1994, v. 9, n. 2, p. 112, doi. 10.1111/j.1440-1746.1994.tb01228.x
By:
- FLORIN, TIMOTHY H. J.;
- JABBAR, IBTISSAM A.
Publication type:
Article
Inosine Triphosphate Pyrophosphohydrolase (ITPA) polymorphic sequence variants in adult hematological malignancy patients and possible association with mitochondrial DNA defects.
Published in:
Journal of Hematology & Oncology, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-8722-6-24
By:
- Zamzami, Mazin A.;
- Duley, John A.;
- Price, Gareth R.;
- Venter, Deon J.;
- Yarham, John W.;
- Taylor, Robert W.;
- Catley, Laurence P.;
- Florin, Timothy H. J.;
- Marinaki, Anthony M.;
- Bowling, Francis
Publication type:
Article
An Extremes of Phenotype Approach Confirms Significant Genetic Heterogeneity in Patients with Ulcerative Colitis.
Published in:
Journal of Crohn's & Colitis, 2023, v. 17, n. 2, p. 277, doi. 10.1093/ecco-jcc/jjac121
By:
- Mortlock, Sally;
- Lord, Anton;
- Montgomery, Grant;
- Zakrzewski, Martha;
- Simms, Lisa A;
- Krishnaprasad, Krupa;
- Hanigan, Katherine;
- Doecke, James D;
- Walsh, Alissa;
- Lawrance, Ian C;
- Bampton, Peter A;
- Andrews, Jane M;
- Mahy, Gillian;
- Connor, Susan J;
- Sparrow, Miles P;
- Bell, Sally;
- Florin, Timothy H;
- Begun, Jakob;
- Gearry, Richard B;
- Radford-Smith, Graham L
Publication type:
Article
Anti-TNF Therapeutic Drug Monitoring in Postoperative Crohn's Disease.
Published in:
Journal of Crohn's & Colitis, 2018, v. 12, n. 6, p. 653, doi. 10.1093/ecco-jcc/jjy003
By:
- Wright, Emily K.;
- Kamm, Michael A.;
- De Cruz, Peter;
- Hamilton, Amy L.;
- Selvaraj, Fabiyola;
- Princen, Fred;
- Gorelik, Alexandra;
- Liew, Danny;
- Prideaux, Lani;
- Lawrance, Ian C.;
- Andrews, Jane M.;
- Bampton, Peter A.;
- Jakobovits, Simon L.;
- Florin, Timothy H.;
- Gibson, Peter R.;
- Debinski, Henry;
- Macrae, Finlay A.;
- Samuel, Douglas;
- Kronborg, Ian;
- Radford-Smith, Graham
Publication type:
Article
Effect of Intestinal Resection on Quality of Life in Crohn's Disease.
Published in:
Journal of Crohn's & Colitis, 2015, v. 9, n. 6, p. 452, doi. 10.1093/ecco-jcc/jjv058
By:
- Wright, Emily K.;
- Kamm, Michael A.;
- De Cruz, Peter;
- Hamilton, Amy L.;
- Ritchie, Kathryn J.;
- Krejany, Efrosinia O.;
- Gorelik, Alexandra;
- Liew, Danny;
- Prideaux, Lani;
- Lawrance, Ian C.;
- Andrews, Jane M.;
- Bampton, Peter A.;
- Sparrow, Miles P.;
- Florin, Timothy H.;
- Gibson, Peter R.;
- Debinski, Henry;
- Gearry, Richard B.;
- Macrae, Finlay A.;
- Leong, Rupert W.;
- Kronborg, Ian
Publication type:
Article
Aberrant Mucin Assembly in Mice Causes Endoplasmic Reticulum Stress and Spontaneous Inflammation Resembling Ulcerative Colitis.
Published in:
PLoS Medicine, 2008, v. 5, n. 3, p. e54, doi. 10.1371/journal.pmed.0050054
By:
- Heazlewood, Chad K.;
- Cook, Matthew C.;
- Eri, Rajaraman;
- Price, Gareth R.;
- Tauro, Sharyn B.;
- Taupin, Douglas;
- Thornton, David J.;
- Png, Chin Wen;
- Crockford, Tanya L.;
- Cornall, Richard J.;
- Adams, Rachel;
- Kato, Masato;
- Nelms, Keats A.;
- Hong, Nancy A.;
- Florin, Timothy H. J.;
- Goodnow, Christopher C.;
- McGuckin, Michael A.
Publication type:
Article
Serologic antibodies in relation to outcome in postoperative Crohn's disease.
Published in:
Journal of Gastroenterology & Hepatology, 2017, v. 32, n. 6, p. 1195, doi. 10.1111/jgh.13677
By:
- Hamilton, Amy L;
- Kamm, Michael A;
- De Cruz, Peter;
- Wright, Emily K;
- Selvaraj, Fabiyola;
- Princen, Fred;
- Gorelik, Alexandra;
- Liew, Danny;
- Lawrance, Ian C;
- Andrews, Jane M;
- Bampton, Peter A;
- Sparrow, Miles P;
- Florin, Timothy H;
- Gibson, Peter R;
- Debinski, Henry;
- Gearry, Richard B;
- Macrae, Finlay A;
- Leong, Rupert W;
- Kronborg, Ian;
- Radford ‐ Smith, Graham
Publication type:
Article
Smoking behaviour modifies IL23r-associated disease risk in patients with Crohn's disease.
Published in:
Journal of Gastroenterology & Hepatology, 2015, v. 30, n. 2, p. 299, doi. 10.1111/jgh.12674
By:
- Doecke, James D;
- Simms, Lisa A;
- Zhao, Zhen Zhen;
- Roberts, Rebecca L;
- Fowler, Elizabeth V;
- Croft, Anthony;
- Lin, Angela;
- Huang, Ning;
- Whiteman, David C;
- Florin, Timothy H J;
- Barclay, Murray L;
- Merriman, Tony R;
- Gearry, Richard B;
- Montgomery, Grant W;
- Radford‐Smith, Graham L
Publication type:
Article
Mucins in inflammatory bowel diseases and colorectal cancer.
Published in:
Journal of Gastroenterology & Hepatology, 2012, v. 27, n. 1, p. 28, doi. 10.1111/j.1440-1746.2011.06909.x
By:
- Sheng, Yong H;
- Hasnain, Sumaira Z;
- Florin, Timothy H J;
- McGuckin, Michael A
Publication type:
Article
Serious infections in patients with inflammatory bowel disease receiving anti-tumor-necrosis-factor-alpha therapy: An Australian and New Zealand experience IC Lawrance et al. Infections with anti-TNF-α in IBD.
Published in:
Journal of Gastroenterology & Hepatology, 2010, v. 25, n. 11, p. 1732, doi. 10.1111/j.1440-1746.2010.06407.x
By:
- Lawrance, Ian C.;
- Radford-Smith, Graham L.;
- Bampton, Peter A.;
- Andrews, Jane M.;
- Tan, Pok-Kern;
- Croft, Anthony;
- Gearry, Richard B.;
- Florin, Timothy H. J.
Publication type:
Article
Azathioprine: When less is more.
Published in:
2008
By:
- Duley, John A.;
- Florin, Timothy H. J.
Publication type:
Editorial
Relationship between disease severity, quality of life and health-care resource use in a cross-section of Australian patients with Crohn's disease.
Published in:
Journal of Gastroenterology & Hepatology, 2007, v. 22, n. 8, p. 1306, doi. 10.1111/j.1440-1746.2007.04930.x
By:
- Gibson, Peter R.;
- Weston, Adèle R.;
- Shann, Amelia;
- Florin, Timothy H. J.;
- Lawrance, Ian C.;
- Macrae, Finlay A.;
- Radford-Smith, Graham
Publication type:
Article
Mucolytic Bacteria With Increased Prevalence in IBD Mucosa Augment In Vitro Utilization of Mucin by Other Bacteria.
Published in:
American Journal of Gastroenterology (Springer Nature), 2010, v. 105, n. 11, p. 2420, doi. 10.1038/ajg.2010.281
By:
- Chin Wen Png;
- Lindén, Sara K.;
- Gilshenan, Kristen S.;
- Zoetendal, Erwin G.;
- McSweeney, Chris S.;
- Sly, Lindsay I.;
- McGuckin, Michael A.;
- Florin, Timothy H. J.
Publication type:
Article
KCNN4 Gene Variant Is Associated With Ileal Crohn's Disease in the Australian and New Zealand Population.
Published in:
American Journal of Gastroenterology (Springer Nature), 2010, v. 105, n. 10, p. 2209, doi. 10.1038/ajg.2010.161
By:
- Simms, Lisa A.;
- Doecke, James D.;
- Roberts, Rebecca L.;
- Fowler, Elizabeth V.;
- Zhen Zhen Zhao;
- McGuckin, Michael A.;
- Ning Huang;
- Hayward, Nicholas K.;
- Webb, Penelope M.;
- Whiteman, David C.;
- Cavanaugh, Juleen A.;
- McCallum, Ruth;
- Florin, Timothy H. J.;
- Barclay, Murray L.;
- Gearry, Richard B.;
- Merriman, Tony R.;
- Montgomery, Grant W.;
- Radford-Smith, Graham L.
Publication type:
Article
ATG16L1 T300A Shows Strong Associations With Disease Subgroups in a Large Australian IBD Population: Further Support for Significant Disease Heterogeneity.
Published in:
American Journal of Gastroenterology (Springer Nature), 2008, v. 103, n. 10, p. 2519, doi. 10.1111/j.1572-0241.2008.02023.x
By:
- Fowler, Elizabeth V.;
- Doecke, James;
- Simms, Lisa A.;
- Zhen Zhen Zhao;
- Webb, Penelope M.;
- Hayward, Nicholas K.;
- Whiteman, David C.;
- Florin, Timothy H.;
- Montgomery, Grant W.;
- Cavanaugh, Juleen A.;
- Radford-Smith, Graham L.
Publication type:
Article
CD40 and CD86 Upregulation With Divergent CMRF44 Expression on Blood Dendritic Cells in Inflammatory Bowel Diseases.
Published in:
American Journal of Gastroenterology (Springer Nature), 2001, v. 96, n. 10, p. 2946, doi. 10.1111/j.1572-0241.2001.04686.x
By:
- Vuckovic, Slavica;
- Florin, Timothy H. J.;
- Khalil, Dalia;
- Zhang, Min F.;
- Patel, Kalpana;
- Hamilton, Iona;
- Hart, Derek N. J.
Publication type:
Article
Shared and Unique Environmental Factors Determine the Ecology of Methanogens in Humans and Rats.
Published in:
American Journal of Gastroenterology (Springer Nature), 2000, v. 95, n. 10, p. 2872, doi. 10.1111/j.1572-0241.2000.02319.x
By:
- Florin, Timothy H. J.;
- Gu Zhu;
- Kirk, Katherine M.;
- Martin, Nicholas G.
Publication type:
Article

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