Works matching AU Flockhart, D.A.

Results: 15

Clinical significance of the cytochrome P450 2C19 genetic polymorphism.

Published in:

2002

By:

Desta, Z.;
Zhao, X.;
Shin, J-G.;
Flockhart, D.A.;
Desta, Zeruesenay;
Zhao, Xiaojiong;
Shin, Jae-Gook;
Flockhart, David A

Publication type:

journal article

Pharmacogenetic Predictors of Tamoxifen Effect on Bone Mineral Density.

Published in:

Clinical Pharmacology & Therapeutics, 2003, v. 73, n. 2, p. P42, doi. 10.1016/S0009-9236(03)90513-3

By:

Rehman, M.I.;
Lee, K.;
Skaar, T.;
Arefayene, M.;
Stearns, V.;
Flockhart, D.A.

Publication type:

Article

Correlation of pharmacogenetic genotype with steady-state metabolic profiles of tamoxifen: effect on active metabolite concentrations.

Published in:

Clinical Pharmacology & Therapeutics, 2003, v. 73, n. 2, p. P55, doi. 10.1016/S0009-9236(03)90561-3

By:

Lee, K.;
Desta, Z.;
Steans, V.;
Hayes, D.F.;
Jones, D.R.;
Flockhart, D.A.

Publication type:

Article

Atypical kinetics of CYP2B6-catalyzed reactions: Evidence for separate binding sites within the active site.

Published in:

Clinical Pharmacology & Therapeutics, 2003, v. 73, n. 2, p. P7, doi. 10.1016/S0009-9236(03)90380-8

By:

Desta, Z.;
Ward, B.A.;
Flockhart, D.A.

Publication type:

Article

Efavirenz is a specific phenotyping tool for cytochrome P450 2B6: Implications for HIV therapy.

Published in:

Clinical Pharmacology & Therapeutics, 2003, v. 73, n. 2, p. P7, doi. 10.1016/S0009-9236(03)90381-X

By:

Desta, Z.;
Ward, B.A.;
Hall, S.D.;
Flockhart, D.A.

Publication type:

Article

Haloperidol metabolites inhibit CYP2D6 catalyzed dextromethorphan O-demethylation in vitro.

Published in:

Clinical Pharmacology & Therapeutics, 1999, v. 65, n. 2, p. 143, doi. 10.1016/S0009-9236(99)80103-9

By:

Shin, J.G.;
Kane, K.;
Flockhart, D.A.

Publication type:

Article

Reduced CYP2C19 Activity in Cancer Patients.

Published in:

Clinical Pharmacology & Therapeutics, 1999, v. 65, n. 2, p. 196, doi. 10.1016/S0009-9236(99)80312-9

By:

Williams, M.L.;
Bhargava, P.;
Marshall, J.L.;
Flockhart, D.A.;
Wainer, I.W.

Publication type:

Article

Metabolism of An Anabolic Androgenic Steroid Oxymetholone by Human Cytochrome P450s.

Published in:

Clinical Pharmacology & Therapeutics, 1999, v. 65, n. 2, p. 136, doi. 10.1016/S0009-9236(99)80075-7

By:

Thacker, D.L.;
Wainer, I.;
Lerch, C.;
Fried, K.;
Flockhart, D.A.

Publication type:

Article

In vitro metabolism and interaction of cilostazol with human hepatic cytochrome P450 isoforms.

Published in:

Human & Experimental Toxicology, 2000, v. 19, n. 3, p. 178, doi. 10.1191/096032700678827717

By:

Abbas, R.;
Chow, C.P.;
Browder, N.J.;
Thacker, D.;
Bramer, S.L.;
Fu, C.J.;
Forbes, W.;
Odomi, M.;
Flockhart, D.A.

Publication type:

Article

Influence of Gender on Quinidine (Q) Pharmacokinetics (PK).

Published in:

Clinical Pharmacology & Therapeutics, 1996, v. 59, n. 2, p. 188, doi. 10.1038/sj.clpt.1996.253

By:

Benton, R.E.;
Flockhart, D.A.;
Sale, M.;
Woosley, R.L.

Publication type:

Article

RR-QT Relationships Differ During Exercise- and Isoproterenol-Induced Tachycardia: Effect of Beta-Blockade.

Published in:

Clinical Pharmacology & Therapeutics, 1996, v. 59, n. 2, p. 189, doi. 10.1038/sj.clpt.1996.254

By:

Drici, M.D.;
Sale, M.;
Burnett, A.;
Woosley, R.L.;
Flockhart, D.A.

Publication type:

Article

A Metabolic Interaction Between Clarithromycin and Pimozide May Result in Cardiac Toxicity.

Published in:

Clinical Pharmacology & Therapeutics, 1996, v. 59, n. 2, p. 189, doi. 10.1038/sj.clpt.1996.256

By:

Flockhart, D.A.;
Richard, E.;
Woosley, R.L.;
Pearle, P.L.;
Drici, M.D.

Publication type:

Article

Omeprazole (OPZ) as a Probe for the CYP2C19 Polymorphism in an African-American (AA) Population.

Published in:

Clinical Pharmacology & Therapeutics, 1996, v. 59, n. 2, p. 134, doi. 10.1038/sj.clpt.1996.34

By:

Marinac, J.S.;
Flockhart, D.A.;
Foxworth, J.W.;
Willsie Do, S.K.;
Daus, J.C.;
Balian, J.D.

Publication type:

Article

Utility of the Acid-Labile Metabolite (ALM) of Mephenytoin (MP) as a Probe for the CYP2C19 Metabolic Polymorphism.

Published in:

Clinical Pharmacology & Therapeutics, 1996, v. 59, n. 2, p. 135, doi. 10.1038/sj.clpt.1996.41

By:

Balian, J.D.;
Flockhart, D.A.;
Harns, J.W.

Publication type:

Article

A Rapid Method for Simultaneous Genotyping of CYP2D6 A and B Alleles Using the Polymerase Chain Reaction.

Published in:

Clinical Pharmacology & Therapeutics, 1996, v. 59, n. 2, p. 136, doi. 10.1038/sj.clpt.1996.45

By:

Owen, R.;
MacPherson, A.;
Flockhart, D.A.

Publication type:

Article