Works by Flint Beal, M.

Results: 216

Metabolomic profiling to develop blood biomarkers for Parkinson's disease.
Published in:
2008
By:
- Bogdanov M;
- Matson WR;
- Wang L;
- Matson T;
- Saunders-Pullman R;
- Bressman SS;
- Flint Beal M;
- Bogdanov, Mikhail;
- Matson, Wayne R;
- Wang, Lei;
- Matson, Theodore;
- Saunders-Pullman, Rachel;
- Bressman, Susan S;
- Flint Beal, M
Publication type:
journal article
Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid.
Published in:
Nature, 1986, v. 321, n. 6066, p. 168, doi. 10.1038/321168a0
By:
- Beal, M. Flint;
- Kowall, Neil W.;
- Ellison, David W.;
- Mazurek, Michael F.;
- Swartz, Kenton J.;
- Martin, Joseph B.
Publication type:
Article
Mitochondrial dysfunction and oxidative stress in induced pluripotent stem cell models of Parkinson's disease.
Published in:
European Journal of Neuroscience, 2019, v. 49, n. 4, p. 525, doi. 10.1111/ejn.14264
By:
- Bose, Anindita;
- Beal, M. Flint
Publication type:
Article
Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice.
Published in:
Nature Biotechnology, 2003, v. 21, n. 10, p. 1200, doi. 10.1038/nbt870
By:
- Barberi, Tiziano;
- Klivenyi, Peter;
- Calingasan, Noel Y.;
- Hyojin Lee, Noel Y.;
- Kawamata, Hibiki;
- Loonam, Kathleen;
- Perrier, Anselme L.;
- Bruses, Juan;
- Rubio, Maria E.;
- Topf, Norbert;
- Tabar, Viviane;
- Harrison, Neil L.;
- Beal, M. Flint;
- Moore, Malcolm A.S.;
- Studer, Lorenz
Publication type:
Article
Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease.
Published in:
Journal of Neuroscience, 2016, v. 36, n. 23, p. 6332, doi. 10.1523/JNEUROSCI.0426-16.2016
By:
- Ahuja, Manuj;
- Kaidery, Navneet Ammal;
- Lichuan Yang;
- Calingasan, Noel;
- Smirnova, Natalya;
- Gaisin, Arsen;
- Gaisina, Irina N.;
- Gazaryan, Irina;
- Hushpulian, Dmitry M.;
- Kaddour-Djebbar, Ismail;
- Bollag, Wendy B.;
- Morgan, John C.;
- Ratan, Rajiv R.;
- Starkov, Anatoly A.;
- Beal, M. Flint;
- Thomas, Bobby
Publication type:
Article
Behavioral deficits and progressive neuropathology in progranulin‐deficient mice: a mouse model of frontotemporal dementia.
Published in:
FASEB Journal, 2010, v. 24, n. 12, p. 4639, doi. 10.1096/fj.10.161471
By:
- Yin, Fangfang;
- Dumont, Magali;
- Banerjee, Rebecca;
- Ma, Yao;
- Li, Huihong;
- Lin, Michael T.;
- Beal, M. Flint;
- Nathan., Carl;
- Thomas, Bobby;
- Ding, Aihao
Publication type:
Article
Behavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementia.
Published in:
FASEB Journal, 2010, v. 24, n. 12, p. 4639, doi. 10.1096/fj.10-161471
By:
- Yin, Fangfang;
- Dumont, Magali;
- Banerjee, Rebecca;
- Ma, Yao;
- Huihong Li;
- Lin, Michael T.;
- Beal, M. Flint;
- Nathan, Carl;
- Thomas, Bobby;
- Ding, Aihao
Publication type:
Article
Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease.
Published in:
FASEB Journal, 2009, v. 23, n. 8, p. 2459, doi. 10.1096/fj.09-132928
By:
- Dumont, Magali;
- Willie, Elizabeth;
- Stack, Cliona;
- Calingasan, Noel Y.;
- Beal, M. Flint;
- Lin, Michael T.
Publication type:
Article
A pivotal role of matrix metalloproteinase-3 activity in dopaminergic neuronal degeneration via microglial activation.
Published in:
FASEB Journal, 2007, v. 21, n. 1, p. 179, doi. 10.1096/fj.06-5865com
By:
- Yoon Seong Kim;
- Dong Hee Choi;
- Block, Michelle L.;
- Lorenzl, Stefan;
- Lichuan Yang;
- Youn Jung Kim;
- Shuei Sugama;
- Byung Pil Cho;
- Onyou Hwang;
- Browne, Susan E.;
- Soo Yul Kim;
- Jau-Shyong Hong;
- Beal, M. Flint;
- Joh, Tong H.
Publication type:
Article
The role of mitochondria in inherited neurodegenerative diseases.
Published in:
Journal of Neurochemistry, 2006, v. 97, n. 6, p. 1659, doi. 10.1111/j.1471-4159.2006.03990.x
By:
- Kwong, Jennifer Q.;
- Beal, M. Flint;
- Manfredi, Giovanni
Publication type:
Article
Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn-superoxide dismutase mutant mice.
Published in:
Journal of Neurochemistry, 2006, v. 96, n. 5, p. 1349, doi. 10.1111/j.1471-4159.2006.03619.x
By:
- Damiano, Maria;
- Starkov, Anatoly A.;
- Petri, Susanne;
- Kipiani, Kathuna;
- Kiaei, Mahmoud;
- Mattiazzi, Marina;
- Flint Beal, M.;
- Manfredi, Giovanni
Publication type:
Article
Effects of CAG repeat length, HTT protein length and protein context on cerebral metabolism measured using magnetic resonance spectroscopy in transgenic mouse models of Huntington's disease.
Published in:
Journal of Neurochemistry, 2005, v. 95, n. 2, p. 553, doi. 10.1111/j.1471-4159.2005.03411.x
By:
- Jenkins, Bruce G.;
- Andreassen, Ole A.;
- Dedeoglu, Alpaslan;
- Leavitt, Blair;
- Hayden, Michael;
- Borchelt, David;
- Ross, Christopher A.;
- Ferrante, Robert J.;
- Beal, M. Flint
Publication type:
Article
Celastrol protects against MPTP- and 3-nitropropionic acid-induced neurotoxicity.
Published in:
Journal of Neurochemistry, 2005, v. 94, n. 4, p. 995, doi. 10.1111/j.1471-4159.2005.03253.x
By:
- Cleren, Carine;
- Calingasan, Noel Y.;
- Chen, Junya;
- Beal, M. Flint
Publication type:
Article
Neurotoxicity and behavioral deficits associated with.
Published in:
Journal of Neurochemistry, 2005, v. 94, n. 4, p. 1040, doi. 10.1111/j.1471-4159.2005.03257.x
By:
- Son, Jin H.;
- Kawamata, Hibiki;
- Yoo, Myung S.;
- Kim, Dae J.;
- Lee, Young K.;
- SooYoul Kim;
- Dawson, Ted M.;
- Hui Zhang;
- Sulzer, David;
- Lichuan Yang;
- Beal, M. Flint;
- DeGiorgio, Lorraine A.;
- Chun, Hong S.;
- Baker, Harriet;
- Chu Peng
Publication type:
Article
Integrative role of cPLA2 with COX-2 and the effect of non-steriodal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis.
Published in:
Journal of Neurochemistry, 2005, v. 93, n. 2, p. 403, doi. 10.1111/j.1471-4159.2005.03024.x
By:
- Kiaei, Mahmoud;
- Kipiani, Khatuna;
- Petri, Susanne;
- Dong-Kug Choi;
- Junyu Chen;
- Calingasan, Noel Y.;
- Beal, M. Flint
Publication type:
Article
3-Nitropropionic acid-induced neurotoxicity – assessed by ultra high resolution positron emission tomography with comparison to magnetic resonance spectroscopy.
Published in:
Journal of Neurochemistry, 2004, v. 89, n. 5, p. 1206, doi. 10.1111/j.1471-4159.2004.02408.x
By:
- Brownell, Anna-Liisa;
- Chen, Y. Iris;
- Yu, Meixiang;
- Wang, Xukui;
- Dedeoglu, Alpaslan;
- Cicchetti, Francesca;
- Jenkins, Bruce G.;
- Beal, M. Flint
Publication type:
Article
Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice.
Published in:
Journal of Neurochemistry, 2004, v. 89, n. 5, p. 1308, doi. 10.1111/j.1471-4159.2004.02455.x
By:
- Li, Feng;
- Calingasan, Noel Y.;
- Yu, Fangmin;
- Mauck, William M.;
- Toidze, Marine;
- Almeida, Claudia G.;
- Takahashi, Reisuke H.;
- Carlson, George A.;
- Beal, M. Flint;
- Lin, Michael T.;
- Gouras, Gunnar K.
Publication type:
Article
Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity.
Published in:
Journal of Neurochemistry, 2004, v. 88, n. 6, p. 1352, doi. 10.1046/j.1471-4159.2003.02263.x
By:
- Klivenyi, Peter;
- Starkov, Anatoly A.;
- Calingasan, Noel Y.;
- Gardian, Gabrielle;
- Browne, Susan E.;
- Lichuan Yang, Susan E.;
- Bubber, Parvesh;
- Gibson, Gary E.;
- Patel, Mulchand S.;
- Beal, M. Flint
Publication type:
Article
Increased survival and neuroprotective effects of BN82451 in a transgenic mouse model of Huntington's disease.
Published in:
2003
By:
- Klivenyi, Peter;
- Ferrante, Robert J.;
- Gardian, Gabrielle;
- Browne, Susan;
- Chabriert, Pierre-Etienne;
- Flint Beal, M.
Publication type:
Correction Notice
Increased survival and neuroprotective effects of BN82451 in a transgenic mouse model of Huntington's disease.
Published in:
Journal of Neurochemistry, 2003, v. 86, n. 1, p. 267, doi. 10.1046/j.1471-4159.2003.01868.x
By:
- Klivenyi, Peter;
- Ferrante, Robert J.;
- Gardian, Gabrielle;
- Browne, Susan;
- Chabrier, Pierre-Etienne;
- Beal, M. Flint
Publication type:
Article
Creatine therapy provides neuroprotection after onset of clinical symptoms in Huntington's disease transgenic mice.
Published in:
Journal of Neurochemistry, 2003, v. 85, n. 6, p. 1359, doi. 10.1046/j.1471-4159.2003.01706.x
By:
- Dedeoglu, Alpaslan;
- Kubilus, James K.;
- Yang, Lichuan;
- Ferrante, Kimberly L.;
- Hersch, Steven M.;
- Beal, M. Flint;
- Ferrante, and Robert J.
Publication type:
Article
Iron porphyrin treatment extends survival in a transgenic animal model of amyotrophic lateral sclerosis.
Published in:
Journal of Neurochemistry, 2003, v. 85, n. 1, p. 142, doi. 10.1046/j.1471-4159.2003.01639.x
By:
- Wu, Annie S.;
- Kiaei, Mahmoud;
- Aguirre, Norberto;
- Crow, John P.;
- Calingasan, Noel Y.;
- Browne, Susan E.;
- Beal, M. Flint
Publication type:
Article
Opening Lecture.
Published in:
Journal of Neurochemistry, 2001, v. 77, p. iv
By:
- Beal, M. Flint
Publication type:
Article
Increases in cortical glutamate concentrations in transgenic amyotropic lateral sclerosis mice....
Published in:
Journal of Neurochemistry, 2001, v. 77, n. 2, p. 383, doi. 10.1046/j.1471-4159.2001.00188.x
By:
- Andreassen, Ole A.;
- Jenkins, Bruce G.;
- Dedeoglu, Alpaslan;
- Ferrante, Kimberly L.;
- Bogdanov, Mikhail B.;
- Kaddurah-Daouk, Rima;
- Beal, M. Flint
Publication type:
Article
Malonate and 3-Nitropropionic Acid Neurotoxicity Are Reduced in Transgenic Mice Expressing a Caspase-1 Dominant-Negative Mutant.
Published in:
Journal of Neurochemistry, 2000, v. 75, n. 2, p. 847, doi. 10.1046/j.1471-4159.2000.0750847.x
By:
- Andreassen, Ole A;
- Ferrante, Robert J;
- Hughes, Duncan B;
- Klivenyi, Peter;
- Dedeoglu, Alpaslan;
- Ona, Victor O;
- Friedlander, Robert M;
- Beal, M Flint
Publication type:
Article
Nonlinear Decrease over Time in N-Acetyl Aspartate Levels in the Absence of Neuronal Loss and Increases in Glutamine and Glucose in Transgenic Huntington's Disease Mice.
Published in:
Journal of Neurochemistry, 2000, v. 74, n. 5, p. 2108, doi. 10.1046/j.1471-4159.2000.0742108.x
By:
- Jenkins, Bruce G.;
- Klivenyi, Peter;
- Kustermann, Ekkenhard;
- Andreassen, Ole A.;
- Ferrante, Robert J.;
- Rosen, Bruce R.;
- Beal, M. Flint
Publication type:
Article
Frontal Lobe Dysfunction in Progressive Supranuclear Palsy.
Published in:
Journal of Neurochemistry, 2000, v. 74, n. 2, p. 878, doi. 10.1046/j.1471-4159.2000.740878.x
By:
- Albers, David S.;
- Augood, Sarah J.;
- Park, Larry C. H.;
- Browne, Susan E.;
- Martin, Debroah M.;
- Adamson, Jennifer;
- Hutton, Michael;
- Standaert, David G.;
- Vonsattel, Jean Paul G.;
- Gibson, Gary E.;
- Beal, M. Flint
Publication type:
Article
Evidence for Oxidative Stress in the Subthalamic Nucleus in Progressive Supranuclear Palsy.
Published in:
Journal of Neurochemistry, 1999, v. 73, n. 2, p. 881, doi. 10.1046/j.1471-4159.1999.0730881.x
By:
- Albers, David S.;
- Augood, Sarah J.;
- Martin, Deborach M.;
- Standaert, David G.;
- Vonsattel, Jean Paul G.;
- Beal, M. Flint
Publication type:
Article
Mice Deficient in Group IV Cytosolic Phospholipase A2 Are Resistant to MPTP Neurotoxicity.
Published in:
Journal of Neurochemistry, 1998, v. 71, n. 6, p. 2634, doi. 10.1046/j.1471-4159.1998.71062634.x
By:
- Klivenyi, Peter;
- Beal, M. Flint;
- Ferrante, Robert J.;
- Andreassen, Ole A.;
- Wermer, Marieke;
- Chin, Mi-Reyoung;
- Bonventre, Joseph V.
Publication type:
Article
Increased Vulnerability to 3-Nitropropionic Acid in an Animal Model of Huntington's Disease.
Published in:
Journal of Neurochemistry, 1998, v. 71, n. 6, p. 2642, doi. 10.1046/j.1471-4159.1998.71062642.x
By:
- Bogdanov, Mikhail B.;
- Ferrante, Robert J.;
- Kuemmerle, Stefan;
- Klivenyi, Peter;
- Beal, M. Flint
Publication type:
Article
Elevated 'Hydroxyl Radical' Generation In Vivo in an Animal Model of Amyotrophic Lateral Sclerosis.
Published in:
Journal of Neurochemistry, 1998, v. 71, n. 3, p. 1321, doi. 10.1046/j.1471-4159.1998.71031321.x
By:
- Bogdanov, Mikhail B.;
- Ramos, Louis E.;
- Xu, Zuoshang;
- Beal, M. Flint
Publication type:
Article
Metabolic Dysfunction in Familial, but Not Sporadic, Amyotrophic Lateral Sclerosis.
Published in:
Journal of Neurochemistry, 1998, v. 71, n. 1, p. 281, doi. 10.1046/j.1471-4159.1998.71010281.x
By:
- Browne, Susan E.;
- Bowling, Allen C.;
- Baik, M. Jay;
- Gurney, Mark;
- Brown, Robert H.;
- Beal, M. Flint
Publication type:
Article
Iodoacetate Produces Striatal Excitotoxic Lesions.
Published in:
Journal of Neurochemistry, 1997, v. 69, n. 1, p. 285, doi. 10.1046/j.1471-4159.1997.69010285.x
By:
- Matthews, Russell T.;
- Ferrante, Robert J.;
- Jenkins, Bruce G.;
- Browne, Susan E.;
- Goetz, Katrine;
- Berger, Stephanie;
- Chen, Iris Y.-C.;
- Beal, M. Flint
Publication type:
Article
Striatal Malonate Lesions Are Attenuated in Neuronal Nitric Oxide Synthase Knockout Mice.
Published in:
Journal of Neurochemistry, 1996, v. 67, n. 1, p. 430, doi. 10.1046/j.1471-4159.1996.67010430.x
By:
- Schulz, Jörg B.;
- Huang, Paul L.;
- Matthews, Russell T.;
- Passov, David;
- Fishman, Mark C.;
- Beal, M. Flint
Publication type:
Article
3-Nitropropionic Acid Neurotoxicity Is Attenuated in Copper/Zinc Superoxide Dismutase Transgenic Mice.
Published in:
Journal of Neurochemistry, 1995, v. 65, n. 2, p. 919, doi. 10.1046/j.1471-4159.1995.65020919.x
By:
- Beal, M. Flint;
- Ferrante, Robert J.;
- Henshaw, Ross;
- Matthews, Russell T.;
- Chan, Pak H.;
- Kowall, Neil W.;
- Epstein, Charles J.;
- Schulz, Jörg B.
Publication type:
Article
Involvement of Free Radicals in Excitotoxicity In Vivo.
Published in:
Journal of Neurochemistry, 1995, v. 64, n. 5, p. 2239, doi. 10.1046/j.1471-4159.1995.64052239.x
By:
- Schulz, Jörg B.;
- Henshaw, D. Ross;
- Siwek, Donald;
- Jenkins, Bruce G.;
- Ferrante, Robert J.;
- Cipolloni, P. Ben;
- Kowall, Neil W.;
- Rosen, Bruce R.;
- Beal, M. Flint
Publication type:
Article
Superoxide Dismutase Concentration and Activity in Familial Amyotrophic Lateral Sclerosis.
Published in:
Journal of Neurochemistry, 1995, v. 64, n. 5, p. 2366, doi. 10.1046/j.1471-4159.1995.64052366.x
By:
- Bowling, Allen C.;
- Barkowski, Elizabeth E.;
- McKenna-Yasek, D.;
- Sapp, Peter;
- Horvitz, H. Robert;
- Beal, M. Flint;
- Brown, Robert H.
Publication type:
Article
Inhibition of Neuronal Nitric Oxide Synthase by 7-Nitroindazole Protects Against MPTP-Induced Neurotoxicity in Mice.
Published in:
Journal of Neurochemistry, 1995, v. 64, n. 2, p. 936, doi. 10.1046/j.1471-4159.1995.64020936.x
By:
- Schulz, Jörg B.;
- Matthews, Russell T.;
- Muqit, Miratul M. K.;
- Browne, Susan E.;
- Beal, M. Flint
Publication type:
Article
Cortical Cytochrome Oxidase Activity Is Reduced in Alzheimer's Disease.
Published in:
Journal of Neurochemistry, 1994, v. 63, n. 6, p. 2179, doi. 10.1046/j.1471-4159.1994.63062179.x
By:
- Mutisya, Elizabeth M.;
- Bowling, Allen C.;
- Beal, M. Flint
Publication type:
Article
Superoxide Dismutase Activity, Oxidative Damage, and Mitochondrial Energy Metabolism in Familial and Sporadic Amyotrophic Lateral Sclerosis.
Published in:
Journal of Neurochemistry, 1993, v. 61, n. 6, p. 2322, doi. 10.1111/j.1471-4159.1993.tb07478.x
By:
- Bowling, Allen C.;
- Schulz, Jorg B.;
- Brown, Robert H.;
- Beal, M. Flint
Publication type:
Article
Age-Dependent Striatal Excitotoxic Lesions Produced by the Endogenous Mitochondrial Inhibitor Malonate.
Published in:
Journal of Neurochemistry, 1993, v. 61, n. 3, p. 1147, doi. 10.1111/j.1471-4159.1993.tb03633.x
By:
- Beal, M. Flint;
- Brouillet, Emmanuel;
- Jenkins, Bruce;
- Henshaw, Ross;
- Rosen, Bruce;
- Hyman, Bradley T.
Publication type:
Article
Age-Dependent Vulnerability of the Striatum to the Mitochondrial Toxin 3-Nitropropionic Acid.
Published in:
Journal of Neurochemistry, 1993, v. 60, n. 1, p. 356, doi. 10.1111/j.1471-4159.1993.tb05859.x
By:
- Brouillet, Emmanuel;
- Jenkins, Bruce G.;
- Hyman, Bradley T.;
- Ferrante, Robert J.;
- Kowall, Neil W.;
- Srivastava, Rachana;
- Roy, Deborah Samanta;
- Rosen, Bruce R.;
- Beal, M. Flint
Publication type:
Article
1-Methyl-4-Phenylpyridinium Produces Excitotoxic Lesions in Rat Striatum as a Result of Impairment of Oxidative Metabolism.
Published in:
Journal of Neurochemistry, 1992, v. 58, n. 5, p. 1975, doi. 10.1111/j.1471-4159.1992.tb10080.x
By:
- Storey, Elsdon;
- Hyman, Bradley T.;
- Jenkins, Bruce;
- Brouillet, Emmanuel;
- Miller, Joanne M.;
- Rosen, Bruce R.;
- Beal, M. Flint
Publication type:
Article
Aminooxyacetic Acid Results in Excitotoxin Lesions by a Novel Indirect Mechanism.
Published in:
Journal of Neurochemistry, 1991, v. 57, n. 3, p. 1068, doi. 10.1111/j.1471-4159.1991.tb08258.x
By:
- Beal, M. Flint;
- Swartz, Kenton J.;
- Hyman, Bradley T.;
- Storey, Elsdon;
- Finn, Stephen F.;
- Koroshetz, Walter
Publication type:
Article
Kynurenine Pathway Measurements in Huntington's Disease Striatum: Evidence for Reduced Formation of Kynurenic Acid.
Published in:
Journal of Neurochemistry, 1990, v. 55, n. 4, p. 1327, doi. 10.1111/j.1471-4159.1990.tb03143.x
By:
- Beal, M. Flint;
- Matson, Wayne R.;
- Swartz, Kenton J.;
- Gamache, Paul H.;
- Bird, Edward D.
Publication type:
Article
Galanin-Like Immunoreactivity Is Unchanged in Alzheimer's Disease and Parkinson's Disease Dementia Cerebral Cortex.
Published in:
Journal of Neurochemistry, 1988, v. 51, n. 6, p. 1935, doi. 10.1111/j.1471-4159.1988.tb01181.x
By:
- Beal, M. Flint;
- Clevens, Ross A.;
- Chattha, Geetinder K.;
- MacGarvey, Usha M.;
- Mazurek, Michael F.;
- Gabriel, Steven M.
Publication type:
Article
Prospects for neuroprotective therapies in prodromal Huntington's disease.
Published in:
2014
By:
- Chandra, Abhishek;
- Johri, Ashu;
- Beal, M Flint
Publication type:
journal article
Prospects for neuroprotective therapies in prodromal Huntington's disease.
Published in:
Movement Disorders, 2014, v. 29, n. 3, p. 285, doi. 10.1002/mds.25835
By:
- Chandra, Abhishek;
- Johri, Ashu;
- Beal, M. Flint
Publication type:
Article
Mitochondrial therapies for Parkinson's disease.
Published in:
Movement Disorders, 2010, v. 25, n. S1, p. S155, doi. 10.1002/mds.22781
By:
- Thomas, Bobby;
- Beal, M. Flint
Publication type:
Article
Limited-time exposure to mitochondrial toxins may lead to chronic progressive neurodegenerative diseases.
Published in:
2000
By:
- Beal, M. Flint;
- Beal, M F
Publication type:
Editorial