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2'-deoxy-ADPR activates human TRPM2 faster than ADPR and thereby induces higher currents at physiological Ca<sup>2+</sup> concentrations.
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- Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1294357
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- Article
Daratumumab and Nanobody-Based Heavy Chain Antibodies Inhibit the ADPR Cyclase but not the NAD + Hydrolase Activity of CD38-Expressing Multiple Myeloma Cells.
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- Cancers, 2021, v. 13, n. 1, p. 76, doi. 10.3390/cancers13010076
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- Article
HN1L/JPT2: A signaling protein that connects NAADP generation to Ca<sup>2+</sup> microdomain formation.
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- Science Signaling, 2021, v. 14, n. 675, p. 1, doi. 10.1126/scisignal.abd5647
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- Article
The crystal structure of TRPM2 MHR1/2 domain reveals a conserved Zn<sup>2+</sup>‐binding domain essential for structural integrity and channel activity.
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- Protein Science: A Publication of the Protein Society, 2022, v. 31, n. 6, p. 1, doi. 10.1002/pro.4320
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- Article
Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349.
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- Biochemical Journal, 2017, v. 474, n. 13, p. 2159, doi. 10.1042/BCJ20170091
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- Article
ADP-ribosylation at R125 gates the P2X7 ion channel by presenting a covalent ligand to its nucleotide binding site.
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- FASEB Journal, 2008, v. 22, n. 3, p. 861, doi. 10.1096/fj.07-9294com
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- Article
Analysis of ligand binding and resulting conformational changes in pyrophosphatase NUDT9.
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- FEBS Journal, 2021, v. 288, n. 23, p. 6769, doi. 10.1111/febs.16097
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- Article
Frontrunners of T cell activation: Initial, localized Ca<sup>2+</sup> signals mediated by NAADP and the type 1 ryanodine receptor.
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- Science Signaling, 2015, v. 8, n. 398, p. 1, doi. 10.1126/scisignal.aab0863
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- Article
CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26134-w
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- Article
Alternative Splicing of the N-Terminal Cytosolic and Transmembrane Domains of P2X7 Controls Gating of the Ion Channel by ADP-Ribosylation.
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- PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0041269
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- Article
Modulation of Ca<sup>2+</sup> entry and plasma membrane potential by human TRPM4b.
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- FEBS Journal, 2007, v. 274, n. 3, p. 704, doi. 10.1111/j.1742-4658.2006.05614.x
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- Article
Potential role of the bitter taste receptor T2R14 in the prolonged survival and enhanced chemoresponsiveness induced by apigenin.
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- International Journal of Oncology, 2023, v. 62, n. 1, p. N.PAG
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- Article
Mouse CD38-Specific Heavy Chain Antibodies Inhibit CD38 GDPR-Cyclase Activity and Mediate Cytotoxicity Against Tumor Cells.
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- Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.703574
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- Article
Does Cyclic ADP-Ribose (cADPR) Activate the Non-selective Cation Channel TRPM2?
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- Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.02018
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- Article
A mathematical model of T lymphocyte calcium dynamics derived from single transmembrane protein properties.
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- Frontiers in Immunology, 2013, v. 4, p. 1, doi. 10.3389/fimmu.2013.00277
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- Article
Adenine nucleotides as paracrine mediators and intracellular second messengers in immunity and inflammation.
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- Biochemical Society Transactions, 2019, v. 47, n. 1, p. 329, doi. 10.1042/BST20180419
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- Article
cADPR Does Not Activate TRPM2.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 6, p. 3163, doi. 10.3390/ijms23063163
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- Article