Works by Flavell, Richard A.

Results: 335

Heterogeneity of IL-15-expressing mesenchymal stromal cells controls natural killer cell development and immune cell homeostasis.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61231-0

By:

Stecher, Carmen;
Bischl, Romana;
Schmid-Böse, Anna;
Ferstl, Stefanie;
Potzmann, Elisabeth;
Frank, Magdalena;
Braun, Nina;
Farlik, Matthias;
Flavell, Richard A.;
Herndler-Brandstetter, Dietmar

Publication type:

Article

Loss of Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4) Reveals a Requirement for MAPK Signalling in Mouse Sex Determination.

Published in:

PLoS Biology, 2009, v. 7, n. 9, p. 1, doi. 10.1371/journal.pbio.1000196

By:

Bogani, Debora;
Siggers, Pam;
Brixey, Rachel;
Warr, Nick;
Beddow, Sarah;
Edwards, Jessica;
Williams, Debbie;
Wilhelm, Dagmar;
Koopman, Peter;
Flavell, Richard A.;
Hongbo Chi;
Ostrer, Harry;
Wells, Sara;
Cheeseman, Michael;
Greenfield, Andy

Publication type:

Article

The Gilt market: Models and model-based trading.

Published in:

Journal of the Operational Research Society, 1994, v. 45, n. 4, p. 392, doi. 10.2307/2584211

By:

Flavell, Richard;
Meade, Nigel

Publication type:

Article

N‐Acyl Amides from Neisseria meningitidis and Their Role in Sphingosine Receptor Signaling.

Published in:

ChemBioChem, 2022, v. 23, n. 22, p. 1, doi. 10.1002/cbic.202200490

By:

Cho, Wooyoung;
York, Autumn G.;
Wang, Rurun;
Wyche, Thomas P.;
Piizzi, Grazia;
Flavell, Richard A.;
Crawford, Jason M.

Publication type:

Article

Organization and evolution of the class I gene family in the major histocompatibility complex of the C57BL/10 mouse.

Published in:

Nature, 1984, v. 310, n. 5979, p. 650, doi. 10.1038/310650a0

By:

Weiss, Elisabeth H.;
Golden, Lynn;
Fahrner, Karen;
Mellor, Andrew L.;
Devlin, James J.;
Bullman, Hilary;
Tiddens, Harm;
Bud, Harriet;
Flavell, Richard A.

Publication type:

Article

Genetic engineering: Prospects for transforming monocot crop plants.

Published in:

Nature, 1984, v. 307, n. 5947, p. 108, doi. 10.1038/307108a0

By:

Flavell, Richard;
Mathias, Raymond

Publication type:

Article

A potential donor gene for the bm1 gene conversion event in the C57BL mouse.

Published in:

Nature, 1983, v. 306, n. 5945, p. 792, doi. 10.1038/306792a0

By:

Mellor, Andrew L.;
Weiss, Elizabeth H.;
Ramachandran, K.;
Flavell, Richard A.

Publication type:

Article

The transcription cofactor Hopx is required for regulatory T cell function in dendritic cell-mediated peripheral T cell unresponsiveness.

Published in:

Nature Immunology, 2010, v. 11, n. 10, p. 962, doi. 10.1038/ni.1929

By:

Hawiger, Daniel;
Wan, Yisong Y.;
Eynon, Elizabeth E.;
Flavell, Richard A.

Publication type:

Article

The dual nature of TH17 cells: shifting the focus to function.

Published in:

Nature Immunology, 2010, v. 11, n. 6, p. 471, doi. 10.1038/ni.1882

By:

O'Connor, William;
Zenewicz, Lauren A;
Flavell, Richard A

Publication type:

Article

Thymic self-reactivity selects natural interleukin 17–producing T cells that can regulate peripheral inflammation.

Published in:

2010

By:

Marks, Benjamin R;
Nowyhed, Heba N;
Choi, Jin-Young;
Poholek, Amanda C;
Odegard, Jared M;
Flavell, Richard A;
Craft, Joe

Publication type:

Correction Notice

Defective survival of naive CD8+ T lymphocytes in the absence of the β3 regulatory subunit of voltage-gated calcium channels.

Published in:

Nature Immunology, 2009, v. 10, n. 12, p. 1275, doi. 10.1038/ni.1793

By:

Jha, Mithilesh K.;
Badou, Abdallah;
Meissner, Marcel;
McRory, John E.;
Freichel, Marc;
Flockerzi, Veit;
Flavell, Richard A.

Publication type:

Article

Thymic self-reactivity selects natural interleukin 17–producing T cells that can regulate peripheral inflammation.

Published in:

Nature Immunology, 2009, v. 10, n. 10, p. 1125, doi. 10.1038/ni.1783

By:

Benjamin R. Marks;
Nowyhed, Heba N.;
Jin-Young Choi;
Poholek, Amanda C.;
Odegard, Jared M.;
Flavell, Richard A.;
Craft, Joe

Publication type:

Article

Regulatory T cells that become autoaggressive.

Published in:

Nature Immunology, 2009, v. 10, n. 9, p. 938, doi. 10.1038/ni0909-938

By:

Hawiger, Daniel;
Flavell, Richard A.

Publication type:

Article

The receptor S1P1 overrides regulatory T cell–mediated immune suppression through Akt-mTOR.

Published in:

Nature Immunology, 2009, v. 10, n. 7, p. 769, doi. 10.1038/ni.1743

By:

Guangwei Liu;
Burns, Samir;
Gonghua Huang;
Boyd, Kelli;
Proia, Richard L.;
Flavell, Richard A.;
Hongbo Chi

Publication type:

Article

A protective function for interleukin 17A in T cell–mediated intestinal inflammation.

Published in:

Nature Immunology, 2009, v. 10, n. 6, p. 603, doi. 10.1038/ni.1736

By:

O'Connor Jr, William;
Kamanaka, Masahito;
Booth, Carmen J;
Town, Terrence;
Nakae, Susumu;
Iwakura, Yoichiro;
Kolls, Jay K;
Flavell, Richard A

Publication type:

Article

A dominant function for interleukin 27 in generating interleukin 10–producing anti-inflammatory T cells.

Published in:

Nature Immunology, 2007, v. 8, n. 12, p. 1380, doi. 10.1038/ni1541

By:

Awasthi, Amit;
Carrier, Yijun;
Peron, Jean P S;
Bettelli, Estelle;
Kamanaka, Masahito;
Flavell, Richard A;
Kuchroo, Vijay K;
Oukka, Mohamed;
Weiner, Howard L

Publication type:

Article

COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor–induced entry into the cell cycle from quiescence.

Published in:

Nature Immunology, 2007, v. 8, n. 11, p. 1236, doi. 10.1038/ni1514

By:

Menon, Suchithra;
Chi, Hongbo;
Zhang, Huiyong;
Deng, Xing Wang;
Flavell, Richard A;
Wei, Ning

Publication type:

Article

Erratum: Epigenetic regulation of Ifng expression.

Published in:

Nature Immunology, 2007, v. 8, n. 8, p. 893, doi. 10.1038/ni0807-893a

By:

Spilianakis, Charalampos G;
Flavell, Richard A

Publication type:

Article

Epigenetic regulation of Ifng expression.

Published in:

Nature Immunology, 2007, v. 8, n. 7, p. 681, doi. 10.1038/ni0707-681

By:

Spilianakis, Charalampos G;
Flavell, Richard A

Publication type:

Article

Signals mediated by transforming growth factor-β initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.

Published in:

Nature Immunology, 2006, v. 7, n. 11, p. 1151, doi. 10.1038/ni1391

By:

Veldhoen, Marc;
Hocking, Richard J.;
Flavell, Richard A.;
Stockinger, Brigitta

Publication type:

Article

The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.

Published in:

Nature Immunology, 2006, v. 7, n. 8, p. 851, doi. 10.1038/ni1355

By:

Wan, Yisong Y.;
Hongbo Chi;
Min Xie;
Schneider, Michael D.;
Flavell, Richard A.

Publication type:

Article

The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection.

Published in:

Nature Immunology, 2006, v. 7, n. 3, p. 318, doi. 10.1038/ni1305

By:

Zamboni, Dario S.;
Kobayashi, Koichi S.;
Kohlsdorf, Tiana;
Ogura, Yasunori;
Long, E. Michelle;
Vance, Russell E.;
Kuida, Keisuke;
Mariathasan, Sanjeev;
Dixit, Vishva M.;
Flavell, Richard A.;
Dietrich, William F.;
Roy, Craig R.

Publication type:

Article

Transforming growth factor-ßcontrols T helper type 1 cell development through regulation of natural killer cell interferon-?

Published in:

Nature Immunology, 2005, v. 6, n. 6, p. 600, doi. 10.1038/ni1197

By:

Laouar, Yasmina;
Sutterwala, Fayyaz S.;
Gorelik, Leonid;
Flavell, Richard A.

Publication type:

Article

Hypersensitive site 7 of the TH2 locus control region is essential for expressing TH2 cytokine genes and for long-range intrachromosomal interactions.

Published in:

Nature Immunology, 2005, v. 6, n. 1, p. 42, doi. 10.1038/ni1148

By:

Lee, Gap Ryol;
Spilianakis, Charalampos G.;
Flavell, Richard A.

Publication type:

Article

Long-range intrachromosomal interactions in the T helper type 2 cytokine locus.

Published in:

Nature Immunology, 2004, v. 5, n. 10, p. 1017, doi. 10.1038/ni1115

By:

Spilianakis, Charalampos G.;
Flavell, Richard A.

Publication type:

Article

Gadd45ß is important for perpetuating cognate and inflammatory signals in T cells.

Published in:

Nature Immunology, 2004, v. 5, n. 1, p. 38, doi. 10.1038/ni1020

By:

Binfeng Lu, Michael J.;
Ferrandino, Anthony F.;
Flavell, Richard A.

Publication type:

Article

Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways.

Published in:

Nature Immunology, 2003, v. 4, n. 12, p. 1223, doi. 10.1038/ni1010

By:

Hoebe, Kasper;
Janssen, Edith M.;
Kim, Sung O.;
Alexopoulou, Lena;
Flavell, Richard A.;
Jiahuai Han;
Beutler, Bruce

Publication type:

Article

Intracellular debugging.

Published in:

Nature Immunology, 2003, v. 4, n. 7, p. 652, doi. 10.1038/ni0703-652

By:

Kobayashi, Koichi S;
Eynon, Elizabeth E;
Flavell, Richard A

Publication type:

Article

Defective T cell activation and autoimmune disorder in Stra13-deficient mice.

Published in:

Nature Immunology, 2001, v. 2, n. 11, p. 1040, doi. 10.1038/ni721

By:

Sun, Hong;
Lu, Binfeng;
Li, Rong-Qin;
Flavell, Richard A.;
Taneja, Reshma

Publication type:

Article

Helper T cell differentiation: a role for SAP?

Published in:

Nature Immunology, 2001, v. 2, n. 5, p. 382, doi. 10.1038/87679

By:

Fields, Patrick E.;
Flavell, Richard A.

Publication type:

Article

Costimulation in Tolerance and Autoimmunity.

Published in:

International Reviews of Immunology, 1995, v. 13, n. 2, p. 135, doi. 10.3109/08830189509061743

By:

Guerder, Sylvie;
Flavell, Richard A.

Publication type:

Article

Wheat genetic resources have avoided disease pandemics, improved food security, and reduced environmental footprints: A review of historical impacts and future opportunities.

Published in:

Global Change Biology, 2024, v. 30, n. 8, p. 1, doi. 10.1111/gcb.17440

By:

King, Julie;
Dreisigacker, Susanne;
Reynolds, Matthew;
Bandyopadhyay, Anindya;
Braun, Hans‐Joachim;
Crespo‐Herrera, Leonardo;
Crossa, Jose;
Govindan, Velu;
Huerta, Julio;
Ibba, Maria Itria;
Robles‐Zazueta, Carlos A.;
Saint Pierre, Carolina;
Singh, Pawan K.;
Singh, Ravi P.;
Achary, V. Mohan Murali;
Bhavani, Sridhar;
Blasch, Gerald;
Cheng, Shifeng;
Dempewolf, Hannes;
Flavell, Richard B.

Publication type:

Article

Humanized MISTRG as a preclinical in vivo model to study human neutrophil-mediated immune processes.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 01, doi. 10.3389/fimmu.2023.1105103

By:

Martinez-Sanz, Paula;
Laurent, Adrien R. G.;
Slot, Edith;
Hoogenboezem, Mark;
Bąbała, Nikolina;
van Bruggen, Robin;
Rongvaux, Anthony;
Flavell, Richard A.;
Tytgat, Godelieve A. M.;
Franke, Katka;
Matlung, Hanke L.;
Kuijpers, Taco W.;
Amsen, Derk;
Karrich, Julien J.

Publication type:

Article

Legionella pneumophila Strain 130b Evades Macrophage Cell Death Independent of the Effector SidF in the Absence of Flagellin.

Published in:

Frontiers in Cellular & Infection Microbiology, 2017, v. 7, p. 1, doi. 10.3389/fcimb.2017.00035

By:

Speir, Mary;
Vogrin, Adam;
Seidi, Azadeh;
Abraham, Gilu;
Hunot, Stéphane;
Qingqing Han;
Dorn II, Gerald W.;
Masters, Seth L.;
Flavell, Richard A.;
Vince, James E.;
Naderer, Thomas

Publication type:

Article

About this issue.

Published in:

BioEssays, 1985, v. 3, n. 4, p. 147, doi. 10.1002/bies.950030402

By:

Flavell, Richard B.

Publication type:

Article

Teplizumab Induces Human Gut-Tropic Regulatory Cells in Humanized Mice and Patients.

Published in:

Science Translational Medicine, 2012, v. 4, n. 118, p. 1, doi. 10.1126/scitranslmed.3003401

By:

Waldron-Lynch, Frank;
Henegariu, Octavian;
Songyan Deng;
Preston-Hurlburt, Paula;
Tooley, James;
Flavell, Richard;
Herold, Kevan C.

Publication type:

Article

Decreased apoptosis in proliferative and postmitotic regions of the caspase 3-deficient embryonic central nervous system.

Published in:

Journal of Comparative Neurology, 2000, v. 423, n. 1, p. 1, doi. 10.1002/1096-9861(20000717)423:1<1::AID-CNE1>3.0.CO;2-S

By:

Pompeiano, Maria;
Blaschke, Anne Jeannette;
Flavell, Richard Antony;
Srinivasan, Anu;
Chun, Jerold

Publication type:

Article

Targeting autoantigen-specific T cells and suppression of autoimmune encephalomyelitis with receptor-modified T lymphocytes.

Published in:

Nature Biotechnology, 2002, v. 20, n. 12, p. 1215, doi. 10.1038/nbt758

By:

Jyothi, M. Divya;
Flavell, Richard A.;
Geiger, Terrence L.

Publication type:

Article

Death by numbers.

Published in:

Nature Biotechnology, 2000, v. 18, n. 7, p. 717, doi. 10.1038/77276

By:

Zheng, Timothy S.;
Flavell, Richard A.

Publication type:

Article

The Biotechnology Perspective.

Published in:

Nature Biotechnology, 1999, v. 17, p. 10, doi. 10.1038/70354

By:

Flavell, Richard B.

Publication type:

Article

Agriculture: a path of experiment and change.

Published in:

Nature Biotechnology, 1999, v. 17, p. 7, doi. 10.1038/7151

By:

Flavell, Richard B.

Publication type:

Article

Abrogated transforming growth factor beta receptor II (TGFβRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis.

Published in:

European Heart Journal, 2013, v. 34, n. 48, p. 3717, doi. 10.1093/eurheartj/ehs106

By:

Lievens, Dirk;
Habets, Kim L.;
Robertson, Anna-Karin;
Laouar, Yasmina;
Winkels, Holger;
Rademakers, Timo;
Beckers, Linda;
Wijnands, Erwin;
Boon, Louis;
Mosaheb, Munir;
Ait-Oufella, Hafid;
Mallat, Ziad;
Flavell, Richard A.;
Rudling, Mats;
Binder, Christoph J.;
Gerdes, Norbert;
Biessen, Erik A.L.;
Weber, Christian;
Daemen, Mat J.A.P.;
Kuiper, Johan

Publication type:

Article

Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice.

Published in:

EMBO Journal, 1999, v. 18, n. 7, p. 1845, doi. 10.1093/emboj/18.7.1845

By:

Hong-Tao Lu;
Yang, Derek D.;
Wysk, Mark;
Gatti, Evelina;
Mellman, Ira;
Davis, Roger J.;
Flavell, Richard A.

Publication type:

Article

Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation.

Published in:

EMBO Journal, 1999, v. 18, n. 2, p. 420, doi. 10.1093/emboj/18.2.420

By:

Baiyong Li;
Tournier, Cathy;
Davis, Roger J.;
Flavell, Richard A.

Publication type:

Article

Interferon-? expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway.

Published in:

1998

By:

Rincón, Mercedes;
Enslen, Hervé
Raingeaud, Joël;
Recht, Michael;
Zapton, Tyler;
Su, Michael S.-S.;
Penix, Laurie A.;
Davis, Roger J.;
Flavell, Richard A.

Publication type:

Proceeding

Interleukin-1 Receptor and Caspase-1 Are Required for the Th17 Response in Nitrogen Dioxide-Promoted Allergic Airway Disease.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2013, v. 48, n. 5, p. 655, doi. 10.1165/rcmb.2012-0423OC

By:

Martin, Rebecca A.;
Ather, Jennifer L.;
Lundblad, Lennart K. A.;
Suratt, Benjamin T.;
Boyson, Jonathan E.;
Budd, Ralph C.;
Alcorn, John F.;
Flavell, Richard A.;
Eisenbarth, Stephanie C.;
Poynter, Matthew E.

Publication type:

Article

Th17 cell plasticity towards a T-bet-dependent Th1 phenotype is required for bacterial control in Staphylococcus aureus infection.

Published in:

PLoS Pathogens, 2022, v. 18, n. 4, p. 1, doi. 10.1371/journal.ppat.1010430

By:

Bartsch, Patricia;
Kilian, Christoph;
Hellmig, Malte;
Paust, Hans-Joachim;
Borchers, Alina;
Sivayoganathan, Amirrtavarshni;
Enk, Leon;
Zhao, Yu;
Shaikh, Nikhat;
Büttner, Henning;
Wong, Milagros N.;
Puelles, Victor G.;
Wiech, Thorsten;
Flavell, Richard;
Huber, Tobias B.;
Turner, Jan-Eric;
Bonn, Stefan;
Huber, Samuel;
Gagliani, Nicola;
Mittrücker, Hans-Willi

Publication type:

Article

Bacterial Autoimmune Drug Metabolism Transforms an Immunomodulator into Structurally and Functionally Divergent Antibiotics.

Published in:

Angewandte Chemie, 2020, v. 132, n. 20, p. 7945, doi. 10.1002/ange.201916204

By:

Park, Hyun Bong;
Goddard, Tyler N.;
Oh, Joonseok;
Patel, Jaymin;
Wei, Zheng;
Perez, Corey E.;
Mercado, Brandon Q.;
Wang, Rurun;
Wyche, Thomas P.;
Piizzi, Grazia;
Flavell, Richard A.;
Crawford, Jason M.

Publication type:

Article

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants.

Published in:

Nature, 2008, v. 453, n. 7198, p. 1122, doi. 10.1038/nature06939

By:

Eisenbarth, Stephanie C.;
Colegio, Oscar R.;
O’Connor, William;
Sutterwala, Fayyaz S.;
Flavell, Richard A.

Publication type:

Article

Immunology: Cascade into clarity.

Published in:

Nature, 2008, v. 451, n. 7176, p. 254, doi. 10.1038/451254a

By:

Sutterwala, Fayyaz S.;
Flavell, Richard A.

Publication type:

Article