Works by Flatt, Peter R.
Results: 120
Therapeutic Potential of Medicinal Plants and Their Phytoconstituents in Diabetes, Cancer, Infections, Cardiovascular Diseases, Inflammation and Gastrointestinal Disorders.
- Published in:
- Biomedicines, 2025, v. 13, n. 2, p. 454, doi. 10.3390/biomedicines13020454
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- Article
Enzymatically stable analogue of the gut‐derived peptide xenin on beta‐cell transdifferentiation in high fat fed and insulin‐deficient Ins1<sup>Cre/+</sup>;Rosa26‐eYFP mice.
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- Diabetes/Metabolism Research & Reviews, 2021, v. 37, n. 3, p. 1, doi. 10.1002/dmrr.3384
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- Article
Exendin-4(Lys<sup>27</sup> PAL)/gastrin/xenin-8-Gln: A novel acylated GLP-1/gastrin/xenin hybrid peptide that improves metabolic status in obese-diabetic (ob/ob) mice.
- Published in:
- 2019
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- Publication type:
- journal article
Positive effects of GLP-1 receptor activation with liraglutide on pancreatic islet morphology and metabolic control in C57BL/KsJ db/ db mice with degenerative diabetes.
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- Diabetes/Metabolism Research & Reviews, 2015, v. 31, n. 3, p. 248, doi. 10.1002/dmrr.2608
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- Article
The role of glucagon- and somatostatin-secreting cells in the regulation of insulin release and beta-cell function in heterotypic pseudoislets.
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- Diabetes/Metabolism Research & Reviews, 2010, v. 26, n. 7, p. 525, doi. 10.1002/dmrr.1111
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- Article
Comparative Effects of GLP-1 and GLP-2 on Beta-Cell Function, Glucose Homeostasis and Appetite Regulation.
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- Biomolecules (2218-273X), 2024, v. 14, n. 12, p. 1520, doi. 10.3390/biom14121520
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- Article
Evidence for Involvement of GIP and GLP-1 Receptors and the Gut-Gonadal Axis in Regulating Female Reproductive Function in Mice.
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- Biomolecules (2218-273X), 2022, v. 12, n. 12, p. 1736, doi. 10.3390/biom12121736
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- Article
Cafeteria diet compromises natural adaptations of islet cell transdifferentiation and turnover in pregnancy.
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- Diabetic Medicine, 2025, v. 42, n. 1, p. 1, doi. 10.1111/dme.15434
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- Article
Vincent Marks (10 June 1930 to 6 November 2023).
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- 2024
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- Publication type:
- Obituary
Amplifying the antidiabetic actions of glucagon‐like peptide‐1: Potential benefits of new adjunct therapies.
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- Diabetic Medicine, 2021, v. 38, n. 12, p. 1, doi. 10.1111/dme.14699
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- Article
Emerging applications of metabolomic and genomic profiling in diabetic clinical medicine.
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- 2011
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- journal article
Emerging Applications of Metabolomic and Genomic Profiling in Diabetic Clinical Medicine.
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- Diabetes Care, 2011, v. 34, n. 12, p. 2624, doi. 10.2337/dc11-0837
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- Publication type:
- Article
Physiological and pharmacological regulation of insulin release: insights offered through exploitation of insulin-secreting cell lines.
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- Diabetes, Obesity & Metabolism, 1999, v. 1, n. 3, p. 137, doi. 10.1046/j.1463-1326.1999.00017.x
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- Publication type:
- Article
Comparison of the subchronic antidiabetic effects of DPP IV-resistant GIP and GLP-1 analogues in obese diabetic ( ob/ob) mice.
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- Journal of Peptide Science, 2007, v. 13, n. 6, p. 400, doi. 10.1002/psc.861
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- Article
Gut-Derived Peptide Hormone Analogues and Potential Treatment of Bone Disorders in Obesity and Diabetes Mellitus.
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- Clinical Medicine Insights: Endocrinology & Diabetes, 2024, p. 1, doi. 10.1177/11795514241238059
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- Article
Effects of 2 Novel PYY(1-36) Analogues, (P 3 L 31 P 34)PYY(1-36) and PYY(1-36)(Lys 12 PAL), on Pancreatic Beta-Cell Function, Growth, and Survival.
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- Clinical Medicine Insights: Endocrinology & Diabetes, 2019, v. 12, p. N.PAG, doi. 10.1177/1179551419855626
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- Article
Effects of 2 Novel PYY(1-36) Analogues, (P 3 L 31 P 34)PYY(1-36) and PYY(1-36)(Lys 12 PAL), on Pancreatic Beta-Cell Function, Growth, and Survival.
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- Clinical Medicine Insights: Endocrinology & Diabetes, 2019, v. 12, p. N.PAG, doi. 10.1177/1179551419855626
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- Publication type:
- Article
A novel neurotensin/xenin fusion peptide enhances ß-cell function and exhibits antidiabetic efficacy in high-fat fed mice.
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- Bioscience Reports, 2021, v. 41, n. 8, p. 1, doi. 10.1042/BSR20211275
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- Publication type:
- Article
Effects of 22 traditional anti-diabetic medicinal plants on DPP-IV enzyme activity and glucose homeostasis in high-fat fed obese diabetic rats.
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- Bioscience Reports, 2021, v. 41, n. 1, p. 1, doi. 10.1042/BSR20203824
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- Publication type:
- Article
Stable Incretin Mimetics Counter Rapid Deterioration of Bone Quality in Type 1 Diabetes Mellitus.
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- Journal of Cellular Physiology, 2015, v. 230, n. 12, p. 3009, doi. 10.1002/jcp.25033
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- Publication type:
- Article
N-acetyl-GLP-1: a DPP IV-resistant analogue of glucagon-like peptide-1 (GLP-1) with improved effects on pancreatic β-cell-associated gene expression
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- Cell Biology International, 2004, v. 28, n. 1, p. 69, doi. 10.1016/j.cellbi.2003.10.004
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- Publication type:
- Article
[P<sup>3</sup>]PP, a stable, long‐acting pancreatic polypeptide analogue, evokes weight lowering and pancreatic beta‐cell‐protective effects in obesity‐associated diabetes.
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- Diabetes, Obesity & Metabolism, 2024, v. 26, n. 11, p. 4945, doi. 10.1111/dom.15897
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- Publication type:
- Article
Pancreatic islet cell plasticity: Pathogenic or therapeutically exploitable?
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- Diabetes, Obesity & Metabolism, 2024, v. 26, n. 1, p. 16, doi. 10.1111/dom.15300
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- Publication type:
- Article
Beneficial metabolic effects of recurrent periods of beta‐cell rest and stimulation using stable neuropeptide Y1 and glucagon‐like peptide‐1 receptor agonists.
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- Diabetes, Obesity & Metabolism, 2022, v. 24, n. 12, p. 2353, doi. 10.1111/dom.14821
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- Publication type:
- Article
Weight‐reducing, lipid‐lowering and antidiabetic activities of a novel arginine vasopressin analogue acting at the V1a and V1b receptors in high‐fat‐fed mice.
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- Diabetes, Obesity & Metabolism, 2021, v. 23, n. 10, p. 2215, doi. 10.1111/dom.14462
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- Publication type:
- Article
Beneficial actions of a long‐acting apelin analogue in diabetes are related to positive effects on islet cell turnover and transdifferentiation.
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- Diabetes, Obesity & Metabolism, 2020, v. 22, n. 12, p. 2468, doi. 10.1111/dom.14177
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- Article
Role of exendin‐4 in the Gila monster: Further lessons regarding human oral glucagon‐like peptide‐1 therapy?
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- Diabetes, Obesity & Metabolism, 2020, v. 22, n. 12, p. 2509, doi. 10.1111/dom.14171
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- Publication type:
- Article
Peptide YY (1–36) peptides from phylogenetically ancient fish targeting mammalian neuropeptide Y1 receptors demonstrate potent effects on pancreatic β‐cell function, growth and survival.
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- Diabetes, Obesity & Metabolism, 2020, v. 22, n. 3, p. 404, doi. 10.1111/dom.13908
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- Publication type:
- Article
Beneficial long‐term antidiabetic actions of N‐ and C‐terminally modified analogues of apelin‐13 in diet‐induced obese diabetic mice.
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- Diabetes, Obesity & Metabolism, 2018, v. 20, n. 2, p. 319, doi. 10.1111/dom.13068
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- Publication type:
- Article
Effects of long-acting analogues of lamprey GLP-1 and paddlefish glucagon on alpha- to beta-cell transdifferentiation in an insulin-deficient transgenic mouse model.
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- Journal of Peptide Science, 2021, v. 27, n. 8, p. 1, doi. 10.1002/psc.3328
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- Publication type:
- Article
Assessment of the potential of temporin peptides from the frog Rana temporaria (Ranidae) as anti-diabetic agents.
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- Journal of Peptide Science, 2018, v. 24, n. 2, p. 1, doi. 10.1002/psc.3065
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- Publication type:
- Article
Cytotoxic peptides with insulin-releasing activities from skin secretions of the Italian stream frog Rana italica (Ranidae).
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- Journal of Peptide Science, 2017, v. 23, n. 10, p. 769, doi. 10.1002/psc.3025
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- Article
Enteroendocrine K Cells Exert Complementary Effects to Control Bone Quality and Mass in Mice.
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- Journal of Bone & Mineral Research, 2020, v. 35, n. 7, p. 1363, doi. 10.1002/jbmr.4004
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- Article
Chemical ablation of gastric inhibitory polypeptide receptor action by daily (Pro3)GIP administration improves glucose tolerance and ameliorates insulin resistance and abnormalities of islet structure in obesity-related diabetes.
- Published in:
- 2005
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- Publication type:
- journal article
Chemical Ablation of Gastric Inhibitory Polypeptide Receptor Action by Daily (Pro<sup>3</sup>)GIP Administration Improves Glucose Tolerance and Ameliorates Insulin Resistance and Abnormalities of Islet Structure in Obesity-Related Diabetes.
- Published in:
- Diabetes, 2005, v. 54, n. 8, p. 2436, doi. 10.2337/diabetes.54.8.2436
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- Publication type:
- Article
Demonstration of glycated insulin in human diabetic plasma and decreased biological activity assessed by euglycemic-hyperinsulinemic clamp technique in humans.
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- 2003
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- Publication type:
- journal article
A nuclear magnetic resonance-based demonstration of substantial oxidative L-alanine metabolism and L-alanine-enhanced glucose metabolism in a clonal pancreatic beta-cell line: metabolism of L-alanine is important to the regulation of insulin secretion.
- Published in:
- 2002
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- Publication type:
- journal article
Overexpression of the Na/Ca exchanger shapes stimulus-induced cytosolic Ca(2+) oscillations in insulin-producing BRIN-BD11 cells.
- Published in:
- 2002
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- Publication type:
- journal article
Overexpression of the Na/Ca Exchanger Shapes Stimulus-Induced Cytosolic Ca<sup>2+</sup>; Oscillations in Insulin-Producing BRIN-BD11 Cells.
- Published in:
- Diabetes, 2002, v. 51, n. 2, p. 367, doi. 10.2337/diabetes.51.2.366
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- Publication type:
- Article
ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line.
- Published in:
- 1999
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- Publication type:
- journal article
NH[sub 2]-terminally modified gastric inhibitory polypeptide exhibits amino-peptidase resistance and enhanced antihyperglycemic activity.
- Published in:
- Diabetes, 1999, v. 48, n. 4, p. 758, doi. 10.2337/diabetes.48.4.758
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- Publication type:
- Article
Glycated cholecystokinin-8 has an enhanced satiating activity and is protected against enzymatic degradation.
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- 1998
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- Publication type:
- journal article
Glycation of insulin in the islets of Langerhans of normal and diabetic animals.
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- 1996
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- Publication type:
- journal article
Characterization of a novel glucose-responsive insulin-secreting cell line, BRIN-BD11, produced by electrofusion.
- Published in:
- 1996
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- Publication type:
- journal article
Individual and combined effects of GIP and xenin on differentiation, glucose uptake and lipolysis in 3T3-L1 adipocytes.
- Published in:
- Biological Chemistry, 2020, v. 401, n. 11, p. 1293, doi. 10.1515/hsz-2020-0195
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- Publication type:
- Article
Zinc-induced activation of GPR39 regulates glucose homeostasis through glucose-dependent insulinotropic polypeptide secretion from enteroendocrine K-cells.
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- Biological Chemistry, 2019, v. 400, n. 8, p. 1023, doi. 10.1515/hsz-2018-0393
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- Publication type:
- Article
Locally produced xenin and the neurotensinergic system in pancreatic islet function and β-cell survival.
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- Biological Chemistry, 2018, v. 399, n. 1, p. 79, doi. 10.1515/hsz-2017-0136
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- Publication type:
- Article
Molecular mechanisms mediating the beneficial metabolic effects of [Arg<sup>4</sup>] tigerinin-1R in mice with diet-induced obesity and insulin resistance.
- Published in:
- Biological Chemistry, 2016, v. 397, n. 8, p. 753, doi. 10.1515/hsz-2016-0120
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- Publication type:
- Article
Activation of GPR119 by fatty acid agonists augments insulin release from clonal ß-cells and isolated pancreatic islets and improves glucose tolerance in mice.
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- Biological Chemistry, 2014, v. 395, n. 4, p. 453, doi. 10.1515/hsz-2013-0255
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- Publication type:
- Article
Effects of lipotoxicity on a novel insulin-secreting human pancreatic β-cell line, 1.1B4.
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- Biological Chemistry, 2013, v. 394, n. 7, p. 909, doi. 10.1515/hsz-2013-0115
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- Publication type:
- Article