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Targeting lysine demethylase 5 (KDM5) in mantle cell lymphoma.
Published in:
2024
By:
- Xu, Danmei;
- Bewicke-Copley, Findlay;
- Close, Karina;
- Okosun, Jessica;
- Gale, Robert Peter;
- Apperley, Jane;
- Weinstock, David M.;
- Wendel, Hans-Guido;
- Fitzgibbon, Jude
Publication type:
Letter
Identification of Recurrent Mutations in the microRNA-Binding Sites of B-Cell Lymphoma-Associated Genes in Follicular Lymphoma.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 22, p. 8795, doi. 10.3390/ijms21228795
By:
- Larrea, Erika;
- Fernandez-Mercado, Marta;
- Guerra-Assunção, José Afonso;
- Wang, Jun;
- Goicoechea, Ibai;
- Gaafar, Ayman;
- Ceberio, Izaskun;
- Lobo, Carmen;
- Okosun, Jessica;
- Enright, Anton J.;
- Fitzgibbon, Jude;
- Lawrie, Charles H.
Publication type:
Article
Drug ranking using machine learning systematically predicts the efficacy of anti-cancer drugs.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22170-8
By:
- Gerdes, Henry;
- Casado, Pedro;
- Dokal, Arran;
- Hijazi, Maruan;
- Akhtar, Nosheen;
- Osuntola, Ruth;
- Rajeeve, Vinothini;
- Fitzgibbon, Jude;
- Travers, Jon;
- Britton, David;
- Khorsandi, Shirin;
- Cutillas, Pedro R.
Publication type:
Article
BLUEPRINT to decode the epigenetic signature written in blood.
Published in:
Nature Biotechnology, 2012, v. 30, n. 3, p. 224, doi. 10.1038/nbt.2153
By:
- Adams, David;
- Altucci, Lucia;
- Antonarakis, Stylianos E;
- Ballesteros, Juan;
- Beck, Stephan;
- Bird, Adrian;
- Bock, Christoph;
- Boehm, Bernhard;
- Campo, Elias;
- Caricasole, Andrea;
- Dahl, Fredrik;
- Dermitzakis, Emmanouil T;
- Enver, Tariq;
- Esteller, Manel;
- Estivill, Xavier;
- Ferguson-Smith, Anne;
- Fitzgibbon, Jude;
- Flicek, Paul;
- Giehl, Claudia;
- Graf, Thomas
Publication type:
Article
Germline predisposition to haematological malignancies: Best practice consensus guidelines from the UK Cancer Genetics Group (UKCGG), CanGene‐CanVar and the NHS England Haematological Oncology Working Group.
Published in:
British Journal of Haematology, 2023, v. 201, n. 1, p. 25, doi. 10.1111/bjh.18675
By:
- Speight, Beverley;
- Hanson, Helen;
- Turnbull, Clare;
- Hardy, Steven;
- Drummond, James;
- Khorashad, Jamshid;
- Wragg, Christopher;
- Page, Paula;
- Parkin, Nicholas W.;
- Rio‐Machin, Ana;
- Fitzgibbon, Jude;
- Kulasekararaj, Austin Gladston;
- Hamblin, Angela;
- Talley, Polly;
- McVeigh, Terri P.;
- Snape, Katie
Publication type:
Article
Germline ERCC excision repair 6 like 2 (ERCC6L2) mutations lead to impaired erythropoiesis and reshaping of the bone marrow microenvironment.
Published in:
British Journal of Haematology, 2022, v. 199, n. 5, p. 754, doi. 10.1111/bjh.18466
By:
- Armes, Hannah;
- Bewicke‐Copley, Findlay;
- Rio‐Machin, Ana;
- Di Bella, Doriana;
- Philippe, Céline;
- Wozniak, Anna;
- Tummala, Hemanth;
- Wang, Jun;
- Ezponda, Teresa;
- Prosper, Felipe;
- Dokal, Inderjeet;
- Vulliamy, Tom;
- Kilpivaara, Outi;
- Wartiovaara‐Kautto, Ulla;
- Fitzgibbon, Jude;
- Rouault‐Pierre, Kevin
Publication type:
Article
AML through the prism of molecular genetics.
Published in:
British Journal of Haematology, 2020, v. 188, n. 1, p. 49, doi. 10.1111/bjh.16356
By:
- Charrot, Sarah;
- Armes, Hannah;
- Rio‐Machin, Ana;
- Fitzgibbon, Jude
Publication type:
Article
Myeloblative therapy with autologous haematopoietic stem cell support as consolidation of first remission in acute myeloid leukaemia - very long follow-up.
Published in:
British Journal of Haematology, 2014, v. 167, n. 5, p. 724, doi. 10.1111/bjh.13055
By:
- Rohatiner, Ama Z. S.;
- Smith, Matthew L.;
- Spinelli, Orietta;
- Rambaldi, Alessandro;
- Bassan, Renato;
- Bona, Eros;
- Rodeghiero, Francesco;
- Raimondi, Roberto;
- Björkholm, Magnus;
- Johnson, Steve;
- Newland, Adrian C.;
- Cavenagh, Jamie D.;
- Macdougall, Finlay;
- Waters, Rachel;
- Fitzgibbon, Jude;
- Barbui, Tiziano;
- Lister, Andrew
Publication type:
Article
GATA2 mutations in sporadic and familial acute myeloid leukaemia patients with CEBPA mutations.
Published in:
British Journal of Haematology, 2013, v. 161, n. 5, p. 701, doi. 10.1111/bjh.12317
By:
- Green, Claire L.;
- Tawana, Kiran;
- Hills, Robert K.;
- Bödör, Csaba;
- Fitzgibbon, Jude;
- Inglott, Sarah;
- Ancliff, Phil;
- Burnett, Alan K.;
- Linch, David C.;
- Gale, Rosemary E.
Publication type:
Article
It's a targeted world in non-Hodgkin's lymphoma.
Published in:
2011
By:
- Okosun, Jessica;
- Fitzgibbon, Jude
Publication type:
Opinion
High Throughput Sequencing Analysis of the Immunoglobulin Heavy Chain Gene from Flow-Sorted B Cell Sub-Populations Define the Dynamics of Follicular Lymphoma Clonal Evolution.
Published in:
PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0134833
By:
- Carlotti, Emanuela;
- Wrench, David;
- Rosignoli, Guglielmo;
- Marzec, Jacek;
- Sangaralingam, Ajanthah;
- Hazanov, Lena;
- Michaeli, Miri;
- Hallam, Simon;
- Chaplin, Tracy;
- Iqbal, Sameena;
- Calaminici, Maria;
- Young, Bryan;
- Mehr, Ramit;
- Campbell, Peter;
- Fitzgibbon, Jude;
- Gribben, John G.
Publication type:
Article
Functional Analysis of a Breast Cancer-Associated FGFR2 Single Nucleotide Polymorphism Using Zinc Finger Mediated Genome Editing.
Published in:
PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0078839
By:
- Robbez-Masson, Luisa J.;
- Bödör, Csaba;
- Jones, J. Louise;
- Hurst, Helen C.;
- Fitzgibbon, Jude;
- Hart, Ian R.;
- Grose, Richard P.
Publication type:
Article
Mutations of the PU.1 Ets domain are specifically associated with murine radiation-induced, but not human therapy-related, acute myeloid leukaemia.
Published in:
Oncogene, 2005, v. 24, n. 22, p. 3678, doi. 10.1038/sj.onc.1208422
By:
- Suraweera, Nirosha;
- Meijne, Emmy;
- Moody, John;
- Carvajal-Carmona, Luis G;
- Yoshida, Kazuko;
- Pollard, Patrick;
- Fitzgibbon, Jude;
- Riches, Andrew;
- van Laar, Theo;
- Huiskamp, Rene;
- Rowan, Andrew;
- Tomlinson, Ian P. M.;
- Silver, Andrew
Publication type:
Article
A novel RUNX1 mutation in a kindred with familial platelet disorder with propensity to acute myeloid leukaemia: male predominance of affected individuals.
Published in:
European Journal of Haematology, 2010, v. 85, n. 6, p. 552, doi. 10.1111/j.1600-0609.2010.01513.x
By:
- Langabeer, Stephen E.;
- Owen, Carolyn J.;
- McCarron, Sarah L.;
- Fitzgibbon, Jude;
- Smith, Owen P.;
- O'Marcaigh, Aengus;
- Browne, Paul
Publication type:
Article
Mesenchymal niche remodeling impairs hematopoiesis via stanniocalcin 1 in acute myeloid leukemia.
Published in:
2020
By:
- Waclawiczek, Alexander;
- Hamilton, Ashley;
- Rouault-Pierre, Kevin;
- Abarrategi, Ander;
- Garcia Albornoz, Manuel;
- Miraki-Moud, Farideh;
- Bah, Nourdine;
- Gribben, John;
- Fitzgibbon, Jude;
- Taussig, David;
- Bonnet, Dominique;
- Albornoz, Manuel Garcia
Publication type:
journal article
The Molecular Pathogenesis of Acute Myeloid Leukemia.
Published in:
Current Medical Literature: Leukemia & Lymphoma, 2013, v. 21, n. 3, p. 67
By:
- Tawana, Kiran;
- Bödör, Csaba;
- Cavenagh, Jamie;
- Jenner, Michael;
- Fitzgibbon, Jude
Publication type:
Article
Genetics of Transformed Follicular Lymphoma.
Published in:
Hemato, 2022, v. 3, n. 4, p. 615, doi. 10.3390/hemato3040042
By:
- Alcoceba, Miguel;
- García-Álvarez, María;
- Okosun, Jessica;
- Ferrero, Simone;
- Ladetto, Marco;
- Fitzgibbon, Jude;
- García-Sanz, Ramón
Publication type:
Article
Characterization of the cDNA Coding for Mouse Prothrombin and Localization of the Gene on Mouse Chromosome 2.
Published in:
DNA & Cell Biology, 1990, v. 9, n. 7, p. 487, doi. 10.1089/dna.1990.9.487
By:
- DEGEN, SANDRA J. FRIEZNER;
- SCHAEFER, LORIE A.;
- JAMISON, C. SCOTT;
- GRANT, STEPHEN G.;
- FITZGIBBON, JUDE J.;
- PAI, JENN-ANN;
- CHAPMAN, VERNE M.;
- ELLIOTT, ROSEMARY W.
Publication type:
Article
Mutations of CEBPA in acute myeloid leukemia FAB types M1 and M2.
Published in:
Genes, Chromosomes & Cancer, 2003, v. 37, n. 1, p. 72, doi. 10.1002/gcc.10185
By:
- Jennifer Snaddon;
- Matthew L. Smith;
- Michael Neat;
- Maxine Cambal-Parrales;
- Amanda Dixon-McIver;
- Rachael Arch;
- John A. Amess;
- Ama Z. Rohatiner;
- T. Andrew Lister;
- Jude Fitzgibbon
Publication type:
Article
Localisation of a novel region of recurrent amplification in follicular lymphoma to an ∼6.8 Mb region of 13q32-33.
Published in:
Genes, Chromosomes & Cancer, 2001, v. 32, n. 3, p. 236, doi. 10.1002/gcc.1187
By:
- Neat, Michael J.;
- Foot, Nicola;
- Jenner, Michael;
- Goff, Lindsey;
- Ashcroft, Kevin;
- Burford, Deborah;
- Dunham, Andy;
- Norton, Andrew;
- Lister, T. Andrew;
- Fitzgibbon, Jude
Publication type:
Article
Follicular lymphoma: State-of-the-art ICML workshop in Lugano 2015.
Published in:
2017
By:
- Gascoyne, Randy D.;
- Nadel, Bertrand;
- Pasqualucci, Laura;
- Fitzgibbon, Jude;
- Payton, Jacqueline E.;
- Melnick, Ari;
- Weigert, Oliver;
- Tarte, Karin;
- Gribben, John G.;
- Friedberg, Jonathan W.;
- Seymour, John F.;
- Cavalli, Franco;
- Zucca, Emanuele
Publication type:
journal article
The clinical relevance of Wilms Tumour 1 (WT1) gene mutations in acute leukaemia.
Published in:
2010
By:
- Owen C;
- Fitzgibbon J;
- Paschka P;
- Owen, Carolyn;
- Fitzgibbon, Jude;
- Paschka, Peter
Publication type:
journal article
The clinical relevance of Wilms Tumour 1 ( WT1) gene mutations in acute leukaemia.
Published in:
Hematological Oncology, 2010, v. 28, n. 1, p. 13, doi. 10.1002/hon.931
By:
- Owen, Carolyn;
- Fitzgibbon, Jude;
- Paschka, Peter
Publication type:
Article
Serum selenium concentration at diagnosis and outcome in patients with haematological malignancies.
Published in:
British Journal of Haematology, 2011, v. 154, n. 4, p. 448, doi. 10.1111/j.1365-2141.2011.08744.x
By:
- Stevens, Jane;
- Waters, Rachel;
- Sieniawska, Christina;
- Kassam, Shireen;
- Montoto, Silvia;
- Fitzgibbon, Jude;
- Rohatiner, Ama;
- Lister, Andrew;
- Joel, Simon
Publication type:
Article
Familial myelodysplasia and acute myeloid leukaemia – a review.
Published in:
British Journal of Haematology, 2008, v. 140, n. 2, p. 123, doi. 10.1111/j.1365-2141.2007.06909.x
By:
- Owen, Carolyn;
- Barnett, Michael;
- Fitzgibbon, Jude
Publication type:
Article
Transformation of follicular lymphoma to diffuse large B-cell lymphoma proceeds by distinct oncogenic mechanisms.
Published in:
British Journal of Haematology, 2007, v. 136, n. 2, p. 286, doi. 10.1111/j.1365-2141.2006.06439.x
By:
- Davies, Andrew J.;
- Rosenwald, Andreas;
- Wright, George;
- Lee, Abigail;
- Last, Kim W.;
- Weisenburger, Dennis D.;
- Chan, Wing C.;
- Delabie, Jan;
- Braziel, Rita M.;
- Campo, Elias;
- Gascoyne, Randy D.;
- Jaffe, Elaine S.;
- Konrad Muller-Hermelink, H.;
- Ott, German;
- Calaminici, Maria;
- Norton, Andrew J.;
- Goff, Lindsey K.;
- Fitzgibbon, Jude;
- Staudt, Louis M.;
- Andrew Lister, T.
Publication type:
Article
Development of a quantitative real-time polymerase chain reaction method for monitoring CEBPA mutations in normal karyotype acute myeloid leukaemia.
Published in:
2006
By:
- Smith, Lan-Lan;
- Pearce, Daniel;
- Smith, Matthew L.;
- Jenner, Michael;
- Lister, T. Andrew;
- Bonnet, Dominique;
- Goff, Lindsey;
- Fitzgibbon, Jude
Publication type:
Letter
Development of a human acute myeloid leukaemia screening panel and consequent identification of novel gene mutation inFLT3andCCND3.
Published in:
British Journal of Haematology, 2005, v. 128, n. 3, p. 318, doi. 10.1111/j.1365-2141.2004.05324.x
By:
- Smith, Matthew L.;
- Arch, Rachael;
- Smith, Lan-Lan;
- Bainton, Nigel;
- Neat, Michael;
- Taylor, Claire;
- Bonnet, Dominique;
- Cavenagh, Jamie D.;
- Andrew Lister, T.;
- Fitzgibbon, Jude
Publication type:
Article
short report Reliable detection of clonal IgH/Bcl2 MBR rearrangement in follicular lymphoma: methodology and clinical significance.
Published in:
British Journal of Haematology, 2004, v. 124, n. 3, p. 325, doi. 10.1046/j.1365-2141.2003.04796.x
By:
- Iqbal, Sameena;
- Jenner, Michael J.R.;
- Summers, Karin E.;
- Davies, Andrew J.;
- Matthews, Janet;
- Norton, Andrew J.;
- Calaminici, Maria;
- Rohatiner, Ama Z.;
- Fitzgibbon, Jude;
- Lister, T. Andrew;
- Goff, Lindsey K.
Publication type:
Article
Papers to be published in forthcoming issues.
Published in:
2004
By:
- Summers, Karin E.;
- Davies, Andrew J.;
- Matthews, Janet;
- Norton, Andrew J.;
- Calaminici, Maria;
- Rohatiner, Ama Z.;
- Fitzgibbon, Jude;
- Lister, T. Andrew;
- Goff, Lindsey K.
Publication type:
Other
JH probe real-time quantitative polymerase chain reaction assay for Bcl-2/IgH rearrangements.
Published in:
British Journal of Haematology, 2002, v. 118, n. 2, p. 550, doi. 10.1046/j.1365-2141.2002.03623.x
By:
- Jenner, Michael J.;
- Summers, Karin E.;
- Norton, Andrew J.;
- Amess, John A.;
- Arch, Rachael S.;
- Young, Bryan D.;
- Lister, T. Andrew;
- Fitzgibbon, Jude;
- Goff, Lindsey K.
Publication type:
Article
The relative role of peripheral blood and bone marrow for monitoring molecular evidence of disease in follicular lymphoma by quantitative real-time polymerase chain reaction.
Published in:
British Journal of Haematology, 2002, v. 118, n. 2, p. 563, doi. 10.1046/j.1365-2141.2002.03641.x
By:
- Summers, Karin E.;
- Davies, Andrew J.;
- Matthews, Janet;
- Jenner, Michael J.;
- Cornelius, Victoria;
- Amess, John A.;
- Norton, Andrew J.;
- Rohatiner, Ama Z. S.;
- Fitzgibbon, Jude;
- Lister, T. Andrew;
- Goff, Lindsey K.
Publication type:
Article
CORRESPONDENCEFamilial follicular lymphoma: A Case Report with Molecular Analysis.
Published in:
British Journal of Haematology, 2000, v. 110, n. 3, p. 744, doi. 10.1046/j.1365-2141.2000.02239-2.x
By:
- Last, Kim W.;
- Goff, Lindsey K.;
- Summers, Karin E.;
- Neat, Michael;
- Jenner, Michael;
- Crawley, Charles;
- Fitzgibbon, Jude;
- Rohatiner, Ama Z.;
- Lister, T. Andrew
Publication type:
Article
Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes.
Published in:
Signal Transduction & Targeted Therapy, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41392-022-01288-1
By:
- Casado, Pedro;
- Rio-Machin, Ana;
- Miettinen, Juho J.;
- Bewicke-Copley, Findlay;
- Rouault-Pierre, Kevin;
- Krizsan, Szilvia;
- Parsons, Alun;
- Rajeeve, Vinothini;
- Miraki-Moud, Farideh;
- Taussig, David C.;
- Bödör, Csaba;
- Gribben, John;
- Heckman, Caroline;
- Fitzgibbon, Jude;
- Cutillas, Pedro R.
Publication type:
Article
CKS1 inhibition depletes leukemic stem cells and protects healthy hematopoietic stem cells in acute myeloid leukemia.
Published in:
Science Translational Medicine, 2022, v. 14, n. 650, p. 1, doi. 10.1126/scitranslmed.abn3248
By:
- Grey, William;
- Rio-Machin, Ana;
- Casado, Pedro;
- Grönroos, Eva;
- Ali, Sara;
- Miettinen, Juho J.;
- Bewicke-Copley, Findlay;
- Parsons, Alun;
- Heckman, Caroline A.;
- Swanton, Charles;
- Cutillas, Pedro R.;
- Gribben, John;
- Fitzgibbon, Jude;
- Bonnet, Dominique
Publication type:
Article
A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma.
Published in:
Genome Medicine, 2014, v. 6, n. 12, p. 1, doi. 10.1186/s13073-014-0105-3
By:
- Haider, Syed;
- Jun Wang;
- Nagano, Ai;
- Desai, Ami;
- Arumugam, Prabhu;
- Dumartin, Laurent;
- Fitzgibbon, Jude;
- Hagemann, Thorsten;
- Marshall, John F.;
- Kocher, Hemant M.;
- Crnogorac-Jurcevic, Tatjana;
- Scarpa, Aldo;
- Lemoine, Nicholas R.;
- Chelala, Claude
Publication type:
Article
Tumour necrosis factor polymorphisms and susceptibility to follicular lymphoma.
Published in:
British Journal of Haematology, 1999, v. 107, n. 2, p. 388, doi. 10.1046/j.1365-2141.1999.01704.x
By:
- Fitzgibbon, Jude;
- Grenzelias, Demetrios;
- Matthews, Janet;
- Lister, T. Andrew;
- Gupta, Rajnish K.
Publication type:
Article

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