Works by Fischer, Stephan

Results: 50

Controlling Cellular Uptake and Toxicity of Polyphenylene Dendrimers by Chemical Functionalization.

Published in:

ChemBioChem, 2017, v. 18, n. 10, p. 960, doi. 10.1002/cbic.201700079

By:

Hammer, Brenton A. G.;
Wu, Yuzhou;
Fischer, Stephan;
Liu, Weina;
Weil, Tanja;
Müllen, Klaus

Publication type:

Article

Three-dimensional kinematics of the craniocervical junction of Cavalier King Charles Spaniels compared to Chihuahuas and Labrador retrievers.

Published in:

PLoS ONE, 2023, v. 18, n. 1, p. 1, doi. 10.1371/journal.pone.0278665

By:

Nickel, Mareike-Kristin;
Schikowski, Lisa;
Fischer, Martin Stephan;
Kelleners, Nicola;
Schmidt, Martin Jürgen;
Eley, Nele

Publication type:

Article

Lysine 156 promotes the anomalous proenzyme activity of tPA: X-ray crystal structure of single-chain human tPA.

Published in:

EMBO Journal, 1997, v. 16, n. 16, p. 4797, doi. 10.1093/emboj/16.16.4797

By:

Renatus, Martin;
Engh, Richard A.;
Stubbs, Milton T.;
Huber, Robert;
Fischer, Stephan;
Kohnert, Ulirich;
Bode, Wolfram

Publication type:

Article

Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos.

Published in:

BMC Biology, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1741-7007-11-69

By:

Fischer, Stephan;
Klüver, Nils;
Burkhardt-Medicke, Kathleen;
Pietsch, Mirko;
Schmidt, Anne-Marie;
Wellner, Peggy;
Schirmer, Kristin;
Luckenbach, Till

Publication type:

Article

The zebrafish embryo model in environmental risk assessment—applications beyond acute toxicity testing.

Published in:

Environmental Science & Pollution Research, 2008, v. 15, n. 5, p. 394, doi. 10.1007/s11356-008-0018-z

By:

Scholz, Stefan;
Fischer, Stephan;
Gündel, Ulrike;
Küster, Eberhard;
Luckenbach, Till;
Voelker, Doris

Publication type:

Article

Defining the extent of gene function using ROC curvature.

Published in:

Bioinformatics, 2022, v. 38, n. 24, p. 5390, doi. 10.1093/bioinformatics/btac692

By:

Fischer, Stephan;
Gillis, Jesse

Publication type:

Article

Clostridial C3 toxins target monocytes/macrophages and modulate their functions.

Published in:

Frontiers in Immunology, 2015, p. 1, doi. 10.3389/fimmu.2015.00339

By:

Barth, Holger;
Fischer, Stephan;
Möglich, Amelie;
Förtsch, Christina

Publication type:

Article

Relationships between impact variables from running in 20 different footwear conditions.

Published in:

Footwear Science, 2011, v. 3, p. 50, doi. 10.1080/19424280.2011.575806

By:

Fischer, Stephan;
Hennig, Ewald

Publication type:

Article

Relationships between impact variables from running in 20 different footwear conditions.

Published in:

Footwear Science, 2011, v. 3, p. S50, doi. 10.1080/19424280.2011.575806

By:

Fischer, Stephan;
Hennig, Ewald

Publication type:

Article

Active site labeling with dansyl-glutamyl-glycyl-arginyl chloromethyl ketone demonstrates the full activity of the refolded and purified tissue-type plasminogen activator variant BM 06.022.

Published in:

Molecular Biotechnology, 1995, v. 55, n. 2, p. 157, doi. 10.1007/BF02783556

By:

Kohnert, Ulrich;
Wozny, Manfred;
Llinas, Manuel;
Roos, Anita;
Fischer, Stephan

Publication type:

Article

A Supramolecular Approach toward Bioinspired PAMAM-Dendronized Fusion Toxins.

Published in:

Macromolecular Bioscience, 2016, v. 16, n. 6, p. 803, doi. 10.1002/mabi.201500417

By:

Kuan, Seah Ling;
Förtsch, Christina;
Ng, David Yuen Wah;
Fischer, Stephan;
Tokura, Yu;
Liu, Weina;
Wu, Yuzhou;
Koynov, Kaloian;
Barth, Holger;
Weil, Tanja

Publication type:

Article

Macromol. Biosci. 6/2016.

Published in:

Macromolecular Bioscience, 2016, v. 16, n. 6, p. 785, doi. 10.1002/mabi.201670022

By:

Kuan, Seah Ling;
Förtsch, Christina;
Ng, David Yuen Wah;
Fischer, Stephan;
Tokura, Yu;
Liu, Weina;
Wu, Yuzhou;
Koynov, Kaloian;
Barth, Holger;
Weil, Tanja

Publication type:

Article

The Compound U18666A Inhibits the Intoxication of Cells by Clostridioides difficile Toxins TcdA and TcdB.

Published in:

Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.784856

By:

Papatheodorou, Panagiotis;
Kindig, Selina;
Badilla-Lobo, Adriana;
Fischer, Stephan;
Durgun, Ebru;
Thuraisingam, Tharani;
Witte, Alexander;
Song, Shuo;
Aktories, Klaus;
Chaves-Olarte, Esteban;
Rodríguez, César;
Barth, Holger

Publication type:

Article

Geschichte als Theorie der Gelegenheiten oder der Simulationsnexus geschichts- wissenschaftlicher Erklärungen.

Published in:

Österreichische Zeitschrift für Geschichtswissenschaften, 2009, v. 20, n. 1, p. 131

By:

Fischer, Stephan M.

Publication type:

Article

Human α-Defensin-6 Neutralizes Clostridioides difficile Toxins TcdA and TcdB by Direct Binding.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 9, p. 4509, doi. 10.3390/ijms23094509

By:

Barthold, Lara;
Heber, Sebastian;
Schmidt, Christoph Q.;
Gradl, Marion;
Weidinger, Gilbert;
Barth, Holger;
Fischer, Stephan

Publication type:

Article

A Model for Genome Size Evolution.

Published in:

Bulletin of Mathematical Biology, 2014, v. 76, n. 9, p. 2249, doi. 10.1007/s11538-014-9997-8

By:

Fischer, Stephan;
Bernard, Samuel;
Beslon, Guillaume;
Knibbe, Carole

Publication type:

Article

Relationship between Upper Quarter Y Balance Test performance and throwing proficiency in adolescent Olympic handball players.

Published in:

BMC Sports Science, Medicine & Rehabilitation, 2020, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13102-020-00199-4

By:

Bauer, Julian;
Schedler, Simon;
Fischer, Stephan;
Muehlbauer, Thomas

Publication type:

Article

Learning single-cell chromatin accessibility profiles using meta-analytic marker genes.

Published in:

Briefings in Bioinformatics, 2023, v. 24, n. 1, p. 1, doi. 10.1093/bib/bbac541

By:

Kawaguchi, Risa Karakida;
Tang, Ziqi;
Fischer, Stephan;
Rajesh, Chandana;
Tripathy, Rohit;
Koo, Peter K;
Gillis, Jesse

Publication type:

Article

Human α-Defensin-5 Efficiently Neutralizes Clostridioides difficile Toxins TcdA, TcdB, and CDT.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.01204

By:

Korbmacher, Michael;
Fischer, Stephan;
Landenberger, Marc;
Papatheodorou, Panagiotis;
Aktories, Klaus;
Barth, Holger

Publication type:

Article

Scaling up reproducible research for single-cell transcriptomics using MetaNeighbor.

Published in:

Nature Protocols, 2021, v. 16, n. 8, p. 4031, doi. 10.1038/s41596-021-00575-5

By:

Fischer, Stephan;
Crow, Megan;
Harris, Benjamin D.;
Gillis, Jesse

Publication type:

Article

Nachruf auf Hansjörg Weitbrecht (* 4. Mai 1938 - † 10. Januar 2019).

Published in:

Industrielle Beziehungen, 2019, v. 26, n. 1, p. 120

By:

Fischer, Stephan;
Müller-Jentsch, Walther

Publication type:

Article

The Pore-Forming Subunit C2IIa of the Binary Clostridium botulinum C2 Toxin Reduces the Chemotactic Translocation of Human Polymorphonuclear Leukocytes.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.810611

By:

Eisele, Julia;
Schreiner, Simone;
Borho, Joscha;
Fischer, Stephan;
Heber, Sebastian;
Endres, Sascha;
Fellermann, Maximilian;
Wohlgemuth, Lisa;
Huber-Lang, Markus;
Fois, Giorgio;
Fauler, Michael;
Frick, Manfred;
Barth, Holger

Publication type:

Article

Inhibition of Clostridioides difficile Toxins TcdA and TcdB by Ambroxol.

Published in:

Frontiers in Pharmacology, 2022, v. 12, p. 1, doi. 10.3389/fphar.2021.809595

By:

Heber, Sebastian;
Barthold, Lara;
Baier, Jan;
Papatheodorou, Panagiotis;
Fois, Giorgio;
Frick, Manfred;
Barth, Holger;
Fischer, Stephan

Publication type:

Article

Contextual Ambidexterity: Tackling the Exploitation and Exploration Dilemma of Innovation Management in SMEs.

Published in:

International Journal of Innovation & Technology Management, 2022, v. 19, n. 2, p. 1, doi. 10.1142/S0219877022500067

By:

Reischl, Annika;
Weber, Sabrina;
Fischer, Stephan;
Lang-Koetz, Claus

Publication type:

Article

The transcriptional legacy of developmental stochasticity.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43024-5

By:

Ballouz, Sara;
Kawaguchi, Risa Karakida;
Pena, Maria T.;
Fischer, Stephan;
Crow, Megan;
French, Leon;
Knight, Frank M.;
Adams, Linda B.;
Gillis, Jesse

Publication type:

Article

The transcriptional legacy of developmental stochasticity.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43024-5

By:

Ballouz, Sara;
Kawaguchi, Risa Karakida;
Pena, Maria T.;
Fischer, Stephan;
Crow, Megan;
French, Leon;
Knight, Frank M.;
Adams, Linda B.;
Gillis, Jesse

Publication type:

Article

Assessing the replicability of spatial gene expression using atlas data from the adult mouse brain.

Published in:

PLoS Biology, 2021, v. 19, n. 7, p. 1, doi. 10.1371/journal.pbio.3001341

By:

Lu, Shaina;
Ortiz, Cantin;
Fürth, Daniel;
Fischer, Stephan;
Meletis, Konstantinos;
Zador, Anthony;
Gillis, Jesse

Publication type:

Article

Croconaine‐Based Polymer Particles as Contrast Agents for Photoacoustic Imaging.

Published in:

Macromolecular Rapid Communications, 2020, v. 41, n. 22, p. 1, doi. 10.1002/marc.202000418

By:

Jansen, Felicitas;
Lamla, Markus;
Mauthe, Diana;
Fischer, Stephan;
Barth, Holger;
Kuehne, Alexander J. C.

Publication type:

Article

Autonomous Ultrafast Self‐Healing Hydrogels by pH‐Responsive Functional Nanofiber Gelators as Cell Matrices.

Published in:

Advanced Materials, 2019, v. 31, n. 2, p. N.PAG, doi. 10.1002/adma.201805044

By:

Gačanin, Jasmina;
Hedrich, Jana;
Sieste, Stefanie;
Glaßer, Gunnar;
Lieberwirth, Ingo;
Schilling, Corinna;
Fischer, Stephan;
Barth, Holger;
Knöll, Bernd;
Synatschke, Christopher V.;
Weil, Tanja

Publication type:

Article

In situ monitoring of Lentilactobacillus parabuchneri biofilm formation via real-time infrared spectroscopy.

Published in:

NPJ Biofilms & Microbiomes, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41522-022-00353-5

By:

Bajrami, Diellza;
Fischer, Stephan;
Barth, Holger;
Sarquis, María A.;
Ladero, Victor M.;
Fernández, María;
Sportelli, Maria. C.;
Cioffi, Nicola;
Kranz, Christine;
Mizaikoff, Boris

Publication type:

Article

An antibody to IL-1 receptor 7 protects mice from LPS-induced tissue and systemic inflammation.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1427100

By:

Liqiong Jiang;
Lunding, Lars P.;
Webber, William S.;
Beckmann, Karsten;
Azam, Tania;
Højen, Jesper Falkesgaard;
Amo-Aparicio, Jesus;
Dinarello, Alberto;
Nguyen, Tom T.;
Pessara, Ulrich;
Parera, Daniel;
Orlicky, David J.;
Fischer, Stephan;
Wegmann, Michael;
Dinarello, Charles A.;
Suzhao Li

Publication type:

Article

The bacterial interlocked process ONtology (BiPON): a systemic multi-scale unified representation of biological processes in prokaryotes.

Published in:

Journal of Biomedical Semantics, 2017, v. 8, p. 1, doi. 10.1186/s13326-017-0165-6

By:

Henry, Vincent J.;
Goelzer, Anne;
Ferré, Arnaud;
Fischer, Stephan;
Dinh, Marc;
Loux, Valentin;
Froidevaux, Christine;
Fromion, Vincent

Publication type:

Article

Clostridium botulinum C3 Toxin for Selective Delivery of Cargo into Dendritic Cells and Macrophages.

Published in:

Toxins, 2022, v. 14, n. 10, p. N.PAG, doi. 10.3390/toxins14100711

By:

Fellermann, Maximilian;
Stemmer, Mia;
Noschka, Reiner;
Wondany, Fanny;
Fischer, Stephan;
Michaelis, Jens;
Stenger, Steffen;
Barth, Holger

Publication type:

Article

In silico experimental evolution: a tool to test evolutionary scenarios.

Published in:

BMC Bioinformatics, 2013, v. 14, n. Suppl 15, p. 1, doi. 10.1186/1471-2105-14-s15-s11

By:

Batut, Bérénice;
Parsons, David P.;
Fischer, Stephan;
Beslon, Guillaume;
Knibbe, Carole

Publication type:

Article

Fcγ-Receptor-Independent Controlled Activation of CD40 Canonical Signaling by Novel Therapeutic Antibodies for Cancer Therapy.

Published in:

Antibodies (2073-4468), 2024, v. 13, n. 2, p. 31, doi. 10.3390/antib13020031

By:

Beckmann, Karsten;
Reitinger, Carmen;
Yan, Xianglei;
Carle, Anna;
Blümle, Eva;
Jurkschat, Nicole;
Paulmann, Claudia;
Prassl, Sandra;
Kazandjian, Linda V.;
Loré, Karin;
Nimmerjahn, Falk;
Fischer, Stephan

Publication type:

Article

Nitrile Ylides and Azirines: Gas-Phase Generation from 2,3-Dihydro-1,4,λ<sup>5</sup>-oxazaphospholes and Matrix Isolation.

Published in:

Angewandte Chemie International Edition, 1986, v. 25, n. 1, p. 85, doi. 10.1002/anie.198600851

By:

Wentrup, Curt;
Fischer, Stephan;
Berstermann, Hans-Michael;
Kuzaj, Martin;
Lüerssen, Holger;
Burger, Klaus

Publication type:

Article

Nitrile Imines: Thermal Generation, Direct Observation, and Subsequent Trapping.

Published in:

Angewandte Chemie International Edition, 1985, v. 24, n. 1, p. 56, doi. 10.1002/anie.198500561

By:

Wentrup, Curt;
Fischer, Stephan;
Maquestiau, André;
Flammang, Robert

Publication type:

Article

Human Serum Albumin Is an Essential Component of the Host Defense Mechanism Against Clostridium difficile Intoxication.

Published in:

2018

By:

Masi, Alessandra di;
Leboffe, Loris;
Polticelli, Fabio;
Tonon, Federica;
Zennaro, Cristina;
Caterino, Marianna;
Stano, Pasquale;
Fischer, Stephan;
Hägele, Marlen;
Müller, Martin;
di Masi, Alessandra;
Kleger, Alexander;
Papatheodorou, Panagiotis;
Nocca, Giuseppina;
Arcovito, Alessandro;
Gori, Andrea;
Ruoppolo, Margherita;
Barth, Holger;
Petrosillo, Nicola;
Ascenzi, Paolo

Publication type:

journal article

Human peptide α‐defensin‐1 interferes with Clostridioides difficile toxins TcdA, TcdB, and CDT.

Published in:

FASEB Journal, 2020, v. 34, n. 5, p. 6244, doi. 10.1096/fj.201902816R

By:

Fischer, Stephan;
Ückert, Anna‐Katharina;
Landenberger, Marc;
Papatheodorou, Panagiotis;
Hoffmann‐Richter, Carola;
Mittler, Ann‐Katrin;
Ziener, Ulrich;
Hägele, Marlen;
Schwan, Carsten;
Müller, Martin;
Kleger, Alexander;
Benz, Roland;
Popoff, Michel R.;
Aktories, Klaus;
Barth, Holger

Publication type:

Article

Closing two doors of viral entry: Intramolecular combination of a coreceptor- and fusion inhibitor of HIV-1.

Published in:

Virology Journal, 2008, v. 5, p. 1, doi. 10.1186/1743-422X-5-56

By:

Kopetzki, Erhard;
Jekle, Andreas;
Changhua Ji;
Rao, Eileen;
Zhang, Jun;
Fischer, Stephan;
Cammack, Nick;
Sankuratri, Surya;
Heilek, Gabrielle

Publication type:

Article

Boosting Antitumor Drug Efficacy with Chemically Engineered Multidomain Proteins.

Published in:

Advanced Science, 2018, v. 5, n. 8, p. 1, doi. 10.1002/advs.201701036

By:

Kuan, Seah Ling;
Fischer, Stephan;
Hafner, Susanne;
Wang, Tao;
Syrovets, Tatiana;
Liu, Weina;
Tokura, Yu;
Ng, David Yuen Wah;
Riegger, Andreas;
Förtsch, Christina;
Jäger, Daniela;
Barth, Thomas F. E.;
Simmet, Thomas;
Barth, Holger;
Weil, Tanja

Publication type:

Article

Targeted Protein Delivery: Supramolecular Toxin Complexes for Targeted Pharmacological Modulation of Polymorphonuclear Leukocyte Functions (Adv. Healthcare Mater. 17/2019).

Published in:

Advanced Healthcare Materials, 2019, v. 8, n. 17, p. N.PAG, doi. 10.1002/adhm.201970072

By:

Heck, Astrid Johanna;
Ostertag, Theresa;
Schnell, Leonie;
Fischer, Stephan;
Agrawalla, Bikram Keshari;
Winterwerber, Pia;
Wirsching, Eva;
Fauler, Michael;
Frick, Manfred;
Kuan, Seah Ling;
Weil, Tanja;
Barth, Holger

Publication type:

Article

Supramolecular Toxin Complexes for Targeted Pharmacological Modulation of Polymorphonuclear Leukocyte Functions.

Published in:

Advanced Healthcare Materials, 2019, v. 8, n. 17, p. N.PAG, doi. 10.1002/adhm.201900665

By:

Heck, Astrid Johanna;
Ostertag, Theresa;
Schnell, Leonie;
Fischer, Stephan;
Agrawalla, Bikram Keshari;
Winterwerber, Pia;
Wirsching, Eva;
Fauler, Michael;
Frick, Manfred;
Kuan, Seah Ling;
Weil, Tanja;
Barth, Holger

Publication type:

Article

Spatiotemporally Controlled Release of Rho-Inhibiting C3 Toxin from a Protein-DNA Hybrid Hydrogel for Targeted Inhibition of Osteoclast Formation and Activity.

Published in:

Advanced Healthcare Materials, 2017, v. 6, n. 21, p. n/a, doi. 10.1002/adhm.201700392

By:

Gačanin, Jasmina;
Kovtun, Anna;
Fischer, Stephan;
Schwager, Victoria;
Quambusch, Johanna;
Kuan, Seah Ling;
Liu, Weina;
Boldt, Felix;
Li, Chuang;
Yang, Zhongqiang;
Liu, Dongsheng;
Wu, Yuzhou;
Weil, Tanja;
Barth, Holger;
Ignatius, Anita

Publication type:

Article

Clostridial C3 Toxins Enter and Intoxicate Human Dendritic Cells.

Published in:

Toxins, 2020, v. 12, n. 9, p. 563, doi. 10.3390/toxins12090563

By:

Fellermann, Maximilian;
Huchler, Christina;
Fechter, Lea;
Kolb, Tobias;
Wondany, Fanny;
Mayer, Daniel;
Michaelis, Jens;
Stenger, Steffen;
Mellert, Kevin;
Möller, Peter;
Barth, Thomas F. E.;
Fischer, Stephan;
Barth, Holger

Publication type:

Article

BiPSim: a flexible and generic stochastic simulator for polymerization processes.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-92833-5

By:

Fischer, Stephan;
Dinh, Marc;
Henry, Vincent;
Robert, Philippe;
Goelzer, Anne;
Fromion, Vincent

Publication type:

Article

A novel rabbit derived anti-HER2 antibody with pronounced therapeutic effectiveness on HER2-positive breast cancer cells in vitro and in humanized tumor mice (HTM).

Published in:

2020

By:

Wege, Anja Kathrin;
Kirchhammer, Nicole;
Kazandjian, Linda Veronique;
Prassl, Sandra;
Brandt, Michael;
Piendl, Gerhard;
Ortmann, Olaf;
Fischer, Stephan;
Brockhoff, Gero

Publication type:

journal article

Improving replicability in single-cell RNA-Seq cell type discovery with Dune.

Published in:

BMC Bioinformatics, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12859-024-05814-6

By:

Roux de Bézieux, Hector;
Street, Kelly;
Fischer, Stephan;
Van den Berge, Koen;
Chance, Rebecca;
Risso, Davide;
Gillis, Jesse;
Ngai, John;
Purdom, Elizabeth;
Dudoit, Sandrine

Publication type:

Article

Antimicrobial Efficiency of Chitosan and Its Methylated Derivative against Lentilactobacillus parabuchneri Biofilms.

Published in:

Molecules, 2022, v. 27, n. 24, p. 8647, doi. 10.3390/molecules27248647

By:

Bajrami, Diellza;
Fischer, Stephan;
Barth, Holger;
Hossain, Syed Imdadul;
Cioffi, Nicola;
Mizaikoff, Boris

Publication type:

Article

Cell targeting and immunostimulatory properties of a novel Fcγ-receptor-independent agonistic anti-CD40 antibody in rhesus macaques.

Published in:

Cellular & Molecular Life Sciences, 2023, v. 80, n. 7, p. 1, doi. 10.1007/s00018-023-04828-2

By:

Yan, Xianglei;
Ols, Sebastian;
Arcoverde Cerveira, Rodrigo;
Lenart, Klara;
Hellgren, Fredrika;
Ye, Kewei;
Cagigi, Alberto;
Buggert, Marcus;
Nimmerjahn, Falk;
Falkesgaard Højen, Jesper;
Parera, Daniel;
Pessara, Ulrich;
Fischer, Stephan;
Loré, Karin

Publication type:

Article