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Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment.
Published in:
Nature Communications, 2023, n. 1, p. 1, doi. 10.1038/s41467-023-39817-3
By:
- Haake, Markus;
- Haack, Beatrice;
- Schäfer, Tina;
- Harter, Patrick N.;
- Mattavelli, Greta;
- Eiring, Patrick;
- Vashist, Neha;
- Wedekink, Florian;
- Genssler, Sabrina;
- Fischer, Birgitt;
- Dahlhoff, Julia;
- Mokhtari, Fatemeh;
- Kuzkina, Anastasia;
- Welters, Marij J. P.;
- Benz, Tamara M.;
- Sorger, Lena;
- Thiemann, Vincent;
- Almanzar, Giovanni;
- Selle, Martina;
- Thein, Klara
Publication type:
Article
Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity.
Published in:
Cancer Immunology, Immunotherapy, 2011, v. 60, n. 10, p. 1405, doi. 10.1007/s00262-011-1040-4
By:
- Häusler, Sebastian;
- Montalbán del Barrio, Itsaso;
- Strohschein, Jenny;
- Anoop Chandran, P.;
- Engel, Jörg;
- Hönig, Arnd;
- Ossadnik, Monika;
- Horn, Evi;
- Fischer, Birgitt;
- Krockenberger, Mathias;
- Heuer, Stefan;
- Seida, Ahmed;
- Junker, Markus;
- Kneitz, Hermann;
- Kloor, Doris;
- Klotz, Karl-Norbert;
- Dietl, Johannes;
- Wischhusen, Jörg
Publication type:
Article