Found: 14

Select item for more details and to access through your institution.

  • A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41240-7
    By:
    • Bestas, Burcu;
    • Wimberger, Sandra;
    • Degtev, Dmitrii;
    • Madsen, Alexandra;
    • Rottner, Antje K.;
    • Karlsson, Fredrik;
    • Naumenko, Sergey;
    • Callahan, Megan;
    • Touza, Julia Liz;
    • Francescatto, Margherita;
    • Möller, Carl Ivar;
    • Badertscher, Lukas;
    • Li, Songyuan;
    • Cerboni, Silvia;
    • Selfjord, Niklas;
    • Ericson, Elke;
    • Gordon, Euan;
    • Firth, Mike;
    • Chylinski, Krzysztof;
    • Taheri-Ghahfarokhi, Amir
    Publication type:
    Article

  • Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40344-4
    By:
    • Wimberger, Sandra;
    • Akrap, Nina;
    • Firth, Mike;
    • Brengdahl, Johan;
    • Engberg, Susanna;
    • Schwinn, Marie K.;
    • Slater, Michael R.;
    • Lundin, Anders;
    • Hsieh, Pei-Pei;
    • Li, Songyuan;
    • Cerboni, Silvia;
    • Sumner, Jonathan;
    • Bestas, Burcu;
    • Schiffthaler, Bastian;
    • Magnusson, Björn;
    • Di Castro, Silvio;
    • Iyer, Preeti;
    • Bohlooly-Y, Mohammad;
    • Machleidt, Thomas;
    • Rees, Steve
    Publication type:
    Article

  • An incremental, exploratory and transformational environment for lazy functional programming.

    Published in:
    Journal of Functional Programming, 1993, v. 3, n. 1, p. 93, doi. 10.1017/S0956796800000629
    By:
    • Runciman, Colin;
    • Toyn, Ian;
    • Firth, Mike
    Publication type:
    Article

  • Engineered Cas9 extracellular vesicles as a novel gene editing tool.

    Published in:
    Journal of Extracellular Vesicles, 2022, v. 11, n. 5, p. 1, doi. 10.1002/jev2.12225
    By:
    • Osteikoetxea, Xabier;
    • Silva, Andreia;
    • Lázaro‐Ibáñez, Elisa;
    • Salmond, Nikki;
    • Shatnyeva, Olga;
    • Stein, Josia;
    • Schick, Jan;
    • Wren, Stephen;
    • Lindgren, Julia;
    • Firth, Mike;
    • Madsen, Alexandra;
    • Mayr, Lorenz M.;
    • Overman, Ross;
    • Davies, Rick;
    • Dekker, Niek
    Publication type:
    Article

  • Author Correction: Universal toxin-based selection for precise genome engineering in human cells.

    Published in:
    2021
    By:
    • Li, Songyuan;
    • Akrap, Nina;
    • Cerboni, Silvia;
    • Porritt, Michelle J.;
    • Wimberger, Sandra;
    • Lundin, Anders;
    • Möller, Carl;
    • Firth, Mike;
    • Gordon, Euan;
    • Lazovic, Bojana;
    • Sieńska, Aleksandra;
    • Pane, Luna Simona;
    • Coelho, Matthew A.;
    • Ciotta, Giovanni;
    • Pellegrini, Giovanni;
    • Sini, Marcella;
    • Xu, Xiufeng;
    • Mitra, Suman;
    • Bohlooly-Y, Mohammad;
    • Taylor, Benjamin J. M.
    Publication type:
    Correction Notice

  • Universal toxin-based selection for precise genome engineering in human cells.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20810-z
    By:
    • Li, Songyuan;
    • Akrap, Nina;
    • Cerboni, Silvia;
    • Porritt, Michelle J.;
    • Wimberger, Sandra;
    • Lundin, Anders;
    • Möller, Carl;
    • Firth, Mike;
    • Gordon, Euan;
    • Lazovic, Bojana;
    • Sieńska, Aleksandra;
    • Pane, Luna Simona;
    • Coelho, Matthew A.;
    • Ciotta, Giovanni;
    • Pellegrini, Giovanni;
    • Sini, Marcella;
    • Xu, Xiufeng;
    • Mitra, Suman;
    • Bohlooly-Y, Mohammad;
    • Taylor, Benjamin J. M.
    Publication type:
    Article

  • Universal toxin-based selection for precise genome engineering in human cells.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20810-z
    By:
    • Li, Songyuan;
    • Akrap, Nina;
    • Cerboni, Silvia;
    • Porritt, Michelle J.;
    • Wimberger, Sandra;
    • Lundin, Anders;
    • Möller, Carl;
    • Firth, Mike;
    • Gordon, Euan;
    • Lazovic, Bojana;
    • Sieńska, Aleksandra;
    • Pane, Luna Simona;
    • Coelho, Matthew A.;
    • Ciotta, Giovanni;
    • Pellegrini, Giovanni;
    • Sini, Marcella;
    • Xu, Xiufeng;
    • Mitra, Suman;
    • Bohlooly-Y, Mohammad;
    • Taylor, Benjamin J. M.
    Publication type:
    Article

  • CRISPR GUARD protects off-target sites from Cas9 nuclease activity using short guide RNAs.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-17952-5
    By:
    • Coelho, Matthew A.;
    • De Braekeleer, Etienne;
    • Firth, Mike;
    • Bista, Michal;
    • Lukasiak, Sebastian;
    • Cuomo, Maria Emanuela;
    • Taylor, Benjamin J. M.
    Publication type:
    Article

  • Harnessing DSB repair to promote efficient homology-dependent and -independent prime editing.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28771-1
    By:
    • Peterka, Martin;
    • Akrap, Nina;
    • Li, Songyuan;
    • Wimberger, Sandra;
    • Hsieh, Pei-Pei;
    • Degtev, Dmitrii;
    • Bestas, Burcu;
    • Barr, Jack;
    • van de Plassche, Stijn;
    • Mendoza-Garcia, Patricia;
    • Šviković, Saša;
    • Sienski, Grzegorz;
    • Firth, Mike;
    • Maresca, Marcello
    Publication type:
    Article

  • Rapid target validation in a Cas9-inducible hiPSC derived kidney model.

    Published in:
    Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-95986-5
    By:
    • Shamshirgaran, Yasaman;
    • Jonebring, Anna;
    • Svensson, Anna;
    • Leefa, Isabelle;
    • Bohlooly-Y, Mohammad;
    • Firth, Mike;
    • Woollard, Kevin J.;
    • Hofherr, Alexis;
    • Rogers, Ian M.;
    • Hicks, Ryan
    Publication type:
    Article

  • Epigenetic modulators link mitochondrial redox homeostasis to cardiac function in a sex-dependent manner.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46384-8
    By:
    • ElBeck, Zaher;
    • Hossain, Mohammad Bakhtiar;
    • Siga, Humam;
    • Oskolkov, Nikolay;
    • Karlsson, Fredrik;
    • Lindgren, Julia;
    • Walentinsson, Anna;
    • Koppenhöfer, Dominique;
    • Jarvis, Rebecca;
    • Bürli, Roland;
    • Jamier, Tanguy;
    • Franssen, Elske;
    • Firth, Mike;
    • Degasperi, Andrea;
    • Bendtsen, Claus;
    • Menzies, Robert I.;
    • Streckfuss-Bömeke, Katrin;
    • Kohlhaas, Michael;
    • Nickel, Alexander G.;
    • Lund, Lars H.
    Publication type:
    Article

  • Orthologue chemical space and its influence on target prediction.

    Published in:
    Bioinformatics, 2018, v. 34, n. 1, p. 72, doi. 10.1093/bioinformatics/btx525
    By:
    • Mervin, Lewis H;
    • Bulusu, Krishna C;
    • Kalash, Leen;
    • Afzal, Avid M;
    • Svensson, Fredrik;
    • Firth, Mike A;
    • Barrett, Ian;
    • Engkvist, Ola;
    • Bender, Andreas
    Publication type:
    Article

  • BE-FLARE: a fluorescent reporter of base editing activity reveals editing characteristics of APOBEC3A and APOBEC3B.

    Published in:
    BMC Biology, 2018, v. 16, n. 1, p. 1, doi. 10.1186/s12915-018-0617-1
    By:
    • Coelho, Matthew A.;
    • Li, Songyuan;
    • Pane, Luna Simona;
    • Firth, Mike;
    • Ciotta, Giovanni;
    • Wrigley, Jonathan D.;
    • Cuomo, Maria Emanuela;
    • Maresca, Marcello;
    • Taylor, Benjamin J. M.
    Publication type:
    Article

  • In vivo phage display identifies novel peptides for cardiac targeting.

    Published in:
    Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-62953-9
    By:
    • Ivanova, Alena;
    • Kohl, Franziska;
    • González-King Garibotti, Hernán;
    • Chalupska, Renata;
    • Cvjetkovic, Aleksander;
    • Firth, Mike;
    • Jennbacken, Karin;
    • Martinsson, Sofia;
    • Silva, Andreia M.;
    • Viken, Ida;
    • Wang, Qing-Dong;
    • Wiseman, John;
    • Dekker, Niek
    Publication type:
    Article