Works matching AU Finotti, Alessia
Results: 83
Constitutive systemic inflammation in Shwachman-Diamond Syndrome.
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- Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01133-5
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- Article
Perspectives in MicroRNA Therapeutics for Cystic Fibrosis.
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- Non-Coding RNA, 2025, v. 11, n. 1, p. 3, doi. 10.3390/ncrna11010003
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- Article
Development of K562 cell clones expressing β-globin mRNA carrying the β039 thalassaemia mutation for the screening of correctors of stop-codon mutations.
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- Biotechnology & Applied Biochemistry, 2009, v. 54, n. 1, p. 41, doi. 10.1042/BA20080266
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- Article
A Novel Frameshift Mutation (+A) at Codon 18 of the β-Globin Gene Associated with High Persistence of Fetal Hemoglobin Phenotype and δβ-Thalassemia.
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- Acta Haematologica, 2008, v. 119, n. 1, p. 28, doi. 10.1159/000114204
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- Article
Demonstrating specificity of bioactive peptide nucleic acids (PNAs) targeting microRNAs for practical laboratory classes of applied biochemistry and pharmacology.
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- PLoS ONE, 2019, v. 14, n. 9, p. 1, doi. 10.1371/journal.pone.0221923
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- Article
MicroRNA miR-93-5p regulates expression of IL-8 and VEGF in neuroblastoma SK-N-AS cells.
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- Oncology Reports, 2016, v. 35, n. 5, p. 2866, doi. 10.3892/or.2016.4676
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- Article
A β-Thalassemia Cell Biobank: Updates, Further Validation in Genetic and Therapeutic Research and Opportunities During (and After) the COVID-19 Pandemic.
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- Journal of Clinical Medicine, 2025, v. 14, n. 1, p. 289, doi. 10.3390/jcm14010289
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- Article
Increased Expression of α-Hemoglobin Stabilizing Protein (AHSP) mRNA in Erythroid Precursor Cells Isolated from β-Thalassemia Patients Treated with Sirolimus (Rapamycin).
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- Journal of Clinical Medicine, 2024, v. 13, n. 9, p. 2479, doi. 10.3390/jcm13092479
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- Article
A Peptide-Nucleic Acid Targeting miR-335-5p Enhances Expression of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene with the Possible Involvement of the CFTR Scaffolding Protein NHERF1.
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- Biomedicines, 2021, v. 9, n. 2, p. 117, doi. 10.3390/biomedicines9020117
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- Article
Efficient cell penetration and delivery of peptide nucleic acids by an argininocalix[4]arene.
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- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-39211-4
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- Article
Effects of Sirolimus Treatment on Fetal Hemoglobin Production and Response to SARS-CoV-2 Vaccination: A Case Report Study.
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- 2023
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- Case Study
Changes in hemoglobin profile reflect autologous blood transfusion misuse in sports.
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- 2018
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- Publication type:
- journal article
Expression of microRNA-93 and Interleukin-8 during Pseudomonas aeruginosa-Mediated Induction of Proinflammatory Responses.
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- American Journal of Respiratory Cell & Molecular Biology, 2014, v. 50, n. 6, p. 1144, doi. 10.1165/rcmb.2013-0160OC
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- Article
Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters.
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- Analytical & Bioanalytical Chemistry, 2019, v. 411, n. 29, p. 7669, doi. 10.1007/s00216-019-01959-z
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- Article
Surface plasmon resonance based analysis of the binding of LYAR protein to the rs368698783 (G>A) polymorphic Aγ-globin gene sequences mutated in β-thalassemia.
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- Analytical & Bioanalytical Chemistry, 2019, v. 411, n. 29, p. 7699, doi. 10.1007/s00216-019-01987-9
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- Article
Therapeutic Relevance of Inducing Autophagy in β-Thalassemia.
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- Cells (2073-4409), 2024, v. 13, n. 11, p. 918, doi. 10.3390/cells13110918
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- Article
Enzymatic Spermine Metabolites Induce Apoptosis Associated with Increase of p53, caspase-3 and miR-34a in Both Neuroblastoma Cells, SJNKP and the N-Myc-Amplified Form IMR5.
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- Cells (2073-4409), 2021, v. 10, n. 8, p. 1950, doi. 10.3390/cells10081950
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- Article
Targeting DNA Binding for NF-κB as an Anticancer Approach in Hepatocellular Carcinoma.
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- Cells (2073-4409), 2018, v. 7, n. 10, p. 177, doi. 10.3390/cells7100177
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- Article
Expression of γ-globin genes in β-thalassemia patients treated with sirolimus: results from a pilot clinical trial (Sirthalaclin).
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- Therapeutic Advances in Hematology, 2022, v. 13, p. 1, doi. 10.1177/20406207221100648
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- Article
Effects of Mithramycin on BCL11A Gene Expression and on the Interaction of the BCL11A Transcriptional Complex to γ-Globin Gene Promoter Sequences.
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- Genes, 2023, v. 14, n. 10, p. 1927, doi. 10.3390/genes14101927
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- Article
Production and Characterization of K562 Cellular Clones Hyper-Expressing the Gene Encoding α-Globin: Preliminary Analysis of Biomarkers Associated with Autophagy.
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- Genes, 2023, v. 14, n. 3, p. 556, doi. 10.3390/genes14030556
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- Article
Co-Treatment of Erythroid Cells from β-Thalassemia Patients with CRISPR-Cas9-Based β 0 39-Globin Gene Editing and Induction of Fetal Hemoglobin.
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- Genes, 2022, v. 13, n. 10, p. N.PAG, doi. 10.3390/genes13101727
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- Article
Effects of Sirolimus treatment on patients with β‐Thalassemia: Lymphocyte immunophenotype and biological activity of memory CD4<sup>+</sup> and CD8<sup>+</sup> T cells.
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- Journal of Cellular & Molecular Medicine, 2023, v. 27, n. 3, p. 353, doi. 10.1111/jcmm.17655
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- Article
Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β -Globin Gene with the IVSI-6 Thalassemia Mutation.
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- BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/687635
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- Article
Recent trends in the gene therapy of β-thalassemia.
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- Journal of Blood Medicine, 2015, v. 6, p. 69, doi. 10.2147/JBM.S46256
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- Article
Chemical-Induced Read-Through at Premature Termination Codons Determined by a Rapid Dual-Fluorescence System Based on S. cerevisiae.
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- PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0154260
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- Article
Increase of microRNA-210, Decrease of Raptor Gene Expression and Alteration of Mammalian Target of Rapamycin Regulated Proteins following Mithramycin Treatment of Human Erythroid Cells.
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- PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0121567
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- Article
Differential Effects of Angelicin Analogues on NF-κB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells.
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- Mediators of Inflammation, 2017, p. 1, doi. 10.1155/2017/2389487
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- Article
Transient Receptor Potential Ankyrin 1 Channels Modulate Inflammatory Response in Respiratory Cells from Patients with Cystic Fibrosis.
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- American Journal of Respiratory Cell & Molecular Biology, 2016, v. 55, n. 5, p. 645, doi. 10.1165/rcmb.2016-0089OC
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- Article
Regulation of IL-8 gene expression in gliomas by microRNA miR-93.
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- 2015
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- Publication type:
- journal article
Synergistic effects of the combined treatment of U251 and T98G glioma cells with an anti-tubulin tetrahydrothieno[2,3-c]pyridine derivative and a peptide nucleic acid targeting miR-221-3p.
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- International Journal of Oncology, 2021, v. 59, n. 2, p. N.PAG, doi. 10.3892/ijo.2021.5241
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- Article
Targeting miR-155-5p and miR-221-3p by peptide nucleic acids induces caspase-3 activation and apoptosis in temozolomide-resistant T98G glioma cells.
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- International Journal of Oncology, 2019, v. 55, n. 1, p. 59, doi. 10.3892/ijo.2019.4810
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- Article
Liquid biopsy and PCR-free ultrasensitive detection systems in oncology (Review).
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- International Journal of Oncology, 2018, v. 53, n. 4, p. 1395, doi. 10.3892/ijo.2018.4516
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- Article
High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222.
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- International Journal of Oncology, 2016, v. 48, n. 3, p. 1029, doi. 10.3892/ijo.2015.3308
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- Article
Pro-apoptotic activity of novel synthetic isoxazole derivatives exhibiting inhibitory activity against tumor cell growth in vitro.
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- Oncology Letters, 2020, v. 20, n. 5, p. 1, doi. 10.3892/ol.2020.12002
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- Article
The Long Scientific Journey of Sirolimus (Rapamycin): From the Soil of Easter Island (Rapa Nui) to Applied Research and Clinical Trials on β-Thalassemia and Other Hemoglobinopathies.
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- Biology (2079-7737), 2023, v. 12, n. 9, p. 1202, doi. 10.3390/biology12091202
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- Article
Complexation to Cationic Microspheres of Double-Stranded Peptide Nucleic Acid-DNA Chimeras Exhibiting Decoy Activity.
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- Journal of Biomedical Science, 2004, v. 11, n. 5, p. 697, doi. 10.1007/BF02256136
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- Article
Corilagin Induces High Levels of Apoptosis in the Temozolomide-Resistant T98G Glioma Cell Line.
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- Oncology Research, 2018, v. 26, n. 9, p. 1307, doi. 10.3727/096504017X14928634401187
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- Article
Uptake by human glioma cell lines and biological effects of a peptide-nucleic acids targeting miR-221.
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- Journal of Neuro-Oncology, 2014, v. 118, n. 1, p. 19, doi. 10.1007/s11060-014-1405-6
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- Publication type:
- Article
Production of β-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous β<sup>0</sup>39 thalassemia patients.
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- American Journal of Hematology, 2009, v. 84, n. 11, p. 720, doi. 10.1002/ajh.21539
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- Publication type:
- Article
The Cystic Fibrosis Transmembrane Conductance Regulator Gene (CFTR) Is under Post-Transcriptional Control of microRNAs: Analysis of the Effects of agomiRNAs Mimicking miR-145-5p, miR-101-3p, and miR-335-5p.
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- Non-Coding RNA, 2023, v. 9, n. 2, p. 29, doi. 10.3390/ncrna9020029
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- Article
Role of Cystic Fibrosis Bronchial Epithelium in Neutrophil Chemotaxis.
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- Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.01438
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- Publication type:
- Article
Effects of rapamycin on accumulation of α-, β- and γ-globin mRNAs in erythroid precursor cells from β-thalassaemia patients.
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- European Journal of Haematology, 2006, v. 77, n. 5, p. 437, doi. 10.1111/j.1600-0609.2006.00731.x
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- Article
Liquid biopsy in mice bearing colorectal carcinoma xenografts: gateways regulating the levels of circulating tumor DNA (ctDNA) and miRNA (ctmiRNA).
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- Journal of Experimental & Clinical Cancer Research (17569966), 2018, v. 37, n. 1, p. N.PAG, doi. 10.1186/s13046-018-0788-1
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- Article
Modulation of the Biological Activity of microRNA-210 with Peptide Nucleic Acids (PNAs).
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- ChemMedChem, 2011, v. 6, n. 12, p. 2192, doi. 10.1002/cmdc.201100270
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- Article
Increase in gamma-globin mRNA content in human erythroid cells treated with angelicin analogs.
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- 2009
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- Publication type:
- journal article
Impact of α-Globin Gene Expression and α-Globin Modifiers on the Phenotype of β-Thalassemia and Other Hemoglobinopathies: Implications for Patient Management.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 6, p. 3400, doi. 10.3390/ijms25063400
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- Publication type:
- Article
Decrease in α-Globin and Increase in the Autophagy-Activating Kinase ULK1 mRNA in Erythroid Precursors from β-Thalassemia Patients Treated with Sirolimus.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 20, p. 15049, doi. 10.3390/ijms242015049
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- Article
The rs368698783 (G>A) Polymorphism Affecting LYAR Binding to the Aγ-Globin Gene Is Associated with High Fetal Hemoglobin (HbF) in β-Thalassemia Erythroid Precursor Cells Treated with HbF Inducers.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 776, doi. 10.3390/ijms24010776
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- Publication type:
- Article
Combined Treatment of Bronchial Epithelial Calu-3 Cells with Peptide Nucleic Acids Targeting miR-145-5p and miR-101-3p: Synergistic Enhancement of the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 16, p. 9348, doi. 10.3390/ijms23169348
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- Publication type:
- Article