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AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12836-9
By:
- Fok, Jacqueline H. L.;
- Ramos-Montoya, Antonio;
- Vazquez-Chantada, Mercedes;
- Wijnhoven, Paul W. G.;
- Follia, Valeria;
- James, Neil;
- Farrington, Paul M.;
- Karmokar, Ankur;
- Willis, Sophie E.;
- Cairns, Jonathan;
- Nikkilä, Jenni;
- Beattie, David;
- Lamont, Gillian M.;
- Finlay, M. Raymond V.;
- Wilson, Joanne;
- Smith, Aaron;
- O'Connor, Lenka Oplustil;
- Ling, Stephanie;
- Fawell, Stephen E.;
- O'Connor, Mark J.
Publication type:
Article
Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy.
Published in:
2020
By:
- Willoughby, Catherine E.;
- Yanyan Jiang;
- Thomas, Huw D.;
- Willmore, Elaine;
- Kyle, Suzanne;
- Wittner, Anita;
- Phillips, Nicole;
- Yan Zhao;
- Tudhope, Susan J.;
- Prendergast, Lisa;
- Junge, Gesa;
- Lourenco, Luiza Madia;
- Finlay, M. Raymond V.;
- Turner, Paul;
- Munck, Joanne M.;
- Griffin, Roger J.;
- Rennison, Tommy;
- Pickles, James;
- Cano, Celine;
- Newell, David R.
Publication type:
journal article
Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy.
Published in:
Journal of Clinical Investigation, 2020, v. 130, n. 1, p. 258, doi. 10.1172/JCI127483
By:
- Willoughby, Catherine E.;
- Yanyan Jiang;
- Thomas, Huw D.;
- Willmore, Elaine;
- Kyle, Suzanne;
- Wittner, Anita;
- Phillips, Nicole;
- Yan Zhao;
- Tudhope, Susan J.;
- Prendergast, Lisa;
- Junge, Gesa;
- Lourenco, Luiza Madia;
- Finlay, M. Raymond V.;
- Turner, Paul;
- Munck, Joanne M.;
- Griffin, Roger J.;
- Rennison, Tommy;
- Pickles, James;
- Cano, Celine;
- Newell, David R.
Publication type:
Article
Antitumor efficacy of 26-fluoroepothilone B against human prostate cancer xenografts.
Published in:
2001
By:
- Newman, Robert A.;
- Yang, Jun;
- Finlay, M. Raymond V.;
- Cabral, Fernando;
- Vourloumis, Dionisios;
- Stephens, L.Clifton;
- Troncoso, Patricia;
- Wu, Xiaobing;
- Logothetis, Christopher J.;
- Nicolaou, K.C.;
- Navone, Nora M.;
- Newman, R A;
- Yang, J;
- Raymond, M;
- Finlay, V;
- Cabral, F;
- Vourloumis, D;
- Stephens, L C;
- Troncoso, P;
- Wu, X
Publication type:
journal article
Total Synthesis of 16-Desmethylepothilone B, Epothilone B<sub>10</sub>, Epothilone F, and Related Side Chain Modified Epothilone B Analogues.
Published in:
Chemistry - A European Journal, 2000, v. 6, n. 15, p. 2783, doi. 10.1002/1521-3765(20000804)6:15<2783::AID-CHEM2783>3.0.CO;2-B
By:
- Nicolaou, K. C.;
- Hepworth, David;
- King, N. Paul;
- Finlay, M. Raymond V.;
- Scarpelli, Rita;
- Pereira, M. Manuela A.;
- Bollbuck, Birgit;
- Bigot, Antony;
- Werschkun, Barbara;
- Winssinger, Nicolas
Publication type:
Article

Found: 5

AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity.

Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy.

Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy.

Antitumor efficacy of 26-fluoroepothilone B against human prostate cancer xenografts.

Total Synthesis of 16-Desmethylepothilone B, Epothilone B<sub>10</sub>, Epothilone F, and Related Side Chain Modified Epothilone B Analogues.