Works by Finel, Moshe

Results: 26

High-throughput screening technologies for drug glucuronidation profiling.

Published in:

Journal of Pharmacy & Pharmacology, 2008, v. 60, n. 8, p. 1061, doi. 10.1211/jpp.60.8.0012

By:

Olga Trubetskoy;
Moshe Finel;
Vladimir Trubetskoy

Publication type:

Article

Mutation analysis in UGT1A9 suggests a relationship between substrate and catalytic residues in UDP-glucuronosyltransferases.

Published in:

PEDS: Protein Engineering, Design & Selection, 2008, v. 21, n. 9, p. 537, doi. 10.1093/protein/gzn030

By:

Anne-Sisko Patana;
Mika Kurkela;
Moshe Finel;
Adrian Goldman

Publication type:

Article

Aspartic Acid393 of the DxxD Motif within The C-Terminal Region of Human UDP-Glucuronosyltransferase 1A10 is Critical to the Binding of UDP-Glucuronic Acid.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1187, doi. 10.1096/fasebj.21.6.a1187

By:

Radominska-Pandya, Anna;
Yan Xiong;
Bratton, Stacie;
Zielinska, Agnieszka;
Finel, Moshe

Publication type:

Article

Structural and functional analysis of aa3-type and cbb3-type cytochrome c oxidases of Paracoccus denitrificans reveals significant differences in proton-pump design.

Published in:

Molecular Microbiology, 1996, v. 20, n. 6, p. 1247, doi. 10.1111/j.1365-2958.1996.tb02644.x

By:

De Gier, Jan-Wiliem L.;
Schepper, Mike;
Reijnders, Willem N. M.;
Van Dyck, Stef J.;
Slotboom, Dirk Jan;
Warne, Antony;
Saraste, Matti;
Krab, Klaas;
Finel, Moshe;
Stouthamer, Adriaan H.;
van Spanning, Rob J. M.;
Van der Oost, John

Publication type:

Article

Genome-wide analyses of neonatal jaundice reveal a marked departure from adult bilirubin metabolism.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51947-w

By:

Solé-Navais, Pol;
Juodakis, Julius;
Ytterberg, Karin;
Wu, Xiaoping;
Bradfield, Jonathan P.;
Vaudel, Marc;
LaBella, Abigail L.;
Helgeland, Øyvind;
Flatley, Christopher;
Geller, Frank;
Finel, Moshe;
Zhao, Mengqi;
Lazarus, Philip;
Hakonarson, Hakon;
Magnus, Per;
Andreassen, Ole A.;
Njølstad, Pål R.;
Grant, Struan F. A.;
Feenstra, Bjarke;
Muglia, Louis J.

Publication type:

Article

Stereochemical and Steric Control of the UDP-Glucuronosyltransferase-Catalyzed Conjugation Reaction: A Rational Approach for the Design of Inhibitors for the Human UGT2B7.

Published in:

ChemMedChem, 2007, v. 2, n. 12, p. 1730, doi. 10.1002/cmdc.200700122

By:

Bichlmaier, Ingo;
Finel, Moshe;
Sippl, Wolfgang;
Yli-Kauhaluoma, Jari

Publication type:

Article

Potent Inhibitors of the Human UDP-Glucuronosyltransferase 2B7 Derived from the Sesquiterpenoid Alcohol Longifolol.

Published in:

ChemMedChem, 2007, v. 2, n. 6, p. 881, doi. 10.1002/cmdc.200600246

By:

Bichlmaier, Ingo;
Kurkela, Mika;
Joshi, Tanmaya;
Siiskonen, Antti;
Rüffer, Tobias;
Lang, Heinrich;
Finel, Moshe;
Yli-Kauhaluoma, Jari

Publication type:

Article

Crigler-Najjar syndrome in The Netherlands: Identification of four novel UGT1A1 alleles, genotype-phenotype correlation, and functional analysis of 10 missense mutants.

Published in:

Human Mutation, 2010, v. 31, n. 1, p. 52, doi. 10.1002/humu.21133

By:

Sneitz, Nina;
Bakker, Conny T.;
de Knegt, Robert J.;
Halley, Dicky J.J.;
Finel, Moshe;
Bosma, Piter J.

Publication type:

Article

Neobavaisoflavone Induces Bilirubin Metabolizing Enzyme UGT1A1 via PPARα and PPARγ.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.628314

By:

Zhu, Ya-Di;
Guan, Xiao-Qing;
Chen, Jing;
Peng, Sheng;
Finel, Moshe;
Zhao, Ying-Yuan;
Wang, Rui-Min;
Bi, Hui-Chang;
Lei, Ming;
Wang, Dan-Dan;
Ge, Guang-Bo

Publication type:

Article

Chiral distinction between the enantiomers of bicyclic alcohols by UDP-glucuronosyltransferases 2B7 and 2B17.

Published in:

Biological Chemistry, 2006, v. 387, n. 4, p. 407, doi. 10.1515/BC.2006.055

By:

Bichlmaier, Ingo;
Siiskonen, Antti;
Kurkela, Mika;
Finel, Moshe;
Yli-Kauhaluoma, Jari

Publication type:

Article

Fluorescence-Based High-Throughput Screening Assay for Drug Interactions with UGT1A6.

Published in:

Assay & Drug Development Technologies, 2011, v. 9, n. 5, p. 496, doi. 10.1089/adt.2010.0349

By:

Anne Soikkeli;
Mika Kurkela;
Jouni Hirvonen;
Marjo Yliperttula;
Moshe Finel

Publication type:

Article

Screening of natural compounds and their derivatives as potential protein kinase C inhibitors.

Published in:

Drug Development Research, 2004, v. 63, n. 2, p. 76, doi. 10.1002/ddr.10399

By:

Päivi Tammela;
Elina Ekokoski;
Arturo García‐Horsman;
Virpi Talman;
Moshe Finel;
Raimo Tuominen;
Pia Vuorela

Publication type:

Article

Case report by Toce and co‐authors: Have all the reasons for poor morphine glucuronidation been addressed?

Published in:

2019

By:

Finel, Moshe;
Järvinen, Erkka

Publication type:

Letter to the Editor

Anthraquinone biocolourant dermocybin is metabolized whereas dermorubin is not in in vitro liver fractions and recombinant metabolic enzymes.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2024, v. 134, n. 6, p. 846, doi. 10.1111/bcpt.14013

By:

Yli‐Öyrä, Johanna;
Juvonen, Risto O.;
Lehtonen, Marko;
Herrala, Mikko;
Finel, Moshe;
Räisänen, Riikka;
Rysä, Jaana

Publication type:

Article

Efflux transport of nicotine, cotinine and trans‐3′‐hydroxycotinine glucuronides by human hepatic transporters.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2019, v. 125, n. 6, p. 490, doi. 10.1111/bcpt.13281

By:

Järvinen, Erkka;
Sjöstedt, Noora;
Koenderink, Jan B.;
Kidron, Heidi;
Finel, Moshe

Publication type:

Article

The MELAS mutations 3946 and 3949 perturb the critical structure in a conserved loop of the ND1 subunit of mitochondrial complex I.

Published in:

Human Molecular Genetics, 2006, v. 15, n. 17, p. 2543, doi. 10.1093/hmg/ddl176

By:

Kervinen, Marko;
Hinttala, Reetta;
Helander, Heli M.;
Kurki, Sari;
Uusimaa, Johanna;
Finel, Moshe;
Majamaa, Kari;
Hassinen, Ilmo E.

Publication type:

Article

Determination of Serotonin and Dopamine Metabolites in Human Brain Microdialysis and Cerebrospinal Fluid Samples by UPLC-MS/MS: Discovery of Intact Glucuronide and Sulfate Conjugates.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0068007

By:

Suominen, Tina;
Uutela, Päivi;
Ketola, Raimo A.;
Bergquist, Jonas;
Hillered, Lars;
Finel, Moshe;
Zhang, Hongbo;
Laakso, Aki;
Kostiainen, Risto

Publication type:

Article

Albumin Stimulates the Activity of the Human UDP- Glucuronosyltransferases 1A7, 1A8, 1A10, 2A1 and 2B15, but the Effects Are Enzyme and Substrate Dependent.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054767

By:

Manevski, Nenad;
Troberg, Johanna;
Svaluto-Moreolo, Paolo;
Dziedzic, Klaudyna;
Yli-Kauhaluoma, Jari;
Finel, Moshe

Publication type:

Article

Substrate specificity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7.

Published in:

FEBS Journal, 2007, v. 274, n. 5, p. 1256, doi. 10.1111/j.1742-4658.2007.05670.x

By:

Barre, Lydia;
Fournel-Gigleux, Sylvie;
Finel, Moshe;
Netter, Patrick;
Magdalou, Jacques;
Ouzzine, Mohamed

Publication type:

Article

Characteristics of the aerobic respiratory chains of the microaerophiles Campylobacter jejuni and Helicobacter pylori.

Published in:

Archives of Microbiology, 2000, v. 174, n. 1/2, p. 1, doi. 10.1007/s002030000174

By:

Smith, Mark A.;
Finel, Moshe;
Korolik, Victoria;
Mendz, George L.

Publication type:

Article

Identification and characterization of human UDP-glucuronosyltransferases responsible for xanthotoxol glucuronidation.

Published in:

Xenobiotica, 2018, v. 48, n. 2, p. 109, doi. 10.1080/00498254.2017.1283719

By:

He, Guiyuan;
Troberg, Johanna;
Lv, Xia;
Xia, Yang-Liu;
Zhu, Liang-Liang;
Ning, Jing;
Ge, Guang-Bo;
Finel, Moshe;
Yang, Ling

Publication type:

Article

Bisphenol-A glucuronidation in human liver and breast: identification of UDP-glucuronosyltransferases (UGTs) and influence of genetic polymorphisms.

Published in:

Xenobiotica, 2017, v. 47, n. 1, p. 1, doi. 10.3109/00498254.2016.1156784

By:

Street, Christina M.;
Zhu, Zhaohui;
Finel, Moshe;
Court, Michael H.

Publication type:

Article

Differences in the glucuronidation of bisphenols F and S between two homologous human UGT enzymes, 1A9 and 1A10.

Published in:

Xenobiotica, 2015, v. 45, n. 6, p. 511, doi. 10.3109/00498254.2014.999140

By:

Gramec Skledar, Darja;
Troberg, Johanna;
Lavdas, Jason;
Peterlin Mašič, Lucija;
Finel, Moshe

Publication type:

Article

A high throughput assay for the glucuronidation of 7-hydroxy-4-trifluoromethylcoumarin by recombinant human UDP-glucuronosyltransferases and liver microsomes.

Published in:

Xenobiotica, 2013, v. 43, n. 10, p. 853, doi. 10.3109/00498254.2013.783724

By:

Rahikainen, Tuomas;
Häkkinen, Merja R.;
Finel, Moshe;
Pasanen, Markku;
Juvonen, Risto O.

Publication type:

Article

Quantitative distribution of mRNAs encoding the 19 human UDP-glucuronosyltransferase enzymes in 26 adult and 3 fetal tissues.

Published in:

Xenobiotica, 2012, v. 42, n. 3, p. 266, doi. 10.3109/00498254.2011.618954

By:

Court, Michael H.;
Zhang, Xiuling;
Ding, Xinxin;
Yee, Karen K.;
Hesse, Leah M.;
Finel, Moshe

Publication type:

Article

N-glucuronidation of drugs and other xenobiotics by human and animal UDP-glucuronosyltransferases.

Published in:

Xenobiotica, 2011, v. 41, n. 8, p. 652, doi. 10.3109/00498254.2011.563327

By:

Kaivosaari, Sanna;
Finel, Moshe;
Koskinen, Mikko

Publication type:

Article

Works by Finel, Moshe

High-throughput screening technologies for drug glucuronidation profiling.

Mutation analysis in UGT1A9 suggests a relationship between substrate and catalytic residues in UDP-glucuronosyltransferases.

Aspartic Acid<sup>393</sup> of the DxxD Motif within The C-Terminal Region of Human UDP-Glucuronosyltransferase 1A10 is Critical to the Binding of UDP-Glucuronic Acid.

Structural and functional analysis of aa<sub>3</sub>-type and cbb<sub>3</sub>-type cytochrome c oxidases of Paracoccus denitrificans reveals significant differences in proton-pump design.

Genome-wide analyses of neonatal jaundice reveal a marked departure from adult bilirubin metabolism.

Stereochemical and Steric Control of the UDP-Glucuronosyltransferase-Catalyzed Conjugation Reaction: A Rational Approach for the Design of Inhibitors for the Human UGT2B7.

Potent Inhibitors of the Human UDP-Glucuronosyltransferase 2B7 Derived from the Sesquiterpenoid Alcohol Longifolol.

Crigler-Najjar syndrome in The Netherlands: Identification of four novel UGT1A1 alleles, genotype-phenotype correlation, and functional analysis of 10 missense mutants.

Neobavaisoflavone Induces Bilirubin Metabolizing Enzyme UGT1A1 via PPARα and PPARγ.

Chiral distinction between the enantiomers of bicyclic alcohols by UDP-glucuronosyltransferases 2B7 and 2B17.

Fluorescence-Based High-Throughput Screening Assay for Drug Interactions with UGT1A6.

Screening of natural compounds and their derivatives as potential protein kinase C inhibitors.

Case report by Toce and co‐authors: Have all the reasons for poor morphine glucuronidation been addressed?

Anthraquinone biocolourant dermocybin is metabolized whereas dermorubin is not in in vitro liver fractions and recombinant metabolic enzymes.

Efflux transport of nicotine, cotinine and trans‐3′‐hydroxycotinine glucuronides by human hepatic transporters.

The MELAS mutations 3946 and 3949 perturb the critical structure in a conserved loop of the ND1 subunit of mitochondrial complex I.

Determination of Serotonin and Dopamine Metabolites in Human Brain Microdialysis and Cerebrospinal Fluid Samples by UPLC-MS/MS: Discovery of Intact Glucuronide and Sulfate Conjugates.

Albumin Stimulates the Activity of the Human UDP- Glucuronosyltransferases 1A7, 1A8, 1A10, 2A1 and 2B15, but the Effects Are Enzyme and Substrate Dependent.

Substrate specificity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7.

Characteristics of the aerobic respiratory chains of the microaerophiles Campylobacter jejuni and Helicobacter pylori.

Identification and characterization of human UDP-glucuronosyltransferases responsible for xanthotoxol glucuronidation.

Bisphenol-A glucuronidation in human liver and breast: identification of UDP-glucuronosyltransferases (UGTs) and influence of genetic polymorphisms.

Differences in the glucuronidation of bisphenols F and S between two homologous human UGT enzymes, 1A9 and 1A10.

A high throughput assay for the glucuronidation of 7-hydroxy-4-trifluoromethylcoumarin by recombinant human UDP-glucuronosyltransferases and liver microsomes.

Quantitative distribution of mRNAs encoding the 19 human UDP-glucuronosyltransferase enzymes in 26 adult and 3 fetal tissues.

N-glucuronidation of drugs and other xenobiotics by human and animal UDP-glucuronosyltransferases.