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Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control.
Published in:
2020
By:
- Xiaotong Cheng;
- Prange-Barczynska, Maria;
- Fielding, James W.;
- Minghao Zhang;
- Burrell, Alana L.;
- Lima, Joanna D. C. C.;
- Eckardt, Luise;
- Argles, Isobel L. A.;
- Pugh, Christopher W.;
- Buckler, Keith J.;
- Robbins, Peter A.;
- Hodson, Emma J.;
- Bruick, Richard K.;
- Collinson, Lucy M.;
- Rastinejad, Fraydoon;
- Bishop, Tammie;
- Ratcliffe, Peter J.;
- Cheng, Xiaotong;
- Zhang, Minghao;
- Lima, Joanna Dcc
Publication type:
journal article
PHD2 inactivation in Type I cells drives HIF‐2α‐dependent multilineage hyperplasia and the formation of paraganglioma‐like carotid bodies.
Published in:
Journal of Physiology, 2018, v. 596, n. 18, p. 4393, doi. 10.1113/JP275996
By:
- Hodson, Emma J.;
- Eckardt, Luise;
- Lip, Philomena;
- Maton‐Howarth, Matthew;
- Pugh, Christopher W.;
- Bishop, Tammie;
- Fielding, James W.;
- Cheng, Xiaotong;
- Adam, Julie;
- Ratcliffe, Peter J.;
- Ratnayaka, Indrika;
- Ferguson, David J. P.;
- Buckler, Keith J.
Publication type:
Article
Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF-2 pathway.
Published in:
Journal of Physiology, 2016, v. 594, n. 5, p. 1179, doi. 10.1113/JP271050
By:
- Hodson, Emma J.;
- Nicholls, Lynn G.;
- Turner, Philip J.;
- Llyr, Ronan;
- Fielding, James W.;
- Douglas, Gillian;
- Ratnayaka, Indrika;
- Robbins, Peter A.;
- Pugh, Christopher W.;
- Buckler, Keith J.;
- Ratcliffe, Peter J.;
- Bishop, Tammie
Publication type:
Article
Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2.
Published in:
Journal of Physiology, 2013, v. 591, n. 14, p. 3565, doi. 10.1113/jphysiol.2012.247254
By:
- Bishop, Tammie;
- Talbot, Nick P.;
- Turner, Philip J.;
- Nicholls, Lynn G.;
- Pascual, Alberto;
- Hodson, Emma J.;
- Douglas, Gillian;
- Fielding, James W.;
- Smith, Thomas G.;
- Demetriades, Marina;
- Schofield, Christopher J.;
- Robbins, Peter A.;
- Pugh, Christopher W.;
- Buckler, Keith J.;
- Ratcliffe, Peter J.
Publication type:
Article

Found: 4

Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control.

PHD2 inactivation in Type I cells drives HIF‐2α‐dependent multilineage hyperplasia and the formation of paraganglioma‐like carotid bodies.

Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF-2 pathway.

Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2.