Works by Ferrer, Isidre

Results: 200

Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance.

Published in:

Aging Cell, 2017, v. 16, n. 6, p. 1404, doi. 10.1111/acel.12682

By:

Fourcade, Stéphane;
Morató, Laia;
Parameswaran, Janani;
Ruiz, Montserrat;
Ruiz‐Cortés, Tatiana;
Jové, Mariona;
Naudí, Alba;
Martínez‐Redondo, Paloma;
Dierssen, Mara;
Ferrer, Isidre;
Villarroya, Francesc;
Pamplona, Reinald;
Vaquero, Alejandro;
Portero‐Otín, Manel;
Pujol, Aurora

Publication type:

Article

Altered Ca2+ homeostasis induces Calpain-Cathepsin axis activation in sporadic Creutzfeldt-Jakob disease.

Published in:

Acta Neuropathologica Communications, 2017, p. 1, doi. 10.1186/s40478-017-0431-y

By:

Llorens, Franc;
Thüne, Katrin;
Sikorska, Beata;
Schmitz, Matthias;
Tahir, Waqas;
Fernández-Borges, Natalia;
Cramm, Maria;
Gotzmann, Nadine;
Carmona, Margarita;
Streichenberger, Nathalie;
Michel, Uwe;
Zafar, Saima;
Schuetz, Anna-Lena;
Rajput, Ashish;
Andréoletti, Olivier;
Bonn, Stefan;
Fischer, Andre;
Liberski, Pawel P.;
Torres, Juan Maria;
Ferrer, Isidre

Publication type:

Article

Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS.

Published in:

Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-015-0271-6

By:

Cacabelos, Daniel;
Ramírez-Núñez, Omar;
Granado-Serrano, Ana Belén;
Torres, Pascual;
Ayala, Victòria;
Moiseeva, Victoria;
Povedano, Mònica;
Ferrer, Isidre;
Pamplona, Reinald;
Portero-Otin, Manuel;
Boada, Jordi

Publication type:

Article

Altered machinery of protein synthesis is region- and stage-dependent and is associated with α-synuclein oligomers in Parkinson's disease.

Published in:

Acta Neuropathologica Communications, 2015, v. 3, p. 1, doi. 10.1186/s40478-015-0257-4

By:

Garcia-Esparcia, Paula;
Hernández-Ortega, Karina;
Koneti, Anusha;
Gil, Laura;
Delgado-Morales, Raul;
Castaño, Ester;
Carmona, Margarita;
Ferrer, Isidre

Publication type:

Article

Clinical Correlations With Lewy Body Pathology in LRRK2-Related Parkinson Disease.

Published in:

JAMA Neurology, 2015, v. 72, n. 1, p. 100, doi. 10.1001/jamaneurol.2014.2704

By:

Kalia, Lorraine V.;
Lang, Anthony E.;
Hazrati, Lili-Naz;
Fujioka, Shinsuke;
Wszolek, Zbigniew K.;
Dickson, Dennis W.;
Ross, Owen A.;
Van Deerlin, Vivianna M.;
Trojanowski, John Q.;
Hurtig, Howard I.;
Alcalay, Roy N.;
Marder, Karen S.;
Clark, Lorraine N.;
Gaig, Carles;
Tolosa, Eduardo;
Ruiz-Martínez, Javier;
Marti-Masso, Jose F.;
Ferrer, Isidre;
López de Munain, Adolfo;
Goldman, Samuel M.

Publication type:

Article

Subtype and regional-specific neuroinflammation in sporadic Creutzfeldt–Jakob disease.

Published in:

Frontiers in Aging Neuroscience, 2014, v. 6, p. 1, doi. 10.3389/fnagi.2014.00198

By:

Llorens, Franc;
López-González, Irene;
Thüne, Katrin;
Carmona, Margarita;
Zafar, Saima;
Andréoletti, Olivier;
Zerr, Inga;
Ferrer, Isidre

Publication type:

Article

Late Infantile Neuronal Ceroid Lipofuscinosis: Mutations in the CLN2 Gene and Clinical Course in Spanish Patients.

Published in:

Journal of Child Neurology, 2013, v. 28, n. 4, p. 470, doi. 10.1177/0883073812448459

By:

Pérez-Poyato, María S.;
Marfa, Mercé Pineda;
Abizanda, Isidre Ferrer;
Rodriguez-Revenga, Laia;
Sánchez, Victoria Cusí;
González, María J Martínez;
Puñal, Jesús Eiris;
Pérez, Alfonso Verdú;
González, M Mar García;
Bermejo, Antonio Martínez;
Hernández, Elena Martín;
Rosell, M Josep Coll;
Gort, Laura;
Milá, Montserrat

Publication type:

Article

Increased 5-Methylcytosine and Decreased 5-Hydroxymethylcytosine Levels are Associated with Reduced Striatal AR Levels in Huntington's Disease.

Published in:

NeuroMolecular Medicine, 2013, v. 15, n. 2, p. 295, doi. 10.1007/s12017-013-8219-0

By:

Villar-Menéndez, Izaskun;
Blanch, Marta;
Tyebji, Shiraz;
Pereira-Veiga, Thais;
Albasanz, José;
Martín, Mairena;
Ferrer, Isidre;
Pérez-Navarro, Esther;
Barrachina, Marta

Publication type:

Article

High‐dose biotin restores redox balance, energy and lipid homeostasis, and axonal health in a model of adrenoleukodystrophy.

Published in:

Brain Pathology, 2020, v. 30, n. 5, p. 945, doi. 10.1111/bpa.12869

By:

Fourcade, Stéphane;
Goicoechea, Leire;
Parameswaran, Janani;
Schlüter, Agatha;
Launay, Nathalie;
Ruiz, Montserrat;
Seyer, Alexandre;
Colsch, Benoit;
Calingasan, Noel Ylagan;
Ferrer, Isidre;
Beal, M. Flint;
Sedel, Frédéric;
Pujol, Aurora

Publication type:

Article

Altered Machinery of Protein Synthesis in Alzheimer's: From the Nucleolus to the Ribosome.

Published in:

Brain Pathology, 2016, v. 26, n. 5, p. 593, doi. 10.1111/bpa.12335

By:

Hernández-Ortega, Karina;
Garcia-Esparcia, Paula;
Gil, Laura;
Lucas, José J.;
Ferrer, Isidre

Publication type:

Article

Complex Deregulation and Expression of Cytokines and Mediators of the Immune Response in Parkinson's Disease Brain is Region Dependent.

Published in:

Brain Pathology, 2014, v. 24, n. 6, p. 584, doi. 10.1111/bpa.12137

By:

Garcia‐Esparcia, Paula;
Llorens, Franc;
Carmona, Margarita;
Ferrer, Isidre

Publication type:

Article

Characterization of Thorn-Shaped Astrocytes in White Matter of Temporal Lobe in Alzheimer's Disease Brains.

Published in:

Brain Pathology, 2013, v. 23, n. 2, p. 144, doi. 10.1111/j.1750-3639.2012.00627.x

By:

López‐González, Irene;
Carmona, Margarita;
Blanco, Rosa;
Luna‐Muñoz, José;
Martínez‐Mandonado, Alejandra;
Mena, Raúl;
Ferrer, Isidre

Publication type:

Article

Deposition of Hyperphosphorylated Tau in Cerebellum of PS1 E280A Alzheimer's Disease.

Published in:

Brain Pathology, 2011, v. 21, n. 4, p. 452, doi. 10.1111/j.1750-3639.2010.00469.x

By:

Sepulveda-Falla, Diego;
Matschke, Jakob;
Bernreuther, Christian;
Hagel, Christian;
Puig, Berta;
Villegas, Andres;
Garcia, Gloria;
Zea, Julian;
Gomez-Mancilla, Baltazar;
Ferrer, Isidre;
Lopera, Francisco;
Glatzel, Markus

Publication type:

Article

Protein Targets of Oxidative Damage in Human Neurodegenerative Diseases with Abnormal Protein Aggregates.

Published in:

Brain Pathology, 2010, v. 20, n. 2, p. 281, doi. 10.1111/j.1750-3639.2009.00326.x

By:

Martínez, Anna;
Portero-Otin, Manuel;
Pamplona, Reinald;
Ferrer, Isidre

Publication type:

Article

Inter-Laboratory Assessment of PrPSc Typing in Creutzfeldt–Jakob Disease: A Western Blot Study within the NeuroPrion Consortium.

Published in:

Brain Pathology, 2009, v. 19, n. 3, p. 384, doi. 10.1111/j.1750-3639.2008.00187.x

By:

Parchi, Piero;
Notari, Silvio;
Weber, Petra;
Schimmel, Heinz;
Budka, Herbert;
Ferrer, Isidre;
Haik, Stéphane;
Hauw, Jean-Jacques;
WHead, Mark;
Ironside, James W.;
Limido, Lucia;
Rodriguez, Agustin;
Ströbel, Thomas;
Tagliavini, Fabrizio;
Kretzschmar, Hans A.

Publication type:

Article

Delineation of Early Changes in Cases with Progressive Supranuclear Palsy-Like Pathology. Astrocytes in Striatum are Primary Targets of Tau Phosphorylation and GFAP Oxidation.

Published in:

Brain Pathology, 2009, v. 19, n. 2, p. 177, doi. 10.1111/j.1750-3639.2008.00173.x

By:

Santpere, Gabriel;
Ferrer, Isidre

Publication type:

Article

Oxidative Stress in Desminopathies and Myotilinopathies: A Link between Oxidative Damage and Abnormal Protein Aggregation.

Published in:

Brain Pathology, 2007, v. 17, n. 4, p. 377, doi. 10.1111/j.1750-3639.2007.00087.x

By:

Janu, Anna;
Oliv, Montse;
Ferrer, Isidre

Publication type:

Article

Effects of Formalin Fixation, Paraffin Embedding, and Time of Storage on DNA Preservation in Brain Tissue: A BrainNet Europe Study.

Published in:

Brain Pathology, 2007, v. 17, n. 3, p. 297, doi. 10.1111/j.1750-3639.2007.00073.x

By:

Ferrer, Isidre;
Armstrong, Judith;
Capellari, Sabina;
Parchi, Piero;
Arzberger, Thomas;
Bell, Jeanne;
Budka, Herbert;
Ströbel, Thomas;
Giaccone, Giorgio;
Rossi, Giacomina;
Bogdanovic, Nenad;
Fakai, Peter;
Schmitt, Andrea;
Riederers, Peter;
Al-Sarraj, Safa;
Ravid, Rivka;
Kretzschmar, Hans

Publication type:

Article

Neuropathology and Pathogenesis of Encephalitis following Amyloid β Immunization in Alzheimer's Disease.

Published in:

Brain Pathology, 2004, v. 14, n. 1, p. 11, doi. 10.1111/j.1750-3639.2004.tb00493.x

By:

Ferrer, Isidre;
Rovira, Mercé Boada;
Guerra, María Luisa Sánchez;
Rey, María Jesús;
Costa-Jussá, Frederic

Publication type:

Article

A1 Adenosine Receptors Accumulate in Neurodegenerative Structures in Alzheimer's Disease and Mediate Both Amyloid Precursor Protein Processing and Tau Phosphorylation and Translocation.

Published in:

Brain Pathology, 2003, v. 13, n. 4, p. 440, doi. 10.1111/j.1750-3639.2003.tb00475.x

By:

Angulo, Ester;
Casadó, Vicent;
Mallol, Josefa;
Canela, Enric I.;
Viñals, Francesc;
Ferrer, Isidre;
Lluis, Carmen;
Franco, Rafael

Publication type:

Article

Chronic treatment with CB1 or CB2 cannabinoid receptors agonists reduces cognitive impairment in a transgenic model of Alzheimer's disease

Published in:

2010

By:

Aso, Ester;
Juvés, Salvador;
Maldonado, Rafael;
Ferrer, Isidre

Publication type:

Abstract

Non-enzymatic modifications increase in Alzheimer's disease

Published in:

2010

By:

Piñol-Ripoll, Gerard;
Kichev, Anton;
Ilieva, Ekaterina V.;
Podlesniy, Petar;
Ferrer, Isidre;
Portero-Otin, Manuel;
Pamplona, Reinald;
Purroy, Francisco;
Espinet, Carme

Publication type:

Abstract

Neuroimage in Alzheimer's disease: Results after plasma exchange with Human Albumin Grifols®

Published in:

2010

By:

Roca, Isabel;
Boada, Mercè;
Cuberas, Gemma;
Tárraga, Lluís;
Muñoz, Joan;
Grifols, Joan Ramon;
Ortiz, Pilar;
Hernández, Isabel;
Buendía, Mar;
Anaya, Fernando;
Olazarán, Javier;
Rubio, Lourdes;
Torres, Gustavo;
Ángel Bittini;
Guzmán de Villoria, Juan;
Núñez, Laura;
Páez, Antonio;
Ferrer, Isidre

Publication type:

Abstract

JNK signaling: A possible mechanism of beta-amyloid toxicity

Published in:

2010

By:

Mazzitelli, Sonia;
Ferrer, Isidre;
Yuan, Junying;
Tournier, Cathy

Publication type:

Abstract

The pathogenic I716F amyloid precursor protein (APP) mutation leads to a reduced protein processing and a very aggressive early-onset Alzheimer's disease

Published in:

2009

By:

Guardia-Laguarta, Cristina;
Pera, Marta;
Clarimon, Jordi;
Llado, Albert;
Sánchez-Valle, Raquel;
Molinuevo, Jose Luis;
Gómez-Isla, Teresa;
Blesa, Rafael;
Ferrer, Isidre;
Lleo, Alberto

Publication type:

Abstract

P4-388: An exploratory study of the potential utility of plasma exchange with five percent human albumin Grifols® in the treatment of Alzheimer's disease: Functional imaging (SPECT) findings

Published in:

2008

By:

Roca, Isabel;
Boada, Mercè;
Cuberas, Gemma;
Castell, Joan;
Tárraga, Lluis;
Muñoz, Joan;
Ortiz, Pilar;
Hernández, Isbel;
Buendía, Mar;
Pla, Ramón;
Ferrer, Isidre

Publication type:

Abstract

P4-355: An exploratory study of the potential utility of plasma exchange with 5 percent human albumin Grifols® in the treatment of Alzheimer's disease (AD)

Published in:

2008

By:

Boada, Mercè;
Munoz, Joan;
Tárraga, Lluis;
Ortiz, Pilar;
Hernández, Isabel;
Becker, James;
Lopez, Oscar;
Buendia, Mar;
Pla, Ramon;
Ferrer, Isidre

Publication type:

Abstract

P3-283: Familial early-onset Lewy body dementia: Clinical, pathological and genetic dissection

Published in:

2008

By:

Lleo, Alberto;
Ferrer, Isidre;
Molina, Laura;
Barraquer-Bordas, Luis;
Guardia, Cristina;
Gonzalez-Neira, Ana;
Blesa, Rafael;
Gómez-Isla, Teresa;
Roig, Carles;
Clarimon, Jordi

Publication type:

Abstract

P3-213: Genetic screening in a large cohort of early-onset Alzheimer's disease patients from Spain: Novel mutations in the amyloid precursor protein and presenilines

Published in:

2008

By:

Clarimón, Jordi;
Guerreiro, Rita;
Lleó, Alberto;
Guardia, Cristina;
Blesa, Rafael;
Gómez-Isla, Teresa;
Boada, Merce;
Bullido, Jesus;
Ferrer, Isidre;
Martínez-Lage, Pablo;
Masdeu, Jose;
Molina, Laura;
Molinuevo, José Luís;
Pastor, Pau;
Pérez-Tur, Jordi;
Rey, Jesus;
Sánchez-Valle, Raquel;
Tàrraga, Lluís;
Valdivieso, Fernando;
Singleton, Andrew

Publication type:

Abstract

P3-447: Abnormal alpha-synuclein solubility, aggregation and nitration in the frontal cortex in Pick’s disease

Published in:

2006

By:

Dalfo, Esther;
Martinez, Anna;
Muntané, Gerard;
Ferrer, Isidre

Publication type:

Abstract

P3-305: C-terminal Src kinase (CSK) is diminished in lipid rafts in Alzheimer’s disease

Published in:

2006

By:

Puig, Berta;
Santpere, Gabriel;
Ferrer, Isidre

Publication type:

Abstract

P3-299: Protein degradation related with post-mortem delay in the study of human neurodegenerative diseases. A proteomics approach

Published in:

2006

By:

Santpere, Gabriel;
Puig, Berta;
Ferrer, Isidre

Publication type:

Abstract

P2-021: The no-housed aging dog as a promising model of Alzheimer’s disease

Published in:

2006

By:

Pugliese, Marco;
Andrade, Carmen;
Mascort, Joan;
Ferrer, Isidre;
Mahy, Nicole

Publication type:

Abstract

P3-447: Abnormal alpha-synuclein solubility, aggregation and nitration in the frontal cortex in Pick’s disease

Published in:

2006

By:

Dalfo, Esther;
Martinez, Anna;
Muntané, Gerard;
Ferrer, Isidre

Publication type:

Abstract

P3-305: C-terminal Src kinase (CSK) is diminished in lipid rafts in Alzheimer’s disease

Published in:

2006

By:

Puig, Berta;
Santpere, Gabriel;
Ferrer, Isidre

Publication type:

Abstract

P3-299: Protein degradation related with post-mortem delay in the study of human neurodegenerative diseases. A proteomics approach

Published in:

2006

By:

Santpere, Gabriel;
Puig, Berta;
Ferrer, Isidre

Publication type:

Abstract

P2-021: The no-housed aging dog as a promising model of Alzheimer’s disease

Published in:

2006

By:

Pugliese, Marco;
Andrade, Carmen;
Mascort, Joan;
Ferrer, Isidre;
Mahy, Nicole

Publication type:

Abstract

Aprosodic speech with insular hyperintensities and 4R Tau pathology on autopsy.

Published in:

2013

By:

Beldarrain, Marian Gómez;
Ojeda, Javier Ruiz;
Ferrer, Isidre;
Garcia-Monco, Juan C

Publication type:

Journal Article

Aprosodic speech with insular hyperintensities and 4R Tau patholog y on autopsy.

Published in:

Neurocase (Taylor & Francis Ltd), 2013, v. 19, n. 6, p. 583, doi. 10.1080/13554794.2012.713489

By:

Beldarrain, Marian Gómez;
Ojeda, Javier Ruiz;
Ferrer, Isidre;
Garcia-Monco, Juan C.

Publication type:

Article

Cyclophilin D as a potential target for antioxidants in neurodegeneration: the X-ALD case.

Published in:

Biological Chemistry, 2013, v. 394, n. 5, p. 621, doi. 10.1515/hsz-2012-0323

By:

López-Erauskin, Jone;
Ferrer, Isidre;
Galea, Elena;
Pujol, Aurora

Publication type:

Article

Juvenile neuronal ceroid lipofuscinosis: clinical course and genetic studies in Spanish patients.

Published in:

Journal of Inherited Metabolic Disease, 2011, v. 34, n. 5, p. 1083, doi. 10.1007/s10545-011-9323-7

By:

Pérez-Poyato, María-Socorro;
Milà Recansens, Montserrat;
Ferrer Abizanda, Isidre;
Montero Sánchez, Raquel;
Rodríguez-Revenga, Laia;
Cusí Sánchez, Victoria;
García González, M.;
Domingo Jiménez, Rosario;
Camino León, Rafael;
Velázquez Fragua, Ramón;
Martínez-Bermejo, Antonio;
Pineda Marfà, Mercè

Publication type:

Article

Mitochondrial dysfunction in central nervous system white matter disorders.

Published in:

Glia (0894-1491), 2014, v. 62, n. 11, p. 1878, doi. 10.1002/glia.22670

By:

Morató, Laia;
Bertini, Enrico;
Verrigni, Daniela;
Ardissone, Anna;
Ruiz, Montse;
Ferrer, Isidre;
Uziel, Graziella;
Pujol, Aurora

Publication type:

Article

Promoter hypermethylation of the phosphatase DUSP22 mediates PKA-dependent TAU phosphorylation and CREB activation in Alzheimer's disease.

Published in:

Hippocampus, 2014, v. 24, n. 4, p. 363, doi. 10.1002/hipo.22245

By:

Sanchez‐Mut, Jose Vicente;
Aso, Ester;
Heyn, Holger;
Matsuda, Tadashi;
Bock, Christoph;
Ferrer, Isidre;
Esteller, Manel

Publication type:

Article

Activating cannabinoid receptor 2 preserves axonal health through GSK-3β/NRF2 axis in adrenoleukodystrophy.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 2, p. 241, doi. 10.1007/s00401-022-02451-2

By:

Parameswaran, Janani;
Goicoechea, Leire;
Planas-Serra, Laura;
Pastor, Antoni;
Ruiz, Montserrat;
Calingasan, Noel Y.;
Guilera, Cristina;
Aso, Ester;
Boada, Jordi;
Pamplona, Reinald;
Portero-Otín, Manuel;
de la Torre, Rafael;
Ferrer, Isidre;
Casasnovas, Carlos;
Pujol, Aurora;
Fourcade, Stéphane

Publication type:

Article

SFPQ and Tau: critical factors contributing to rapid progression of Alzheimer's disease.

Published in:

Acta Neuropathologica, 2020, v. 140, n. 3, p. 317, doi. 10.1007/s00401-020-02178-y

By:

Younas, Neelam;
Zafar, Saima;
Shafiq, Mohsin;
Noor, Aneeqa;
Siegert, Anna;
Arora, Amandeep Singh;
Galkin, Alexey;
Zafar, Ayesha;
Schmitz, Mathias;
Stadelmann, Christine;
Andreoletti, Olivier;
Ferrer, Isidre;
Zerr, Inga

Publication type:

Article

Tauroursodeoxycholic bile acid arrests axonal degeneration by inhibiting the unfolded protein response in X-linked adrenoleukodystrophy.

Published in:

Acta Neuropathologica, 2017, v. 133, n. 2, p. 283, doi. 10.1007/s00401-016-1655-9

By:

Launay, Nathalie;
Ruiz, Montserrat;
Grau, Laia;
Ortega, Francisco;
Ilieva, Ekaterina;
Martínez, Juan;
Galea, Elena;
Ferrer, Isidre;
Knecht, Erwin;
Pujol, Aurora;
Fourcade, Stéphane

Publication type:

Article

Retraction Note: In situ structural characterization of early amyloid aggregates in Alzheimer's disease transgenic mice and Octodon degus.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-76208-w

By:

Benseny-Cases, Núria;
Álvarez-Marimon, Elena;
Aso, Ester;
Carmona, Margarita;
Klementieva, Oxana;
Appelhans, Dietmar;
Ferrer, Isidre;
Cladera, Josep

Publication type:

Article

Retraction Note: In situ structural characterization of early amyloid aggregates in Alzheimer's disease transgenic mice and Octodon degus.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-76208-w

By:

Benseny-Cases, Núria;
Álvarez-Marimon, Elena;
Aso, Ester;
Carmona, Margarita;
Klementieva, Oxana;
Appelhans, Dietmar;
Ferrer, Isidre;
Cladera, Josep

Publication type:

Article

Genealogy of the neurodegenerative diseases based on a meta-analysis of age-stratified incidence data.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-75014-8

By:

Gerovska, Daniela;
Irizar, Haritz;
Otaegi, David;
Ferrer, Isidre;
López de Munain, Adolfo;
Araúzo-Bravo, Marcos J.

Publication type:

Article

Aberrant regulation of the GSK‐3β/NRF2 axis unveils a novel therapy for adrenoleukodystrophy.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 8, p. 1, doi. 10.15252/emmm.201708604

By:

Ranea‐Robles, Pablo;
Launay, Nathalie;
Ruiz, Montserrat;
Calingasan, Noel Ylagan;
Dumont, Magali;
Naudí, Alba;
Portero‐Otín, Manuel;
Pamplona, Reinald;
Ferrer, Isidre;
Beal, M. Flint;
Fourcade, Stéphane;
Pujol, Aurora

Publication type:

Article