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The nose is the best niche for detection of experimental pneumococcal colonisation in adults of all ages, using nasal wash.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-97807-1
By:
- Nikolaou, Elissavet;
- German, Esther L.;
- Blizard, Annie;
- Howard, Ashleigh;
- Hitchins, Lisa;
- Chen, Tao;
- Chadwick, Jim;
- Pojar, Sherin;
- Mitsi, Elena;
- Solórzano, Carla;
- Sunny, Syba;
- Dunne, Felicity;
- Gritzfeld, Jenna F.;
- Adler, Hugh;
- Hinds, Jason;
- Gould, Katherine A.;
- Rylance, Jamie;
- Collins, Andrea M.;
- Gordon, Stephen B.;
- Ferreira, Daniela M.
Publication type:
Article
Saliva Alternative to Upper Respiratory Swabs for SARS-CoV-2 Diagnosis.
Published in:
Emerging Infectious Diseases, 2020, v. 26, n. 11, p. 2769, doi. 10.3201/eid2611.203283
By:
- Byrne, Rachel L.;
- Kay, Grant A.;
- Kontogianni, Konstantina;
- Aljayyoussi, Ghaith;
- Brown, Lottie;
- Collins, Andrea M.;
- Cuevas, Luis E.;
- Ferreira, Daniela M.;
- Fraser, Alice J.;
- Garrod, Gala;
- Hill, Helen;
- Hughes, Grant L.;
- Menzies, Stefanie;
- Mitsi, Elena;
- Owen, Sophie I.;
- Patterson, Edward I.;
- Williams, Christopher T.;
- Hyder-Wright, Angela;
- Adams, Emily R.;
- Cubas-Atienzar, Ana I.
Publication type:
Article
Intracellular survival of Streptococcus pneumoniae in human alveolar macrophages is augmented with HIV infection.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.992659
By:
- Nyazika, Tinashe K.;
- Sibale, Lusako;
- Phiri, Joseph;
- De Ste Croix, Megan;
- Jasiunaite, Zydrune;
- Mkandawire, Christopher;
- Malamba, Rose;
- Kankwatira, Anstead;
- Manduwa, Miriam;
- Ferreira, Daniela M.;
- Nyirenda, Tonney S.;
- Oggioni, Marco R.;
- Mwandumba, Henry C.;
- Jambo, Kondwani C.
Publication type:
Article
Admission hypothermia, neonatal morbidity, and mortality: evaluation of a multicenter cohort of very low birth weight preterm infants according to relative performance of the center.
Published in:
2019
By:
- de Siqueira Caldas, Jamil Pedro;
- Ferri, Walusa A. G.;
- Marba, Sérgio T. M.;
- Aragon, Davi C.;
- Guinsburg, Ruth;
- de Almeida, Maria F. B.;
- Diniz, Edna M. A.;
- Silveira, Rita C. S.;
- Alves Junior, José M. S.;
- Pavanelli, Marco B.;
- Bentlin, Maria R.;
- Ferreira, Daniela M. L. M.;
- Vale, Marynéa S.;
- Fiori, Humberto H.;
- Duarte, José L. M. B.;
- Meneses, Jucille A.;
- Cwajg, Silvia;
- Carvalho, Werther B.;
- Ferrari, Lígia S. L.;
- Silva, Nathalia M. M.
Publication type:
journal article
Participant perceptions and experiences of a novel community-based respiratory longitudinal sampling method in Liverpool, UK: A mixed methods feasibility study.
Published in:
PLoS ONE, 2023, v. 18, n. 11, p. 1, doi. 10.1371/journal.pone.0294133
By:
- German, Esther L.;
- Nabwera, Helen M.;
- Robinson, Ryan;
- Shiham, Farah;
- Liatsikos, Kostas;
- Parry, Christopher M.;
- McNamara, Claire;
- Kattera, Sanjana;
- Carter, Katie;
- Howard, Ashleigh;
- Pojar, Sherin;
- Hamilton, Joshua;
- Matope, Agnes;
- Read, Jonathan M.;
- Allen, Stephen J.;
- Hill, Helen;
- Hawcutt, Daniel B.;
- Urban, Britta C.;
- Collins, Andrea M.;
- Ferreira, Daniela M.
Publication type:
Article
Nasopharyngeal colonisation with Streptococcus pneumoniae in malnourished children: a systematic review and meta-analysis of prevalence.
Published in:
Transactions of the Royal Society of Tropical Medicine & Hygiene, 2019, v. 113, n. 5, p. 227, doi. 10.1093/trstmh/try139
By:
- Smith, Holly C;
- German, Esther;
- Ferreira, Daniela M;
- Rylance, Jamie
Publication type:
Article
Antibodies Reactive to Commensal Streptococcus mitis Show Cross-Reactivity With Virulent Streptococcus pneumoniae Serotypes.
Published in:
Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00747
By:
- Shekhar, Sudhanshu;
- Khan, Rabia;
- Ferreira, Daniela M.;
- Mitsi, Elena;
- German, Esther;
- Rørvik, Gro Herredsvela;
- Berild, Dag;
- Schenck, Karl;
- Kwon, Keehwan;
- Petersen, Fernanda
Publication type:
Article
Insights Into the Effects of Mucosal Epithelial and Innate Immune Dysfunction in Older People on Host Interactions With Streptococcus pneumoniae.
Published in:
Frontiers in Cellular & Infection Microbiology, 2021, p. 1, doi. 10.3389/fcimb.2021.651474
By:
- Weight, Caroline M.;
- Jochems, Simon P.;
- Adler, Hugh;
- Ferreira, Daniela M.;
- Brown, Jeremy S.;
- Heyderman, Robert S.
Publication type:
Article
Multi-omics analysis reveals COVID-19 vaccine induced attenuation of inflammatory responses during breakthrough disease.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47463-6
By:
- Drury, Ruth E.;
- Camara, Susana;
- Chelysheva, Irina;
- Bibi, Sagida;
- Sanders, Katherine;
- Felle, Salle;
- Emary, Katherine;
- Phillips, Daniel;
- Voysey, Merryn;
- Ferreira, Daniela M.;
- Klenerman, Paul;
- Gilbert, Sarah C.;
- Lambe, Teresa;
- Pollard, Andrew J.;
- O'Connor, Daniel
Publication type:
Article
Respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42433-w
By:
- Mitsi, Elena;
- Diniz, Mariana O.;
- Reiné, Jesús;
- Collins, Andrea M.;
- Robinson, Ryan E.;
- Hyder-Wright, Angela;
- Farrar, Madlen;
- Liatsikos, Konstantinos;
- Hamilton, Josh;
- Onyema, Onyia;
- Urban, Britta C.;
- Solórzano, Carla;
- Belij-Rammerstorfer, Sandra;
- Sheehan, Emma;
- Lambe, Teresa;
- Draper, Simon J.;
- Weiskopf, Daniela;
- Sette, Alessandro;
- Maini, Mala K.;
- Ferreira, Daniela M.
Publication type:
Article
Combination of Pneumococcal Surface Protein A (PspA) with Whole Cell Pertussis Vaccine Increases Protection Against Pneumococcal Challenge in Mice.
Published in:
PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010863
By:
- Oliveira, Maria Leonor S.;
- Miyaji, Eliane N.;
- Ferreira, Daniela M.;
- Moreno, Adriana T.;
- Ferreira, Patricia C. D.;
- Lima, Fernanda A.;
- Santos, Fernanda L.;
- Sakauchi, Maria Aparecida;
- Takata, Célia S.;
- Higashi, Hisako G.;
- Raw, Isaías;
- Kubrusly, Flavia S.;
- Ho, Paulo L.
Publication type:
Article
Oral Typhoid Vaccination With Live-Attenuated Salmonella Typhi Strain Ty21a Generates Ty21a-Responsive and Heterologous Influenza Virus-Responsive CD4+ and CD8+ T Cells at the Human Intestinal Mucosa.
Published in:
2016
By:
- Pennington, Shaun H.;
- Thompson, Ameeka L.;
- Wright, Adam K. A.;
- Ferreira, Daniela M.;
- Jambo, Kondwani C.;
- Wright, Angela D.;
- Faragher, Brian;
- Gilmour, Jill W.;
- Gordon, Stephen B.;
- Gordon, Melita A.
Publication type:
journal article
Preclinical Development of Virulence-attenuated Strains Able to Enhance Protective Immunity against Pneumococcal Infection.
Published in:
2021
By:
- Ramos-Sevillano, Elisa;
- Felgner, Philip;
- Goldblatt, David;
- Heyderman, Robert S.;
- Gordon, Stephen B.;
- Ferreira, Daniela M.;
- Brown, Jeremy S.;
- Ercoli, Giuseppe;
- Ramiro de Assis, Rafael;
- Nakajima, Rie
Publication type:
Letter
Nasal Pneumococcal Density Is Associated with Microaspiration and Heightened Human Alveolar Macrophage Responsiveness to Bacterial Pathogens.
Published in:
2020
By:
- Mitsi, Elena;
- Carniel, Beatriz;
- Reine, Jesus;
- Rylance, Jamie;
- Zaidi, Seher;
- Soares-Schanoski, Alessandra;
- Connor, Victoria;
- Collins, Andrea M.;
- Schlitzer, Andreas;
- Nikolaou, Elissavet;
- Solorzano, Carla;
- Pojar, Sherin;
- Hill, Helen;
- Hyder-Wright, Angela D.;
- Jambo, Kondwani C.;
- Oggioni, Marco R.;
- De Ste Croix, Megan;
- Gordon, Stephen B.;
- Jochems, Simon P.;
- Ferreira, Daniela M.
Publication type:
journal article
Two Randomized Trials of the Effect of Live Attenuated Influenza Vaccine on Pneumococcal Colonization.
Published in:
2019
By:
- Rylance, Jamie;
- de Steenhuijsen Piters, Wouter A A;
- Mina, Michael J;
- Bogaert, Debby;
- French, Neil;
- Ferreira, Daniela M;
- EHPC-LAIV Study Group
Publication type:
Letter
Polysaccharide-Specific Memory B Cells Predict Protection against Experimental Human Pneumococcal Carriage.
Published in:
2016
By:
- Pennington, Shaun H.;
- Pojar, Sherin;
- Mitsi, Elena;
- Gritzfeld, Jenna F.;
- Nikolaou, Elissavet;
- órzano, Carla Sol;
- Owugha, Jessica T.;
- Masood, Qasim;
- Gordon, Melita A.;
- Wright, Angela D.;
- Collins, Andrea M.;
- Miyaji, Eliane N.;
- Gordon, Stephen B.;
- Ferreira, Daniela M.;
- Solórzano, Carla
Publication type:
journal article
When Do Coughs and Sneezes Cause Diseases?
Published in:
2016
By:
- Gordon, Stephen;
- Ferreira, Daniela M.
Publication type:
journal article
First human challenge testing of a pneumococcal vaccine. Double-blind randomized controlled trial.
Published in:
2015
By:
- Collins, Andrea M.;
- Wright, Angela D.;
- Mitsi, Elena;
- Gritzfeld, Jenna F.;
- Hancock, Carole A.;
- Pennington, Shaun H.;
- Duolao Wang;
- Morton, Ben;
- Ferreira, Daniela M.;
- Gordon, Stephen B.;
- Wang, Duolao
Publication type:
journal article
Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11005-2
By:
- Weight, Caroline M.;
- Venturini, Cristina;
- Pojar, Sherin;
- Jochems, Simon P.;
- Reiné, Jesús;
- Nikolaou, Elissavet;
- Solórzano, Carla;
- Noursadeghi, Mahdad;
- Brown, Jeremy S.;
- Ferreira, Daniela M.;
- Heyderman, Robert S.
Publication type:
Article
Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10814-9
By:
- de Steenhuijsen Piters, Wouter A. A.;
- Jochems, Simon P.;
- Mitsi, Elena;
- Rylance, Jamie;
- Pojar, Sherin;
- Nikolaou, Elissavet;
- German, Esther L.;
- Holloway, Mark;
- Carniel, Beatriz F.;
- Chu, Mei Ling J. N.;
- Arp, Kayleigh;
- Sanders, Elisabeth A. M.;
- Ferreira, Daniela M.;
- Bogaert, Debby
Publication type:
Article
Serum levels of anti-PspA and anti-PspC IgG decrease with age and do not correlate with susceptibility to experimental human pneumococcal colonization.
Published in:
PLoS ONE, 2021, v. 16, n. 2, p. 1, doi. 10.1371/journal.pone.0247056
By:
- Araujo, Adriano P.;
- Colichio, Gabriela B. C.;
- Oliveira, Maria Leonor S.;
- German, Esther;
- Nikolaou, Elissavet;
- Chen, Tao;
- Adler, Hugh;
- Ferreira, Daniela M.;
- Miyaji, Eliane N.
Publication type:
Article
Human alveolar macrophages predominately express combined classical M1 and M2 surface markers in steady state.
Published in:
2018
By:
- Mitsi, Elena;
- Kamng'ona, Raphael;
- Rylance, Jamie;
- Solórzano, Carla;
- Jesus Reiné, J.;
- Mwandumba, Henry C.;
- Ferreira, Daniela M.;
- Jambo, Kondwani C.
Publication type:
Letter
Baseline gene signatures of reactogenicity to Ebola vaccination: a machine learning approach across multiple cohorts.
Published in:
Frontiers in Immunology, 2023, v. 14, p. 01, doi. 10.3389/fimmu.2023.1259197
By:
- Gonzalez Dias Carvalho, Patrícia Conceição;
- Dominguez Crespo Hirata, Thiago;
- Yukio Mano Alves, Leandro;
- Franco Moscardini, Isabelle;
- Barbosa do Nascimento, Ana Paula;
- Costa-Martins, Andre G.;
- Sorgi, Sara;
- Harandi, Ali M.;
- Ferreira, Daniela M.;
- Vianello, Eleonora;
- Haks, Marièlle C.;
- Ottenhoff, Tom H. M.;
- Santoro, Francesco;
- Martinez-Murillo, Paola;
- Huttner, Angela;
- Siegrist, Claire-Anne;
- Medaglini, Donata;
- Nakaya, Helder I.
Publication type:
Article
Pneumococcal colonisation is an asymptomatic event in healthy adults using an experimental human colonisation model.
Published in:
PLoS ONE, 2020, v. 15, n. 3, p. 1, doi. 10.1371/journal.pone.0229558
By:
- Trimble, Ashleigh;
- Connor, Victoria;
- Robinson, Ryan E.;
- McLenaghan, Daniella;
- Hancock, Carole A.;
- Wang, Duolao;
- Gordon, Stephen B.;
- Ferreira, Daniela M.;
- Wright, Angela D.;
- Collins, Andrea M.
Publication type:
Article
Controlled human infection and rechallenge with Streptococcus pneumoniae reveals the protective efficacy of carriage in healthy adults.
Published in:
2013
By:
- Ferreira, Daniela M;
- Neill, Daniel R;
- Bangert, Mathieu;
- Gritzfeld, Jenna F;
- Green, Nicola;
- Wright, Adam K A;
- Pennington, Shaun H;
- Moreno, Laura Bricio;
- Moreno, Adriana T;
- Miyaji, Eliane N;
- Wright, Angela D;
- Collins, Andrea M;
- Goldblatt, David;
- Kadioglu, Aras;
- Gordon, Stephen B;
- Bricio-Moreno, Laura
Publication type:
journal article
Controlled Human Infection and Rechallenge with Streptococcus pneumoniae Reveals the Protective Efficacy of Carriage in Healthy Adults.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2013, v. 187, n. 8, p. 855, doi. 10.1164/rccm.201212-2277oc
By:
- Ferreira, Daniela M.;
- Neill, Daniel R.;
- Bangert, Mathleu;
- Gritzfeld, Jenna F.;
- Green, Nicola;
- Wright, Adam K. A.;
- Pennington, Shaun H.;
- Moreno, Laura Brlcio;
- Moreno, Adriana T.;
- Miyaji, Ellane N.;
- Wright, Angela D.;
- Collins, Andrea M.;
- Goldblatt, David;
- Kadioglu, Aras;
- Gordon, Stephen B.
Publication type:
Article
Experimental Human Pneumococcal Carriage Augments IL-17A-dependent T-cell Defence of the Lung.
Published in:
PLoS Pathogens, 2013, v. 9, n. 3, p. 1, doi. 10.1371/journal.ppat.1003274
By:
- Wright, Adam K. A.;
- Bangert, Mathieu;
- Gritzfeld, Jenna F.;
- Ferreira, Daniela M.;
- Jambo, Kondwani C.;
- Wright, Angela D.;
- Collins, Andrea M.;
- Gordon, Stephen B.
Publication type:
Article
T Regulatory Cells Control Susceptibility to Invasive Pneumococcal Pneumonia in Mice.
Published in:
PLoS Pathogens, 2012, v. 8, n. 4, p. 1, doi. 10.1371/journal.ppat.1002660
By:
- Neill, Daniel R.;
- Fernandes, Vitor E.;
- Wisby, Laura;
- Haynes, Andrew R.;
- Ferreira, Daniela M.;
- Laher, Ameera;
- Strickland, Natalie;
- Gordon, Stephen B.;
- Denny, Paul;
- Kadioglu, Aras;
- Andrew, Peter W.
Publication type:
Article
Human Nasal Challenge with Streptococcus pneumoniae Is Immunising in the Absence of Carriage.
Published in:
PLoS Pathogens, 2012, v. 8, n. 4, p. 1, doi. 10.1371/journal.ppat.1002622
By:
- Wright, Adam K. A.;
- Ferreira, Daniela M.;
- Gritzfeld, Jenna F.;
- Wright, Angela D.;
- Armitage, Kathryn;
- Jambo, Kondwani C.;
- Bate, Emily;
- El Batrawy, Sherouk;
- Collins, Andrea;
- Gordon, Stephen B.
Publication type:
Article
Obesity, leptin and host defence of Streptococcus pneumoniae: the case for more human research.
Published in:
European Respiratory Review, 2022, v. 31, n. 165, p. 1, doi. 10.1183/16000617.0055-2022
By:
- Hales, Caz;
- Burnet, Laura;
- Coombs, Maureen;
- Collins, Andrea M.;
- Ferreira, Daniela M.
Publication type:
Article
Novel Analysis of Immune Cells from Nasal Microbiopsy Demonstrates Reliable, Reproducible Data for Immune Populations, and Superior Cytokine Detection Compared to Nasal Wash.
Published in:
PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0169805
By:
- Jochems, Simon P.;
- Piddock, Katherine;
- Rylance, Jamie;
- Adler, Hugh;
- Carniel, Beatriz F.;
- Collins, Andrea;
- Gritzfeld, Jenna F.;
- Hancock, Carole;
- Hill, Helen;
- Reiné, Jesus;
- Seddon, Alexandra;
- Solórzano, Carla;
- Sunny, Syba;
- Trimble, Ashleigh;
- Wright, Angela D.;
- Zaidi, Seher;
- Gordon, Stephen B.;
- Ferreira, Daniela M.
Publication type:
Article
The immunological mechanisms that control pneumococcal carriage.
Published in:
PLoS Pathogens, 2017, v. 13, n. 12, p. 1, doi. 10.1371/journal.ppat.1006665
By:
- Jochems, Simon P.;
- Weiser, Jeffrey N.;
- Malley, Richard;
- Ferreira, Daniela M.
Publication type:
Article
Combinatorial multimer staining and spectral flow cytometry facilitate quantification and characterization of polysaccharide-specific B cell immunity.
Published in:
Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-05444-3
By:
- Hoving, Dennis;
- Marques, Alexandre H. C.;
- Huisman, Wesley;
- Nosoh, Beckley A.;
- de Kroon, Alicia C.;
- van Hengel, Oscar R. J.;
- Wu, Bing-Ru;
- Steenbergen, Rosanne A. M.;
- van Helden, Pauline M.;
- Urban, Britta C.;
- Dhar, Nisha;
- Ferreira, Daniela M.;
- Kwatra, Gaurav;
- Hokke, Cornelis H.;
- Jochems, Simon P.
Publication type:
Article
Antibiotic Resistance Is Associated with Integrative and Conjugative Elements and Genomic Islands in Naturally Circulating Streptococcus pneumoniae Isolates from Adults in Liverpool, UK.
Published in:
Genes, 2020, v. 11, n. 6, p. 625, doi. 10.3390/genes11060625
By:
- Nikolaou, Elissavet;
- Hubbard, Alasdair T. M.;
- Botelho, João;
- Marschall, Taylor A. M.;
- Ferreira, Daniela M.;
- Roberts, Adam P.
Publication type:
Article
Thirteen-Valent Pneumococcal Conjugate Vaccine-Induced Immunoglobulin G (IgG) Responses in Serum Associated With Serotype-Specific IgG in the Lung.
Published in:
2022
By:
- Mitsi, Elena;
- McLenaghan, Daniella;
- Wolf, Asia-Sophia;
- Jones, Scott;
- Collins, Andrea M;
- Hyder-Wright, Angela D;
- Goldblatt, David;
- Heyderman, Robert S;
- Gordon, Stephen B;
- Ferreira, Daniela M
Publication type:
journal article
Pneumococcal Colonization in Healthy Adult Research Participants in the Conjugate Vaccine Era, United Kingdom, 2010-2017.
Published in:
2019
By:
- Adler, Hugh;
- Nikolaou, Elissavet;
- Gould, Katherine;
- Hinds, Jason;
- Collins, Andrea M;
- Connor, Victoria;
- Hales, Caz;
- Hill, Helen;
- Hyder-Wright, Angela D;
- Zaidi, Seher R;
- German, Esther L;
- Gritzfeld, Jenna F;
- Mitsi, Elena;
- Pojar, Sherin;
- Gordon, Stephen B;
- Roberts, Adam P;
- Rylance, Jamie;
- Ferreira, Daniela M
Publication type:
journal article
Mucosal immunization with PspA (Pneumococcal surface protein A)-adsorbed nanoparticles targeting the lungs for protection against pneumococcal infection.
Published in:
PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0191692
By:
- Rodrigues, Tasson C.;
- Oliveira, Maria Leonor S.;
- Soares-Schanoski, Alessandra;
- Chavez-Rico, Stefanni L.;
- Figueiredo, Douglas B.;
- Gonçalves, Viviane M.;
- Ferreira, Daniela M.;
- Kunda, Nitesh K.;
- Saleem, Imran Y.;
- Miyaji, Eliane N.
Publication type:
Article
Estimating pneumococcal carriage dynamics in adults living with HIV in a mature infant pneumococcal conjugate vaccine programme in Malawi, a modelling study.
Published in:
BMC Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12916-024-03631-5
By:
- Phiri, Joseph;
- Sibale, Lusako;
- Mlongoti, Lukerensia;
- Mitole, Ndaona;
- Kusakala, Alice;
- Khwiya, Mercy;
- Kayembe, Thokozani;
- Lisimba, Edwin;
- Kapwata, Prosperina;
- Malisita, Ken;
- Chaguza, Chrispin;
- Ferreira, Daniela M.;
- Thindwa, Deus;
- Jambo, Kondwani
Publication type:
Article

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