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Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease.
- Published in:
- Nature Medicine, 2000, v. 6, n. 7, p. 797, doi. 10.1038/77528
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- Article
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.
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- Nature Medicine, 1999, v. 5, n. 3, p. 347, doi. 10.1038/6568
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- Article
Prophylactic Creatine Administration Mediates Neuroprotection in Cerebral Ischemia in Mice.
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- Journal of Neuroscience, 2004, v. 24, n. 26, p. 5909, doi. 10.1523/JNEUROSCI.1278-04.2004
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- Article
Histone Deacetylase Inhibition by Sodium Butyrate Chemotherapy Ameliorates the Neurodegenerative Phenotype in Huntington's Disease Mice.
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- Journal of Neuroscience, 2003, v. 23, n. 28, p. 9418, doi. 10.1523/JNEUROSCI.23-28-09418.2003
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- Publication type:
- Article
Sp1 and Sp3 Are Oxidative Stress-Inducible, Antideath Transcription Factors in Cortical Neurons.
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- Journal of Neuroscience, 2003, v. 23, n. 9, p. 3597, doi. 10.1523/JNEUROSCI.23-09-03597.2003
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- Article
Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease.
- Published in:
- 2011
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- Publication type:
- journal article
Experimental therapeutics in transgenic mouse models of Huntington's disease.
- Published in:
- Nature Reviews Neuroscience, 2004, v. 5, n. 5, p. 373, doi. 10.1038/nrn1386
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- Article
Botulinum a toxin for the treatment of spasmodic torticollis: Dysphagia and regional toxin spread.
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- Head & Neck, 1990, v. 12, n. 5, p. 392, doi. 10.1002/hed.2880120504
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- Article
Evidence of Oxidant Damage in Huntington's Disease: Translational Strategies Using Antioxidants.
- Published in:
- Annals of the New York Academy of Sciences, 2008, v. 1147, p. 79, doi. 10.1196/annals.1427.008
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- Article
3-Acetylpyridine Produces Age-Dependent Excitotoxic Lesions in Rat Striatum.
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- Journal of Cerebral Blood Flow & Metabolism, 1994, v. 14, n. 6, p. 1024, doi. 10.1038/jcbfm.1994.134
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- Article
Neurotoxicity and Oxidative Damage of Beta Amyloid 1-42 versus Beta Amyloid 1-40 in the Mouse Cerebral Cortex.
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- Annals of the New York Academy of Sciences, 1999, v. 893, n. 1, p. 314, doi. 10.1111/j.1749-6632.1999.tb07845.x
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- Article
Differential sparing of somatostatin-neuropeptide y and cholinergic neurons following striatal excitotoxin lesions.
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- Synapse, 1989, v. 3, n. 1, p. 38, doi. 10.1002/syn.890030106
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- Publication type:
- Article
Inhibitors of Cytochrome c Release with Therapeutic Potential for Huntington's Disease.
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- Journal of Neuroscience, 2008, v. 28, n. 38, p. 9473, doi. 10.1523/JNEUROSCI.1867-08.2008
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- Publication type:
- Article
Neuroprotective Effects of Synaptic Modulation in Huntington's Disease R6/2 Mice.
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- Journal of Neuroscience, 2007, v. 27, n. 47, p. 12908, doi. 10.1523/JNEUROSCI.4318-07.2007
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- Publication type:
- Article
Chemotherapy for the Brain: The Antitumor Antibiotic Mithramycin Prolongs Survival in a Mouse Model of Huntington's Disease.
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- Journal of Neuroscience, 2004, v. 24, n. 46, p. 10335, doi. 10.1523/JNEUROSCI.2599-04.2004
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- Publication type:
- Article
Activation of Ets-2 by oxidative stress induces Bcl-xL expression and accounts for glial survival in amyotrophic lateral sclerosis.
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- FASEB Journal, 2009, v. 23, n. 6, p. 1739, doi. 10.1096/fj.08-121046
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- Article
Oxidative Stress in Huntington's Disease.
- Published in:
- Brain Pathology, 1999, v. 9, n. 1, p. 147, doi. 10.1111/j.1750-3639.1999.tb00216.x
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- Publication type:
- Article
Role of cyclooxygenase-2 induction by transcription factor Sp1 and Sp3 in neuronal oxidative and DNA damage response.
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- FASEB Journal, 2006, v. 20, n. 13, p. 2375, doi. 10.1096/fj.06-5957fje
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- Publication type:
- Article
Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice.
- Published in:
- Nature, 2002, v. 417, n. 6884, p. 74, doi. 10.1038/417074a
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- Article
A call for transparent reporting to optimize the predictive value of preclinical research.
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- Nature, 2012, v. 490, n. 7419, p. 187, doi. 10.1038/nature11556
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- Article
Inhibition of mitochondrial protein import by mutant huntingtin.
- Published in:
- Nature Neuroscience, 2014, v. 17, n. 6, p. 822, doi. 10.1038/nn.3721
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- Publication type:
- Article
Nortriptyline delays disease onset in models of chronic neurodegeneration.
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- European Journal of Neuroscience, 2007, v. 26, n. 3, p. 633, doi. 10.1111/j.1460-9568.2007.05663.x
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- Publication type:
- Article
3-Nitropropionic Acid Neurotoxicity Is Attenuated in Copper/Zinc Superoxide Dismutase Transgenic Mice.
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- Journal of Neurochemistry, 1995, v. 65, n. 2, p. 919, doi. 10.1046/j.1471-4159.1995.65020919.x
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- Publication type:
- Article
Involvement of Free Radicals in Excitotoxicity In Vivo.
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- Journal of Neurochemistry, 1995, v. 64, n. 5, p. 2239, doi. 10.1046/j.1471-4159.1995.64052239.x
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- Publication type:
- Article
Age-Dependent Vulnerability of the Striatum to the Mitochondrial Toxin 3-Nitropropionic Acid.
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- Journal of Neurochemistry, 1993, v. 60, n. 1, p. 356, doi. 10.1111/j.1471-4159.1993.tb05859.x
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- Article
Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease.
- Published in:
- Human Molecular Genetics, 2010, v. 19, n. 20, p. 3919, doi. 10.1093/hmg/ddq306
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- Publication type:
- Article
In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects.
- Published in:
- Human Molecular Genetics, 2010, v. 19, n. 15, p. 3053, doi. 10.1093/hmg/ddq212
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- Publication type:
- Article
Monoallele deletion of CBP leads to pericentromeric heterochromatin condensation through ESET expression and histone H3 (K9) methylation.
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- Human Molecular Genetics, 2008, v. 17, n. 12, p. 1774, doi. 10.1093/hmg/ddn067
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- Publication type:
- Article
Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage.
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- Human Molecular Genetics, 2007, v. 16, n. 15, p. 1845, doi. 10.1093/hmg/ddm133
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- Article
Modulation of nucleosome dynamics in Huntington's disease.
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- Human Molecular Genetics, 2007, v. 16, n. 10, p. 1164, doi. 10.1093/hmg/ddm064
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- Publication type:
- Article
Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease.
- Published in:
- 2001
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- Publication type:
- journal article
Partial deficiency of manganese superoxide dismutase exacerbates a transgenic mouse model of amyotrophic lateral sclerosis.
- Published in:
- Annals of Neurology, 2000, v. 47, n. 4, p. 447, doi. 10.1002/1531-8249(200004)47:4<447::AID-ANA7>3.0.CO;2-R
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- Article
Huntington aggregates may not predict neuronal death in Huntington's disease.
- Published in:
- 1999
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- Publication type:
- journal article
Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis.
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- Annals of Neurology, 1997, v. 42, n. 4, p. 644, doi. 10.1002/ana.410420416
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- Publication type:
- Article
Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation.
- Published in:
- 1997
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- Publication type:
- journal article
Combination therapy with Coenzyme Q<sub>10</sub> and creatine produces additive neuroprotective effects in models of Parkinson’s and Huntington’s Diseases.
- Published in:
- Journal of Neurochemistry, 2009, v. 109, n. 5, p. 1427, doi. 10.1111/j.1471-4159.2009.06074.x
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- Publication type:
- Article
Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice.
- Published in:
- 2006
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- Correction Notice
Effects of CAG repeat length, HTT protein length and protein context on cerebral metabolism measured using magnetic resonance spectroscopy in transgenic mouse models of Huntington's disease.
- Published in:
- Journal of Neurochemistry, 2005, v. 95, n. 2, p. 553, doi. 10.1111/j.1471-4159.2005.03411.x
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- Publication type:
- Article
Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice.
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- Journal of Neurochemistry, 2005, v. 93, n. 5, p. 1087, doi. 10.1111/j.1471-4159.2005.03077.x
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- Publication type:
- Article
Cystamine increasesl-cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation.
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- Journal of Neurochemistry, 2004, v. 91, n. 2, p. 413, doi. 10.1111/j.1471-4159.2004.02726.x
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- Article
CORRECTION Sequential activation of individual caspases, and of alterations in Bcl-2 proapoptotic signals in a mouse model of Huntington's disease.
- Published in:
- 2003
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- Publication type:
- Correction Notice
Sequential activation of individual caspases, and of alterations in Bcl-2 proapoptotic signals in a mouse model of Huntington's disease.
- Published in:
- Journal of Neurochemistry, 2003, v. 87, n. 5, p. 1184, doi. 10.1046/j.1471-4159.2003.02105.x
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- Publication type:
- Article
Depletion of wild-type huntingtin in mouse models of neurologic diseases.
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- Journal of Neurochemistry, 2003, v. 87, n. 1, p. 101, doi. 10.1046/j.1471-4159.2003.01980.x
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- Publication type:
- Article
Increased survival and neuroprotective effects of BN82451 in a transgenic mouse model of Huntington's disease.
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- 2003
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- Publication type:
- Correction Notice
Increased survival and neuroprotective effects of BN82451 in a transgenic mouse model of Huntington's disease.
- Published in:
- Journal of Neurochemistry, 2003, v. 86, n. 1, p. 267, doi. 10.1046/j.1471-4159.2003.01868.x
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- Publication type:
- Article
Creatine therapy provides neuroprotection after onset of clinical symptoms in Huntington's disease transgenic mice.
- Published in:
- Journal of Neurochemistry, 2003, v. 85, n. 6, p. 1359, doi. 10.1046/j.1471-4159.2003.01706.x
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- Publication type:
- Article
Malonate and 3-Nitropropionic Acid Neurotoxicity Are Reduced in Transgenic Mice Expressing a Caspase-1 Dominant-Negative Mutant.
- Published in:
- Journal of Neurochemistry, 2000, v. 75, n. 2, p. 847, doi. 10.1046/j.1471-4159.2000.0750847.x
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- Publication type:
- Article
Nonlinear Decrease over Time in N-Acetyl Aspartate Levels in the Absence of Neuronal Loss and Increases in Glutamine and Glucose in Transgenic Huntington's Disease Mice.
- Published in:
- Journal of Neurochemistry, 2000, v. 74, n. 5, p. 2108, doi. 10.1046/j.1471-4159.2000.0742108.x
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- Publication type:
- Article
Tissue Transglutaminase Is Increased in Huntington's Disease Brain.
- Published in:
- Journal of Neurochemistry, 1999, v. 73, n. 5, p. 2018, doi. 10.1046/j.1471-4159.1999.02018.x
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- Article
Mice Deficient in Group IV Cytosolic Phospholipase A<sub>2</sub> Are Resistant to MPTP Neurotoxicity.
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- Journal of Neurochemistry, 1998, v. 71, n. 6, p. 2634, doi. 10.1046/j.1471-4159.1998.71062634.x
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- Publication type:
- Article