Works by Fernandes, João Paulo S.

Results: 15

The Novel H4R Antagonist 1-[(5-Chloro-2,3-Dihydro-1-Benzofuran-2-Yl)Methyl]-4-Methyl-Piperazine (LINS01007) Attenuates Several Symptoms in Murine Allergic Asthma.

Published in:

Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2021, v. 55, n. 6, p. 1163, doi. 10.33594/000000307

By:

Balbino, Aleksandro M.;
Lima, Leandro J. S.;
Fernandes, Gustavo A. B.;
Corrêa, Michele F.;
Gomes, Eliane;
Landgraf, Maristella A.;
Fernandes, João Paulo S.;
Landgraf, Richardt G.

Publication type:

Article

The Novel H4R Antagonist 1-[(5-Chloro- 2,3-Dihydro-1-Benzofuran-2-Yl)Methyl]-4- Methyl-Piperazine (LINS01007) Attenuates Several Symptoms in Murine Allergic Asthma.

Published in:

Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2020, v. 54, n. 6, p. 1163, doi. 10.33594/000000307

By:

Balbino, Aleksandro M.;
Lima, Leandro J. S.;
Fernandes, Gustavo A. B.;
Corrêa, Michele F.;
Gomes, Eliane;
Landgraf, Maristella A.;
Fernandes, João Paulo S.;
Landgraf, Richardt G.

Publication type:

Article

Esterification of p -Coumaric Acid Improves the Control over Melanoma Cell Growth.

Published in:

Biomedicines, 2023, v. 11, n. 1, p. 196, doi. 10.3390/biomedicines11010196

By:

Carmo-Martins, Joana I.;
Gonzatti, Michelangelo B.;
Varela, Marina T.;
Sousa, Maria Eduarda P.;
Costa, Lucas V. S.;
Rodrigues, Elaine Guadelupe;
Fernandes, João Paulo S.;
Keller, Alexandre C.

Publication type:

Article

Molecular modeling and QSAR studies of a set of indole and benzimidazole derivatives as H receptor antagonists.

Published in:

Journal of Molecular Modeling, 2011, v. 17, n. 5, p. 921, doi. 10.1007/s00894-010-0779-4

By:

Fernandes, João Paulo S.;
Pasqualoto, Kerly Fernanda M.;
Ferreira, Elizabeth I.;
Brandt, Carlos A.

Publication type:

Article

Benzylidene-carbonyl compounds are active against itraconazole-susceptible and itraconazole-resistant Sporothrix brasiliensis.

Published in:

Folia Microbiologica, 2020, v. 65, n. 6, p. 1033, doi. 10.1007/s12223-020-00814-4

By:

Waller, Stefanie Bressan;
Cleff, Marlete Brum;
Ripoll, Márcia Kutscher;
Meireles, Mário Carlos Araújo;
Varela, Marina Themoteo;
Fernandes, João Paulo dos S.

Publication type:

Article

Synthetic Analogues of Gibbilimbol B Induce Bioenergetic Damage and Calcium Imbalance in Trypanosoma cruzi.

Published in:

Life (2075-1729), 2023, v. 13, n. 3, p. 663, doi. 10.3390/life13030663

By:

Amaral, Maiara;
Varela, Marina T.;
Kant, Ravi;
Christodoulides, Myron;
Fernandes, João Paulo S.;
Tempone, Andre G.

Publication type:

Article

Profiling of LINS01 compounds at human dopamine D2 and D3 receptors.

Published in:

Journal of Chemical Sciences, 2020, v. 132, n. 1, p. 1, doi. 10.1007/s12039-019-1694-6

By:

Corrêa, Michelle F;
Reiner, David;
Fernandes, Gustavo A B;
Varela, Marina T;
Aranha, Cecília M S Q;
Stark, Holger;
Fernandes, João Paulo S

Publication type:

Article

Improving the drug-likeness of inspiring natural products - evaluation of the antiparasitic activity against Trypanosoma cruzi through semi-synthetic and simplified analogues of licarin A.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-62352-w

By:

Morais, Thiago R.;
Conserva, Geanne A. Alves;
Varela, Marina T.;
Costa-Silva, Thais A.;
Thevenard, Fernanda;
Ponci, Vitor;
Fortuna, Ana;
Falcão, Amílcar C.;
Tempone, Andre G.;
Fernandes, João Paulo S.;
Lago, João Henrique G.

Publication type:

Article

Neurotoxicity Assessment of 1-[(2,3-Dihydro-1-Benzofuran-2-yl)Methyl]Piperazine (LINS01 Series) Derivatives and their Protective Effect on Cocaine-Induced Neurotoxicity Model in SH-SY5Y Cell Culture.

Published in:

Neurotoxicity Research, 2022, v. 40, n. 6, p. 1653, doi. 10.1007/s12640-022-00601-8

By:

dos Santos, Laísa Aliandro;
dos Santos, Gabriela Salles;
Fernandes, Gustavo Ariel Borges;
Corrêa, Michelle Fidelis;
de Faria Almeida, Carolina Aparecida;
Fernandes, Liliam;
Marcourakis, Tania;
Fernandes, João Paulo S.;
Garcia, Raphael Caio Tamborelli

Publication type:

Article

Histamine research advancements in the second year of the COVID-19 pandemic: report of the European Histamine Research Society (EHRS).

Published in:

Inflammation Research, 2022, v. 71, n. 7/8, p. 995, doi. 10.1007/s00011-022-01589-9

By:

Obara, Ilona;
Fernandes, João Paulo S.;
Tiligada, Ekaterini

Publication type:

Article

Metabolite profile of Nectandra oppositifolia Nees & Mart. and assessment of antitrypanosomal activity of bioactive compounds through efficiency analyses.

Published in:

PLoS ONE, 2021, v. 16, n. 2, p. 1, doi. 10.1371/journal.pone.0247334

By:

Alves Conserva, Geanne A.;
Quirós-Guerrero, Luis M.;
Costa-Silva, Thais A.;
Marcourt, Laurence;
Pinto, Erika G.;
Tempone, Andre G.;
Fernandes, João Paulo S.;
Wolfender, Jean-Luc;
Queiroz, Emerson F.;
Lago, João Henrique G.

Publication type:

Article

Evaluation of the histamine H3 receptor antagonists from LINS01 series as cholinesterases inhibitors: Enzymatic and modeling studies.

Published in:

Chemical Biology & Drug Design, 2022, v. 100, n. 5, p. 722, doi. 10.1111/cbdd.14139

By:

Lopes, Flávia B.;
Aranha, Cecília M. S. Q.;
Corrêa, Michelle F.;
Fernandes, Gustavo A. B.;
Okamoto, Debora N.;
Simões, Leonardo P. M.;
Junior, Nailton M. N.;
Fernandes, João Paulo S.

Publication type:

Article

Bioisosteric modification on benzylidene‐carbonyl compounds improved the drug‐likeness and maintained the antifungal activity against Sporothrix brasiliensis.

Published in:

Chemical Biology & Drug Design, 2022, v. 99, n. 3, p. 391, doi. 10.1111/cbdd.13994

By:

Waller, Stefanie Bressan;
Cleff, Marlete Brum;
Ripoll, Márcia Kutscher;
Meireles, Mário Carlos Araújo;
Ferrarini, Márcio;
Varela, Marina Themoteo;
Fernandes, João Paulo S.

Publication type:

Article

Histamine H3 receptor and cholinesterases as synergistic targets for cognitive decline: Strategies to the rational design of multitarget ligands.

Published in:

2021

By:

Lopes, Flávia B.;
Aranha, Cecília M. S. Q.;
Fernandes, João Paulo S.

Publication type:

Literature Review

New alkenyl derivative from Piper malacophyllum and analogues: Antiparasitic activity against Trypanosoma cruzi and Leishmania infantum.

Published in:

Chemical Biology & Drug Design, 2017, v. 90, n. 5, p. 1007, doi. 10.1111/cbdd.12986

By:

Varela, Marina T.;
Lima, Marta L.;
Galuppo, Mariana K.;
Tempone, Andre G.;
Oliveira, Alberto;
Lago, João Henrique G.;
Fernandes, João Paulo S.

Publication type:

Article

Works by Fernandes, João Paulo S.

The Novel H<sub>4</sub>R Antagonist 1-[(5-Chloro-2,3-Dihydro-1-Benzofuran-2-Yl)Methyl]-4-Methyl-Piperazine (LINS01007) Attenuates Several Symptoms in Murine Allergic Asthma.

The Novel H<sub>4</sub>R Antagonist 1-[(5-Chloro- 2,3-Dihydro-1-Benzofuran-2-Yl)Methyl]-4- Methyl-Piperazine (LINS01007) Attenuates Several Symptoms in Murine Allergic Asthma.

Esterification of p -Coumaric Acid Improves the Control over Melanoma Cell Growth.

Molecular modeling and QSAR studies of a set of indole and benzimidazole derivatives as H receptor antagonists.

Benzylidene-carbonyl compounds are active against itraconazole-susceptible and itraconazole-resistant Sporothrix brasiliensis.

Synthetic Analogues of Gibbilimbol B Induce Bioenergetic Damage and Calcium Imbalance in Trypanosoma cruzi.

Profiling of LINS01 compounds at human dopamine D2 and D3 receptors.

Improving the drug-likeness of inspiring natural products - evaluation of the antiparasitic activity against Trypanosoma cruzi through semi-synthetic and simplified analogues of licarin A.

Neurotoxicity Assessment of 1-[(2,3-Dihydro-1-Benzofuran-2-yl)Methyl]Piperazine (LINS01 Series) Derivatives and their Protective Effect on Cocaine-Induced Neurotoxicity Model in SH-SY5Y Cell Culture.

Histamine research advancements in the second year of the COVID-19 pandemic: report of the European Histamine Research Society (EHRS).

Metabolite profile of Nectandra oppositifolia Nees & Mart. and assessment of antitrypanosomal activity of bioactive compounds through efficiency analyses.

Evaluation of the histamine H<sub>3</sub> receptor antagonists from LINS01 series as cholinesterases inhibitors: Enzymatic and modeling studies.

Bioisosteric modification on benzylidene‐carbonyl compounds improved the drug‐likeness and maintained the antifungal activity against Sporothrix brasiliensis.

Histamine H<sub>3</sub> receptor and cholinesterases as synergistic targets for cognitive decline: Strategies to the rational design of multitarget ligands.

New alkenyl derivative from Piper malacophyllum and analogues: Antiparasitic activity against Trypanosoma cruzi and Leishmania infantum.