Works by Fernández-Quintero, Monica L.

Results: 44

Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38509-2

By:

Martin, Gregory M.;
Fernández-Quintero, Monica L.;
Lee, Wen-Hsin;
Pholcharee, Tossapol;
Eshun-Wilson, Lisa;
Liedl, Klaus R.;
Pancera, Marie;
Seder, Robert A.;
Wilson, Ian A.;
Ward, Andrew B.

Publication type:

Article

Antibody humanization—the Influence of the antibody framework on the CDR-H3 loop ensemble in solution.

Published in:

PEDS: Protein Engineering, Design & Selection, 2019, v. 32, n. 9, p. 411, doi. 10.1093/protein/gzaa004

By:

Fernández-Quintero, Monica L;
Heiss, Martin C;
Liedl, Klaus R

Publication type:

Article

On the humanization of VHHs: Prospective case studies, experimental and computational characterization of structural determinants for functionality.

Published in:

Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 11, p. 1, doi. 10.1002/pro.5176

By:

Fernández‐Quintero, Monica L.;
Guarnera, Enrico;
Musil, Djordje;
Pekar, Lukas;
Sellmann, Carolin;
Freire, Filipe;
Sousa, Raquel L.;
Santos, Sandra P.;
Freitas, Micael C.;
Bandeiras, Tiago M.;
Silva, Margarida M. S.;
Loeffler, Johannes R.;
Ward, Andrew B.;
Harwardt, Julia;
Zielonka, Stefan;
Evers, Andreas

Publication type:

Article

Fit‐for‐purpose heterodivalent single‐domain antibody for gastrointestinal targeting of toxin B from Clostridium difficile.

Published in:

Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 7, p. 1, doi. 10.1002/pro.5035

By:

Rodriguez Rodriguez, Everardo R.;
Nordvang, Rune Thorbjørn;
Petersson, Marcus;
Rendsvig, Jakob Kræmmer Haar;
Arendrup, Emma Wenzel;
Fernández Quintero, Monica L.;
Jenkins, Timothy P.;
Laustsen, Andreas H.;
Thrane, Sandra Wingaard

Publication type:

Article

Phage display assisted discovery of a pH‐dependent anti‐α‐cobratoxin antibody from a natural variable domain library.

Published in:

Protein Science: A Publication of the Protein Society, 2023, v. 32, n. 12, p. 1, doi. 10.1002/pro.4821

By:

Tulika, Tulika;
Pedersen, Rasmus W.;
Rimbault, Charlotte;
Ahmadi, Shirin;
Rivera‐de‐Torre, Esperanza;
Fernández‐Quintero, Monica L.;
Loeffler, Johannes R.;
Bohn, Markus‐Frederik;
Ljungars, Anne;
Ledsgaard, Line;
Voldborg, Bjørn G.;
Ruso‐Julve, Fulgencio;
Andersen, Jan Terje;
Laustsen, Andreas H.

Publication type:

Article

Pore mutation N617D in the skeletal muscle DHPR blocks Ca2+ influx due to atypical high-affinity Ca2+ binding.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.63435

By:

Dayal, Anamika;
Fernández-Quintero, Monica L.;
Liedl, Klaus R.;
Grabner, Manfred

Publication type:

Article

Structural determinants of voltage-gating properties in calcium channels.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.64087

By:

Fernández-Quintero, Monica L.;
Ghaleb, Yousra El;
Tuluc, Petronel;
Campiglio, Marta;
Liedl, Klaus R.;
Flucher, Bernhard E.

Publication type:

Article

The influence of antibody humanization on shark variable domain (VNAR) binding site ensembles.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.953917

By:

Fernández-Quintero, Monica L.;
Fischer, Anna-Lena M.;
Kokot, Janik;
Waibl, Franz;
Seidler, Clarissa A.;
Liedl, Klaus R.

Publication type:

Article

Structural mechanism of Fab domain dissociation as a measure of interface stability.

Published in:

Journal of Computer-Aided Molecular Design, 2023, v. 37, n. 4, p. 201, doi. 10.1007/s10822-023-00501-9

By:

Pomarici, Nancy D.;
Waibl, Franz;
Quoika, Patrick K.;
Bujotzek, Alexander;
Georges, Guy;
Fernández-Quintero, Monica L.;
Liedl, Klaus R.

Publication type:

Article

Explicit solvation thermodynamics in ionic solution: extending grid inhomogeneous solvation theory to solvation free energy of salt–water mixtures.

Published in:

Journal of Computer-Aided Molecular Design, 2022, v. 36, n. 2, p. 101, doi. 10.1007/s10822-021-00429-y

By:

Waibl, Franz;
Kraml, Johannes;
Fernández-Quintero, Monica L.;
Loeffler, Johannes R.;
Liedl, Klaus R.

Publication type:

Article

Structural Basis of the Immunological Cross-Reactivity between Kiwi and Birch Pollen.

Published in:

Foods, 2023, v. 12, n. 21, p. 3939, doi. 10.3390/foods12213939

By:

Zeindl, Ricarda;
Franzmann, Annika L.;
Fernández-Quintero, Monica L.;
Seidler, Clarissa A.;
Hoerschinger, Valentin J.;
Liedl, Klaus R.;
Tollinger, Martin

Publication type:

Article

T-Cell Receptor CDR3 Loop Conformations in Solution Shift the Relative Vα-Vβ Domain Distributions.

Published in:

Frontiers in Immunology, 2020, v. 11, p. 1, doi. 10.3389/fimmu.2020.01440

By:

Fernández-Quintero, Monica L.;
Pomarici, Nancy D.;
Loeffler, Johannes R.;
Seidler, Clarissa A.;
Liedl, Klaus R.

Publication type:

Article

Germline de novo variant F747S extends the phenotypic spectrum of CACNA1D Ca2+ channelopathies.

Published in:

Human Molecular Genetics, 2023, v. 32, n. 5, p. 847, doi. 10.1093/hmg/ddac248

By:

Török, Ferenc;
Tezcan, Kamer;
Filippini, Ludovica;
Fernández-Quintero, Monica L;
Zanetti, Lucia;
Liedl, Klaus R;
Drexel, Raphaela S;
Striessnig, Jörg;
Ortner, Nadine J

Publication type:

Article

Structurally convergent antibodies derived from different vaccine strategies target the influenza virus HA anchor epitope with a subset of VH3 and VK3 genes.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56496-4

By:

Lin, Ting-Hui;
Lee, Chang-Chun David;
Fernández-Quintero, Monica L.;
Ferguson, James A.;
Han, Julianna;
Zhu, Xueyong;
Yu, Wenli;
Guthmiller, Jenna J.;
Krammer, Florian;
Wilson, Patrick C.;
Ward, Andrew B.;
Wilson, Ian A.

Publication type:

Article

A single mutation in dairy cow-associated H5N1 viruses increases receptor binding breadth.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-54934-3

By:

Good, Marina R.;
Fernández-Quintero, Monica L.;
Ji, Wei;
Rodriguez, Alesandra J.;
Han, Julianna;
Ward, Andrew B.;
Guthmiller, Jenna J.

Publication type:

Article

Defining the cross-reactivity between peanut allergens Ara h 2 and Ara h 6 using monoclonal antibodies.

Published in:

Clinical & Experimental Immunology, 2024, v. 216, n. 1, p. 25, doi. 10.1093/cei/uxae005

By:

Marini-Rapoport, Orlee;
Fernández-Quintero, Monica L;
Keswani, Tarun;
Zong, Guangning;
Shim, Jane;
Pedersen, Lars C;
Mueller, Geoffrey A;
Patil, Sarita U

Publication type:

Article

T-Cell Receptor Variable β Domains Rigidify During Affinity Maturation.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-61433-0

By:

Fernández-Quintero, Monica L.;
Seidler, Clarissa A.;
Liedl, Klaus R.

Publication type:

Article

Structure and Dynamics Guiding Design of Antibody Therapeutics and Vaccines.

Published in:

Antibodies (2073-4468), 2023, v. 12, n. 4, p. 67, doi. 10.3390/antib12040067

By:

Fernández-Quintero, Monica L.;
Pomarici, Nancy D.;
Fischer, Anna-Lena M.;
Hoerschinger, Valentin J.;
Kroell, Katharina B.;
Riccabona, Jakob R.;
Kamenik, Anna S.;
Loeffler, Johannes R.;
Ferguson, James A.;
Perrett, Hailee R.;
Liedl, Klaus R.;
Han, Julianna;
Ward, Andrew B.

Publication type:

Article

Distinct oligomeric assemblies of STING induced by non-nucleotide agonists.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58641-5

By:

Gharpure, Anant;
Sulpizio, Ariana;
Loeffler, Johannes R.;
Fernández-Quintero, Monica L.;
Tran, Andy S.;
Lairson, Luke L.;
Ward, Andrew B.

Publication type:

Article

Challenges in antibody structure prediction.

Published in:

mAbs (1942-0862), 2023, v. 15, n. 1, p. 1, doi. 10.1080/19420862.2023.2175319

By:

Fernández-Quintero, Monica L.;
Kokot, Janik;
Waibl, Franz;
Fischer, Anna-Lena M.;
Quoika, Patrick K.;
Deane, Charlotte M.;
Liedl, Klaus R.

Publication type:

Article

Assessing developability early in the discovery process for novel biologics.

Published in:

mAbs (1942-0862), 2023, v. 15, n. 1, p. 1, doi. 10.1080/19420862.2023.2171248

By:

Fernández-Quintero, Monica L.;
Ljungars, Anne;
Waibl, Franz;
Greiff, Victor;
Andersen, Jan Terje;
Gjølberg, Torleif T.;
Jenkins, Timothy P.;
Voldborg, Bjørn Gunnar;
Grav, Lise Marie;
Kumar, Sandeep;
Georges, Guy;
Kettenberger, Hubert;
Liedl, Klaus R.;
Tessier, Peter M.;
McCafferty, John;
Laustsen, Andreas H.

Publication type:

Article

CDR loop interactions can determine heavy and light chain pairing preferences in bispecific antibodies.

Published in:

2022

By:

Fernández-Quintero, Monica L.;
Kroell, Katharina B.;
Grunewald, Lukas J.;
Fischer, Anna-Lena M.;
Riccabona, Jakob R.;
Liedl, Klaus R.

Publication type:

Report

Ensembles in solution as a new paradigm for antibody structure prediction and design.

Published in:

mAbs (1942-0862), 2021, v. 13, n. 1, p. 1, doi. 10.1080/19420862.2021.1923122

By:

Fernández-Quintero, Monica L.;
Georges, Guy;
Varga, Janos M.;
Liedl, Klaus R.

Publication type:

Article

Antibody CDR loops as ensembles in solution vs. canonical clusters from X-ray structures.

Published in:

2020

By:

Fernández-Quintero, Monica L.;
Heiss, Martin C.;
Pomarici, Nancy D.;
Math, Barbara A.;
Liedl, Klaus R.

Publication type:

Report

CDR-H3 loop ensemble in solution – conformational selection upon antibody binding.

Published in:

2019

By:

Fernández-Quintero, Monica L.;
Kraml, Johannes;
Georges, Guy;
Liedl, Klaus R.

Publication type:

Report

Essential role of a conserved aspartate for the enzymatic activity of plasmanylethanolamine desaturase.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 4, p. 1, doi. 10.1007/s00018-022-04238-w

By:

Werner, Ernst R.;
Fernández-Quintero, Monica L.;
Hulo, Nicolas;
Golderer, Georg;
Sailer, Sabrina;
Lackner, Katharina;
Werner-Felmayer, Gabriele;
Liedl, Klaus R.;
Watschinger, Katrin

Publication type:

Article

Allergenicity and Conformational Diversity of Allergens.

Published in:

Allergies (2313-5786), 2024, v. 4, n. 1, p. 1, doi. 10.3390/allergies4010001

By:

Seidler, Clarissa A.;
Zeindl, Ricarda;
Fernández-Quintero, Monica L.;
Tollinger, Martin;
Liedl, Klaus R.

Publication type:

Article

AIntibody: an experimentally validated in silico antibody discovery design challenge.

Published in:

2024

By:

Erasmus, M. Frank;
Spector, Laura;
Ferrara, Fortunato;
DiNiro, Roberto;
Pohl, Thomas J.;
Perea-Schmittle, Katheryn;
Wang, Wei;
Tessier, Peter M.;
Richardson, Crystal;
Turner, Laure;
Kumar, Sumit;
Bedinger, Daniel;
Sormanni, Pietro;
Fernández-Quintero, Monica L.;
Ward, Andrew B.;
Loeffler, Johannes R.;
Swanson, Olivia M.;
Deane, Charlotte M.;
Raybould, Matthew I. J.;
Evers, Andreas

Publication type:

Letter

Characterization of two pathological gating-charge substitutions in Cav1.4 L-type calcium channels.

Published in:

Channels (19336950), 2023, v. 17, n. 1, p. 1, doi. 10.1080/19336950.2023.2192360

By:

Heigl, Thomas;
Netzer, Michael A.;
Zanetti, Lucia;
Ganglberger, Matthias;
Fernández-Quintero, Monica L.;
Koschak, Alexandra

Publication type:

Article

The Structural Flexibility of PR-10 Food Allergens.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8252, doi. 10.3390/ijms23158252

By:

Führer, Sebastian;
Unterhauser, Jana;
Zeindl, Ricarda;
Eidelpes, Reiner;
Fernández-Quintero, Monica L.;
Liedl, Klaus R.;
Tollinger, Martin

Publication type:

Article

Nanobody Paratope Ensembles in Solution Characterized by MD Simulations and NMR.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 10, p. 5419, doi. 10.3390/ijms23105419

By:

Fernández-Quintero, Monica L.;
DeRose, Eugene F.;
Gabel, Scott A.;
Mueller, Geoffrey A.;
Liedl, Klaus R.

Publication type:

Article

Antibodies exhibit multiple paratope states influencing VH–VL domain orientations.

Published in:

Communications Biology, 2020, v. 3, n. 1, p. N.PAG, doi. 10.1038/s42003-020-01319-z

By:

Fernández-Quintero, Monica L.;
Pomarici, Nancy D.;
Math, Barbara A.;
Kroell, Katharina B.;
Waibl, Franz;
Bujotzek, Alexander;
Georges, Guy;
Liedl, Klaus R.

Publication type:

Article

VH‐VL interdomain dynamics observed by computer simulations and NMR.

Published in:

Proteins, 2020, v. 88, n. 7, p. 830, doi. 10.1002/prot.25872

By:

Fernández‐Quintero, Monica L.;
Hoerschinger, Valentin J.;
Lamp, Leonida M.;
Bujotzek, Alexander;
Georges, Guy;
Liedl, Klaus R.

Publication type:

Article

High Intrinsic Oncogenic Potential in the Myc-Box-Deficient Hydra Myc3 Protein.

Published in:

Cells (2073-4409), 2023, v. 12, n. 9, p. 1265, doi. 10.3390/cells12091265

By:

Lechable, Marion;
Tang, Xuechen;
Siebert, Stefan;
Feldbacher, Angelika;
Fernández-Quintero, Monica L.;
Breuker, Kathrin;
Juliano, Celina E.;
Liedl, Klaus R.;
Hobmayer, Bert;
Hartl, Markus

Publication type:

Article

CACNA1I gain-of-function mutations differentially affect channel gating and cause neurodevelopmental disorders.

Published in:

2021

By:

Ghaleb, Yousra El;
Schneeberger, Pauline E;
Fernández-Quintero, Monica L;
Geisler, Stefanie M;
Pelizzari, Simone;
Polstra, Abeltje M;
Hagen, Johanna M van;
Denecke, Jonas;
Campiglio, Marta;
Liedl, Klaus R;
Stevens, Cathy A;
Person, Richard E;
Rentas, Stefan;
Marsh, Eric D;
Conlin, Laura K;
Tuluc, Petronel;
Kutsche, Kerstin;
Flucher, Bernhard E;
El Ghaleb, Yousra;
van Hagen, Johanna M

Publication type:

journal article

Bispecific antibodies—effects of point mutations on CH3-CH3 interface stability.

Published in:

PEDS: Protein Engineering, Design & Selection, 2022, v. 35, p. 1, doi. 10.1093/protein/gzac012

By:

Pomarici, Nancy D;
Fernández-Quintero, Monica L;
Quoika, Patrick K;
Waibl, Franz;
Bujotzek, Alexander;
Georges, Guy;
Liedl, Klaus R

Publication type:

Article

Conformational selection of allergen-antibody complexes—surface plasticity of paratopes and epitopes.

Published in:

PEDS: Protein Engineering, Design & Selection, 2019, v. 32, n. 11, p. 513, doi. 10.1093/protein/gzaa014

By:

Fernández-Quintero, Monica L;
Loeffler, Johannes R;
Waibl, Franz;
Kamenik, Anna S;
Hofer, Florian;
Liedl, Klaus R

Publication type:

Article

Evolution of the Immunoglobulin Isotypes—Variations of Biophysical Properties among Animal Classes.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 5, p. 801, doi. 10.3390/biom13050801

By:

Pomarici, Nancy D.;
Cacciato, Roberta;
Kokot, Janik;
Fernández-Quintero, Monica L.;
Liedl, Klaus R.

Publication type:

Article

Structural Characterization of Nanobodies during Germline Maturation.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 2, p. 380, doi. 10.3390/biom13020380

By:

Seidler, Clarissa A.;
Kokot, Janik;
Fernández-Quintero, Monica L.;
Liedl, Klaus R.

Publication type:

Article

Germline-Dependent Antibody Paratope States and Pairing Specific VH-VL Interface Dynamics.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.675655

By:

Fernández-Quintero, Monica L.;
Kroell, Katharina B.;
Bacher, Lisa M.;
Loeffler, Johannes R.;
Quoika, Patrick K.;
Georges, Guy;
Bujotzek, Alexander;
Kettenberger, Hubert;
Liedl, Klaus R.

Publication type:

Article

Mutation of Framework Residue H71 Results in Different Antibody Paratope States in Solution.

Published in:

Frontiers in Immunology, 2021, p. N.PAG, doi. 10.3389/fimmu.2021.630034

By:

Fernández-Quintero, Monica L.;
Kroell, Katharina B.;
Hofer, Florian;
Riccabona, Jakob R.;
Liedl, Klaus R.

Publication type:

Article

Inactivation induced by pathogenic Cav1.3 L‐type Ca2+‐channel variants enhances sensitivity for dihydropyridine Ca2+ channel blockers.

Published in:

British Journal of Pharmacology, 2025, v. 182, n. 1, p. 181, doi. 10.1111/bph.17357

By:

Török, Ferenc;
Salamon, Sarah;
Ortner, Nadine J.;
Fernández‐Quintero, Monica L.;
Matthes, Jan;
Striessnig, Jörg

Publication type:

Article

Cover Image, Volume 91, Issue 9.

Published in:

Proteins, 2023, v. 91, n. 9, p. C1, doi. 10.1002/prot.26572

By:

Math, Barbara A.;
Waibl, Franz;
Lamp, Leonida M.;
Fernández‐Quintero, Monica L.;
Liedl, Klaus R.

Publication type:

Article

Cross‐linking disulfide bonds govern solution structures of diabodies.

Published in:

Proteins, 2023, v. 91, n. 9, p. 1316, doi. 10.1002/prot.26509

By:

Math, Barbara A.;
Waibl, Franz;
Lamp, Leonida M.;
Fernández‐Quintero, Monica L.;
Liedl, Klaus R.

Publication type:

Article