Works by Fenyi, Alexis

Results: 10

Sequential or Simultaneous Injection of Preformed Fibrils and AAV Overexpression of Alpha-Synuclein Are Equipotent in Producing Relevant Pathology and Behavioral Deficits.

Published in:

Journal of Parkinson's Disease, 2022, v. 12, n. 4, p. 1133, doi. 10.3233/JPD-212555

By:

Negrini, Matilde;
Tomasello, Giuseppe;
Davidsson, Marcus;
Fenyi, Alexis;
Adant, Cécile;
Hauser, Swantje;
Espa, Elena;
Gubinelli, Francesco;
Manfredsson, Fredric P.;
Melki, Ronald;
Heuer, Andreas

Publication type:

Article

Neither alpha-synuclein fibril strain nor host murine genotype influences seeding efficacy.

Published in:

NPJ Parkinson's Disease, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41531-024-00679-1

By:

Walton, Sara;
Fenyi, Alexis;
Tittle, Tyler;
Sidransky, Ellen;
Pal, Gian;
Choi, Solji;
Melki, Ronald;
Killinger, Bryan A.;
Kordower, Jeffrey H.

Publication type:

Article

Targeting amyotrophic lateral sclerosis by neutralizing seeding-competent TDP-43 in CSF.

Published in:

Brain Communications, 2023, v. 5, n. 6, p. 1, doi. 10.1093/braincomms/fcad306

By:

Audrain, Mickael;
Egesipe, Anne-Laure;
Tentillier, Noémie;
Font, Laure;
Ratnam, Monisha;
Mottier, Lorene;
Clavel, Mathieu;
Le Roux-Bourdieu, Morgan;
Fenyi, Alexis;
Ollier, Romain;
Chevalier, Elodie;
Guilhot, Florence;
Fuchs, Aline;
Piorkowska, Kasia;
Carlyle, Becky;
Arnold, Steven E.;
Berry, James D.;
Luthi-Carter, Ruth;
Adolfsson, Oskar;
Pfeifer, Andrea

Publication type:

Article

A new class of neurodegenerative disease‐fighting drugs: morADC (Morphomer®‐ antibody drug conjugates).

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S8, p. 1, doi. 10.1002/alz.091477

By:

Nampally, Sreenivasachary;
Adolfsson, Oskar;
Martin, Camille;
Ollier, Romain;
Menant, Sebastien;
Tsika, Elpida;
Fenyi, Alexis;
Ait‐Bouziad, Nadine;
Aeschbach, Lorene;
Pautet, Sylvain;
Fuchs, Aline;
Ribas, David;
Derouazi, Madiha;
Pfeifer, Andrea;
Kosco‐Vilbois, Marie

Publication type:

Article

Parkinson's disease-derived α-synuclein assemblies combined with chronic-type inflammatory cues promote a neurotoxic microglial phenotype.

Published in:

Journal of Neuroinflammation, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12974-024-03043-5

By:

Yildirim-Balatan, Cansu;
Fenyi, Alexis;
Besnault, Pierre;
Gomez, Lina;
Sepulveda-Diaz, Julia E.;
Michel, Patrick P.;
Melki, Ronald;
Hunot, Stéphane

Publication type:

Article

Phenotypic manifestation of α-synuclein strains derived from Parkinson's disease and multiple system atrophy in human dopaminergic neurons.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23682-z

By:

Tanudjojo, Benedict;
Shaikh, Samiha S.;
Fenyi, Alexis;
Bousset, Luc;
Agarwal, Devika;
Marsh, Jade;
Zois, Christos;
Heman-Ackah, Sabrina;
Fischer, Roman;
Sims, David;
Melki, Ronald;
Tofaris, George K.

Publication type:

Article

Aptamer binding footprints discriminate α-synuclein fibrillar polymorphs from different synucleinopathies.

Published in:

Nucleic Acids Research, 2024, v. 52, n. 14, p. 8072, doi. 10.1093/nar/gkae544

By:

Bouvier-Müller, Alix;
Fourmy, Deborah;
Fenyi, Alexis;
Bousset, Luc;
Melki, Ronald;
Ducongé, Frédéric

Publication type:

Article

Seeding Propensity and Characteristics of Pathogenic αSyn Assemblies in Formalin-Fixed Human Tissue from the Enteric Nervous System, Olfactory Bulb, and Brainstem in Cases Staged for Parkinson's Disease.

Published in:

Cells (2073-4409), 2021, v. 10, n. 1, p. 139, doi. 10.3390/cells10010139

By:

Fenyi, Alexis;
Duyckaerts, Charles;
Bousset, Luc;
Braak, Heiko;
Tredici, Kelly Del;
Melki, Ronald;
on behalf of the Brainbank Neuro-CEB Neuropathology Network

Publication type:

Article

The structural differences between patient-derived α-synuclein strains dictate characteristics of Parkinson's disease, multiple system atrophy and dementia with Lewy bodies.

Published in:

Acta Neuropathologica, 2020, v. 139, n. 6, p. 977, doi. 10.1007/s00401-020-02157-3

By:

Van der Perren, Anke;
Gelders, Géraldine;
Fenyi, Alexis;
Bousset, Luc;
Brito, Filipa;
Peelaerts, Wouter;
Van den Haute, Chris;
Gentleman, Steve;
Melki, Ronald;
Baekelandt, Veerle

Publication type:

Article

Detection of antibodies against the huntingtin protein in human plasma.

Published in:

Cellular & Molecular Life Sciences, 2023, v. 80, n. 2, p. 1, doi. 10.1007/s00018-023-04687-x

By:

Denis, Hélèna L.;
Alpaugh, Melanie;
Alvarez, Claudia P.;
Fenyi, Alexis;
Barker, Roger A.;
Chouinard, Sylvain;
Arrowsmith, Cheryl H.;
Melki, Ronald;
Labib, Richard;
Harding, Rachel J.;
Cicchetti, Francesca

Publication type:

Article