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The Brucella melitensis M5-90 phosphoglucomutase (PGM) mutant is attenuated and confers protection against wild-type challenge in BALB/c mice.
Published in:
World Journal of Microbiology & Biotechnology, 2016, v. 32, n. 4, p. 1, doi. 10.1007/s11274-016-2015-6
By:
- Zhang, Yu;
- Li, Tiansen;
- Zhang, Jing;
- Li, Zhiqiang;
- Zhang, Yan;
- Wang, Zhen;
- Feng, Hanping;
- Wang, Yuanzhi;
- Chen, Chuangfu;
- Zhang, Hui
Publication type:
Article
Correction: Selection and characterization of ultrahigh potency designed ankyrin repeat protein inhibitors of C. difficile toxin B.
Published in:
PLoS Biology, 2019, v. 17, n. 10, p. 1, doi. 10.1371/journal.pbio.3000514
By:
- Simeon, Rudo;
- Jiang, Mengqiu;
- Chamoun-Emanuelli, Ana M.;
- Yu, Hua;
- Zhang, Yongrong;
- Meng, Ran;
- Peng, Zeyu;
- Jakana, Joanita;
- Zhang, Junjie;
- Feng, Hanping;
- Chen, Zhilei
Publication type:
Article
Selection and characterization of ultrahigh potency designed ankyrin repeat protein inhibitors of C. difficile toxin B.
Published in:
PLoS Biology, 2019, v. 17, n. 6, p. 1, doi. 10.1371/journal.pbio.3000311
By:
- Simeon, Rudo;
- Jiang, Mengqiu;
- Chamoun-Emanuelli, Ana M.;
- Yu, Hua;
- Zhang, Yongrong;
- Meng, Ran;
- Peng, Zeyu;
- Jakana, Joanita;
- Zhang, Junjie;
- Feng, Hanping;
- Chen, Zhilei
Publication type:
Article
Retargeting Clostridium difficile Toxin B to Neuronal Cells as a Potential Vehicle for Cytosolic Delivery of Therapeutic Biomolecules to Treat Botulism.
Published in:
Journal of Toxicology, 2012, p. 1, doi. 10.1155/2012/760142
By:
- Krautz-Peterson, Greice;
- Zhang, Yongrong;
- Chen, Kevin;
- Oyler, George A.;
- Feng, Hanping;
- Shoemaker, Charles B.
Publication type:
Article
A Multiparticulate Delivery System for Potential Colonic Targeting Using Bovine Serum Albumin as a Model Protein.
Published in:
Pharmaceutical Research, 2017, v. 34, n. 12, p. 2663, doi. 10.1007/s11095-017-2237-9
By:
- Jiang, Bowen;
- Yu, Hua;
- Zhang, Yongrong;
- Feng, Hanping;
- Hoag, Stephen
Publication type:
Article
Host S-nitrosylation inhibits clostridial small molecule-activated glucosylating toxins.
Published in:
Nature Medicine, 2011, v. 17, n. 9, p. 1136, doi. 10.1038/nm.2405
By:
- Savidge, Tor C;
- Urvil, Petri;
- Oezguen, Numan;
- Ali, Kausar;
- Choudhury, Aproteem;
- Acharya, Vinay;
- Pinchuk, Irina;
- Torres, Alfredo G;
- English, Robert D;
- Wiktorowicz, John E;
- Loeffelholz, Michael;
- Kumar, Raj;
- Shi, Lianfa;
- Nie, Weijia;
- Braun, Werner;
- Herman, Bo;
- Hausladen, Alfred;
- Feng, Hanping;
- Stamler, Jonathan S;
- Pothoulakis, Charalabos
Publication type:
Article
Identification of Toxemia in Patients with Clostridium difficile Infection.
Published in:
PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0124235
By:
- Yu, Hua;
- Chen, Kevin;
- Wu, Jianguo;
- Yang, Zhiyong;
- Shi, Lianfa;
- Barlow, Lydia L.;
- Aronoff, David M.;
- Garey, Kevin W.;
- Savidge, Tor C.;
- von Rosenvinge, Erik C.;
- Kelly, Ciaran P.;
- Feng, Hanping
Publication type:
Article
Utility of Clostridium difficile Toxin B for Inducing Anti-Tumor Immunity.
Published in:
PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0110826
By:
- Huang, Tuxiong;
- Li, Shan;
- Li, Guangchao;
- Tian, Yuan;
- Wang, Haiying;
- Shi, Lianfa;
- Perez-Cordon, Gregorio;
- Mao, Li;
- Wang, Xiaoning;
- Wang, Jufang;
- Feng, Hanping
Publication type:
Article
A Segment of 97 Amino Acids within the Translocation Domain of <i>Clostridium difficile</i> Toxin B Is Essential for Toxicity.
Published in:
PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058634
By:
- Zhang, Yongrong;
- Shi, Lianfa;
- Li, Shan;
- Yang, Zhiyong;
- Standley, Clive;
- Yang, Zhong;
- ZhuGe, Ronghua;
- Savidge, Tor;
- Wang, Xiaoning;
- Feng, Hanping
Publication type:
Article
A Novel Multivalent, Single-Domain Antibody Targeting TcdA and TcdB Prevents Fulminant Clostridium difficile Infection in Mice.
Published in:
Journal of Infectious Diseases, 2014, v. 210, n. 6, p. 964, doi. 10.1093/infdis/jiu196
By:
- Yang, Zhiyong;
- Schmidt, Diane;
- Liu, Weilong;
- Li, Shan;
- Shi, Lianfa;
- Sheng, Jinliang;
- Chen, Kevin;
- Yu, Hua;
- Tremblay, Jacqueline M.;
- Chen, Xinhua;
- Piepenbrink, Kurt H.;
- Sundberg, Eric J.;
- Kelly, Ciaran P.;
- Bai, Guang;
- Shoemaker, Charles B.;
- Feng, Hanping
Publication type:
Article
Systemic Dissemination of Clostridium difficile Toxins A and B Is Associated With Severe, Fatal Disease in Animal Models.
Published in:
Journal of Infectious Diseases, 2012, v. 205, n. 3, p. 384, doi. 10.1093/infdis/jir748
By:
- Steele, Jennifer;
- Chen, Kevin;
- Sun, Xingmin;
- Zhang, Yongrong;
- Wang, Haiying;
- Tzipori, Saul;
- Feng, Hanping
Publication type:
Article
Piglet Models of Acute or Chronic Clostridium difficile Illness.
Published in:
Journal of Infectious Diseases, 2010, v. 201, n. 3, p. 428, doi. 10.1086/649799
By:
- Steele, Jennifer;
- Feng, Hanping;
- Parry, Nicola;
- Tzipori, Saul
Publication type:
Article
Newly identified bacteriolytic enzymes that target a wide range of clinical isolates of Clostridium difficile.
Published in:
Biotechnology & Bioengineering, 2016, v. 113, n. 12, p. 2568, doi. 10.1002/bit.26029
By:
- Mehta, Krunal K.;
- Paskaleva, Elena E.;
- Wu, Xia;
- Grover, Navdeep;
- Mundra, Ruchir V.;
- Chen, Kevin;
- Zhang, Yongrong;
- Yang, Zhiyong;
- Feng, Hanping;
- Dordick, Jonathan S.;
- Kane, Ravi S.
Publication type:
Article
Tumor-derived chaperone-rich cell lysates are effective therapeutic vaccines against a variety of cancers.
Published in:
Cancer Immunology, Immunotherapy, 2003, v. 52, n. 4, p. 226, doi. 10.1007/s00262-002-0359-2
By:
- Graner, Michael W.;
- Yi Zeng;
- Hanping Feng;
- Katsanis, Emmanuel
Publication type:
Article
Dendritic-cell-peptide immunization provides immunoprotection against bcr-abl -positive leukemia in mice.
Published in:
Cancer Immunology, Immunotherapy, 2001, v. 50, n. 1, p. 31, doi. 10.1007/PL00006680
By:
- Lin He;
- Hanping Feng;
- Raymond, Amy;
- Kreeger, Meghan;
- Yi Zeng;
- Graner, Michael;
- Whitesell, Luke;
- Katsanis, Emmanuel
Publication type:
Article
ADS024, a Bacillus velezensis strain, protects human colonic epithelial cells against C. difficile toxin-mediated apoptosis.
Published in:
Frontiers in Microbiology, 2023, v. 14, p. 1, doi. 10.3389/fmicb.2022.1072534
By:
- Ying Xie;
- Estrada, Andrea Chupina;
- Nelson, Becca;
- Hanping Feng;
- Charalabos Pothoulakis;
- Laurent Chesnel;
- Hon Wai Koon
Publication type:
Article
Host-targeted niclosamide inhibits C. difficile virulence and prevents disease in mice without disrupting the gut microbiota.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07705-w
By:
- Tam, John;
- Hamza, Therwa;
- Ma, Bing;
- Chen, Kevin;
- Beilhartz, Greg L.;
- Ravel, Jacques;
- Feng, Hanping;
- Melnyk, Roman A.
Publication type:
Article
Establishment of a gnotobiotic pig model of Clostridioides difficile infection and disease.
Published in:
Gut Pathogens, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13099-022-00496-y
By:
- Nyblade, Charlotte;
- Parreno, Viviana;
- Zhou, Peng;
- Hensley, Casey;
- Oakes, Vanessa;
- Mahsoub, Hassan M.;
- Kiley, Kelsey;
- Frazier, Maggie;
- Frazier, Annie;
- Zhang, Yongrong;
- Feng, Hanping;
- Yuan, Lijuan
Publication type:
Article
Down-regulation of interleukin-16 in human mast cells HMC-1 by Clostridium difficile toxins A and B.
Published in:
Naunyn-Schmiedeberg's Archives of Pharmacology, 2011, v. 383, n. 3, p. 285, doi. 10.1007/s00210-010-0592-8
By:
- Gerhard, Ralf;
- Queißer, Swenja;
- Tatge, Helma;
- Meyer, Gesa;
- Dittrich-Breiholz, Oliver;
- Kracht, Michael;
- Feng, Hanping;
- Just, Ingo
Publication type:
Article
A fine-tuned yeast surface-display/secretion platform enables the rapid discovery of neutralizing antibodies against Clostridioides difficile toxins.
Published in:
Microbial Cell Factories, 2023, v. 22, n. 1, p. 1, doi. 10.1186/s12934-023-02200-4
By:
- Sun, Ying;
- Zhang, Yongrong;
- Yu, Hua;
- Saint Fleur, Ashley;
- Yu, Di;
- Yang, Zhiyong;
- Feng, Hanping
Publication type:
Article
Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B.
Published in:
Cell Research, 2015, v. 25, n. 2, p. 157, doi. 10.1038/cr.2014.169
By:
- Yuan, Pengfei;
- Zhang, Hongmin;
- Cai, Changzu;
- Zhu, Shiyou;
- Zhou, Yuexin;
- Yang, Xiaozhou;
- He, Ruina;
- Li, Chan;
- Guo, Shengjie;
- Li, Shan;
- Huang, Tuxiong;
- Perez-Cordon, Gregorio;
- Feng, Hanping;
- Wei, Wensheng
Publication type:
Article
Imatinib mesylate effectively combines with chaperone-rich cell lysate-loaded dendritic cells to treat bcr-abl.
Published in:
International Journal of Cancer, 2004, v. 110, n. 2, p. 251, doi. 10.1002/ijc.20115
By:
- Zeng, Yi;
- Graner, Michael W.;
- Feng, Hanping;
- Li, Gang;
- Katsanis, Emmanuel
Publication type:
Article
An Analysis of Spatial Construction in Pictorial Art from the Perspective of Formalism.
Published in:
Harmonia: Journal of Arts Research & Education, 2024, v. 24, n. 1, p. 149, doi. 10.15294/harmonia.v24i1.42152
By:
- Feng Hanping;
- Safrizal Shahir
Publication type:
Article
Identification of an Essential Region for Translocation of Clostridium difficile Toxin B.
Published in:
Toxins, 2016, v. 8, n. 8, p. 241, doi. 10.3390/toxins8080241
By:
- Shuyi Chen;
- Haiying Wang;
- Huawei Gu;
- Chunli Sun;
- Shan Li;
- Hanping Feng;
- Jufang Wang
Publication type:
Article
A probiotic yeast-based immunotherapy against Clostridioides difficile infection.
Published in:
Science Translational Medicine, 2020, v. 12, n. 567, p. 1, doi. 10.1126/scitranslmed.aax4905
By:
- Chen, Kevin;
- Zhu, Yixuan;
- Zhang, Yongrong;
- Hamza, Therwa;
- Yu, Hua;
- Saint Fleur, Ashley;
- Galen, James;
- Yang, Zhiyong;
- Feng, Hanping
Publication type:
Article
The Complete Genome of Brucella Suis 019 Provides Insights on Cross-Species Infection.
Published in:
Genes, 2016, v. 7, n. 2, p. 7, doi. 10.3390/genes7020007
By:
- Yuanzhi Wang;
- Zhen Wang;
- Xin Chen;
- Hui Zhang;
- Fei Guo;
- Ke Zhang;
- Hanping Feng;
- Wenyi Gu;
- Changxin Wu;
- Lei Ma;
- Tiansen Li;
- Chuangfu Chen;
- Shan Gao
Publication type:
Article
Loratadine as an Anti-inflammatory Agent Against Clostridium difficile Toxin B.
Published in:
Journal of Infectious Diseases, 2024, v. 230, n. 3, p. 545, doi. 10.1093/infdis/jiae021
By:
- Xie, Ying;
- Irwin, Sophie;
- Estrada, Andrea Chupina;
- Nelson, Becca;
- Bullock, Ashlen;
- Fontenot, Lindsey;
- Feng, Hanping;
- Sun, Mingjun;
- Koon, Hon Wai
Publication type:
Article
Genistein Inhibits Clostridioides difficile Infection via Estrogen Receptors and Lysine-Deficient Protein Kinase 1.
Published in:
Journal of Infectious Diseases, 2023, v. 227, n. 6, p. 806, doi. 10.1093/infdis/jiad008
By:
- Xie, Ying;
- Fontenot, Lindsey;
- Estrada, Andrea Chupina;
- Nelson, Becca;
- Bullock, Ashlen;
- Faull, Kym F;
- Feng, Hanping;
- Sun, Mingjun;
- Koon, Hon Wai
Publication type:
Article
Therapeutic Mechanism of Macrophage Inflammatory Protein 1 α Neutralizing Antibody (CCL3) in Clostridium difficile Infection in Mice.
Published in:
2020
By:
- Wang, Jiani;
- Ortiz, Christina;
- Fontenot, Lindsey;
- Mukhopadhyay, Riya;
- Xie, Ying;
- Chen, Xinhua;
- Feng, Hanping;
- Pothoulakis, Charalabos;
- Koon, Hon Wai
Publication type:
journal article

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