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Scalable, cGMP-compatible purification of extracellular vesicles carrying bioactive human heterodimeric IL-15/lactadherin complexes.
Published in:
Journal of Extracellular Vesicles, 2018, v. 7, n. 1, p. 1, doi. 10.1080/20013078.2018.1442088
By:
- Watson, Dionysios C.;
- Yung, Bryant C.;
- Bergamaschi, Cristina;
- Chowdhury, Bhabadeb;
- Bear, Jenifer;
- Stellas, Dimitris;
- Morales-Kastresana, Aizea;
- Jones, Jennifer C.;
- Felber, Barbara K.;
- Chen, Xiaoyuan;
- Pavlakis, George N.
Publication type:
Article
Scalable, cGMP-compatible purification of extracellular vesicles carrying bioactive human heterodimeric IL-15/lactadherin complexes.
Published in:
Journal of Extracellular Vesicles, 2018, v. 7, n. 1, p. 1, doi. 10.1080/20013078.2018.1442088
By:
- Watson, Dionysios C.;
- Yung, Bryant C.;
- Bergamaschi, Cristina;
- Chowdhury, Bhabadeb;
- Bear, Jenifer;
- Stellas, Dimitris;
- Morales-Kastresana, Aizea;
- Jones, Jennifer C.;
- Felber, Barbara K.;
- Chen, Xiaoyuan;
- Pavlakis, George N.
Publication type:
Article
Comparative immunogenicity of an mRNA/LNP and a DNA vaccine targeting HIV gag conserved elements in macaques.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.945706
By:
- Valentin, Antonio;
- Bergamaschi, Cristina;
- Rosati, Margherita;
- Angel, Matthew;
- Burns, Robert;
- Agarwal, Mahesh;
- Gergen, Janina;
- Petsch, Benjamin;
- Oostvogels, Lidia;
- Loeliger, Edde;
- Chew, Kara W.;
- Deeks, Steven G.;
- Mullins, James I.;
- Pavlakis, George N.;
- Felber, Barbara K.
Publication type:
Article
Reduced Antibodies and Innate Cytokine Changes in SARS-CoV-2 BNT162b2 mRNA Vaccinated Transplant Patients With Hematological Malignancies.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.899972
By:
- Bergamaschi, Cristina;
- Pagoni, Maria;
- Rosati, Margherita;
- Angel, Matthew;
- Tzannou, Ifigeneia;
- Vlachou, Margarita;
- Darmani, Ismini;
- Ullah, Amirah;
- Bear, Jenifer;
- Devasundaram, Santhi;
- Burns, Robert;
- Baltadakis, Ioannis;
- Gigantes, Stavros;
- Dimopoulos, Meletios-Athanasios;
- Pavlakis, George N.;
- Terpos, Evangelos;
- Felber, Barbara K.
Publication type:
Article
Sequential Analysis of Binding and Neutralizing Antibody in COVID-19 Convalescent Patients at 14 Months After SARS-CoV-2 Infection.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.793953
By:
- Rosati, Margherita;
- Terpos, Evangelos;
- Ntanasis-Stathopoulos, Ioannis;
- Agarwal, Mahesh;
- Bear, Jenifer;
- Burns, Robert;
- Hu, Xintao;
- Korompoki, Eleni;
- Donohue, Duncan;
- Venzon, David J.;
- Dimopoulos, Meletios-Athanasios;
- Pavlakis, George N.;
- Felber, Barbara K.
Publication type:
Article
Gammaretrovirus mRNA expression is mediated by a novel, bipartite post-transcriptional regulatory element.
Published in:
Nucleic Acids Research, 2014, v. 42, n. 17, p. 11092, doi. 10.1093/nar/gku798
By:
- Pilkington, Guy R.;
- Purzycka, Katarzyna J.;
- Bear, Jenifer;
- Le Grice, Stuart F. J.;
- Felber, Barbara K.
Publication type:
Article
Nuclear export factor RBM15 facilitates the access of DBP5 to mRNA.
Published in:
Nucleic Acids Research, 2009, v. 37, n. 21, p. 7151, doi. 10.1093/nar/gkp782
By:
- Zolotukhin, Andrei S.;
- Uranishi, Hiroaki;
- Lindtner, Susan;
- Bear, Jenifer;
- Pavlakis, George N.;
- Felber, Barbara K.
Publication type:
Article
Mosaic vaccines elicit CD8<sup>+</sup> T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys.
Published in:
Nature Medicine, 2010, v. 16, n. 3, p. 324, doi. 10.1038/nm.2108
By:
- Santra, Sampa;
- Hua-Xin Liao;
- Ruijin Zhang;
- Muldoon, Mark;
- Watson, Sydeaka;
- Fischer, Will;
- Theiler, James;
- Szinger, James;
- Balachandran, Harikrishnan;
- Buzby, Adam;
- Quinn, David;
- Parks, Robert J.;
- Chun-Yen Tsao;
- Carville, Angela;
- Mansfield, Keith G.;
- Pavlakis, George N.;
- Felber, Barbara K.;
- Haynes, Barton F.;
- Korber, Bette T.;
- Letvin, Norman L.
Publication type:
Article
Efficient Systemic Expression of Bioactive IL-15 in Mice upon Delivery of Optimized DNA Expression Plasmids.
Published in:
DNA & Cell Biology, 2007, v. 26, n. 12, p. 827, doi. 10.1089/dna.2007.0645
By:
- Jalah, Rashmi;
- Rosati, Margherita;
- Kulkarni, Viraj;
- Patel, Vainav;
- Bergamaschi, Cristina;
- Valentin, Antonio;
- Zhang, Gen-Mu;
- Sidhu, Maninder K.;
- Eldridge, John H.;
- Weiner, David B.;
- Pavlakis, George N.;
- Felber, Barbara K.
Publication type:
Article
Immunogenicity Testing of a Novel Engineered HIV-1 Envelope Gp140 DNA Vaccine Construct.
Published in:
DNA & Cell Biology, 2006, v. 25, n. 7, p. 383, doi. 10.1089/dna.2006.25.383
By:
- Kumar, Sanjeev;
- Jian Yan;
- Muthumani, Karuppiah;
- Ramanathan, Mathura P.;
- Yoon, Hanna;
- Pavlakis, George N.;
- Felber, Barbara K.;
- Sidhu, Maninder;
- Boyer, Jean D.;
- Weiner, David B.
Publication type:
Article
XBB.1.5 neutralizing antibodies upon bivalent COVID‐19 vaccination are similar to XBB but lower than BQ.1.1.
Published in:
American Journal of Hematology, 2023, v. 98, n. 5, p. E123, doi. 10.1002/ajh.26887
By:
- Devasundaram, Santhi;
- Terpos, Evangelos;
- Rosati, Margherita;
- Ntanasis‐Stathopoulos, Ioannis;
- Bear, Jenifer;
- Burns, Robert;
- Skourti, Stamatia;
- Malandrakis, Panagiotis;
- Trougakos, Ioannis P.;
- Dimopoulos, Meletios‐Athanasios;
- Pavlakis, George N.;
- Felber, Barbara K.
Publication type:
Article
Distinct neutralization profile of spike variants by antibodies induced upon SARS‐CoV‐2 infection or vaccination.
Published in:
American Journal of Hematology, 2022, v. 97, n. 1, p. E3, doi. 10.1002/ajh.26380
By:
- Rosati, Margherita;
- Terpos, Evangelos;
- Agarwal, Mahesh;
- Karalis, Vangelis;
- Bear, Jenifer;
- Burns, Robert;
- Hu, Xintao;
- Papademetriou, Demetrios;
- Ntanasis‐Stathopoulos, Ioannis;
- Trougakos, Ioannis P.;
- Dimopoulos, Meletios‐Athanasios;
- Pavlakis, George N.;
- Felber, Barbara K.
Publication type:
Article
HIV-1 Conserved Elements p24CE DNA Vaccine Induces Humoral Immune Responses with Broad Epitope Recognition in Macaques.
Published in:
PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0111085
By:
- Kulkarni, Viraj;
- Valentin, Antonio;
- Rosati, Margherita;
- Rolland, Morgane;
- Mullins, James I.;
- Pavlakis, George N.;
- Felber, Barbara K.
Publication type:
Article
Altered Response Hierarchy and Increased T-Cell Breadth upon HIV-1 Conserved Element DNA Vaccination in Macaques.
Published in:
PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0086254
By:
- Kulkarni, Viraj;
- Valentin, Antonio;
- Rosati, Margherita;
- Alicea, Candido;
- Singh, Ashish K.;
- Jalah, Rashmi;
- Broderick, Kate E.;
- Sardesai, Niranjan Y.;
- Le Gall, Sylvie;
- Mothe, Beatriz;
- Brander, Christian;
- Rolland, Morgane;
- Mullins, James I.;
- Pavlakis, George N.;
- Felber, Barbara K.
Publication type:
Article
Live Attenuated Rev-Independent Nef¯SIV Enhances Acquisition of Heterologous SIVsmE660 in Acutely Vaccinated Rhesus Macaques.
Published in:
PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0075556
By:
- Byrareddy, Siddappa N.;
- Ayash-Rashkovsky, Mila;
- Kramer, Victor G.;
- Lee, Sandra J.;
- Correll, Mick;
- Novembre, Francis J.;
- Villinger, Francois;
- Johnson, Welkin E.;
- von Gegerfelt, Agneta;
- Felber, Barbara K.;
- Ruprecht, Ruth M.
Publication type:
Article
HIV-1 p24<sup>gag</sup> Derived Conserved Element DNA Vaccine Increases the Breadth of Immune Response in Mice.
Published in:
PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0060245
By:
- Kulkarni, Viraj;
- Rosati, Margherita;
- Valentin, Antonio;
- Ganneru, Brunda;
- Singh, Ashish K.;
- Yan, Jian;
- Rolland, Morgane;
- Alicea, Candido;
- Beach, Rachel Kelly;
- Zhang, Gen-Mu;
- Le Gall, Sylvie;
- Broderick, Kate E.;
- Sardesai, Niranjan Y.;
- Heckerman, David;
- Mothe, Beatriz;
- Brander, Christian;
- Weiner, David B.;
- Mullins, James I.;
- Pavlakis, George N.;
- Felber, Barbara K.
Publication type:
Article
CTL Responses of High Functional Avidity and Broad Variant Cross-Reactivity Are Associated with HIV Control.
Published in:
PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0029717
By:
- Mothe, Beatriz;
- Llano, Anuska;
- Ibarrondo, Javier;
- Zamarreño, Jennifer;
- Schiaulini, Mattia;
- Miranda, Cristina;
- Ruiz-Riol, Marta;
- Berger, Christoph T.;
- M. José Herrero;
- Palou, Eduard;
- Plana, Montse;
- Rolland, Morgane;
- Khatri, Ashok;
- Heckerman, David;
- Pereyra, Florencia;
- Walker, Bruce D.;
- Weiner, David;
- Paredes, Roger;
- Clotet, Bonaventura;
- Felber, Barbara K.
Publication type:
Article
Control of SARS-CoV-2 infection after Spike DNA or Spike DNA+Protein co-immunization in rhesus macaques.
Published in:
PLoS Pathogens, 2021, v. 17, n. 9, p. 1, doi. 10.1371/journal.ppat.1009701
By:
- Rosati, Margherita;
- Agarwal, Mahesh;
- Hu, Xintao;
- Devasundaram, Santhi;
- Stellas, Dimitris;
- Chowdhury, Bhabadeb;
- Bear, Jenifer;
- Burns, Robert;
- Donohue, Duncan;
- Pessaint, Laurent;
- Andersen, Hanne;
- Lewis, Mark G.;
- Terpos, Evangelos;
- Dimopoulos, Meletios Athanasios;
- Wlodawer, Alexander;
- Mullins, James I.;
- Venzon, David J.;
- Pavlakis, George N.;
- Felber, Barbara K.
Publication type:
Article
Competition for cellular factors that activate metallothionein gene transcription.
Published in:
Nature, 1984, v. 312, n. 5996, p. 781, doi. 10.1038/312781a0
By:
- Séguin, Carl;
- Felber, Barbara K.;
- Carter, Anthony D.;
- Hamer, Dean H.
Publication type:
Article
Low Spike Antibody Levels and Impaired BA.4/5 Neutralization in Patients with Multiple Myeloma or Waldenstrom's Macroglobulinemia after BNT162b2 Booster Vaccination.
Published in:
Cancers, 2022, v. 14, n. 23, p. 5816, doi. 10.3390/cancers14235816
By:
- Rosati, Margherita;
- Terpos, Evangelos;
- Bear, Jenifer;
- Burns, Robert;
- Devasundaram, Santhi;
- Ntanasis-Stathopoulos, Ioannis;
- Gavriatopoulou, Maria;
- Kastritis, Efstathios;
- Dimopoulos, Meletios-Athanasios;
- Pavlakis, George N.;
- Felber, Barbara K.
Publication type:
Article
Heterodimeric IL-15 in Cancer Immunotherapy.
Published in:
Cancers, 2021, v. 13, n. 4, p. 837, doi. 10.3390/cancers13040837
By:
- Bergamaschi, Cristina;
- Stravokefalou, Vasiliki;
- Stellas, Dimitris;
- Karaliota, Sevasti;
- Felber, Barbara K.;
- Pavlakis, George N.;
- Platanias, Leonidas C.
Publication type:
Article
Correction: Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes.
Published in:
2018
By:
- Watson, Dionysios C.;
- Moysi, Eirini;
- Valentin, Antonio;
- Bergamaschi, Cristina;
- Devasundaram, Santhi;
- Fortis, Sotirios P.;
- Bear, Jenifer;
- Chertova, Elena;
- Bess, Julian;
- Sowder, Ray;
- Venzon, David J.;
- Deleage, Claire;
- Estes, Jacob D.;
- Lifson, Jeffrey D.;
- Petrovas, Constantinos;
- Felber, Barbara K.;
- Pavlakis, George N.
Publication type:
Correction Notice
Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes.
Published in:
PLoS Pathogens, 2018, v. 14, n. 2, p. 1, doi. 10.1371/journal.ppat.1006902
By:
- Watson, Dionysios C.;
- Moysi, Eirini;
- Valentin, Antonio;
- Bergamaschi, Cristina;
- Devasundaram, Santhi;
- Fortis, Sotirios P.;
- Bear, Jenifer;
- Chertova, Elena;
- Jr.Bess, Julian;
- Sowder, Ray;
- Venzon, David J.;
- Deleage, Claire;
- Estes, Jacob D.;
- Lifson, Jeffrey D.;
- Petrovas, Constantinos;
- Felber, Barbara K.;
- Pavlakis, George N.
Publication type:
Article
Anti–SARS-CoV-2 Antibody Responses in Convalescent Plasma Donors Are Increased in Hospitalized Patients; Subanalyses of a Phase 2 Clinical Study.
Published in:
Microorganisms, 2020, v. 8, n. 12, p. 1885, doi. 10.3390/microorganisms8121885
By:
- Terpos, Evangelos;
- Politou, Marianna;
- Sergentanis, Theodoros N.;
- Mentis, Andreas;
- Rosati, Margherita;
- Stellas, Dimitris;
- Bear, Jenifer;
- Hu, Xintao;
- Felber, Barbara K.;
- Pappa, Vassiliki;
- Pagoni, Maria;
- Grouzi, Elisavet;
- Labropoulou, Stavroula;
- Charitaki, Ioanna;
- Ntanasis-Stathopoulos, Ioannis;
- Moschandreou, Dimitra;
- Bouhla, Anthi;
- Saridakis, Stylianos;
- Korompoki, Eleni;
- Giatra, Chara
Publication type:
Article
Efficient ex vivo expansion of conserved element vaccinespecific CD8+ T-cells from SHIV-infected, ART-suppressed nonhuman primates .
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1188018
By:
- Dross, Sandra;
- Venkataraman, Rasika;
- Patel, Shabnum;
- Huang, Meei-Li;
- Bollard, Catherine M.;
- Rosati, Margherita;
- Pavlakis, George N.;
- Felber, Barbara K.;
- Bar, Katharine J.;
- Shaw, George M.;
- Jerome, Keith R.;
- Mullins, James I.;
- Kiem, Hans-Peter;
- Fuller, Deborah Heydenburg;
- Peterson, Christopher W.
Publication type:
Article
Identification and characterization of the mouse nuclear export factor (Nxf) family members.
Published in:
Nucleic Acids Research, 2005, v. 33, n. 12, p. 3855, doi. 10.1093/nar/gki706
By:
- Tan, Wei;
- Zolotukhin, Andrei S.;
- Tretyakova, Irina;
- Bear, Jenifer;
- Lindtner, Susan;
- Smulevitch, Sergey V.;
- Felber, Barbara K.
Publication type:
Article
Immunotherapy with DNA vaccine and live attenuated rubella/SIV gag vectors plus early ART can prevent SIVmac251 viral rebound in acutely infected rhesus macaques.
Published in:
PLoS ONE, 2020, v. 15, n. 3, p. 1, doi. 10.1371/journal.pone.0228163
By:
- Virnik, Konstantin;
- Rosati, Margherita;
- Medvedev, Alexei;
- Scanlan, Aaron;
- Walsh, Gabrielle;
- Dayton, Frances;
- Broderick, Kate E.;
- Lewis, Mark;
- Bryson, Yvonne;
- Lifson, Jeffrey D.;
- Ruprecht, Ruth M.;
- Felber, Barbara K.;
- Berkower, Ira
Publication type:
Article
DNA vaccination by intradermal electroporation induces long-lasting immune responses in rhesus macaques.
Published in:
Journal of Medical Primatology, 2014, v. 43, n. 5, p. 329, doi. 10.1111/jmp.12123
By:
- Kulkarni, Viraj;
- Rosati, Margherita;
- Jalah, Rashmi;
- Ganneru, Brunda;
- Alicea, Candido;
- Yu, Lei;
- Guan, Yongjun;
- LaBranche, Celia;
- Montefiori, David C.;
- King, Alan D.;
- Valentin, Antonio;
- Pavlakis, George N.;
- Felber, Barbara K.
Publication type:
Article
Improved expression and delivery of IL-15 DNA vectors in combination with IL-15 receptor alpha in mice and macaques provide a potent growth signal for NK and T cells.
Published in:
FASEB Journal, 2008, v. 22, p. 429, doi. 10.1096/fasebj.22.2_supplement.429
By:
- Bergamaschi, Cristina;
- Valentin, Antonio;
- Jalah, Rashmi;
- Rosati, Margherita;
- Kulkarni, Viraj;
- Alicea, Candido;
- Patel, Vainav;
- Zhang, Gen-Mu;
- Kjeken, Rune;
- Felber, Barbara K.;
- Pavlakis, George N.
Publication type:
Article
A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques.
Published in:
2015
By:
- Mothe, Beatriz;
- Hu, Xintao;
- Llano, Anuska;
- Rosati, Margherita;
- Olvera, Alex;
- Kulkarni, Viraj;
- Valentin, Antonio;
- Alicea, Candido;
- Pilkington, Guy R;
- Sardesai, Niranjan Y;
- Rocafort, Muntsa;
- Crespo, Manel;
- Carrillo, Jorge;
- Marco, Andrés;
- Mullins, James I;
- Dorrell, Lucy;
- Hanke, Tomás;
- Clotet, Bonaventura;
- Pavlakis, George N;
- Felber, Barbara K
Publication type:
journal article
REBOUND DYNAMICS FOLLOWING IMMUNOTHERAPY WITH AN HIV VACCINE, TLR9 AGONIST, AND bNAbs.
Published in:
Topics in Antiviral Medicine, 2023, v. 31, n. 2, p. 172
By:
- Peluso, Michael J.;
- Deitchman, Amelia;
- Magombedze, Gesham;
- Williams, Meghann;
- Kumar, Nitasha;
- Mullins, James;
- Felber, Barbara K.;
- Pavlakis, George;
- Johnston, Rowena;
- Reeves, Jackie;
- Gama, Lucio;
- Nussenzweig, Michel C.;
- Henrich, Timothy;
- Rutishauser, Rachel L.;
- Deeks, Steven G.
Publication type:
Article
Live attenuated rubella vectors expressing SIV and HIV vaccine antigens replicate and elicit durable immune responses in rhesus macaques.
Published in:
Retrovirology, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-4690-10-99
By:
- Virnik, Konstantin;
- Hockenbury, Max;
- Yisheng Ni;
- Beren, Joel;
- Pavlakis, George N.;
- Felber, Barbara K.;
- Berkower, Ira
Publication type:
Article
RTE and CTE mRNA export elements synergistically increase expression of unstable, Rev-dependent HIV and SIV mRNAs.
Published in:
Retrovirology, 2006, v. 3, p. 6, doi. 10.1186/1742-4690-3-6
By:
- Smulevitch, Sergey;
- Bear, Jenifer;
- Alicea, Candido;
- Rosati, Margherita;
- Jalah, Rashmi;
- Zolotukhin, Andrei S.;
- Von Gegerfelt, Agneta;
- Michalowski, Daniel;
- Moroni, Christoph;
- Pavlakis, George N.;
- Felber, Barbara K.
Publication type:
Article

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