Works matching AU Farrell, Colm

Results: 21

Pediatric Population Pharmacokinetic Modeling and Exposure–Response Analysis of Ambrisentan in Pulmonary Arterial Hypertension and Comparison With Adult Data.

Published in:

Journal of Clinical Pharmacology, 2023, v. 63, n. 5, p. 593, doi. 10.1002/jcph.2199

By:

Okour, Malek;
Thapar, Mita M.;
Farrell, Colm;
Lukas, Mary Ann;
Beghetti, Maurice;
Beerahee, Misba

Publication type:

Article

Population pharmacokinetics of atacicept in systemic lupus erythematosus: An analysis of three clinical trials.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 8, p. 1157, doi. 10.1002/psp4.12982

By:

Pitsiu, Maria;
Yalkinoglu, Özkan;
Farrell, Colm;
Girard, Pascal;
Vazquez‐Mateo, Cristina;
Papasouliotis, Orestis

Publication type:

Article

Population pharmacokinetic modeling and simulation of maribavir to support dose selection and regulatory approval in adolescents with posttransplant refractory cytomegalovirus.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 5, p. 719, doi. 10.1002/psp4.12943

By:

Sun, Kefeng;
Hayes, Siobhan;
Farrell, Colm;
Song, Ivy H.

Publication type:

Article

A Physiologically Based Pharmacokinetic Model to Predict Potential Drug–Drug Interactions and Inform Dosing of Acumapimod, an Oral p38 MAPK Inhibitor.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 1, p. 30, doi. 10.1002/psp4.12565

By:

Agyemang, Alex;
Farrell, Colm;
Moore, William;
Parkin, Jacqueline

Publication type:

Article

Pharmacokinetic profile of ganciclovir after its oral administration and from its prodrug, valganciclovir, in solid organ transplant recipients.

Published in:

2005

By:

Wiltshire, Hugh;
Hirankarn, Sarapee;
Farrell, Colm;
Paya, Carlos;
Pescovitz, Mark D.;
Humar, Atul;
Dominguez, Edward;
Washburn, Kenneth;
Blumberg, Emily;
Alexander, Barbara;
Freeman, Richard;
Heaton, Nigel;
Valganciclovir Solid Organ Transplant Study Group

Publication type:

journal article

Development of Xanamem, an isoform 1 specific inhibitor of 11‐βHSD, as a procognitive and disease modifying treatment for mild/moderate Alzheimer's disease. A pharmacodynamic and biomarker driven approach.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S6, p. 1, doi. 10.1002/alz.089127

By:

Rolan, Paul;
Taylor, Jack;
Seckl, Jonathan;
Harrison, John E;
Chen, Christopher Li‐Hsian;
Farrell, Colm;
Maruff, Paul;
Woodward, Michael;
Hilt, Dana

Publication type:

Article

Population pharmacokinetics and exposure–response relationships of maribavir in transplant recipients with cytomegalovirus infection.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2024, v. 51, n. 6, p. 887, doi. 10.1007/s10928-024-09939-2

By:

Song, Ivy H.;
Chen, Grace;
Hayes, Siobhan;
Farrell, Colm;
Jomphe, Claudia;
Gosselin, Nathalie H.;
Sun, Kefeng

Publication type:

Article

Population pharmacokinetics of farletuzumab, a humanized monoclonal antibody against folate receptor alpha, in epithelial ovarian cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 70, n. 5, p. 727, doi. 10.1007/s00280-012-1959-y

By:

Farrell, Colm;
Schweizer, Charles;
Wustner, Jason;
Weil, Susan;
Namiki, Masayuki;
Nakano, Tomohisa;
Nakai, Kenya;
Phillips, Martin

Publication type:

Article

Oliceridine, a Novel G Protein-Biased Ligand at the μ-Opioid Receptor,Demonstrates a Predictable Relationship Between Plasma Concentrations and Pain Relief. II: Simulation of Potential Phase 3 Study Designs Using a Pharmacokinetic/Pharmacodynamic Model Michael

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 6, p. 762, doi. 10.1002/jcph.1075

By:

Fossler, Michael J.;
Sadler, Brian M.;
Farrell, Colm;
Burt, David A.;
Pitsiu, Maria;
Skobieranda, Franck;
Soergel, David G.

Publication type:

Article

Oliceridine (TRV130), a Novel G Protein-Biased Ligand at the μ-Opioid Receptor,Demonstrates a Predictable Relationship Between Plasma Concentrations and Pain Relief. I: Development of a Pharmacokinetic/Pharmacodynamic Model.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 6, p. 750, doi. 10.1002/jcph.1076

By:

Fossler, Michael J.;
Sadler, Brian M.;
Farrell, Colm;
Burt, David A.;
Pitsiu, Maria;
Skobieranda, Franck;
Soergel, David G.

Publication type:

Article

Population Pharmacokinetics of Telbivudine and Determination of Dose Adjustment for Patients With Renal Impairment.

Published in:

Journal of Clinical Pharmacology, 2010, v. 50, n. 6, p. 725, doi. 10.1177/0091270009333555

By:

Xiao-Jian Zhou;
Ke, June;
Sallas, William M.;
Farrell, Colm;
Mayers, Douglas L.;
Pentikis, Helen S.

Publication type:

Article

Population Pharmacokinetics of Telbivudine and Determination of Dose Adjustment for Patients With Renal Impairment.

Published in:

Journal of Clinical Pharmacology, 2009, v. 49, n. 6, p. 725, doi. 10.1177/0091270009333555

By:

Xiao-Jian Zhou;
Ke, June;
Sallas, William M.;
Farrell, Colm;
Mayers, Douglas L.;
Pentikis, Helen S.

Publication type:

Article

Population pharmacokinetic and pharmacodynamic analyses of safinamide in subjects with Parkinson's disease.

Published in:

Pharmacology Research & Perspectives, 2016, v. 4, n. 5, p. n/a, doi. 10.1002/prp2.251

By:

Loprete, Luca;
Leuratti, Chiara;
Cattaneo, Carlo;
Thapar, Mita M.;
Farrell, Colm;
Sardina, Marco

Publication type:

Article

A population pharmacokinetic meta-analysis of custirsen, an antisense oligonucleotide, in oncology patients and healthy subjects.

Published in:

British Journal of Clinical Pharmacology, 2017, v. 83, n. 9, p. 1932, doi. 10.1111/bcp.13287

By:

Edwards, Alena Y.;
Elgart, Anna;
Farrell, Colm;
Barnett-Griness, Ofra;
Rabinovich-Guilatt, Laura;
Spiegelstein, Ofer

Publication type:

Article

Population pharmacokinetic/pharmacodynamic modelling of eltrombopag in healthy volunteers and subjects with chronic liver disease.

Published in:

British Journal of Clinical Pharmacology, 2014, v. 77, n. 3, p. 532, doi. 10.1111/bcp.12244

By:

Farrell, Colm;
Hayes, Siobhan C.;
Wire, Mary;
Zhang, Jianping

Publication type:

Article

Population pharmacokinetics of recombinant human C1 inhibitor in patients with hereditary angioedema.

Published in:

British Journal of Clinical Pharmacology, 2013, v. 76, n. 6, p. 897, doi. 10.1111/bcp.12132

By:

Farrell, Colm;
Hayes, Siobhan;
Relan, Anurag;
Amersfoort, Edwin S.;
Pijpstra, Rienk;
Hack, C. Erik

Publication type:

Article

Challenges and Opportunities in Establishing Scientific and Regulatory Standards for Assuring Therapeutic Equivalence of Modified Release Products: Workshop Summary Report.

Published in:

2010

By:

Chen, Mei-Ling;
Shah, Vinod;
Ganes, Derek;
Midha, Kamal;
Caro, James;
Nambiar, Prabu;
Rocci, Mario;
Thombre, Avinash;
Abrahamsson, Bertil;
Conner, Dale;
Davit, Barbara;
Fackler, Paul;
Farrell, Colm;
Gupta, Suneel;
Katz, Russell;
Mehta, Mehul;
Preskorn, Sheldon;
Sanderink, Gerard;
Stavchansky, Salomon;
Temple, Robert

Publication type:

Report

Modeling and Simulation Support Eltrombopag Dosing in Thrombocytopenic Patients with Chronic HCV Infection.

Published in:

Pharmaceutical Research, 2015, v. 32, n. 6, p. 2015, doi. 10.1007/s11095-014-1594-x

By:

Zhang, Jianping;
Thapar, Mita;
Farrell, Colm;
Wire, Mary

Publication type:

Article

Belantamab mafodotin concentration–QTc relationships in patients with relapsed or refractory multiple myeloma from the DREAMM‐1 and ‐2 studies.

Published in:

British Journal of Clinical Pharmacology, 2024, v. 90, n. 10, p. 2571, doi. 10.1111/bcp.16133

By:

Jewell, Roxanne C.;
Mills, Richard J.;
Farrell, Colm;
Visser, Sandra A. G.

Publication type:

Article

Model‐informed Evidence for Clinical Non‐inferiority of Every‐2‐Weeks Versus Standard Weekly Dosing Schedule of Cetuximab in Metastatic Colorectal Cancer.

Published in:

Clinical Pharmacology & Therapeutics, 2024, v. 116, n. 4, p. 1071, doi. 10.1002/cpt.3345

By:

Milenković‐Grišić, Ana‐Marija;
Hayes, Siobhán;
Farrell, Colm;
Kuroki, Yoshihiro;
Bertolino, Mauro;
Venkatakrishnan, Karthik;
Girard, Pascal

Publication type:

Article

Population Pharmacokinetic Analysis of Fluticasone Furoate/Umeclidinium Bromide/Vilanterol in Patients with Chronic Obstructive Pulmonary Disease.

Published in:

2020

By:

Mehta, Rashmi;
Farrell, Colm;
Hayes, Siobhán;
Birk, Ruby;
Okour, Malek;
Lipson, David A.

Publication type:

journal article