Works by Fantus, I. George

Results: 34

Circulating Tumor Necrosis Factor-a Concentrations in a Native Canadian Population with High Rates of Type 2 Diabetes Mellitus.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1999, v. 84, n. 1, p. 272, doi. 10.1210/jcem.84.1.5405

By:

ZINMAN, BERNARD;
HANLEY, ANTHONY J. G.;
HARRIS, STEWART B.;
KWAN, JEREMY;
FANTUS, I. GEORGE

Publication type:

Article

Metformin in women with type 2 diabetes in pregnancy (MiTy): a multi-center randomized controlled trial.

Published in:

2016

By:

Feig, Denice S.;
Murphy, Kellie;
Asztalos, Elizabeth;
Tomlinson, George;
Sanchez, Johanna;
Zinman, Bernard;
Ohlsson, Arne;
Ryan, Edmond A.;
Fantus, I. George;
Armson, Anthony B.;
Lipscombe, Lorraine L.;
Barrett, Jon F. R.;
MiTy Collaborative Group

Publication type:

journal article

Curcumin Prevents High Fat Diet Induced Insulin Resistance and Obesity via Attenuating Lipogenesis in Liver and Inflammatory Pathway in Adipocytes.

Published in:

PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0028784

By:

Weijuan Shao;
Zhiwen Yu;
Yuting Chiang;
Yi Yang;
Tuanyao Chai;
Foltz, Warren;
Huogen Lu;
Fantus, I. George;
Jin, Tianru

Publication type:

Article

Gene and protein kinase expression profiling of reactive oxygen species-associated lipotoxicity in the pancreatic beta-cell line MIN6.

Published in:

2004

By:

Wang, Xiaolin;
Li, Hui;
De Leo, Domenica;
Guo, Wanbei;
Koshkin, Vasilij;
Fantus, I George;
Giacca, Adria;
Chan, Catherine B;
Der, Sandy;
Wheeler, Michael B

Publication type:

journal article

Gene and Protein Kinase Expression Profiling of Reactive Oxygen Species -- Associated Lipotoxicity in the Pancreatic β-Cell Line MIN6.

Published in:

Diabetes, 2004, v. 53, n. 1, p. 129, doi. 10.2337/diabetes.53.1.129

By:

Xiaolin Wang;
De Leo, Domenica;
Koshkin, Vasilij;
Giacca, Adria;
Hui Li;
Wheeler, Michael B.;
Fantus, I. George;
Guo, Wanbei;
Der, Sandy;
Chan, Catherine B.

Publication type:

Article

Decreased in situ insulin receptor dephosphorylation in hyperglycemia-induced insulin resistance in rat adipocytes.

Published in:

2001

By:

Tang, Shangguo;
Le-Tien, Hoang;
Goldstein, Barry J.;
Shin, Phillip;
Lai, Robert;
Fantus, I. George;
Tang, S;
Le-Tien, H;
Goldstein, B J;
Shin, P;
Lai, R;
Fantus, I G

Publication type:

journal article

Glucosamine activates the plasminogen activator inhibitor 1 gene promoter through Sp1 DNA binding sites in glomerular mesangial cells.

Published in:

2000

By:

Goldberg, Howard J.;
Scholey, James;
Fantus, I. George;
Goldberg, H J;
Scholey, J;
Fantus, I G

Publication type:

journal article

Tyrosine phosphatase inhibitors, vanadate and pervanadate, stimulate glucose transport and GLUT translocation in muscle cells by a mechanism independent of phosphatidylinositol 3-kinase and protein kinase C.

Published in:

1998

By:

Tsiani, Evangelia;
Bogdanovic, Elena;
Sorisky, Alexander;
Nagy, Laura;
Fantus, I. George;
Tsiani, E;
Bogdanovic, E;
Sorisky, A;
Nagy, L;
Fantus, I G

Publication type:

journal article

The insulin-mimetic agent vanadate promotes receptor endocytosis and inhibits intracellular ligand-receptor degradation by a mechanism distinct from the lysosomotropic agents.

Published in:

1996

By:

Fantus, I. George;
George, Rajan;
Shangguo Tang;
Chong, Paul;
Poznansky, Mark J.;
Fantus, I G;
George, R;
Tang, S;
Chong, P;
Poznansky, M J

Publication type:

journal article

Vanadate augments insulin-stimulated insulin receptor kinase activity and prolongs insulin action in rat adipocytes. Evidence for transduction of amplitude of signaling into duration of response.

Published in:

1994

By:

Fantus, I. George;
Ahmad, Ferhaan;
Deragon, Guy;
Fantus, I G;
Ahmad, F;
Deragon, G

Publication type:

journal article

Insulin binding and glucose transport in adipocytes in neonatal streptozocin-injected rat model of diabetes mellitus.

Published in:

1987

By:

Fantus, I. George;
Chayoth, Reuben;
O'Dea, Louis;
Marliss, Errol B.;
Yale, Jean-François;
Grose, Mark;
Fantus, I G;
Chayoth, R;
O'Dea, L;
Marliss, E B;
Yale, J F;
Grose, M

Publication type:

journal article

The Adaptor Protein p66Shc Inhibits mTOR-Dependent Anabolic Metabolism.

Published in:

Science Signaling, 2014, v. 7, n. 315, p. 1, doi. 10.1126/scisignal.2004785

By:

Soliman, Mohamed A.;
Rahman, Anas M. Abdel;
Lamming, Dudley A.;
Birsoy, Kivanç;
Pawling, Judy;
Frigolet, Maria E.;
Huogen Lu;
Fantus, I. George;
Pasculescu, Adrian;
Yong Zheng;
Sabatini, David M.;
Dennis, James W.;
Pawson, Tony

Publication type:

Article

The Adaptor Protein p66Shc Inhibits mTOR-Dependent Anabolic Metabolism.

Published in:

Science Signaling, 2014, v. 7, n. 313, p. 1, doi. 10.1126/scisignal.2004785

By:

Soliman, Mohamed A.;
Abdel Rahman, Anas M.;
Lamming, Dudley A.;
Birsoy, Kivanç;
Pawling, Judy;
Frigolet, Maria E.;
Lu, Huogen;
Fantus, I. George;
Pasculescu, Adrian;
Yong Zheng;
Sabatini, David M.;
Dennis, James W.;
Pawson, Tony

Publication type:

Article

Combined Hyperglycemia- and Hyperinsulinemia-Induced Insulin Resistance in Adipocytes Is Associated With Dual Signaling Defects Mediated by PKC-ζ.

Published in:

Endocrinology, 2018, v. 159, n. 4, p. 1658, doi. 10.1210/en.2017-00312

By:

Lu, Huogen;
Bogdanovic, Elena;
Yu, Zhiwen;
Cho, Charles;
Liu, Lijiang;
Ho, Karen;
Guo, June;
Yeung, Lucy S N;
Lehmann, Reiner;
Hundal, Harinder S;
Giacca, Adria;
Fantus, I George

Publication type:

Article

Genetic deletion of calcium-independent phospholipase A2γ protects mice from diabetic nephropathy.

Published in:

PLoS ONE, 2024, v. 19, n. 10, p. 1, doi. 10.1371/journal.pone.0311404

By:

Cybulsky, Andrey V.;
Papillon, Joan;
Guillemette, Julie;
Navarro-Betancourt, José R.;
Elimam, Hanan;
Fantus, I. George

Publication type:

Article

A Young Male with Parafibromin-Deficient Parathyroid Carcinoma Due to a Rare Germline HRPT2/CDC73 Mutation.

Published in:

Endocrine Pathology, 2018, v. 29, n. 4, p. 374, doi. 10.1007/s12022-018-9552-5

By:

Kapur, Alisha;
Singh, Narendra;
Mete, Ozgur;
Hegele, Robert A.;
Fantus, I. George

Publication type:

Article

Adverse immunologic effects of antithyroid drugs.

Published in:

Canadian Medical Association Journal (CMAJ), 1987, v. 136, n. 2, p. 121

By:

Wing, Simon S.;
Fantus, I. George

Publication type:

Article

Comparative effects of N-acetyl-l-cysteine and ramipril on arterial hypertension, insulin resistance, and oxidative stress in chronically glucose-fed rats.

Published in:

Canadian Journal of Physiology & Pharmacology, 2008, v. 86, n. 11, p. 752, doi. 10.1139/Y08-090

By:

El Midaoui, Adil;
Ismael, Mahmoud Ali;
Lu, Huogen;
Fantus, I. George;
de Champlain, Jacques;
Couture, Réjean

Publication type:

Article

Metformin's contraindications: needed for now.

Published in:

2005

By:

Fantus, I. George

Publication type:

journal article

Effect of thiazolidinediones on lipid profile.

Published in:

2005

By:

Cheng, Alice Y. Y.;
Fantus, I. George

Publication type:

Letter

Oral antihyperglycemic therapy for type 2 diabetes mellitus.

Published in:

Canadian Medical Association Journal (CMAJ), 2005, v. 172, n. 2, p. 213, doi. 10.1503/cmaj.1031414

By:

Cheng, Alice Y. Y.;
Fantus, I. George

Publication type:

Article

Is metformin ready for prime time in pregnancy? Probably not yet.

Published in:

Diabetes/Metabolism Research & Reviews, 2015, v. 31, n. 1, p. 36, doi. 10.1002/dmrr.2587

By:

Fantus, I. George

Publication type:

Article

Insulin's discovery: New insights on its ninetieth birthday.

Published in:

Diabetes/Metabolism Research & Reviews, 2012, v. 28, n. 4, p. 293, doi. 10.1002/dmrr.2300

By:

Roth, Jesse;
Qureshi, Sana;
Whitford, Ian;
Vranic, Mladen;
Kahn, C. Ronald;
Fantus, I. George;
Dirks, John H.

Publication type:

Article

Synchronous Health Care Delivery for the Optimization of Cardiovascular and Renal Care in Patients with Type 2 Diabetes.

Published in:

Current Cardiology Reports, 2022, v. 24, n. 8, p. 979, doi. 10.1007/s11886-022-01715-3

By:

Alqahtani, Mohammad;
Ganni, Elie;
Mavrakanas, Thomas;
Tsoukas, Michael;
Peters, Tricia;
Suri, Rita;
Fantus, I. George;
Pavilanis, Antonina;
Guida, Julian;
Razaghizad, Amir;
Sharma, Abhinav

Publication type:

Article

Inhibition of Src kinase blocks high glucose-induced EGFR transactivation and collagen synthesis in mesangial cells and prevents diabetic nephropathy in mice.

Published in:

2013

By:

Taniguchi, Kanta;
Xia, Ling;
Goldberg, Howard J;
Lee, Ken W K;
Shah, Anu;
Stavar, Laura;
Masson, Elodie A Y;
Momen, Abdul;
Shikatani, Eric A;
John, Rohan;
Husain, Mansoor;
Fantus, I George

Publication type:

journal article

Inhibition of Src Kinase Blocks High Glucose--Induced EGFR Transactivation and Collagen Synthesis in Mesangial Cells and Prevents Diabetic Nephropathy in Mice.

Published in:

Diabetes, 2013, v. 62, n. 11, p. 3874, doi. 10.2337/db12-1010

By:

Kanta Taniguchi;
Ling Xia;
Goldberg, Howard J.;
Lee, Ken W. K.;
Shah, Anu;
Stavar, Laura;
Masson, Elodie A. Y.;
Momen, Abdul;
Shikatani, Eric A.;
John, Rohan;
Husain, Mansoor;
Fantus, I. George

Publication type:

Article

Free Fatty Acid-Induced Reduction in Glucose-Stimulated Insulin Secretion.

Published in:

Diabetes, 2007, v. 56, n. 12, p. 2927, doi. 10.2337/db07-0075

By:

Oprescu, Andrei I.;
Bikopoulos, George;
Naassan, Anthony;
Allister, Emma M.;
Tang, Christine;
Park, Edward;
Uchino, Hiroshi;
Lewis, Gary F.;
Fantus, I. George;
Rozakis-Adcock, Maria;
Wheeler, Michael B.;
Giacca, Adria

Publication type:

Article

Bradykinin Sensitizes Rat Adipocytes to Insulin by Activation of Guanylate Cyclase/cGMP/Protein Kinase G and Inhibition of JNK and ERK1/2.

Published in:

Diabetes, 2007, v. 56, p. A348

By:

Beard, Kristin M.;
Deling Li;
Fantus, I. George

Publication type:

Article

Tumor Necrosis Factor-Alpha Converting Enzyme (TACE) Mediates High Glucose-Induced MAPK Activation in Rat Mesangial Cells.

Published in:

Diabetes, 2007, v. 56, p. A204

By:

Taniguchi, Kanta;
Goldberg, Howard;
Spiegelstein, Shlomit K.;
Fantus, I. George

Publication type:

Article

Effects of Alpha-Lipoic Acid on the Development of Arterial Hypertension, Type 2 Diabetes, Obesity and Vascular Oxidative Stress in Zucker Diabetic Fatty Rats.

Published in:

Diabetes, 2007, v. 56, p. A193

By:

El Midaoui, Adil;
De Champlain, Jacques;
Sadi, Almuktafi;
Husain, Mansoor;
Fantus, I. George

Publication type:

Article

Bradykinin Augments Insulin-Stimulated Glucose Transport in Rat Adipocytes via Endothelial Nitric Oxide Synthase-Mediated Inhibition of Jun NH2-Terminal Kinase.

Published in:

Diabetes, 2006, v. 55, n. 10, p. 2678, doi. 10.2337/db05-1538

By:

Beard, Kristin M.;
Huogen Lu;
Ho, Karen;
Fantus, I. George

Publication type:

Article

Rosiglitazone Prevents High Glucose-Induced Vascular Endothelial Growth Factor and Collagen IV Expression in Cultured Mesangial Cells.

Published in:

Experimental Diabetes Research, 2009, p. 1, doi. 10.1155/2009/910783

By:

Whiteside, Catharine;
Hong Wang;
Ling Xia;
Munk, Snezana;
Goldberg, Howard J.;
Fantus, I. George

Publication type:

Article

Beneficial Effects of Alpha-Lipoic Acid on Hypertension, Visceral Obesity, UCP-1 Expression and Oxidative Stress in Zucker Diabetic Fatty Rats.

Published in:

Antioxidants, 2019, v. 8, n. 12, p. 648, doi. 10.3390/antiox8120648

By:

El Midaoui, Adil;
Fantus, I. George;
Ait Boughrous, Ali;
Couture, Réjean

Publication type:

Article

New-onset diabetes mellitus associated with protease inhibitor therapy in an HIV-positive patient: case report and review.

Published in:

Canadian Medical Association Journal (CMAJ), 1999, v. 161, n. 2, p. 161

By:

Lee, Elmer C.C.;
Walmsley, Sharon;
Fantus, I. George

Publication type:

Article

Works by Fantus, I. George

Circulating Tumor Necrosis Factor-a Concentrations in a Native Canadian Population with High Rates of Type 2 Diabetes Mellitus.

Metformin in women with type 2 diabetes in pregnancy (MiTy): a multi-center randomized controlled trial.

Curcumin Prevents High Fat Diet Induced Insulin Resistance and Obesity via Attenuating Lipogenesis in Liver and Inflammatory Pathway in Adipocytes.

Gene and protein kinase expression profiling of reactive oxygen species-associated lipotoxicity in the pancreatic beta-cell line MIN6.

Gene and Protein Kinase Expression Profiling of Reactive Oxygen Species -- Associated Lipotoxicity in the Pancreatic β-Cell Line MIN6.

Decreased in situ insulin receptor dephosphorylation in hyperglycemia-induced insulin resistance in rat adipocytes.

Glucosamine activates the plasminogen activator inhibitor 1 gene promoter through Sp1 DNA binding sites in glomerular mesangial cells.

Tyrosine phosphatase inhibitors, vanadate and pervanadate, stimulate glucose transport and GLUT translocation in muscle cells by a mechanism independent of phosphatidylinositol 3-kinase and protein kinase C.

The insulin-mimetic agent vanadate promotes receptor endocytosis and inhibits intracellular ligand-receptor degradation by a mechanism distinct from the lysosomotropic agents.

Vanadate augments insulin-stimulated insulin receptor kinase activity and prolongs insulin action in rat adipocytes. Evidence for transduction of amplitude of signaling into duration of response.

Insulin binding and glucose transport in adipocytes in neonatal streptozocin-injected rat model of diabetes mellitus.

The Adaptor Protein p66Shc Inhibits mTOR-Dependent Anabolic Metabolism.

The Adaptor Protein p66Shc Inhibits mTOR-Dependent Anabolic Metabolism.

Combined Hyperglycemia- and Hyperinsulinemia-Induced Insulin Resistance in Adipocytes Is Associated With Dual Signaling Defects Mediated by PKC-ζ.

Genetic deletion of calcium-independent phospholipase A<sub>2</sub>γ protects mice from diabetic nephropathy.

A Young Male with Parafibromin-Deficient Parathyroid Carcinoma Due to a Rare Germline HRPT2/CDC73 Mutation.

Adverse immunologic effects of antithyroid drugs.

Comparative effects of N-acetyl-<span class="smallcap">l</span>-cysteine and ramipril on arterial hypertension, insulin resistance, and oxidative stress in chronically glucose-fed rats.

Metformin's contraindications: needed for now.

Effect of thiazolidinediones on lipid profile.

Oral antihyperglycemic therapy for type 2 diabetes mellitus.

Is metformin ready for prime time in pregnancy? Probably not yet.

Insulin's discovery: New insights on its ninetieth birthday.

Synchronous Health Care Delivery for the Optimization of Cardiovascular and Renal Care in Patients with Type 2 Diabetes.

Inhibition of Src kinase blocks high glucose-induced EGFR transactivation and collagen synthesis in mesangial cells and prevents diabetic nephropathy in mice.

Inhibition of Src Kinase Blocks High Glucose--Induced EGFR Transactivation and Collagen Synthesis in Mesangial Cells and Prevents Diabetic Nephropathy in Mice.

Free Fatty Acid-Induced Reduction in Glucose-Stimulated Insulin Secretion.

Bradykinin Sensitizes Rat Adipocytes to Insulin by Activation of Guanylate Cyclase/cGMP/Protein Kinase G and Inhibition of JNK and ERK1/2.

Tumor Necrosis Factor-Alpha Converting Enzyme (TACE) Mediates High Glucose-Induced MAPK Activation in Rat Mesangial Cells.

Effects of Alpha-Lipoic Acid on the Development of Arterial Hypertension, Type 2 Diabetes, Obesity and Vascular Oxidative Stress in Zucker Diabetic Fatty Rats.

Bradykinin Augments Insulin-Stimulated Glucose Transport in Rat Adipocytes via Endothelial Nitric Oxide Synthase-Mediated Inhibition of Jun NH<sub>2</sub>-Terminal Kinase.

Rosiglitazone Prevents High Glucose-Induced Vascular Endothelial Growth Factor and Collagen IV Expression in Cultured Mesangial Cells.

Beneficial Effects of Alpha-Lipoic Acid on Hypertension, Visceral Obesity, UCP-1 Expression and Oxidative Stress in Zucker Diabetic Fatty Rats.

New-onset diabetes mellitus associated with protease inhibitor therapy in an HIV-positive patient: case report and review.