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Arginine vasopressin release in response to the administration of 3,4-methylenedioxymethamphetamine ('ecstasy'): is metabolism a contributory factor?
Published in:
Journal of Pharmacy & Pharmacology, 2001, v. 53, n. 10, p. 1357, doi. 10.1211/0022357011777855
By:
- Forsling, Mary;
- Fallon, John K.;
- Kicman, Andrew T.;
- Hutt, Andrew J.;
- Cowan, David A.;
- Henry, John A.
Publication type:
Article
UGT concentrations in human rectal tissue after multidose, oral curcumin.
Published in:
Pharmacology Research & Perspectives, 2016, v. 4, n. 2, p. n/a, doi. 10.1002/prp2.222
By:
- Asher, Gary N.;
- Fallon, John K.;
- Smith, Philip C.
Publication type:
Article
Impact of pregnancy related hormones on drug metabolizing enzyme and transport protein concentrations in human hepatocytes.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1004010
By:
- Fashe, Muluneh M.;
- Fallon, John K.;
- Miner, Taryn A.;
- Tiley, Jacqueline B.;
- Smith, Philip C.;
- Lee, Craig R.
Publication type:
Article
A novel differentiated HuH-7 cell model to examine bile acid metabolism, transport and cholestatic hepatotoxicity.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-18174-z
By:
- Saran, Chitra;
- Fu, Dong;
- Ho, Henry;
- Klein, Abigail;
- Fallon, John K.;
- Honkakoski, Paavo;
- Brouwer, Kim L. R.
Publication type:
Article
The effect of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') and its metabolites on neurohypophysical hormone release from the isolated rat hypothalamus.
Published in:
British Journal of Pharmacology, 2002, v. 135, n. 3, p. 649, doi. 10.1038/sj.bjp.0704502
By:
- Forsling, Mary L.;
- Fallon, John K.;
- Shah, Darshna;
- Tilbrook, Gary S.;
- Cowan, David A.;
- Kicman, Andrew T.;
- Hutt, Andrew J.
Publication type:
Article
Pregnancy-Related Hormones Increase UGT1A1-Mediated Labetalol Metabolism in Human Hepatocytes.
Published in:
Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.655320
By:
- Khatri, Raju;
- Fallon, John K.;
- Sykes, Craig;
- Kulick, Natasha;
- Rementer, Rebecca J. B.;
- Miner, Taryn A.;
- Schauer, Amanda P.;
- Kashuba, Angela D. M.;
- Boggess, Kim A.;
- Brouwer, Kim L. R.;
- Smith, Philip C.;
- Lee, Craig R.
Publication type:
Article
Expansion of Knowledge on OCT1 Variant Activity In Vitro and In Vivo Using Oct1/2<sup>−/−</sup> Mice.
Published in:
Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.631793
By:
- Morse, Bridget L.;
- Chen, Lisa Hong;
- Catlow, John T.;
- Fallon, John K.;
- Smith, Philip C.;
- Hillgren, Kathleen M.
Publication type:
Article
Sinusoidal Organic Anion-Transporting Polypeptide 1B1/1B3 and Bile Canalicular Multidrug Resistance-Associated Protein 2 Play an Essential Role in the Hepatobiliary Disposition of a Synthetic Cyclic Dinucleotide (STING Agonist).
Published in:
AAPS Journal, 2022, v. 24, n. 6, p. 1, doi. 10.1208/s12248-022-00745-7
By:
- Sandoval, Philip;
- Chuang, Bei-Ching;
- Fallon, John K.;
- Smith, Philip C.;
- Chowdhury, Swapan K.;
- Griffin, Robert J.;
- Xia, Cindy Q.;
- Iwasaki, Shinji;
- Chothe, Paresh P.
Publication type:
Article
Comparison of Hepatic Transporter Tissue Expression in Rodents and Interspecies Hepatic OCT1 Activity.
Published in:
AAPS Journal, 2021, v. 23, n. 3, p. 1, doi. 10.1208/s12248-021-00583-z
By:
- Morse, Bridget L.;
- Fallon, John K.;
- Kolur, Anil;
- Hogan, Andrew T.;
- Smith, Philip C.;
- Hillgren, Kathleen M.
Publication type:
Article
Scaling factors for the in vitro- in vivo extrapolation (IV-IVE) of renal drug and xenobiotic glucuronidation clearance.
Published in:
British Journal of Clinical Pharmacology, 2016, v. 81, n. 6, p. 1153, doi. 10.1111/bcp.12889
By:
- Knights, Kathleen M.;
- Spencer, Shane M.;
- Fallon, John K.;
- Chau, Nuy;
- Smith, Philip C.;
- Miners, John O.
Publication type:
Article
Evaluation of human primary intestinal monolayers for drug metabolizing capabilities.
Published in:
Journal of Biological Engineering, 2019, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13036-019-0212-1
By:
- Speer, Jennifer E.;
- Wang, Yuli;
- Fallon, John K.;
- Smith, Philip C.;
- Allbritton, Nancy L.
Publication type:
Article
Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking.
Published in:
Journal of Biological Engineering, 2019, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13036-019-0165-4
By:
- Speer, Jennifer E.;
- Gunasekara, Dulan B.;
- Wang, Yuli;
- Fallon, John K.;
- Attayek, Peter J.;
- Smith, Philip C.;
- Sims, Christopher E.;
- Allbritton, Nancy L.
Publication type:
Article
Impact of Pregnancy on the Pharmacokinetics and Metabolism of Nicotinamide in Humans.
Published in:
Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 3, p. 556, doi. 10.1002/cpt.3146
By:
- Fashe, Muluneh M.;
- Le, Tien V.;
- Gower, Megan N.;
- Mulrenin, Ian R.;
- Dorman, Karen F.;
- Smith, Spenser;
- Fallon, John K.;
- Dumond, Julie B.;
- Boggess, Kim A.;
- Lee, Craig R.
Publication type:
Article
Using Extracellular Vesicles Released by GDNF-Transfected Macrophages for Therapy of Parkinson Disease.
Published in:
Cells (2073-4409), 2022, v. 11, n. 12, p. 1933, doi. 10.3390/cells11121933
By:
- Zhao, Yuling;
- Haney, Matthew J.;
- Fallon, John K.;
- Rodriguez, Myosotys;
- Swain, Carson J.;
- Arzt, Camryn J.;
- Smith, Philip C.;
- Loop, Matthew Shane;
- Harrison, Emily B.;
- El-Hage, Nazira;
- Batrakova, Elena V.
Publication type:
Article
Pregnancy related hormones increase CYP3A mediated buprenorphine metabolism in human hepatocytes: a comparison to CYP3A substrates nifedipine and midazolam.
Published in:
Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1218703
By:
- Fashe, Muluneh M.;
- Miner, Taryn A.;
- Fallon, John K.;
- Schauer, Amanda P.;
- Sykes, Craig;
- Smith, Philip C.;
- Lee, Craig R.
Publication type:
Article
Formation of CYP3A‐specific metabolites of ibrutinib in vitro is correlated with hepatic CYP3A activity and 4β‐hydroxycholesterol/cholesterol ratio.
Published in:
CTS: Clinical & Translational Science, 2023, v. 16, n. 2, p. 279, doi. 10.1111/cts.13448
By:
- Lee, Jonghwa;
- Fallon, John K.;
- Smith, Philip C.;
- Jackson, Klarissa D.
Publication type:
Article
A phase I evaluation of the effect of curcumin on dose‐limiting toxicity and pharmacokinetics of irinotecan in participants with solid tumors.
Published in:
CTS: Clinical & Translational Science, 2022, v. 15, n. 5, p. 1304, doi. 10.1111/cts.13250
By:
- Gbolahan, Olumide B.;
- O'Neil, Bert H.;
- McRee, Autumn J.;
- Sanoff, Hanna K.;
- Fallon, John K.;
- Smith, Philip C.;
- Ivanova, Anastasia;
- Moore, Dominic T.;
- Dumond, Julie;
- Asher, Gary N.
Publication type:
Article
Role of Organic Solute Transporter Alpha/Beta in Hepatotoxic Bile Acid Transport and Drug Interactions.
Published in:
Toxicological Sciences, 2020, v. 176, n. 1, p. 34, doi. 10.1093/toxsci/kfaa052
By:
- Beaudoin, James J;
- Bezençon, Jacqueline;
- Sjöstedt, Noora;
- Fallon, John K;
- Brouwer, Kim L R
Publication type:
Article
Extreme low dose of 5-fluorouracil reverses MDR in cancer by sensitizing cancer associated fibroblasts and down-regulating P-gp.
Published in:
PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0180023
By:
- Ma, Yan;
- Wang, Yuhua;
- Xu, Zhenghong;
- Wang, Yongjun;
- Fallon, John K.;
- Liu, Feng
Publication type:
Article
New mouse xenograft model modulated by tumor-associated fibroblasts for human multi-drug resistance in cancer.
Published in:
Oncology Reports, 2015, v. 34, n. 5, p. 2699, doi. 10.3892/or.2015.4265
By:
- YAN MA;
- ZHIQIANG LIN;
- FALLON, JOHN K.;
- QIANG ZHAO;
- DAN LIU;
- YONGJUN WANG;
- FENG LIU
Publication type:
Article

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