Works by Falck, David

Results: 29

A functional spleen contributes to afucosylated IgG in humans.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-03196-w

By:

Wojcik, Iwona;
Schmidt, David E.;
de Neef, Lisa A.;
Rab, Minke A. E.;
Meek, Bob;
de Weerdt, Okke;
Wuhrer, Manfred;
van der Schoot, C. Ellen;
Zwaginga, Jaap J.;
de Haas, Masja;
Falck, David;
Vidarsson, Gestur

Publication type:

Article

Glycosylation signature of plasma IgA of critically ill COVID-19 patients.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1439248

By:

Potaczek, Daniel P.;
van Tol, Bianca D. M.;
Falck, David;
Krolczik, Christina;
Zlatina, Kristina;
Bertrams, Wilhelm;
Wilhelm, Jochen;
Schmeck, Bernd;
Seeliger, Benjamin;
David, Sascha;
Skevaki, Chrysanthi;
Mack, Elisabeth;
Seeger, Werner;
Schaefer, Liliana;
Galuska, Sebastian P.;
Wuhrer, Manfred;
Wygrecka, Małgorzata

Publication type:

Article

Benchmarking glycoform-resolved affinity separation - mass spectrometry assays for studying FcγRIIIa binding.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1347871

By:

Gstöttner, Christoph;
Lippold, Steffen;
Hook, Michaela;
Feng Yang;
Haberger, Markus;
Wuhrer, Manfred;
Falck, David;
Schlothauer, Tilman;
Domínguez-Vega, Elena

Publication type:

Article

GlycoDash: automated, visually assisted curation of glycoproteomics datasets for large sample numbers: GlycoDash: automated, visually assisted curation of glycoproteomics datasets for large sample numbers: T. Pongracz et al.

Published in:

Analytical & Bioanalytical Chemistry, 2025, v. 417, n. 10, p. 2003, doi. 10.1007/s00216-025-05794-3

By:

Pongracz, Tamas;
Gijze, Steinar;
Hipgrave Ederveen, Agnes L.;
Derks, Rico J. E.;
Falck, David

Publication type:

Article

Clearance of therapeutic antibody glycoforms after subcutaneous and intravenous injection in a porcine model.

Published in:

2022

By:

Falck, David;
Lechmann, Martin;
Momčilović, Ana;
Thomann, Marco;
Koeleman, Carolien A. M.;
Jany, Cordula;
Malik, Sebastian;
Wuhrer, Manfred;
Reusch, Dietmar

Publication type:

Report

Fc gamma receptor IIIb binding of individual antibody proteoforms resolved by affinity chromatography–mass spectrometry.

Published in:

2021

By:

Lippold, Steffen;
Knaupp, Alexander;
de Ru, Arnoud H.;
Tjokrodirijo, Rayman T. N.;
van Veelen, Peter A.;
van Puijenbroek, Erwin;
de Taeye, Steven W.;
Reusch, Dietmar;
Vidarsson, Gestur;
Wuhrer, Manfred;
Schlothauer, Tilman;
Falck, David

Publication type:

Report

Glycoform-resolved pharmacokinetic studies in a rat model employing glycoengineered variants of a therapeutic monoclonal antibody.

Published in:

2021

By:

Falck, David;
Thomann, Marco;
Lechmann, Martin;
Koeleman, Carolien A. M.;
Malik, Sebastian;
Jany, Cordula;
Wuhrer, Manfred;
Reusch, Dietmar

Publication type:

Report

Glycoform-resolved FcɣRIIIa affinity chromatography–mass spectrometry.

Published in:

mAbs (1942-0862), 2019, v. 11, n. 7, p. 1191, doi. 10.1080/19420862.2019.1636602

By:

Lippold, Steffen;
Nicolardi, Simone;
Domínguez-Vega, Elena;
Heidenreich, Anna-Katharina;
Vidarsson, Gestur;
Reusch, Dietmar;
Haberger, Markus;
Wuhrer, Manfred;
Falck, David

Publication type:

Article

Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles—Part 2: Mass spectrometric methods.

Published in:

mAbs (1942-0862), 2015, v. 7, n. 4, p. 732, doi. 10.1080/19420862.2015.1045173

By:

Reusch, Dietmar;
Haberger, Markus;
Falck, David;
Peter, Britta;
Maier, Bernd;
Gassner, Jana;
Hook, Michaela;
Wagner, Katharina;
Bonnington, Lea;
Bulau, Patrick;
Wuhrer, Manfred

Publication type:

Article

A novel glycosidase plate-based assay for the quantification of galactosylation and sialylation on human IgG.

Published in:

Glycoconjugate Journal, 2020, v. 37, n. 6, p. 691, doi. 10.1007/s10719-020-09953-9

By:

Rebello, Osmond D.;
Gardner, Richard A.;
Urbanowicz, Paulina A.;
Bolam, David N.;
Crouch, Lucy I.;
Falck, David;
Spencer, Daniel I. R.

Publication type:

Article

Afucosylated broadly neutralizing antibodies enhance clearance of HIV-1 infected cells through cell-mediated killing.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06659-8

By:

de Taeye, Steven W.;
Schriek, Angela I.;
Umotoy, Jeffrey C.;
Grobben, Marloes;
Burger, Judith A.;
Sanders, Rogier W.;
Vidarsson, Gestur;
Wuhrer, Manfred;
Falck, David;
Kootstra, Neeltje A.;
van Gils, Marit J.

Publication type:

Article

Pregnancy-associated serum N-glycome changes studied by high-throughput MALDI-TOF-MS.

Published in:

Scientific Reports, 2016, p. 23296, doi. 10.1038/srep23296

By:

Jansen, Bas C.;
Bondt, Albert;
Reiding, Karli R.;
Lonardi, Emanuela;
de Jong, Coen J.;
Falck, David;
Kammeijer, Guinevere S. M.;
Dolhain, Radboud J. E. M.;
Rombouts, Yoann;
Wuhrer, Manfred

Publication type:

Article

Erythropoietin N -glycosylation of Therapeutic Formulations Quantified and Characterized: An Interlab Comparability Study of High-Throughput Methods.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 1, p. 125, doi. 10.3390/biom14010125

By:

O'Flaherty, Róisín;
Amez Martín, Manuela;
Gardner, Richard A.;
Jennings, Patrick M.;
Rudd, Pauline M.;
Spencer, Daniel I. R.;
Falck, David

Publication type:

Article

MS-Based Allotype-Specific Analysis of Polyclonal IgG-Fc N -Glycosylation.

Published in:

Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.02049

By:

Sénard, Thomas;
Gargano, Andrea F. G.;
Falck, David;
de Taeye, Steven W.;
Rispens, Theo;
Vidarsson, Gestur;
Wuhrer, Manfred;
Somsen, Govert W.;
Domínguez-Vega, Elena

Publication type:

Article

FcγR Binding and ADCC Activity of Human IgG Allotypes.

Published in:

Frontiers in Immunology, 2020, v. 11, p. 1, doi. 10.3389/fimmu.2020.00740

By:

de Taeye, Steven W.;
Bentlage, Arthur E. H.;
Mebius, Mirjam M.;
Meesters, Joyce I.;
Lissenberg-Thunnissen, Suzanne;
Falck, David;
Sénard, Thomas;
Salehi, Nima;
Wuhrer, Manfred;
Schuurman, Janine;
Labrijn, Aran F.;
Rispens, Theo;
Vidarsson, Gestur

Publication type:

Article

ASGR1 deficiency improves atherosclerosis but alters liver metabolism in ApoE<sup>-/-</sup> mice.

Published in:

Cardiovascular Diabetology, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12933-024-02507-5

By:

Svecla, Monika;
Moregola, Annalisa;
Dalt, Lorenzo Da;
Nour, Jasmine;
Baragetti, Andrea;
Uboldi, Patrizia;
Idini, Alessandra;
Wuhrer, Manfred;
Beretta, Giangiacomo;
Falck, David;
Bonacina, Fabrizia;
Norata, Giuseppe Danilo

Publication type:

Article

Metabolic profiling of ligands for the chemokine receptor CXCR3 by liquid chromatography-mass spectrometry coupled to bioaffinity assessment.

Published in:

Analytical & Bioanalytical Chemistry, 2015, v. 407, n. 23, p. 7067, doi. 10.1007/s00216-015-8867-z

By:

Mladic, Marija;
Scholten, Danny;
Wijtmans, Maikel;
Falck, David;
Leurs, Rob;
Niessen, Wilfried;
Smit, Martine;
Kool, Jeroen

Publication type:

Article

Comparison of Fc N-Glycosylation of Pharmaceutical Products of Intravenous Immunoglobulin G.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0139828

By:

Fokkink, Willem Jan R.;
Falck, David;
Santbergen, Tom C. M.;
Huizinga, Ruth;
Wuhrer, Manfred;
Jacobs, Bart C.

Publication type:

Article

IgA subclasses have different effector functions associated with distinct glycosylation profiles.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-019-13992-8

By:

Steffen, Ulrike;
Koeleman, Carolien A.;
Sokolova, Maria V.;
Bang, Holger;
Kleyer, Arnd;
Rech, Jürgen;
Unterweger, Harald;
Schicht, Martin;
Garreis, Fabian;
Hahn, Jonas;
Andes, Fabian T.;
Hartmann, Fabian;
Hahn, Madelaine;
Mahajan, Aparna;
Paulsen, Friedrich;
Hoffmann, Markus;
Lochnit, Günter;
Muñoz, Luis E.;
Wuhrer, Manfred;
Falck, David

Publication type:

Article

Highly sensitive CE-ESI-MS analysis of N-glycans from complex biological samples.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09910-7

By:

Lageveen-Kammeijer, Guinevere S. M.;
de Haan, Noortje;
Mohaupt, Pablo;
Wagt, Sander;
Filius, Mike;
Nouta, Jan;
Falck, David;
Wuhrer, Manfred

Publication type:

Article

EC-SPE-stripline-NMR analysis of reactive products: a feasibility study.

Published in:

Analytical & Bioanalytical Chemistry, 2013, v. 405, n. 21, p. 6711, doi. 10.1007/s00216-013-7158-9

By:

Falck, David;
Oosthoek-de Vries, Anna;
Kolkman, Ard;
Lingeman, Henk;
Honing, Maarten;
Wijmenga, Sybren;
Kentgens, Arno;
Niessen, Wilfried

Publication type:

Article

On-line electrochemistry-bioaffinity screening with parallel HR-LC-MS for the generation and characterization of modified p38α kinase inhibitors.

Published in:

Analytical & Bioanalytical Chemistry, 2012, v. 403, n. 2, p. 367, doi. 10.1007/s00216-011-5663-2

By:

Falck, David;
Vlieger, Jon;
Giera, Martin;
Honing, Maarten;
Irth, Hubertus;
Niessen, Wilfried;
Kool, Jeroen

Publication type:

Article

Development of an online p38α mitogen-activated protein kinase binding assay and integration of LC-HR-MS.

Published in:

Analytical & Bioanalytical Chemistry, 2010, v. 398, n. 4, p. 1771, doi. 10.1007/s00216-010-4087-8

By:

Falck, David;
De Vlieger, Jon S. B.;
Niessen, Wilfried M. A.;
Kool, Jeroen;
Honing, Maarten;
Giera, Martin;
Irth, Hubertus

Publication type:

Article

Specific IgG glycosylation differences precede relapse in PR3-ANCA associated vasculitis patients with and without ANCA rise.

Published in:

Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1214945

By:

Wojcik, Iwona;
Wuhrer, Manfred;
Heeringa, Peter;
Stegeman, Coen A.;
Rutgers, Abraham;
Falck, David

Publication type:

Article

GlYcoLISA: antigen-specific and subclass-specific IgG Fc glycosylation analysis based on an immunosorbent assay with an LC–MS readout.

Published in:

Nature Protocols, 2024, v. 19, n. 6, p. 1887, doi. 10.1038/s41596-024-00963-7

By:

Falck, David;
Wuhrer, Manfred

Publication type:

Article

Developments and perspectives in high-throughput protein glycomics: enabling the analysis of thousands of samples.

Published in:

Glycobiology, 2022, v. 32, n. 8, p. 651, doi. 10.1093/glycob/cwac026

By:

Haan, Noortje de;
Pučić-Baković, Maja;
Novokmet, Mislav;
Falck, David;
Lageveen-Kammeijer, Guinevere;
Razdorov, Genadij;
Vučković, Frano;
Trbojević-Akmačić, Irena;
Gornik, Olga;
Hanić, Maja;
Wuhrer, Manfred;
Lauc, Gordan;
Project, the The Human Glycome

Publication type:

Article

Monitoring of immunoglobulin N- and O-glycosylation in health and disease.

Published in:

Glycobiology, 2020, v. 30, n. 4, p. 226, doi. 10.1093/glycob/cwz048

By:

Haan, Noortje de;
Falck, David;
Wuhrer, Manfred

Publication type:

Article

Editorial: Immunoglobulin Glycosylation Analysis: State-of-the-Art Methods and Applications in Immunology.

Published in:

2022

By:

Trbojević-Akmačić, Irena;
Abdel-Mohsen, Mohamed;
Falck, David;
Rapp, Erdmann

Publication type:

Editorial

IgA displays site- and subclass-specific glycoform differences despite equal glycoenzyme expression.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02088-0

By:

Falck, David;
Sokolova, Maria V.;
Koeleman, Carolien A. M.;
Irumva, Vanessa;
Kirchner, Philipp;
Schulz, Sebastian R.;
Schmidt, Katja G.;
Harrer, Thomas;
Ekici, Arif B.;
Spriewald, Bernd;
Schett, Georg;
Wuhrer, Manfred;
Herrmann, Martin;
Steffen, Ulrike

Publication type:

Article