Works by Falck, David

Results: 28

Developments and perspectives in high-throughput protein glycomics: enabling the analysis of thousands of samples.
Published in:
Glycobiology, 2022, v. 32, n. 8, p. 651, doi. 10.1093/glycob/cwac026
By:
- Haan, Noortje de;
- Pučić-Baković, Maja;
- Novokmet, Mislav;
- Falck, David;
- Lageveen-Kammeijer, Guinevere;
- Razdorov, Genadij;
- Vučković, Frano;
- Trbojević-Akmačić, Irena;
- Gornik, Olga;
- Hanić, Maja;
- Wuhrer, Manfred;
- Lauc, Gordan;
- Project, the The Human Glycome
Publication type:
Article
Monitoring of immunoglobulin N- and O-glycosylation in health and disease.
Published in:
Glycobiology, 2020, v. 30, n. 4, p. 226, doi. 10.1093/glycob/cwz048
By:
- Haan, Noortje de;
- Falck, David;
- Wuhrer, Manfred
Publication type:
Article
Erythropoietin N -glycosylation of Therapeutic Formulations Quantified and Characterized: An Interlab Comparability Study of High-Throughput Methods.
Published in:
Biomolecules (2218-273X), 2024, v. 14, n. 1, p. 125, doi. 10.3390/biom14010125
By:
- O'Flaherty, Róisín;
- Amez Martín, Manuela;
- Gardner, Richard A.;
- Jennings, Patrick M.;
- Rudd, Pauline M.;
- Spencer, Daniel I. R.;
- Falck, David
Publication type:
Article
A novel glycosidase plate-based assay for the quantification of galactosylation and sialylation on human IgG.
Published in:
Glycoconjugate Journal, 2020, v. 37, n. 6, p. 691, doi. 10.1007/s10719-020-09953-9
By:
- Rebello, Osmond D.;
- Gardner, Richard A.;
- Urbanowicz, Paulina A.;
- Bolam, David N.;
- Crouch, Lucy I.;
- Falck, David;
- Spencer, Daniel I. R.
Publication type:
Article
GlYcoLISA: antigen-specific and subclass-specific IgG Fc glycosylation analysis based on an immunosorbent assay with an LC–MS readout.
Published in:
Nature Protocols, 2024, v. 19, n. 6, p. 1887, doi. 10.1038/s41596-024-00963-7
By:
- Falck, David;
- Wuhrer, Manfred
Publication type:
Article
IgA displays site- and subclass-specific glycoform differences despite equal glycoenzyme expression.
Published in:
Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02088-0
By:
- Falck, David;
- Sokolova, Maria V.;
- Koeleman, Carolien A. M.;
- Irumva, Vanessa;
- Kirchner, Philipp;
- Schulz, Sebastian R.;
- Schmidt, Katja G.;
- Harrer, Thomas;
- Ekici, Arif B.;
- Spriewald, Bernd;
- Schett, Georg;
- Wuhrer, Manfred;
- Herrmann, Martin;
- Steffen, Ulrike
Publication type:
Article
Editorial: Immunoglobulin Glycosylation Analysis: State-of-the-Art Methods and Applications in Immunology.
Published in:
2022
By:
- Trbojević-Akmačić, Irena;
- Abdel-Mohsen, Mohamed;
- Falck, David;
- Rapp, Erdmann
Publication type:
Editorial
Afucosylated broadly neutralizing antibodies enhance clearance of HIV-1 infected cells through cell-mediated killing.
Published in:
Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06659-8
By:
- de Taeye, Steven W.;
- Schriek, Angela I.;
- Umotoy, Jeffrey C.;
- Grobben, Marloes;
- Burger, Judith A.;
- Sanders, Rogier W.;
- Vidarsson, Gestur;
- Wuhrer, Manfred;
- Falck, David;
- Kootstra, Neeltje A.;
- van Gils, Marit J.
Publication type:
Article
Glycosylation signature of plasma IgA of critically ill COVID-19 patients.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1439248
By:
- Potaczek, Daniel P.;
- van Tol, Bianca D. M.;
- Falck, David;
- Krolczik, Christina;
- Zlatina, Kristina;
- Bertrams, Wilhelm;
- Wilhelm, Jochen;
- Schmeck, Bernd;
- Seeliger, Benjamin;
- David, Sascha;
- Skevaki, Chrysanthi;
- Mack, Elisabeth;
- Seeger, Werner;
- Schaefer, Liliana;
- Galuska, Sebastian P.;
- Wuhrer, Manfred;
- Wygrecka, Małgorzata
Publication type:
Article
Benchmarking glycoform-resolved affinity separation - mass spectrometry assays for studying FcγRIIIa binding.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1347871
By:
- Gstöttner, Christoph;
- Lippold, Steffen;
- Hook, Michaela;
- Feng Yang;
- Haberger, Markus;
- Wuhrer, Manfred;
- Falck, David;
- Schlothauer, Tilman;
- Domínguez-Vega, Elena
Publication type:
Article
Comparison of Fc N-Glycosylation of Pharmaceutical Products of Intravenous Immunoglobulin G.
Published in:
PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0139828
By:
- Fokkink, Willem Jan R.;
- Falck, David;
- Santbergen, Tom C. M.;
- Huizinga, Ruth;
- Wuhrer, Manfred;
- Jacobs, Bart C.
Publication type:
Article
A functional spleen contributes to afucosylated IgG in humans.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-03196-w
By:
- Wojcik, Iwona;
- Schmidt, David E.;
- de Neef, Lisa A.;
- Rab, Minke A. E.;
- Meek, Bob;
- de Weerdt, Okke;
- Wuhrer, Manfred;
- van der Schoot, C. Ellen;
- Zwaginga, Jaap J.;
- de Haas, Masja;
- Falck, David;
- Vidarsson, Gestur
Publication type:
Article
Pregnancy-associated serum N-glycome changes studied by high-throughput MALDI-TOF-MS.
Published in:
Scientific Reports, 2016, p. 23296, doi. 10.1038/srep23296
By:
- Jansen, Bas C.;
- Bondt, Albert;
- Reiding, Karli R.;
- Lonardi, Emanuela;
- de Jong, Coen J.;
- Falck, David;
- Kammeijer, Guinevere S. M.;
- Dolhain, Radboud J. E. M.;
- Rombouts, Yoann;
- Wuhrer, Manfred
Publication type:
Article
FcγR Binding and ADCC Activity of Human IgG Allotypes.
Published in:
Frontiers in Immunology, 2020, v. 11, p. 1, doi. 10.3389/fimmu.2020.00740
By:
- de Taeye, Steven W.;
- Bentlage, Arthur E. H.;
- Mebius, Mirjam M.;
- Meesters, Joyce I.;
- Lissenberg-Thunnissen, Suzanne;
- Falck, David;
- Sénard, Thomas;
- Salehi, Nima;
- Wuhrer, Manfred;
- Schuurman, Janine;
- Labrijn, Aran F.;
- Rispens, Theo;
- Vidarsson, Gestur
Publication type:
Article
Metabolic profiling of ligands for the chemokine receptor CXCR3 by liquid chromatography-mass spectrometry coupled to bioaffinity assessment.
Published in:
Analytical & Bioanalytical Chemistry, 2015, v. 407, n. 23, p. 7067, doi. 10.1007/s00216-015-8867-z
By:
- Mladic, Marija;
- Scholten, Danny;
- Wijtmans, Maikel;
- Falck, David;
- Leurs, Rob;
- Niessen, Wilfried;
- Smit, Martine;
- Kool, Jeroen
Publication type:
Article
EC-SPE-stripline-NMR analysis of reactive products: a feasibility study.
Published in:
Analytical & Bioanalytical Chemistry, 2013, v. 405, n. 21, p. 6711, doi. 10.1007/s00216-013-7158-9
By:
- Falck, David;
- Oosthoek-de Vries, Anna;
- Kolkman, Ard;
- Lingeman, Henk;
- Honing, Maarten;
- Wijmenga, Sybren;
- Kentgens, Arno;
- Niessen, Wilfried
Publication type:
Article
On-line electrochemistry-bioaffinity screening with parallel HR-LC-MS for the generation and characterization of modified p38α kinase inhibitors.
Published in:
Analytical & Bioanalytical Chemistry, 2012, v. 403, n. 2, p. 367, doi. 10.1007/s00216-011-5663-2
By:
- Falck, David;
- Vlieger, Jon;
- Giera, Martin;
- Honing, Maarten;
- Irth, Hubertus;
- Niessen, Wilfried;
- Kool, Jeroen
Publication type:
Article
Development of an online p38α mitogen-activated protein kinase binding assay and integration of LC-HR-MS.
Published in:
Analytical & Bioanalytical Chemistry, 2010, v. 398, n. 4, p. 1771, doi. 10.1007/s00216-010-4087-8
By:
- Falck, David;
- De Vlieger, Jon S. B.;
- Niessen, Wilfried M. A.;
- Kool, Jeroen;
- Honing, Maarten;
- Giera, Martin;
- Irth, Hubertus
Publication type:
Article
IgA subclasses have different effector functions associated with distinct glycosylation profiles.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-019-13992-8
By:
- Steffen, Ulrike;
- Koeleman, Carolien A.;
- Sokolova, Maria V.;
- Bang, Holger;
- Kleyer, Arnd;
- Rech, Jürgen;
- Unterweger, Harald;
- Schicht, Martin;
- Garreis, Fabian;
- Hahn, Jonas;
- Andes, Fabian T.;
- Hartmann, Fabian;
- Hahn, Madelaine;
- Mahajan, Aparna;
- Paulsen, Friedrich;
- Hoffmann, Markus;
- Lochnit, Günter;
- Muñoz, Luis E.;
- Wuhrer, Manfred;
- Falck, David
Publication type:
Article
Highly sensitive CE-ESI-MS analysis of N-glycans from complex biological samples.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09910-7
By:
- Lageveen-Kammeijer, Guinevere S. M.;
- de Haan, Noortje;
- Mohaupt, Pablo;
- Wagt, Sander;
- Filius, Mike;
- Nouta, Jan;
- Falck, David;
- Wuhrer, Manfred
Publication type:
Article
Specific IgG glycosylation differences precede relapse in PR3-ANCA associated vasculitis patients with and without ANCA rise.
Published in:
Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1214945
By:
- Wojcik, Iwona;
- Wuhrer, Manfred;
- Heeringa, Peter;
- Stegeman, Coen A.;
- Rutgers, Abraham;
- Falck, David
Publication type:
Article
MS-Based Allotype-Specific Analysis of Polyclonal IgG-Fc N -Glycosylation.
Published in:
Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.02049
By:
- Sénard, Thomas;
- Gargano, Andrea F. G.;
- Falck, David;
- de Taeye, Steven W.;
- Rispens, Theo;
- Vidarsson, Gestur;
- Wuhrer, Manfred;
- Somsen, Govert W.;
- Domínguez-Vega, Elena
Publication type:
Article
Clearance of therapeutic antibody glycoforms after subcutaneous and intravenous injection in a porcine model.
Published in:
2022
By:
- Falck, David;
- Lechmann, Martin;
- Momčilović, Ana;
- Thomann, Marco;
- Koeleman, Carolien A. M.;
- Jany, Cordula;
- Malik, Sebastian;
- Wuhrer, Manfred;
- Reusch, Dietmar
Publication type:
Report
Fc gamma receptor IIIb binding of individual antibody proteoforms resolved by affinity chromatography–mass spectrometry.
Published in:
2021
By:
- Lippold, Steffen;
- Knaupp, Alexander;
- de Ru, Arnoud H.;
- Tjokrodirijo, Rayman T. N.;
- van Veelen, Peter A.;
- van Puijenbroek, Erwin;
- de Taeye, Steven W.;
- Reusch, Dietmar;
- Vidarsson, Gestur;
- Wuhrer, Manfred;
- Schlothauer, Tilman;
- Falck, David
Publication type:
Report
Glycoform-resolved pharmacokinetic studies in a rat model employing glycoengineered variants of a therapeutic monoclonal antibody.
Published in:
2021
By:
- Falck, David;
- Thomann, Marco;
- Lechmann, Martin;
- Koeleman, Carolien A. M.;
- Malik, Sebastian;
- Jany, Cordula;
- Wuhrer, Manfred;
- Reusch, Dietmar
Publication type:
Report
Glycoform-resolved FcɣRIIIa affinity chromatography–mass spectrometry.
Published in:
mAbs, 2019, v. 11, n. 7, p. 1191, doi. 10.1080/19420862.2019.1636602
By:
- Lippold, Steffen;
- Nicolardi, Simone;
- Domínguez-Vega, Elena;
- Heidenreich, Anna-Katharina;
- Vidarsson, Gestur;
- Reusch, Dietmar;
- Haberger, Markus;
- Wuhrer, Manfred;
- Falck, David
Publication type:
Article
Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles—Part 2: Mass spectrometric methods.
Published in:
mAbs, 2015, v. 7, n. 4, p. 732, doi. 10.1080/19420862.2015.1045173
By:
- Reusch, Dietmar;
- Haberger, Markus;
- Falck, David;
- Peter, Britta;
- Maier, Bernd;
- Gassner, Jana;
- Hook, Michaela;
- Wagner, Katharina;
- Bonnington, Lea;
- Bulau, Patrick;
- Wuhrer, Manfred
Publication type:
Article
ASGR1 deficiency improves atherosclerosis but alters liver metabolism in ApoE<sup>-/-</sup> mice.
Published in:
Cardiovascular Diabetology, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12933-024-02507-5
By:
- Svecla, Monika;
- Moregola, Annalisa;
- Dalt, Lorenzo Da;
- Nour, Jasmine;
- Baragetti, Andrea;
- Uboldi, Patrizia;
- Idini, Alessandra;
- Wuhrer, Manfred;
- Beretta, Giangiacomo;
- Falck, David;
- Bonacina, Fabrizia;
- Norata, Giuseppe Danilo
Publication type:
Article