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Decoding the genetic program of micronucleus formation: linking chromosomal instability to human disease.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01869-2
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- Article
Influence of Bilberry Extract on Neuronal Cell Toxicity.
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- Biology (2079-7737), 2024, v. 13, n. 6, p. 376, doi. 10.3390/biology13060376
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- Article
OCT1-dependent uptake of structurally diverse pyrrolizidine alkaloids in human liver cells is crucial for their genotoxic and cytotoxic effects.
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- Archives of Toxicology, 2023, v. 97, n. 12, p. 3259, doi. 10.1007/s00204-023-03591-4
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- Article
Heme Oxygenase-1 and Its Role in Colorectal Cancer.
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- Antioxidants, 2023, v. 12, n. 11, p. 1989, doi. 10.3390/antiox12111989
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- Article
Potency ranking of pyrrolizidine alkaloids in metabolically competent human liver cancer cells and primary human hepatocytes using a genotoxicity test battery.
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- Archives of Toxicology, 2023, v. 97, n. 5, p. 1413, doi. 10.1007/s00204-023-03482-8
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- Article
DNA Alkylation Damage by Nitrosamines and Relevant DNA Repair Pathways.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4684, doi. 10.3390/ijms24054684
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- Article
Specification and Simplification of Analytical Methods to Determine Wine Color.
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- Processes, 2022, v. 10, n. 12, p. 2707, doi. 10.3390/pr10122707
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- Article
p53 triggers mitochondrial apoptosis following DNA damage-dependent replication stress by the hepatotoxin methyleugenol.
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- Cell Death & Disease, 2022, v. 13, n. 11, p. 1, doi. 10.1038/s41419-022-05446-9
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- Article
The Essential Role of Rac1 Glucosylation in Clostridioides difficile Toxin B-Induced Arrest of G1-S Transition.
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- Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.846215
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- Article
Repair of O<sup>6</sup>-carboxymethylguanine adducts by O<sup>6</sup>-methylguanine-DNA methyltransferase in human colon epithelial cells.
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- Carcinogenesis, 2021, v. 42, n. 8, p. 1110, doi. 10.1093/carcin/bgab049
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- Article
Chronic intestinal inflammation drives colorectal tumor formation triggered by dietary heme iron in vivo.
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- Archives of Toxicology, 2021, v. 95, n. 7, p. 2507, doi. 10.1007/s00204-021-03064-6
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- Article
Natural Merosesquiterpenes Activate the DNA Damage Response via DNA Strand Break Formation and Trigger Apoptotic Cell Death in p53-Wild-Type and Mutant Colorectal Cancer.
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- Cancers, 2021, v. 13, n. 13, p. 3282, doi. 10.3390/cancers13133282
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- Article
Synthesis and in vitro characterization of the genotoxic, mutagenic and cell-transforming potential of nitrosylated heme.
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- Archives of Toxicology, 2020, v. 94, n. 11, p. 3911, doi. 10.1007/s00204-020-02846-8
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- Article
Heme oxygenase 1 protects human colonocytes against ROS formation, oxidative DNA damage and cytotoxicity induced by heme iron, but not inorganic iron.
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- Cell Death & Disease, 2020, v. 11, n. 9, p. 1, doi. 10.1038/s41419-020-02950-8
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- Article
Targeting Altered Energy Metabolism in Colorectal Cancer: Oncogenic Reprogramming, the Central Role of the TCA Cycle and Therapeutic Opportunities.
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- Cancers, 2020, v. 12, n. 7, p. 1731, doi. 10.3390/cancers12071731
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- Article
Switching off DNA repair—how colorectal cancer evades targeted therapies through adaptive mutability.
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- Signal Transduction & Targeted Therapy, 2020, v. 5, n. 1, p. 1, doi. 10.1038/s41392-020-0120-3
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- Article
Lipoic Acid Synergizes with Antineoplastic Drugs in Colorectal Cancer by Targeting p53 for Proteasomal Degradation.
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- Cells (2073-4409), 2019, v. 8, n. 8, p. 794, doi. 10.3390/cells8080794
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- Article
Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O<sup>6</sup>-methylguanine in vivo.
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- Archives of Toxicology, 2019, v. 93, n. 2, p. 559, doi. 10.1007/s00204-018-2355-0
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- Article
Sensitivity of CD3/CD28-stimulated versus non-stimulated lymphocytes to ionizing radiation and genotoxic anticancer drugs: key role of ATM in the differential radiation response.
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- Cell Death & Disease, 2018, v. 9, n. 11, p. 1, doi. 10.1038/s41419-018-1095-7
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- Article
Trendbericht Lebensmittelchemie 2017.
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- Nachrichten aus der Chemie, 2018, v. 66, n. 3, p. 336, doi. 10.1002/nadc.20184071901
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- Article
DNA damage response curtails detrimental replication stress and chromosomal instability induced by the dietary carcinogen PhIP.
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- Nucleic Acids Research, 2016, v. 44, n. 21, p. 10259, doi. 10.1093/nar/gkw791
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- Article
Nitroglycerin induces DNA damage and vascular cell death in the setting of nitrate tolerance.
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- Basic Research in Cardiology, 2016, v. 111, n. 4, p. 1, doi. 10.1007/s00395-016-0571-4
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- Article
Lipoic acid induces p53-independent cell death in colorectal cancer cells and potentiates the cytotoxicity of 5-fluorouracil.
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- Archives of Toxicology, 2015, v. 89, n. 10, p. 1829, doi. 10.1007/s00204-014-1434-0
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- Article
DNA repair by MGMT, but not AAG, causes a threshold in alkylation-induced colorectal carcinogenesis.
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- Carcinogenesis, 2015, v. 36, n. 10, p. 1235, doi. 10.1093/carcin/bgv114
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- Article
Lipoic acid inhibits the DNA repair protein O<sup>6</sup>-methylguanine-DNA methyltransferase (MGMT) and triggers its depletion in colorectal cancer cells with concomitant autophagy induction.
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- Carcinogenesis, 2015, v. 36, n. 8, p. 817, doi. 10.1093/carcin/bgv070
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- Article
The eucalyptus oil ingredient 1,8-cineol induces oxidative DNA damage.
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- Archives of Toxicology, 2015, v. 89, n. 5, p. 797, doi. 10.1007/s00204-014-1281-z
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- Article
DNA Double Strand Breaks as Predictor of Efficacy of the Alpha-Particle Emitter Ac-225 and the Electron Emitter Lu-177 for Somatostatin Receptor Targeted Radiotherapy.
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- PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088239
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- Article
Efficient Delivery of p53 and Cytochrome C by Supramolecular Assembly of a Dendritic Multi-Domain Delivery System.
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- Advanced Healthcare Materials, 2013, v. 2, n. 12, p. 1620, doi. 10.1002/adhm.201200419
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- Article
O6-methylguanine-DNA methyltransferase in the defense against N-nitroso compounds and colorectal cancer.
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- Carcinogenesis, 2013, v. 34, n. 11, p. 2435, doi. 10.1093/carcin/bgt275
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- Article
A Cell-Permeable Fusion Protein Based on <i>Clostridium botulinum</i> C2 Toxin for Delivery of p53 Tumorsuppressor into Cancer Cells.
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- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0072455
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- Article
Internalization of biotinylated compounds into cancer cells is promoted by a molecular Trojan horse based upon core streptavidin and clostridial C2 toxin.
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- Naunyn-Schmiedeberg's Archives of Pharmacology, 2011, v. 383, n. 3, p. 263, doi. 10.1007/s00210-010-0585-7
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- Article
The C2-streptavidin delivery system promotes the uptake of biotinylated molecules in macrophages and T-leukemia cells.
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- Biological Chemistry, 2010, v. 391, n. 12, p. 1315, doi. 10.1515/BC.2010.132
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- Article
The C2-streptavidin delivery system promotes the uptake of biotinylated molecules in macrophages and T-leukemia cells.
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- Biological Chemistry, 2010, v. 391, n. 11, p. 1315, doi. 10.1515/BC.2010.132
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- Article
Selective and specific internalization of clostridial C3 ADP-ribosyltransferases into macrophages and monocytes.
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- Cellular Microbiology, 2010, v. 12, n. 2, p. 233, doi. 10.1111/j.1462-5822.2009.01393.x
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Quantitative analysis of the binding affinity of poly(ADP-ribose) to specific binding proteins as a function of chain length.
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- Nucleic Acids Research, 2007, v. 35, n. 21, p. e143, doi. 10.1093/nar/gkm944
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- Article