Found: 18
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Phase I study assessing the mass balance, pharmacokinetics, and excretion of [14C]-pevonedistat, a NEDD8-activating enzyme inhibitor in patients with advanced solid tumors.
- Published in:
- Investigational New Drugs, 2021, v. 39, n. 2, p. 488, doi. 10.1007/s10637-020-01017-x
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- Publication type:
- Article
Phase Ib study of pevonedistat, a NEDD8-activating enzyme inhibitor, in combination with docetaxel, carboplatin and paclitaxel, or gemcitabine, in patients with advanced solid tumors.
- Published in:
- Investigational New Drugs, 2019, v. 37, n. 1, p. 87, doi. 10.1007/s10637-018-0610-0
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- Publication type:
- Article
A phase I study of the investigational NEDD8-activating enzyme inhibitor pevonedistat (TAK-924/MLN4924) in patients with metastatic melanoma.
- Published in:
- Investigational New Drugs, 2016, v. 34, n. 4, p. 439, doi. 10.1007/s10637-016-0348-5
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- Publication type:
- Article
Pharmacokinetic-pharmacodynamic modeling of the effect of varenicline on nicotine craving in adult smokers.
- Published in:
- 2015
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- Publication type:
- journal article
Nonlinear Response Surface and Mixture Experiment Methodologies Applied to the Study of Synergism.
- Published in:
- Biometrical Journal, 2004, v. 46, n. 1, p. 56
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- Publication type:
- Article
Parabolic growth patterns in 96-well plate cell growth experiments.
- Published in:
- In Vitro Cellular & Developmental Biology Animal, 1999, v. 35, n. 5, p. 270, doi. 10.1007/s11626-999-0071-z
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- Publication type:
- Article
Pevonedistat ( MLN4924), a First-in-Class NEDD8-activating enzyme inhibitor, in patients with acute myeloid leukaemia and myelodysplastic syndromes: a phase 1 study.
- Published in:
- British Journal of Haematology, 2015, v. 169, n. 4, p. 534, doi. 10.1111/bjh.13323
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- Publication type:
- Article
Medical Castration Using the Investigational Oral GnRH Antagonist TAK-385 (Relugolix): Phase 1 Study in Healthy Males.
- Published in:
- 2015
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- Publication type:
- journal article
Population pharmacokinetic analysis of varenicline in adult smokers.
- Published in:
- British Journal of Clinical Pharmacology, 2009, v. 68, n. 5, p. 669, doi. 10.1111/j.1365-2125.2009.03520.x
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- Publication type:
- Article
Orexin 2 receptor‐selective agonist danavorexton (TAK‐925) promotes wakefulness in non‐human primates and healthy individuals.
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- Journal of Sleep Research, 2023, v. 32, n. 5, p. 1, doi. 10.1111/jsr.13878
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- Publication type:
- Article
Pharmacokinetics, pharmacodynamics and safety assessment of multiple doses of soticlestat in healthy volunteers.
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- British Journal of Clinical Pharmacology, 2022, v. 88, n. 6, p. 2899, doi. 10.1111/bcp.15225
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- Publication type:
- Article
Safety, tolerability, pharmacokinetics, pharmacodynamics, bioavailability and food effect of single doses of soticlestat in healthy subjects.
- Published in:
- British Journal of Clinical Pharmacology, 2021, v. 87, n. 11, p. 4354, doi. 10.1111/bcp.14854
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- Publication type:
- Article
Population pharmacokinetics of pevonedistat alone or in combination with standard of care in patients with solid tumours or haematological malignancies.
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- British Journal of Clinical Pharmacology, 2019, v. 85, n. 11, p. 2568, doi. 10.1111/bcp.14078
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- Publication type:
- Article
Effect of CYP3A inhibitors on the pharmacokinetics of pevonedistat in patients with advanced solid tumours.
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- British Journal of Clinical Pharmacology, 2019, v. 85, n. 7, p. 1464, doi. 10.1111/bcp.13915
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- Publication type:
- Article
Lack of Pharmacokinetic and Pharmacodynamic Interactions Between a Smoking Cessation Therapy, Varenicline, and Warfarin: An In Vivo and In Vitro Study.
- Published in:
- Journal of Clinical Pharmacology, 2007, v. 47, n. 11, p. 1421, doi. 10.1177/0091270007307574
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- Publication type:
- Article
Multiple-Dose Pharmacokinetics of the Selective Nicotinic Receptor Partial Agonist, Varenicline, in Healthy Smokers.
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- Journal of Clinical Pharmacology, 2006, v. 46, n. 12, p. 1439, doi. 10.1177/0091270006292624
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- Publication type:
- Article
Pharmacokinetics, Safety, and Tolerability After Single and Multiple Oral Doses of Varenicline in Elderly Smokers.
- Published in:
- Journal of Clinical Pharmacology, 2006, v. 46, n. 11, p. 1234, doi. 10.1177/0091270006291837
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- Publication type:
- Article
Single-Dose Pharmacokinetics of Varenicline, a Selective Nicotinic Receptor Partial Agonist, in Healthy Smokers and Nonsmokers.
- Published in:
- Journal of Clinical Pharmacology, 2006, v. 46, n. 9, p. 991, doi. 10.1177/0091270006290669
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- Publication type:
- Article