Works by Facchini, Peter J

Results: 54

Benzylisoquinoline Alkaloids Biosynthesis in Sacred Lotus.

Published in:

Molecules, 2018, v. 23, n. 11, p. 2899, doi. 10.3390/molecules23112899

By:

Menéndez-Perdomo, Ivette M.;
Facchini, Peter J.

Publication type:

Article

Plant cell bioreactor for the production of protoberberine alkaloids from immobilized Thalictrum rugosum cultures.

Published in:

Biotechnology & Bioengineering, 1991, v. 37, n. 5, p. 397, doi. 10.1002/bit.260370502

By:

Facchini, Peter J.;
Dicosmo, Frank

Publication type:

Article

Gene transcript and metabolite profiling of elicitor-induced opium poppy cell cultures reveals the coordinate regulation of primary and secondary metabolism.

Published in:

Planta: An International Journal of Plant Biology, 2007, v. 225, n. 5, p. 1085, doi. 10.1007/s00425-006-0419-5

By:

Zulak, Katherine G.;
Cornish, Anthony;
Daskalchuk, Timothy E.;
Deyholos, Michael K.;
Goodenowe, Dayan B.;
Gordon, Paul M. K.;
Klassen, Darren;
Pelcher, Lawrence E.;
Sensen, Christoph W.;
Facchini, Peter J.

Publication type:

Article

Elevated tyrosine decarboxylase and tyramine hydroxycinnamoyltransferase levels increase wound-induced tyramine-derived hydroxycinnamic acid amide accumulation in transgenic tobacco leaves.

Published in:

Planta: An International Journal of Plant Biology, 2005, v. 221, n. 6, p. 904, doi. 10.1007/s00425-005-1484-x

By:

Hagel, Jillian M.;
Facchini, Peter J.

Publication type:

Article

Isolation and partial characterization of norcoclaurine synthase, the first committed step in benzylisoquinoline alkaloid biosynthesis, from opium poppy.

Published in:

Planta: An International Journal of Plant Biology, 2001, v. 213, n. 6, p. 898, doi. 10.1007/s004250100581

By:

Samanani, Nailish;
Facchini, Peter J.

Publication type:

Article

Berberine bridge enzyme, a key branch-point enzyme in benzylisoquinoline alkaloid biosynthesis, contains a vacuolar sorting determinant.

Published in:

Planta: An International Journal of Plant Biology, 2001, v. 213, n. 6, p. 888, doi. 10.1007/s004250100582

By:

Bird, David A.;
Facchini, Peter J.

Publication type:

Article

Two ubiquitous aldo-keto reductases in the genus Papaver support a patchwork model for morphine pathway evolution.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07100-w

By:

Carr, Samuel C.;
Rehman, Fasih;
Hagel, Jillian M.;
Chen, Xue;
Ng, Kenneth K. S.;
Facchini, Peter J.

Publication type:

Article

Morphine Biosynthesis in Opium Poppy Involves Two Cell Types: Sieve Elements and Laticifers.

Published in:

Plant Cell, 2013, v. 25, n. 10, p. 4110, doi. 10.1105/tpc.113.115113

By:

Onoyovwe, Akpevwe;
Hagel, Jillian M.;
Chen, Xue;
Khan, Morgan F.;
Schriemer, David C.;
Facchini, Peter J.

Publication type:

Article

Molecular Origins of Functional Diversity in Benzylisoquinoline Alkaloid Methyltransferases.

Published in:

Frontiers in Plant Science, 2019, p. 1, doi. 10.3389/fpls.2019.01058

By:

Facchini, Peter J.;
Morris, Jeremy S.

Publication type:

Article

Elucidation of the mescaline biosynthetic pathway in peyote (Lophophora williamsii).

Published in:

Plant Journal, 2023, v. 116, n. 3, p. 635, doi. 10.1111/tpj.16447

By:

Watkins, Jacinta L.;
Li, Qiushi;
Yeaman, Sam;
Facchini, Peter J.

Publication type:

Article

PR10/Bet v1‐like Proteins as Novel Contributors to Plant Biochemical Diversity.

Published in:

ChemBioChem, 2021, v. 22, n. 2, p. 264, doi. 10.1002/cbic.202000354

By:

Morris, Jeremy S.;
Caldo, Kristian Mark P.;
Liang, Siyu;
Facchini, Peter J.

Publication type:

Article

Benzylisoquinoline Alkaloid Metabolism: A Century of Discovery and a Brave New World.

Published in:

Plant & Cell Physiology, 2013, v. 54, n. 5, p. 647, doi. 10.1093/pcp/pct020

By:

Hagel, Jillian M.;
Facchini, Peter J.

Publication type:

Article

Opium poppy and Madagascar periwinkle: model non-model systems to investigate alkaloid biosynthesis in plants.

Published in:

Plant Journal, 2008, v. 54, n. 4, p. 763, doi. 10.1111/j.1365-313X.2008.03438.x

By:

Facchini, Peter J.;
De Luca, Vincenzo

Publication type:

Article

The role of phloem sieve elements and laticifers in the biosynthesis and accumulation of alkaloids in opium poppy.

Published in:

Plant Journal, 2006, v. 47, n. 4, p. 547, doi. 10.1111/j.1365-313X.2006.02801.x

By:

Samanani, Nailish;
Alcantara, Joenel;
Bourgault, Richard;
Zulak, Katherine G.;
Facchini, Peter J.

Publication type:

Article

Molecular cloning and characterization of norcoclaurine synthase, an enzyme catalyzing the first committed step in benzylisoquinoline alkaloid biosynthesis.

Published in:

Plant Journal, 2004, v. 40, n. 2, p. 302, doi. 10.1111/j.1365-313X.2004.02210.x

By:

Samanani, Nailish;
Liscombe, David K.;
Facchini, Peter J.

Publication type:

Article

In vitro regeneration and genetic transformation of the berberine-producing plant, Thalictrum flavum ssp. glaucum.

Published in:

Physiologia Plantarum, 2002, v. 116, n. 1, p. 79, doi. 10.1034/j.1399-3054.2002.1160110.x

By:

Samanani, Nailish;
Park, Sang-Un;
Facchini, Peter J.

Publication type:

Article

Molecular cloning and characterization of a type III glutathione S-transferase from cell suspension cultures of opium poppy treated with a fungal elicitor.

Published in:

Physiologia Plantarum, 2000, v. 108, n. 1, p. 101, doi. 10.1034/j.1399-3054.2000.108001101.x

By:

Min Yu;
Facchini, Peter J.

Publication type:

Article

Benzylisoquinoline alkaloid analysis using high-resolution Orbitrap LC-MSn.

Published in:

Journal of Mass Spectrometry, 2021, v. 56, n. 2, p. 1, doi. 10.1002/jms.4683

By:

Menéndez-Perdomo, Ivette M.;
Hagel, Jillian M.;
Facchini, Peter J.

Publication type:

Article

Back to the plant: overcoming roadblocks to the microbial production of pharmaceutically important plant natural products.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2020, v. 47, n. 9/10, p. 815, doi. 10.1007/s10295-020-02300-9

By:

Ozber, Natali;
Watkins, Jacinta L.;
Facchini, Peter J.

Publication type:

Article

Production of methylparaben in Escherichia coli.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2019, v. 46, n. 1, p. 91, doi. 10.1007/s10295-018-2102-9

By:

Hagel, Jillian M.;
Chen, Xue;
Facchini, Peter J.

Publication type:

Article

Corrigendum: Molecular Origins of Functional Diversity in Benzylisoquinoline Alkaloid Methyltransferases.

Published in:

2019

By:

Morris, Jeremy S.;
Facchini, Peter J.

Publication type:

Correction Notice

Reconstitution of a 10-gene pathway for synthesis of the plant alkaloid dihydrosanguinarine in Saccharomyces cerevisiae.

Published in:

Nature Communications, 2014, v. 5, n. 2, p. 3283, doi. 10.1038/ncomms4283

By:

Fossati, Elena;
Ekins, Andrew;
Narcross, Lauren;
Zhu, Yun;
Falgueyret, Jean-Pierre;
Beaudoin, Guillaume A. W.;
Facchini, Peter J;
Martin, Vincent J. J.

Publication type:

Article

Tying the knot: occurrence and possible significance of gene fusions in plant metabolism and beyond.

Published in:

Journal of Experimental Botany, 2017, v. 68, n. 15, p. 4029, doi. 10.1093/jxb/erx152

By:

Hagel, Jillian M.;
Facchini, Peter J.

Publication type:

Article

Purine Permease-Type Benzylisoquinoline Alkaloid Transporters in Opium Poppy.

Published in:

Plant Physiology, 2019, v. 181, n. 3, p. 916, doi. 10.1104/pp.19.00565

By:

Dastmalchi, Mehran;
Limei Chang;
Rongji Chen;
Yu, Lisa;
Xue Chen;
Hagel, Jillian M.;
Facchini, Peter J.

Publication type:

Article

Isolation and Characterization of O-methyltransferases Involved in the Biosynthesis of Glaucine in Glaucium flavum.

Published in:

Plant Physiology, 2015, v. 169, n. 2, p. 1127, doi. 10.1104/pp.15.01240

By:

Limei Chang;
Hagel, Jillian M.;
Facchini, Peter J.

Publication type:

Article

Characterization of Three O-Methyltransferases Involved in Noscapine Biosynthesis in Opium Poppy.

Published in:

Plant Physiology, 2012, v. 159, n. 2, p. 618, doi. 10.1104/pp.112.194886

By:

Dang, Thu-Thuy T.;
Facchini, Peter J.

Publication type:

Article

Tyrosine Aminotransferase Contributes to Benzylisoquinoline Alkaloid Biosynthesis in Opium Poppy.

Published in:

Plant Physiology, 2011, v. 157, n. 3, p. 1067, doi. 10.1104/pp.111.185512

By:

Lee, Eun-Jeong;
Facchini, Peter J.

Publication type:

Article

Papaverine 7-O-demethylase, a novel 2-oxoglutarate/Fe2+-dependent dioxygenase from opium poppy.

Published in:

FEBS Letters, 2015, v. 589, n. 19PartB, p. 2701, doi. 10.1016/j.febslet.2015.07.042

By:

Farrow, Scott C.;
Facchini, Peter J.

Publication type:

Article

Cloning and characterization of canadine synthase involved in noscapine biosynthesis in opium poppy.

Published in:

FEBS Letters, 2014, v. 588, n. 1, p. 198, doi. 10.1016/j.febslet.2013.11.037

By:

Dang, Thu-Thuy T.;
Facchini, Peter J.

Publication type:

Article

Structural analysis of a ligand‐triggered intermolecular disulfide switch in a major latex protein from opium poppy.

Published in:

Acta Crystallographica: Section D, Structural Biology, 2024, v. 80, n. 9, p. 675, doi. 10.1107/S2059798324007733

By:

Carr, Samuel C.;
Facchini, Peter J.;
Ng, Kenneth K. S.

Publication type:

Article

Genes encoding norcoclaurine synthase occur as tandem fusions in the Papaveraceae.

Published in:

Scientific Reports, 2016, p. 39256, doi. 10.1038/srep39256

By:

Li, Jing;
Lee, Eun-Jeong;
Chang, Limei;
Facchini, Peter J.

Publication type:

Article

Role of the phloem in the biochemistry and ecophysiology of benzylisoquinoline alkaloid metabolism.

Published in:

Frontiers in Plant Science, 2013, v. 4, p. 1, doi. 10.3389/fpls.2013.00182

By:

Eun-Jeong Lee;
Hagel, Jillian M.;
Facchini, Peter J.

Publication type:

Article

Author Correction: Gene clustering and copy number variation in alkaloid metabolic pathways of opium poppy.

Published in:

2020

By:

Li, Qiushi;
Ramasamy, Sukanya;
Singh, Pooja;
Hagel, Jillian M.;
Dunemann, Sonja M.;
Chen, Xue;
Chen, Rongji;
Yu, Lisa;
Tucker, Joseph E.;
Facchini, Peter J.;
Yeaman, Sam

Publication type:

Correction Notice

Gene clustering and copy number variation in alkaloid metabolic pathways of opium poppy.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15040-2

By:

Li, Qiushi;
Ramasamy, Sukanya;
Singh, Pooja;
Hagel, Jillian M.;
Dunemann, Sonja M.;
Chen, Xue;
Chen, Rongji;
Yu, Lisa;
Tucker, Joseph E.;
Facchini, Peter J.;
Yeaman, Sam

Publication type:

Article

Transcriptome Profiling of Khat (Catha edulis) and Ephedra sinica Reveals Gene Candidates Potentially Involved in Amphetamine-Type Alkaloid Biosynthesis.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0119701

By:

Groves, Ryan A.;
Hagel, Jillian M.;
Zhang, Ye;
Kilpatrick, Korey;
Levy, Asaf;
Marsolais, Frédéric;
Lewinsohn, Efraim;
Sensen, Christoph W.;
Facchini, Peter J.

Publication type:

Article

Opium poppy: a model system to investigate alkaloid biosynthesis in plants.

Published in:

Canadian Journal of Botany, 2005, v. 83, n. 10, p. 1189, doi. 10.1139/b05-094

By:

Facchini, Peter J.;
Bird, David A.;
Bourgault, Richard;
Hagel, Jillian M.;
Liscombe, David K.;
MacLeod, Benjamin P.;
Zulak, Katherine G.

Publication type:

Article

Hydroxycinnamic acid amide metabolism: physiology and biochemistry.

Published in:

Canadian Journal of Botany, 2002, v. 80, n. 6, p. 577, doi. 10.1139/b02-065

By:

Facchini, Peter J;
Hagel, Jillian;
Zulak, Katherine G

Publication type:

Article

Elucidation of the (R)-enantiospecific benzylisoquinoline alkaloid biosynthetic pathways in sacred lotus (Nelumbo nucifera).

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-29415-0

By:

Menéndez-Perdomo, Ivette M.;
Facchini, Peter J.

Publication type:

Article

Codeinone reductase isoforms with differential stability, efficiency and product selectivity in opium poppy.

Published in:

Plant Journal, 2018, v. 95, n. 4, p. 631, doi. 10.1111/tpj.13975

By:

Dastmalchi, Mehran;
Chang, Limei;
Torres, Miguel A.;
Ng, Kenneth K. S.;
Facchini, Peter J.

Publication type:

Article

Heterodimeric O‐methyltransferases involved in the biosynthesis of noscapine in opium poppy.

Published in:

Plant Journal, 2018, v. 95, n. 2, p. 252, doi. 10.1111/tpj.13947

By:

Park, Myung R.;
Chen, Xue;
Lang, Dean E.;
Ng, Kenneth K. S.;
Facchini, Peter J.

Publication type:

Article

Short-chain dehydrogenase/reductase catalyzing the final step of noscapine biosynthesis is localized to laticifers in opium poppy.

Published in:

Plant Journal, 2014, v. 77, n. 2, p. 173, doi. 10.1111/tpj.12379

By:

Chen, Xue;
Facchini, Peter J.

Publication type:

Article

Systematic silencing of benzylisoquinoline alkaloid biosynthetic genes reveals the major route to papaverine in opium poppy.

Published in:

Plant Journal, 2012, v. 72, n. 2, p. 331, doi. 10.1111/j.1365-313X.2012.05084.x

By:

Desgagné-Penix, Isabel;
Facchini, Peter J.

Publication type:

Article

Systematic knockdown of morphine pathway enzymes in opium poppy using virus-induced gene silencing.

Published in:

Plant Journal, 2012, v. 69, n. 6, p. 1052, doi. 10.1111/j.1365-313X.2011.04855.x

By:

Wijekoon, Champa P.;
Facchini, Peter J.

Publication type:

Article

Targeted metabolite and transcript profiling for elucidating enzyme function: isolation of novel N-methyltransferases from three benzylisoquinoline alkaloid-producing species.

Published in:

Plant Journal, 2009, v. 60, n. 4, p. 729, doi. 10.1111/j.1365-313X.2009.03980.x

By:

Liscombe, David K.;
Ziegler, Jörg;
Schmidt, Jürgen;
Ammer, Christian;
Facchini, Peter J.

Publication type:

Article

Alkaloid binding to opium poppy major latex proteins triggers structural modification and functional aggregation.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34313-6

By:

Ozber, Natali;
Carr, Samuel C.;
Morris, Jeremy S.;
Liang, Siyu;
Watkins, Jacinta L.;
Caldo, Kristian M.;
Hagel, Jillian M.;
Ng, Kenneth K. S.;
Facchini, Peter J.

Publication type:

Article

Stereochemical inversion of (S)-reticuline by a cytochrome P450 fusion in opium poppy.

Published in:

Nature Chemical Biology, 2015, v. 11, n. 9, p. 728, doi. 10.1038/nchembio.1879

By:

Farrow, Scott C;
Hagel, Jillian M;
Beaudoin, Guillaume A W;
Burns, Darcy C;
Facchini, Peter J

Publication type:

Article

Acetylation serves as a protective group in noscapine biosynthesis in opium poppy.

Published in:

Nature Chemical Biology, 2015, v. 11, n. 2, p. 104, doi. 10.1038/nchembio.1717

By:

Dang, Thu-Thuy T;
Chen, Xue;
Facchini, Peter J

Publication type:

Article

Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy.

Published in:

Nature Chemical Biology, 2010, v. 6, n. 4, p. 273, doi. 10.1038/nchembio.317

By:

Hagel, Jillian M.;
Facchini, Peter J.

Publication type:

Article

Functional diversity of 2-oxoglutarate/Fe(II)-dependent dioxygenases in plant metabolism.

Published in:

Frontiers in Plant Science, 2014, v. 5, p. 1, doi. 10.3389/fpls.2014.00524

By:

Farrow, Scott C.;
Facchini, Peter J.

Publication type:

Article

Perspectives in Experimental Botany. mediated transformation of opium poppy, L., and California poppy, Cham., root cultures.

Published in:

Journal of Experimental Botany, 2000, v. 51, n. 347

By:

Park, Sang&hyphen;Un;
Sang-Un Park;
Facchini, Peter J.

Publication type:

Article